Drug Discovery Targeting Drug-Resistant Bacteria

Drug Discovery Targeting Drug-Resistant Bacteria PDF Author: Prashant Kesharwani
Publisher: Academic Press
ISBN: 0128184817
Category : Medical
Languages : en
Pages : 434

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Book Description
Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. - Written by scientists with extensive industrial experience in drug discovery - Provides a balanced view of the field, including its challenges and future directions - Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war

Drug Discovery Targeting Drug-Resistant Bacteria

Drug Discovery Targeting Drug-Resistant Bacteria PDF Author: Prashant Kesharwani
Publisher: Academic Press
ISBN: 0128184817
Category : Medical
Languages : en
Pages : 434

Get Book Here

Book Description
Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. - Written by scientists with extensive industrial experience in drug discovery - Provides a balanced view of the field, including its challenges and future directions - Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war

New Approaches Against Drug-Resistant M. tuberculosis

New Approaches Against Drug-Resistant M. tuberculosis PDF Author: Maria Rosalia Pasca
Publisher: Frontiers Media SA
ISBN: 288966869X
Category : Science
Languages : en
Pages : 153

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Book Description


Global Tuberculosis Report 2014

Global Tuberculosis Report 2014 PDF Author: World Health Organization
Publisher:
ISBN: 9789241564809
Category : Medical economics
Languages : en
Pages : 0

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Book Description
Some volumes for 2014 includes CD-ROM for 2014 key indicators.

The New Profile of Drug-Resistant Tuberculosis in Russia

The New Profile of Drug-Resistant Tuberculosis in Russia PDF Author: Russian Academy of Medical Sciences
Publisher: National Academies Press
ISBN: 0309225051
Category : Medical
Languages : en
Pages : 158

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Book Description
An estimated 2 billion people, one third of the global population, are infected with Mycobacterium tuberculosis, the bacterium that causes tuberculosis. Spread through the air, this infectious disease killed 1.7 million in 2009, and is the leading killer of people with HIV. Tuberculosis (TB) is also a disease of poverty-the vast majority of tuberculosis deaths occur in the developing world. Exacerbating the devastation caused by TB is the growing threat of drug-resistant forms of the disease in many parts of the world. Drug-resistant tuberculosis presents a number of significant challenges in terms of controlling its spread, diagnosing patients quickly and accurately, and using drugs to treat patients effectively. In Russia in recent decades, the rise of these strains of TB, resistant to standard antibiotic treatment, has been exacerbated by the occurrence of social, political, and economic upheavals. The Institute of Medicine (IOM) Forum on Drug Discovery, Development, and Translation, in conjunction with the Russian Academy of Medical Sciences held a workshop to discuss ways to fight the growing threat of drug-resistant TB. The New Profile of Drug-Resistant Tuberculosis in Russia: A Global and Local Perspective: Summary of a Joint Workshop presents information from experts on the nature of this threat and how it can be addressed by exploring various treatment and diagnostic options.

Global Tuberculosis Report 2018

Global Tuberculosis Report 2018 PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241565640
Category : Medical
Languages : en
Pages : 277

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Book Description
WHO has published a global TB report every year since 1997. The main aim of the report is to provide a comprehensive and up-to-date assessment of the TB epidemic and of progress in prevention diagnosis and treatment of the disease at global regional and country levels. This is done in the context of recommended global TB strategies and targets endorsed by WHO?s Member States and broader development goals set by the United Nations (UN). The 2018 edition of the global TB report was released on 18 September in the lead up to the first-ever UN High Level Meeting on TB on 26 September 2018.

Global Tuberculosis Report 2016

Global Tuberculosis Report 2016 PDF Author: World Health Organization
Publisher:
ISBN: 9789241565394
Category : Medical
Languages : en
Pages : 0

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Book Description
This global tuberculosis report is the first to be produced in the era of the SDGs and the End TB Strategy. It provides an assessment of the TB epidemic and progress in TB diagnosis, treatment, and prevention efforts as well as an overview of TB-specific financing and research. It also discusses the broader agenda of universal health coverage, social protection, and other SDGs that have an impact on health. Data was available for 202 countries and territories that account for over 99% of the world's population and TB cases.

Guidelines for the Programmatic Management of Drug-resistant Tuberculosis

Guidelines for the Programmatic Management of Drug-resistant Tuberculosis PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241547588
Category : Business & Economics
Languages : en
Pages : 271

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Book Description
The emergence of extensively drug-resistant strains of tuberculosis, especially in countries with a high prevalence of human immunodeficiency virus, is a serious threat to global public health and jeopardizes efforts to effectively control the disease. This publication offers updated recommendations for the diagnosis and management of drug-resistant tuberculosis in a variety of geographical, economic and social settings, and the recording of data that enables the monitoring and evaluation of programs.--Publisher's description.

Understanding Tuberculosis

Understanding Tuberculosis PDF Author: Pere-Joan Cardona
Publisher: BoD – Books on Demand
ISBN: 9533079487
Category : Medical
Languages : en
Pages : 390

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Book Description
In 1957, a Streptomyces strain, the ME/83 (S.mediterranei), was isolated in the Lepetit Research Laboratories from a soil sample collected at a pine arboretum near Saint Raphael, France. This drug was the base for the chemotherapy with Streptomicine. The euphoria generated by the success of this regimen lead to the idea that TB eradication would be possible by the year 2000. Thus, any further drug development against TB was stopped. Unfortunately, the lack of an accurate administration of these drugs originated the irruption of the drug resistance in Mycobacterium tuberculosis. Once the global emergency was declared in 1993, seeking out new drugs became urgent. In this book, diverse authors focus on the development and the activity of the new drug families.

Laboratory Methods for Clinical and Public Health

Laboratory Methods for Clinical and Public Health PDF Author: George P. Kubica
Publisher:
ISBN:
Category : Medical bacteriology
Languages : en
Pages : 96

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Book Description


Guidelines for the Programmatic Management of Drug-Resistant Tuberculosis

Guidelines for the Programmatic Management of Drug-Resistant Tuberculosis PDF Author: World Health Organization
Publisher:
ISBN: 9789241501583
Category : Medical
Languages : en
Pages : 0

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Book Description
This 2011 update of Guidelines for the programmatic management of drug-resistant tuberculosis is intended as a tool for use by public health professionals working in response to the Sixty-second World Health Assembly's resolution on prevention and control of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis. Resolution WHA62.15, adopted in 2009, calls on Member States to develop a comprehensive framework for the management and care of patients with drug-resistant TB. The recommendations contained in these guidelines address the most topical questions concerning the programmatic management of drug-resistant TB: case-finding, multidrug resistance, treatment regimens, monitoring the response to treatment, and selecting models of care. The guidelines primarily target staff and medical practitioners working in TB treatment and control, and partners and organizations providing technical and financial support for care of drug-resistant TB in settings where resources are limited.