Neuroprotection and Neuroregeneration for Retinal Diseases

Neuroprotection and Neuroregeneration for Retinal Diseases PDF Author: Toru Nakazawa
Publisher: Springer
ISBN: 443154965X
Category : Medical
Languages : en
Pages : 351

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Book Description
This book provides the latest findings on neuroprotection and neuroregeneration as potential therapeutic strategies for various eye diseases, namely, glaucoma, age-related macular degeneration (AMD), retinal detachment, and retinitis pigmentosa. Glaucoma is one of the main causes of blindness throughout the world, and other diseases such as AMD and retinitis pigmentosa also lead to loss of vision. All these conditions are characterized by degeneration of specific retinal cell types, making it essential to establish treatments to protect retinal neurons and the optic nerve. With that aim in mind, this book explains the mechanisms underlying aforementioned diseases and their experimental models. The novel strategy proposals for the treatment of retinal diseases based on the concept of neuroprotection are also discussed in the main body of the text, while the section on regenerative research discusses optic nerve regeneration, endothelial progenitor cells, and iPS cells. This book is recommended as a professional reference work for all doctors and trainees in the field of ophthalmology who are interested in neuroprotective and neuroregenerative treatments.

Neuroprotection and Neuroregeneration for Retinal Diseases

Neuroprotection and Neuroregeneration for Retinal Diseases PDF Author: Toru Nakazawa
Publisher: Springer
ISBN: 443154965X
Category : Medical
Languages : en
Pages : 351

Get Book Here

Book Description
This book provides the latest findings on neuroprotection and neuroregeneration as potential therapeutic strategies for various eye diseases, namely, glaucoma, age-related macular degeneration (AMD), retinal detachment, and retinitis pigmentosa. Glaucoma is one of the main causes of blindness throughout the world, and other diseases such as AMD and retinitis pigmentosa also lead to loss of vision. All these conditions are characterized by degeneration of specific retinal cell types, making it essential to establish treatments to protect retinal neurons and the optic nerve. With that aim in mind, this book explains the mechanisms underlying aforementioned diseases and their experimental models. The novel strategy proposals for the treatment of retinal diseases based on the concept of neuroprotection are also discussed in the main body of the text, while the section on regenerative research discusses optic nerve regeneration, endothelial progenitor cells, and iPS cells. This book is recommended as a professional reference work for all doctors and trainees in the field of ophthalmology who are interested in neuroprotective and neuroregenerative treatments.

The Retina in Health and Disease

The Retina in Health and Disease PDF Author: Maurice Ptito
Publisher: Mdpi AG
ISBN: 9783036526539
Category : Science
Languages : en
Pages : 498

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Book Description
Vision is the most important sense in higher mammals. The retina is the first step in visual processing and the window to the brain. It is not surprising that problems arising in the retina lead to moderate to severe visual impairments. We offer here a collection of reviews as well as original papers dealing with various aspects of retinal function as well as dysfunction. New approaches in retinal research are described, such as the expression and localization of the endocannabinoid system in the normal retina and the role of cannabinoid receptors that could offer new avenues of research in the development of potential treatments for retinal diseases. Moreover, new insights are offered in advancing knowledge towards the prevention and cure of visual pathologies, mainly AMD, RP, and diabetic retinopathy.

Neurodegeneration and Neuroprotection in Retinal Disease

Neurodegeneration and Neuroprotection in Retinal Disease PDF Author: Giovanni Casini
Publisher: Frontiers Media SA
ISBN: 2889637409
Category :
Languages : en
Pages : 159

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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Ocular Neuroprotection

Ocular Neuroprotection PDF Author: Leonard Levin
Publisher: CRC Press
ISBN: 0824756134
Category : Medical
Languages : en
Pages : 336

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Book Description
Ocular neuroprotection is aimed at protecting the death of photoreceptors, retinal ganglion, or other important neurons in cases of disease or trauma. Levin (ophthalmology and neurology, U. of Wisconsin at Madison, US) and Di Polo (pathology and cell biology, U. of Montreal, Canada) present 18 chapt.

