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Author: Detlev Ganten
Publisher: Springer Science & Business Media
ISBN: 3642727387
Category : Medical
Languages : en
Pages : 335
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Book Description
With contributions by numerous experts
Author: Detlev Ganten
Publisher: Springer Science & Business Media
ISBN: 3642727387
Category : Medical
Languages : en
Pages : 335
Get Book Here
Book Description
With contributions by numerous experts
Author: Dennis S. Charney
Publisher: Oxford University Press
ISBN: 019068142X
Category : Medical
Languages : en
Pages : 1025
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Book Description
In the years following publication of the DSM-5(R), the field of psychiatry has seen vigorous debate between the DSM's more traditional, diagnosis-oriented approach and the NIMH's more biological, dimension-based RDoC (research domain criteria) approach. Charney & Nestler's Neurobiology of Mental Illness is an authoritative foundation for translating information from the laboratory to clinical treatment, and its fifth edition extends beyond this reference function to acknowledge and examine the controversies, different camps, and thoughts on the future of psychiatric diagnosis. In this wider context, this book provides information from numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. Sections and chapters are edited and authored by experts at the top of their fields. No other book distills the basic science and underpinnings of mental disorders-and highlights practical clinical significance-to the scope and breadth of this classic text. In this edition, Section 1, which reviews the methods used to examine the biological basis of mental illness in animal and cell models and in humans, has been expanded to reflect critically important technical advances in complex genetics (including powerful sequencing technologies and related bioinformatics), epigenetics, stem cell biology, optogenetics, neural circuit functioning, cognitive neuroscience, and brain imaging. This range of established and emerging methodologies offer groundbreaking advances in our ability to study the brain as well as unique opportunities for the translation of preclinical and clinical research into badly needed breakthroughs in our therapeutic toolkit. Sections 2 through 7 cover the neurobiology and genetics of major psychiatric disorders: psychoses (including bipolar disorder), mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood onset. Also covered within these sections is a summary of current therapeutic approaches for these illnesses as well as the ways in which research advances are now guiding the search for new treatments. Each of these parts has been augmented in several different areas as a reflection of research progress. The last section, Section 8, reconfigured in this new edition, now focuses on diagnostic schemes for mental illness. This includes an overview of the unique challenges that remain in diagnosing these disorders given our still limited knowledge of disease etiology and pathophysiology. The section then provides reviews of DSM-5(R), which forms the basis of psychiatric diagnosis in the United States for all clinical work, and of RDoC, which provides an alternative perspective on diagnosis in heavy use in the research community. Also included are chapters on future efforts toward precision and computational psychiatry, which promise to someday align diagnosis with underlying biological abnormalities.
Author: George Fink
Publisher: Academic Press
ISBN: 0123750970
Category : Medical
Languages : en
Pages : 895
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Book Description
Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.
Author: Argyris Stringaris
Publisher: OUP Oxford
ISBN: 0191662062
Category : Medical
Languages : en
Pages : 191
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Book Description
A practical guide to understanding and treating children and adolescents prone to extreme levels of angry outbursts, Disruptive Mood: Irritability in Children and Adolescents is based on the very latest research and theory. Providing both a clinical and scientific perspective on irritability in children, this book is a timely look at recent developments in the field. Abnormal states of anger are a common reason for referral to child health services, and cause concern in clinics, schools, and families. Misdiagnosis and treatment can stem from a lack of understanding of the mechanisms involved in high levels of anger in children, and Disruptive Mood: Irritability in Children and Adolescents provides clear guidance on the development of abnormal states of anger, their consequences for later development, and how to assess and make differential diagnoses between them. A useful resource for clinical practice, this book is concise and accessible, and offers tools for evaluating treatments. Disruptive Mood: Irritability in Children and Adolescents is designed for practitioners involved in child and adolescent mental health and education and researchers who need an introduction to this complex field.
Author: Roger S. McIntyre
Publisher: Cambridge University Press
ISBN: 1316368572
Category : Medical
Languages : en
Pages : 385
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Book Description
Major depressive disorder (MDD) is the leading cause of disability globally in both developed and developing nations. The staggering economic costs attributable to MDD are largely a consequence of impairment in role function. Evidence indicates that disturbance in the domain of cognitive function in individuals with MDD is the principal determinant of health outcome. This is the first book to comprehensively explore the domain of cognition in MDD. The literature describing cognitive dysfunction is reviewed with particular focus on clinical determinants, pathophysiology and causative factors. The patient subpopulations most susceptible are defined. A summary of contemporary assessment tools for research and clinical purposes is provided. Multimodality treatments and prevention strategies are described. This book is an invaluable resource for psychiatrists, neuropsychologists and other members of the mental health team, as well as for policy makers, vocation rehabilitation experts, disability providers and other stakeholders interested in improving health outcomes in MDD.
