New Frontiers of MR-based Techniques in Multiple Sclerosis

New Frontiers of MR-based Techniques in Multiple Sclerosis PDF Author: Massimo Filippi
Publisher: Springer Science & Business Media
ISBN: 8847022371
Category : Medical
Languages : en
Pages : 174

Get Book Here

Book Description
In the past few years there have been impressive advances in the implementation of modern MRI techniques for the assessment of MS patients with the ultimate goal to define MRI markers of MS evolution. The authors of this volume not only review these new techniques, such as magnetization transfer (MT) MRI, diffusion-weighted (DW) MRI and proton MR spectroscopy (MRS), that are increasingly being used to monitor MS evolution, but also those, such as functional MRI (fMRI), cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, that are emerging as additional promising tools for improving our understanding of MS pathophysiology. Strengths and weaknesses of all these modern quantitative MRI techniques for the study of MS are extensively covered in this book. The book also provides a valuable summary of the state of the art.

New Frontiers of MR-based Techniques in Multiple Sclerosis

New Frontiers of MR-based Techniques in Multiple Sclerosis PDF Author: Massimo Filippi
Publisher: Springer Science & Business Media
ISBN: 8847022371
Category : Medical
Languages : en
Pages : 174

Get Book Here

Book Description
In the past few years there have been impressive advances in the implementation of modern MRI techniques for the assessment of MS patients with the ultimate goal to define MRI markers of MS evolution. The authors of this volume not only review these new techniques, such as magnetization transfer (MT) MRI, diffusion-weighted (DW) MRI and proton MR spectroscopy (MRS), that are increasingly being used to monitor MS evolution, but also those, such as functional MRI (fMRI), cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, that are emerging as additional promising tools for improving our understanding of MS pathophysiology. Strengths and weaknesses of all these modern quantitative MRI techniques for the study of MS are extensively covered in this book. The book also provides a valuable summary of the state of the art.

Multiple Sclerosis

Multiple Sclerosis PDF Author: Michael Olek
Publisher: Springer Science & Business Media
ISBN: 1592598552
Category : Medical
Languages : en
Pages : 253

Get Book Here

Book Description
A synthesis of current concepts about the evaluation, treatment, and future directions in MS. On the evaluation side, the authors review the use of MRI, magnetic resonance spectroscopy, functional MRI, and three-dimensional MRI, and consider the rapidly developing body of pathologic information they have yielded. On the treatment side, the focus is on recently approved medications (Novantrone), new indications for medications (CHAMPS Trial), medications in development (Oral Interferon Tau, Oral Copaxone, and Oral Cellcept), immunosuppressive therapy for both progressive disease and symptomatic therapy; the current medications for treating relapsing-remitting MS (Avonex, Betaseron, and Copaxone) are also discussed. For future directions, the authors present the current best thinking, as well as the latest discoveries in immunology relating to MS, including groundbreaking B-cell research and its applications to specific immunotherapies, and the use of immune markers for tracking the disease.

MR Imaging in White Matter Diseases of the Brain and Spinal Cord

MR Imaging in White Matter Diseases of the Brain and Spinal Cord PDF Author: Massimo Filippi
Publisher: Springer Science & Business Media
ISBN: 3540276440
Category : Medical
Languages : en
Pages : 463

Get Book Here

Book Description
In recent decades, the use of neuroimaging techniques has resulted in outstanding progress in the diagnosis and management of neurological diseases, and this is particularly true of those diseases that affect the white matter of the brain and spinal cord. This book, written by internationally acclaimed experts, comprises a series of comprehensive and up-to-date reviews on the use of MR imaging in these major neurological conditions. The diverse available MR techniques, such as magnetization transfer MRI, diffusion-weighted MRI, MR spectroscopy, functional MRI, cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, offer an extraordinarily powerful means of gaining fundamental in vivo insights into disease processes. The strengths and weaknesses of all these techniques in the study of multiple sclerosis and other relevant diseases are extensively considered. After an introductory section on neuroimaging technology, subsequent sections address disorders of myelination, demyelinating diseases, immune-mediated disorders, and white matter disorders related to aging and other conditions. This book provides a valuable summary of the state of the art in the field, and defines important areas for future research.