Neurodegeneration and Neuroprotection in Retinal Disease, Volume II

Neurodegeneration and Neuroprotection in Retinal Disease, Volume II PDF Author: Giovanni Casini
Publisher: Frontiers Media SA
ISBN: 2832501400
Category : Science
Languages : en
Pages : 127

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Book Description


Glaucoma: An Open-Window to Neurodegeneration and Neuroprotection

Glaucoma: An Open-Window to Neurodegeneration and Neuroprotection PDF Author: Carlo Nucci
Publisher: Newnes
ISBN: 0080932800
Category : Medical
Languages : en
Pages : 639

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Book Description
Glaucoma is one of the main causes of blindness throughout the world. It is characterized by death of the retinal ganglion cells, which is associated with loss of the axons making up the optic nerve. Recent studies have demonstrated support for the classification of glaucoma as a degenerative disease of the central nervous system (CNS), leading researchers to look at identifying neuroprotection strategies for the treatment of this disease, like those used for other degenerative diseases of the CNS. This book will provide an in-depth examination of the most recent findings regarding glaucoma, including risk factors, diagnosis, clinical monitoring, treatment, and above all, the need for treatment based on the concept of neuroprotection. A large part of the book is devoted to research related to this new approach to the treatment of glaucoma. - Describes the most recent developments on neuroprotection of the optic nerve, including experimental models now used and clinical protocols - Discusses new strategies for the prevention of neuronal injury in glaucoma patients - Focuses on evidence-based risk factors, innovative diagnostic aspects and advanced medical/surgical treatment of glaucoma

Retinal Degenerative Diseases

Retinal Degenerative Diseases PDF Author: Matthew M. LaVail
Publisher: Springer Science & Business Media
ISBN: 1461406315
Category : Medical
Languages : en
Pages : 867

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Book Description
This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.

Neuroprotective Effects of Phytochemicals in Neurological Disorders

Neuroprotective Effects of Phytochemicals in Neurological Disorders PDF Author: Tahira Farooqui
Publisher: John Wiley & Sons
ISBN: 1119155142
Category : Medical
Languages : en
Pages : 662

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Book Description
Phytochemicals are naturally occurring bioactive compounds found in edible fruits, plants, vegetables, and herbs. Unlike vitamins and minerals, phytochemicals are not needed for the maintenance of cell viability, but they play a vital role in protecting neural cells from inflammation and oxidative stress associated with normal aging and acute and chronic age-related brain diseases. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the advances in our understanding of the potential neuroprotective benefits that these naturally occurring chemicals contain. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the role that a number of plant-based chemical compounds play in a wide variety of neurological disorders. Chapters explore the impact of phytochemicals on neurotraumatic disorders, such as stroke and spinal cord injury, alongside neurodegenerative diseases such as Alzheimer's and Parkinson's Disease, as well as neuropsychiatric disorders such as depression and schizophrenia. The chapters and sections of this book provide the reader with a big picture view of this field of research. Neuroprotective Effects of Phytochemicals in Neurological Disorders aims to present readers with a comprehensive and cutting edge look at the effects of phytochemicals on the brain and neurological disorders in a manner useful to researchers, neuroscientists, clinical nutritionists, and physicians.

Neurodegenerative Diseases

Neurodegenerative Diseases PDF Author: Shamim I. Ahmad
Publisher: Springer Science & Business Media
ISBN: 1461406536
Category : Medical
Languages : en
Pages : 421

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Book Description
The editor of this volume, having research interests in the field of ROS production and the damage to cellular systems, has identified a number of enzymes showing ·OH scavenging activities details of which are anticipated to be published in the near future as confirmatory experiments are awaited. It is hoped that the information presented in this book on NDs will stimulate both expert and novice researchers in the field with excellent overviews of the current status of research and pointers to future research goals. Clinicians, nurses as well as families and caregivers should also benefit from the material presented in handling and treating their specialised cases. Also the insights gained should be valuable for further understanding of the diseases at molecular levels and should lead to development of new biomarkers, novel diagnostic tools and more effective therapeutic drugs to treat the clinical problems raised by these devastating diseases.

Alzheimer’s Disease

Alzheimer’s Disease PDF Author: Ralph W. Richter
Publisher: Springer Science & Business Media
ISBN: 1592596614
Category : Medical
Languages : en
Pages : 577

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Book Description
Alzheimer’s disease (AD) is a devastating and dehumanizing illness affecting increasingly large numbers of elderly and even middle-aged persons in a worldwide epidemic. Alzheimer’s Disease: A Physician’s Guide to Practical Management was written by selected clinicians and scientists who represent some of the world’s leading centers of excellence in AD research. The editors are proud and grateful for their profound contributions. This book is particularly designed to assist physicians and other health-care professionals in the evaluation, assessment, and treatment of individuals with AD. At the same time, by illuminating the basic scientific background, we hope to provide state-of-the art information about the disease and possible future therapeutic strategies. The recent psychiatric treatment aspects of AD are also clearly presented. Because the early diagnosis of the dementia process is now considered of increasing importance, we focus particularly in several chapters on early changes and preclinical conditions, such as mild cognitive impairment and predementia AD.