Neuronal Cell Death and Repair PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Neuronal Cell Death and Repair PDF full book. Access full book title Neuronal Cell Death and Repair by A. Claudio Cuello. Download full books in PDF and EPUB format.
Author: A. Claudio Cuello
Publisher:
ISBN: 1483290263
Category : Brain
Languages : en
Pages : 333
Get Book Here
Book Description
This text deals with concepts and experimental possibilities which could not have been anticipated 10 years ago. Recent hard evidence that neuronal cells in the central nervous system possess a capability for recovery after trauma well beyond that previously recognized poses many fundamental and secondary questions. For example: is there a programmed cell death phenomenon in the mature brain? Under what circumstances do neurotransmitters promote trophic responses in neurons or provoke cell death? How might environmental or toxic molecules be responsible for specific neuronal damage? conference on which this volume is partly based. Various additional invited papers are contained in this work on neuronal cell death and repair.
Author: Laura Lossi
Publisher: Humana Press
ISBN: 9781493921515
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
This volume represents a valuable and readily reproducible collection of established and emerging techniques for neuronal cell death research. Conveniently divided into four parts, sections cover a series of techniques for the molecular, structural, functional and genomic characterization of dying neurons, a number of protocols that are of primary interest in neuropathology and in experimental neuropathology, a series of gene engineering techniques to obtain and manipulate neuronal stem cells and progenitors, to prepare HSV-1 vectors for the gene therapy, and to CNS transplantation of bone marrow stem cells, and finally, some very interesting protocols for the study of cell death in non-mammalian models. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Neuronal Cell Death: Methods and Protocols seeks to serve a large audience of scientists that are currently active in the field or are willing to enter such an exciting and still expanding area of neurobiology.
Author: A. Claudio Cuello
Publisher:
ISBN: 1483290263
Category : Brain
Languages : en
Pages : 333
Get Book Here
Book Description
This text deals with concepts and experimental possibilities which could not have been anticipated 10 years ago. Recent hard evidence that neuronal cells in the central nervous system possess a capability for recovery after trauma well beyond that previously recognized poses many fundamental and secondary questions. For example: is there a programmed cell death phenomenon in the mature brain? Under what circumstances do neurotransmitters promote trophic responses in neurons or provoke cell death? How might environmental or toxic molecules be responsible for specific neuronal damage? conference on which this volume is partly based. Various additional invited papers are contained in this work on neuronal cell death and repair.
Author: Robert Vink
Publisher: University of Adelaide Press
ISBN: 0987073052
Category : Medical
Languages : en
Pages : 354
Get Book Here
Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author: Daniel Laskowitz
Publisher: CRC Press
ISBN: 1498766579
Category : Medical
Languages : en
Pages : 388
Get Book Here
Book Description
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Author: Agata Copani
Publisher: Springer Science & Business Media
ISBN: 0387293906
Category : Medical
Languages : en
Pages : 110
Get Book Here
Book Description
Cell-Cycle Mechanisms and Neuronal Cell Death examines the role of cell cycle activation in the molecular mechanisms leading to neuronal degeneration. Leading Authors discuss this topic in relation to the major neurological disorders, including Alzheimer’s disease, stroke and epilepsy. This book serves to gain new insights into the molecular determinants of neuronal death and to establish new targets for therapeutic intervention.
Author: Irwin B. Levitan
Publisher: Oxford University Press, USA
ISBN: 9780195145236
Category : Molecular neurobiology
Languages : en
Pages : 640
Get Book Here
Book Description
Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.
Author: C.E. Henderson
Publisher: Springer Science & Business Media
ISBN: 3662043335
Category : Medical
Languages : en
Pages : 162
Get Book Here
Book Description
Four chapters represent the intense current effort to understand the way in which the mitochondrion controls the activation of the final stages of cell death. Another four articles attack the problem from the other side. How do specific insults in particular human or mouse neuro-degenerative diseases translate into mechanisms that will not only allow us to better understand what is happening in these patients but also, with luck, allow for development of more efficient and specific drugs in the future? Firstly, the concept of a central common cell death pathway, originally derived from studies on the nematode, has been an outstanding productive paradigm in bringing together different strands of research. Secondly, truly striking links have been made between results obtained in the culture dish (or even cell-free systems) and the diseased human brain.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309172195
Category : Social Science
Languages : en
Pages : 285
Get Book Here
Book Description
Possible new breakthroughs in understanding the aging mind that can be used to benefit older people are now emerging from research. This volume identifies the key scientific advances and the opportunities they bring. For example, science has learned that among older adults who do not suffer from Alzheimer's disease or other dementias, cognitive decline may depend less on loss of brain cells than on changes in the health of neurons and neural networks. Research on the processes that maintain neural health shows promise of revealing new ways to promote cognitive functioning in older people. Research is also showing how cognitive functioning depends on the conjunction of biology and culture. The ways older people adapt to changes in their nervous systems, and perhaps the changes themselves, are shaped by past life experiences, present living situations, changing motives, cultural expectations, and emerging technology, as well as by their physical health status and sensory-motor capabilities. Improved understanding of how physical and contextual factors interact can help explain why some cognitive functions are impaired in aging while others are spared and why cognitive capability is impaired in some older adults and spared in others. On the basis of these exciting findings, the report makes specific recommends that the U.S. government support three major new initiatives as the next steps for research.
Author: Irene Ceballos-Picot
Publisher: Springer Science & Business Media
ISBN: 3662225166
Category : Medical
Languages : en
Pages : 391
Get Book Here
Book Description
This book examines current knowledge and recent advances in the study of fundamental processes involved in neuronal death, particularly oxidative stress as a causal agent or risk factor. The author presents discussion of oxidative stress in neuronal apoptosis and its role in the neuropathogenesis of age-related neurodegenerative diseases exemplified by Alzheimer's disease, Parkinson's disease and Amyotrophic Lateral Sclerosis.
Author: A. Claudio Cuello
Publisher: Elsevier Science Limited
ISBN: 9780444814708
Category : Science
Languages : en
Pages : 317
Get Book Here
Book Description
This text deals with concepts and experimental possibilities which could not have been anticipated 10 years ago. Recent hard evidence that neuronal cells in the central nervous system possess a capability for recovery after trauma well beyond that previously recognized poses many fundamental and secondary questions. For example: is there a programmed cell death phenomenon in the mature brain? Under what circumstances do neurotransmitters promote trophic responses in neurons or provoke cell death? How might environmental or toxic molecules be responsible for specific neuronal damage? conference on which this volume is partly based. Various additional invited papers are contained in this work on neuronal cell death and repair.