Normal-appearing White and Grey Matter Damage in Multiple Sclerosis

Normal-appearing White and Grey Matter Damage in Multiple Sclerosis PDF Author: M. Filippi
Publisher: Springer Science & Business Media
ISBN: 8847021278
Category : Medical
Languages : en
Pages : 184

Get Book Here

Book Description
In the last few years, increasing effort has been devoted to better define the characteristics of tissue damage occurring outside MRI-visible lesions in patients with multiple sclerosis (MS) and, as a consequence, to improve our understanding of the disease pathobiology and of the mechanisms leading to the accumulation of irreversible disability. This book provides an updated review of the results obtained by leading research groups in this field. The potential clinical applications of what has been shown so far, as well as the areas for future research in the study of normal-appearing white and gray matter damage in MS are extensively discussed, making this book a valuable tool for clinical neurologists who are involved in the daily-life care of MS patients and for neuroscientists involved in MS research.

Magnetism in Medicine

Magnetism in Medicine PDF Author: Wilfried Andrä
Publisher: John Wiley & Sons
ISBN: 3527610189
Category : Medical
Languages : en
Pages : 655

Get Book Here

Book Description
This second, completely updated and extended edition of the only reference work in this growing field of medical physics focuses on biomagnetic instrumentation as well as applications in cardiology and neurology. New chapters have been added on fetal magnetography and magnetic field therapy, as well as the safety aspects of magnetic fields. Written by well-known specialists from Germany, USA, Canada, Japan, the Netherlands and Scandinavia, the result is a manual for researchers in this field as well as for those who apply modern methods based on magnetism in medical practice. It equally provides a detailed overview for newcomers to the field as well as for experts familiar with only one part of the area.

Journal of the American Medical Association

Journal of the American Medical Association PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 652

Get Book Here

Book Description


Brain Network Analysis

Brain Network Analysis PDF Author: Moo K. Chung
Publisher: Cambridge University Press
ISBN: 110718486X
Category : Computers
Languages : en
Pages : 343

Get Book Here

Book Description
This coherent mathematical and statistical approach aimed at graduate students incorporates regression and topology as well as graph theory.

American Book Publishing Record

American Book Publishing Record PDF Author:
Publisher:
ISBN:
Category : American literature
Languages : en
Pages : 746

Get Book Here

Book Description


Automatic methods for multiple sclerosis new lesions detection and segmentation

Automatic methods for multiple sclerosis new lesions detection and segmentation PDF Author: Olivier Commowick
Publisher: Frontiers Media SA
ISBN: 2832520375
Category : Science
Languages : en
Pages : 132

Get Book Here

Book Description


Magnetic Resonance Spectroscopy in Multiple Sclerosis

Magnetic Resonance Spectroscopy in Multiple Sclerosis PDF Author: M. Filippi
Publisher: Springer Science & Business Media
ISBN: 884702109X
Category : Medical
Languages : en
Pages : 180

Get Book Here

Book Description
Recent years have witnessed dramatic advances in the development and use of magnetic resonance imaging (MRI) techniques that can provide quantitative measures with some degree of pathological specificity for the heterogeneous substrates of multiple sclerosis (MS). Magnetic resonance spectroscopy (MRS) is one of the most promising of these techniques. Thanks to MRS, axonal damage is no longer considered an end-stage phenomenon typical of only the most destructive lesions and the most unfortunate cases, but rather as a major component of the MS pathology of lesions and normal-appearing white matter at all the phases of the disease. This new concept is rapidly changing our understanding of MS pathophysiology and, as a consequence, the therapeutic strategies to modify the disease course favorably. Many of the authors have pionereed the use of MRS in MS, thus contributing to the foundation of the "axonal hypothesis".