Neuronal Ensemble Modeling and Analysis with Variable Order Markov Models

Neuronal Ensemble Modeling and Analysis with Variable Order Markov Models PDF Author: Antonio Giuliano Zippo
Publisher: Ledizioni
ISBN: 8895994574
Category : Mathematics
Languages : en
Pages : 158

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Book Description
Neuronal cells (neurons) mainly transmit signals by action potentials or spikes.Neuronal electrical activity is recorded from experimental animals bymicroelectrodesplaced in specific brain areas. These electrochemical fast phenomenaoccur as all-or-none events and can be analyzed as boolean sequences. Followingthis approach, several computational analyses reported most variable neuronalbehaviors expressed through a large variety of firing patterns [13]. Thesepatternshave been modeled as symbolic strings with a number of different techniques[23, 55]The results obtained with these methods come (i) from Ventrobasal ThalamicNuclei (VB) and Somatosensory Cortex (SSI) in Chronic Pain Animals (CPAs), (ii) from Primary Visual (V1) and (SSI) in rat Cortices and, finally, (iii) fromIL human Thalamus Nuclei in patients suffering from states of disorderedconsciousnesslike Persistent Vegetative State (PVS) and Minimum Conscious State(MCS).

Non-overlapping Domain Decomposition Methods for Three-dimensional Cardiac Reaction-diffusion Models and Applications

Non-overlapping Domain Decomposition Methods for Three-dimensional Cardiac Reaction-diffusion Models and Applications PDF Author: Stefano Zampini
Publisher: Ledizioni
ISBN: 8895994663
Category : Mathematics
Languages : en
Pages : 269

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Book Description
Recent advances in biotechnology and the availability of ever more powerful computers have led to the formulation of increasingly complex models at all levels of life sciences, in particular of cardiac electrophysiology. Multiscale modeling of the bioelectric activity of the heart, taking into account macroscopic (fiber architecture and anisotropy) and microscopic (cellular) features of the tissue, aim to develop predictive tools for future drug design and patient-specific therapies, using detailed and efficient three-dimensional solvers for the governing equations of tissue electrophysiology.

On Some Axiomatic Extensions of the Monoidal T-Norm Based Logic Mtl

On Some Axiomatic Extensions of the Monoidal T-Norm Based Logic Mtl PDF Author: Matteo Bianchi
Publisher: Ledizioni
ISBN: 8895994566
Category : Mathematics
Languages : en
Pages : 169

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Book Description
The scientific area this thesis belongs to is many-valued logics: this meanslogics in which, from the semantical point of view, we have "intermediate"truth-values, between 0 and 1 (which in turns are designated to represent, respectively, the "false" and the "true").The classical logic (propositional, for simplicity) is based on the fact thatevery statement is true or false: this is reflected by the excluded middle law, that is a theorem of this logic. However, there are many reasons that suggestto reject this law: for example, intuitionistic logic does not satisfy it, sincethis logic reflects a "constructive" conception of mathematics (see [Hey71, Tro69]).

Stochastic Methods in Cancer Research. Applications to Genomics and Angiogenesis

Stochastic Methods in Cancer Research. Applications to Genomics and Angiogenesis PDF Author: Paola M. V. Rancoita
Publisher: Ledizioni
ISBN: 8895994582
Category : Mathematics
Languages : en
Pages : 301

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Book Description
In this thesis, I study three stochastic methods that can be applied for the analysis of data in cancer research and, in particular, to cancer genomic data and to images of angiogenic processes. Cancer is a multistep process where the accumulation of genomic lesions alters cell biology. The latter is under control of several pathways and thus, cancer can arise via different mechanisms affecting different pathways. Due to the general complexity of this disease and the different types of tumors, the efforts of cancer research cover several research areas such as, for example, immunology, genetics, cell biology, angiogenesis.

On Quasiconvex Conditional Maps. Duality Results and Applications to Finance

On Quasiconvex Conditional Maps. Duality Results and Applications to Finance PDF Author: Marco Maggis
Publisher: Ledizioni
ISBN: 8895994590
Category : Mathematics
Languages : en
Pages : 143

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Book Description


Dynamic Neuroscience

Dynamic Neuroscience PDF Author: Zhe Chen
Publisher: Springer
ISBN: 3319719769
Category : Technology & Engineering
Languages : en
Pages : 327

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Book Description
This book shows how to develop efficient quantitative methods to characterize neural data and extra information that reveals underlying dynamics and neurophysiological mechanisms. Written by active experts in the field, it contains an exchange of innovative ideas among researchers at both computational and experimental ends, as well as those at the interface. Authors discuss research challenges and new directions in emerging areas with two goals in mind: to collect recent advances in statistics, signal processing, modeling, and control methods in neuroscience; and to welcome and foster innovative or cross-disciplinary ideas along this line of research and discuss important research issues in neural data analysis. Making use of both tutorial and review materials, this book is written for neural, electrical, and biomedical engineers; computational neuroscientists; statisticians; computer scientists; and clinical engineers.

Global COVID-19 Research and Modeling

Global COVID-19 Research and Modeling PDF Author: Longbing Cao
Publisher: Springer Nature
ISBN: 9819999154
Category :
Languages : en
Pages : 409

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Book Description


Metastable Dynamics of Neural Ensembles

Metastable Dynamics of Neural Ensembles PDF Author: Emili Balaguer-Ballester
Publisher: Frontiers Media SA
ISBN: 2889454371
Category :
Languages : en
Pages : 152

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Book Description
A classical view of neural computation is that it can be characterized in terms of convergence to attractor states or sequential transitions among states in a noisy background. After over three decades, is this still a valid model of how brain dynamics implements cognition? This book provides a comprehensive collection of recent theoretical and experimental contributions addressing the question of stable versus transient neural population dynamics from complementary angles. These studies showcase recent efforts for designing a framework that encompasses the multiple facets of metastability in neural responses, one of the most exciting topics currently in systems and computational neuroscience.

Stochastic Neuron Models

Stochastic Neuron Models PDF Author: Priscilla E. Greenwood
Publisher: Springer
ISBN: 3319269119
Category : Mathematics
Languages : en
Pages : 75

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Book Description
This book describes a large number of open problems in the theory of stochastic neural systems, with the aim of enticing probabilists to work on them. This includes problems arising from stochastic models of individual neurons as well as those arising from stochastic models of the activities of small and large networks of interconnected neurons. The necessary neuroscience background to these problems is outlined within the text, so readers can grasp the context in which they arise. This book will be useful for graduate students and instructors providing material and references for applying probability to stochastic neuron modeling. Methods and results are presented, but the emphasis is on questions where additional stochastic analysis may contribute neuroscience insight. An extensive bibliography is included. Dr. Priscilla E. Greenwood is a Professor Emerita in the Department of Mathematics at the University of British Columbia. Dr. Lawrence M. Ward is a Professor in the Department of Psychology and the Brain Research Centre at the University of British Columbia.

Ensemble Modeling

Ensemble Modeling PDF Author: Gelfand
Publisher: CRC Press
ISBN: 9780824771805
Category : Mathematics
Languages : en
Pages : 304

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Book Description
The overall purpose of this book is to examine several broad questions in general systems theory and to suggest areas of application for the approach used. This volume offers a unique statistical approach, utilizing populations of models in the analysis of complex systems. With this novel method, called Ensemble Modeling, the book enables researchers to infer the behavioural properties of a system from small scale details.