Author: Frederik Barkhof
Publisher: Springer Science & Business Media
ISBN: 3642008186
Category : Medical
Languages : en
Pages : 295
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Book Description
This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the various causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible. After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key findings in patients with dementias. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book will prove an invaluable resource.
Author: Jiu Chen
Publisher: Frontiers Media SA
ISBN: 2832542662
Category : Science
Languages : en
Pages : 358
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Book Description
Subjective cognitive decline (SCD) with self-reported concerns and mild cognitive impairment (MCI) are well-established to be at increased risk of developing Alzheimer’s disease (AD) dementia and a clinical continuum of dementia progression as a spectrum of AD. AD may develop from SCD to MCI (early MCI and late MCI) and eventually to AD. Nevertheless, until recently little was known about their pathophysiology associated with cognitive-behavioral syndrome. Although for researchers, scientists and clinicians, the pathophysiology of AD spectrum is an intriguing issue, delineating it in a clear way is far from easy. Taken together, in-depth understanding of neuroimaging-based pathology behind cognitive impairments across AD spectrum may help to develop new strategy for the early diagnosis and treatment of AD. Neuroimaging has been thought to potentially reveal the pathological mechanisms of AD progression. Individuals across AD spectrum are often associated with anatomical and functional brain alterations and cognitive impairment, most of the pathophysiology will focus primarily on the brain. To investigate brain structures and functions associated with cognition, neuroimaging will be the most appropriate tool.
Author: Heiko Braak
Publisher: Springer
ISBN: 3319126792
Category : Medical
Languages : en
Pages : 168
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Book Description
As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail
Author: Bradford Dickerson
Publisher: Oxford University Press
ISBN: 0199928460
Category : Medical
Languages : en
Pages : 705
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Book Description
Dementia: Comprehensive Principles and Practice is a clinically-oriented book designed for clinicians, scientists, and other health professionals involved in the diagnosis, management, and investigation of disease states causing dementia. A "who's who" of internationally-recognized experts contribute chapters emphasizing a multidisciplinary approach to understanding dementia. The organization of the book takes an integrative approach by providing three major sections that (1) establish the neuroanatomical and cognitive framework underlying disorders of cognition, (2) provide fundamental as well as cutting-edge material covering specific diseases associated with dementia, and (3) discuss approaches to the diagnosis and treatment of dementing illnesses.
Author: Velandai Srikanth
Publisher: Academic Press
ISBN: 0128096942
Category : Medical
Languages : en
Pages : 322
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Book Description
Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology. - Presents a comprehensive overview that details the relationship between diabetes, dementia and the future of medicine and therapeutics - Written for researchers and clinicians in neurology, neuroscience, geriatric medicine and endocrinology - Includes topics ranging from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment, prevention strategies and therapeutic applications
Author: Robert Howard
Publisher: Routledge
ISBN:
Category : Medical
Languages : en
Pages : 296
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Book Description
Schizophrenia, which starts in middle age or late life, has been described as 'the darkest area of psychiatry.' It is certainly controversial, with much disagreement about cut-off ages, diagnostic criteria and nomenclature. The contributors to this unique and very important book represent views from Europe and North America as well as Australia, Japan, and Nepal; they come from backgrounds of clinical practice and research. The contributors and editors were motivated by common aims: to review current international knowledge about late onset schizophrenia, to debate issues of heterogenity, gender, brain maturation and aging, putative structural and functional cerebral substrates for psychosis, to reach consensus on diagnosis and terminology, and to future research directions. The resulting book is an unqualified success which as well as being invaluable in old age psychiatry, sheds light on all aspects of schizophrenia treatment and research.
Author: Judith Pratt
Publisher: Springer
ISBN: 3319996428
Category : Medical
Languages : en
Pages : 431
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Book Description
This volume addresses one of the Holy Grails in Psychiatry, namely the evidence for and potential to adopt ‘Biomarkers’ for prevention, diagnosis, and treatment responses in mental health conditions. It meshes together state of the art research from international renowned pre-clinical and clinical scientists to illustrate how the fields of anxiety disorders, depression, psychotic disorders, and autism spectrum disorder have advanced in recent years.
Author: Charlotte E. Teunissen
Publisher: Humana
ISBN: 9781071613214
Category : Medical
Languages : en
Pages : 236
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Book Description
This volume covers the latest methods used in clinical neurochemistry laboratories for both clinical practice and research. Chapters in this book discuss topics such as techniques for cerebrospinal fluid (CSF) collection, pre-analytical processing, and basic CSF analysis; an examination of biomarkers including ELISA and automated immunochemical assays for amyloid and tau markers for Alzheimer’s disease; the analysis of neurofilaments by digital ELISA; and an example of successful novel immunoassay development. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Cerebrospinal Fluid Biomarkers is a valuable resource for clinicians and researchers to use in CSF labs and CSF courses.
Author: Cynthia H. Y. Fu
Publisher: CRC Press
ISBN: 9781841842295
Category : Medical
Languages : en
Pages : 288
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Book Description
New neuroimaging techniques are developing at a break neck pace-every academic journal contains glossy pictures of brain activity corresponding to a particular task emblazoned in glorious technicolor. Discoveries about brain function in psychiatric disorders have been made at an equally rapid rate. However, most books on the subject have been written from a technical point of view. An introductory, easy-to-read guide, Neuroimaging in Psychiatry provides an overview and the clinical relevance of the latest neuroimaging findings. With contributions from an international panel of experts, this book reviews current findings from neuroimaging in schizophrenia, obsessive-compulsive disorder, depression, eating disorders, psychopathy, aging, and drug addiction. Chapter authors explore innovative and imaginative uses of neuro imaging technology, implications for our understanding of these disorders, and their impact on clinical practice. The book gives you a general overview of the main techniques to help you successfully complete a neuroimaging project.
Author: Christopher M. Filley
Publisher: Cambridge University Press
ISBN: 1107035414
Category : Medical
Languages : en
Pages : 231
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Book Description
Presenting the novel concept of white matter dementia, this unique book offers hope for a better understanding and treatment of dementia.