Author: Robert J. DeRubeis
Publisher: Oxford University Press
ISBN: 0199973962
Category : Psychology
Languages : en
Pages : 537
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Book Description
The most comprehensive volume of its kind, The Oxford Handbook of Mood Disorders provides detailed coverage of the characterization, understanding, and treatment of mood disorders. Chapters are written by the world's leading experts in their respective areas. The Handbook provides coverage of unipolar depression, bipolar disorder, and variants of these disorders. Current approaches to classifying the mood disorders are reviewed and contemporary controversies are placed in historical context. Chapter authors offer a variety of approaches to understanding the heterogeneity of the experiences of those who meet criteria for mood disorders, both within and across cultures. The role of genetic and environmental risk factors as well as premorbid personality and cognitive processes in the development of mood pathology are detailed. Interpersonal, neurobiological, and psychological factors also receive detailed consideration. The volume reviews mood disorders in special populations (e.g., postpartum and seasonal mood disorders) as well as common comorbidities (e.g., anxiety, substance use disorders). Somatic and psychosocial treatment approaches receive in-depth coverage with chapters that describe and review empirical evidence regarding each of the most influential treatment approaches. The depth and breadth offered by this Handbook make it an invaluable resource for clinicians and researchers, as well as scholars and students.
Author: Michael Wilkinson
Publisher: Cambridge University Press
ISBN: 1316645193
Category : Medical
Languages : en
Pages : 207
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Book Description
A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.
Author: Detlev Ganten
Publisher: Springer Science & Business Media
ISBN: 3642758371
Category : Medical
Languages : en
Pages : 295
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Book Description
Latest issue in the CURRENT TOPICS IN NEUROENDOCRINOLOGY se- ries which has been gaining a great deal of reputation as a primary source for reviews in neuroendocrinology and related areas in the past few years.
Author: Simon Wessely
Publisher: Oxford University Press, USA
ISBN: 9780192630469
Category : Medical
Languages : en
Pages : 428
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Book Description
Chronic Fatigue Syndrome (also known as M.E) is an illness characterized by the symptom of chronic and severe fatigue, in the absence of an alternative medical condition. It has been the subject of intense media debate over recent years. Such interest has been partially due to the polarization of professional and scientific opinion concerning the topic - what is it, and what causes it? Chonic Fatigue and its syndromes presents an objective and comprehensive review of the problem ofchronic fatigue, mixing medical, psychological, social, and historical perspectives. It begins by considering the nature of fatigue, and its physical and psychological origins. The book then introduces the subject of CFS, tracing its historical origins, before considering the epidemiology, and the various aetiological theories for modern forms of the condition - viral, immunological, psychologica, psychiatric, and neurological. The book concludes with a clinical section that gives a step by step guide to the assessment and treatment of CFS. Throughout, the authors argue that chronic fatigue and its various syndromes cannot easily be pigeonholed into either physical or psychological categories, and that the ambiguous nature of the illness actually provides us with a valuable chance to explore contemporary attitutes to sickness and health, one not offered by better defined or classified disorders.
Author: Francis J. P. Ebling
Publisher: Springer Nature
ISBN: 3030556433
Category : Medical
Languages : en
Pages : 253
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Book Description
This book explores how daily and seasonal rhythmicity is generated, how these rhythms are synchronised by our environment, and how they regulate the neuroendocrine systems that impact our physiology and behaviour. The constraints of surviving in a seasonal environment have shaped human evolution and migration, have shaped our societies and cultures, and continue to influence our everyday lives, health and wellbeing. Identifying the mechanisms whereby seasonal rhythmicity is generated and regulates the brain and body is not only important for understanding the natural world and relevant to animal production, it also offers many insights into the human condition. Each chapter is written by an international expert in the field of chronobiology. A historical perspective on how research into photoperiodism and rhythmicity progressed is initially provided, but the main focus of this book is on the remarkable studies in the last few decades that have unravelled the molecular and cellular machinery underpinning circadian and circannual timing. Topics covered include the role of melatonin in communicating seasonal information to the brain and pituitary gland, the neuroanatomical pathways in mammals, birds and fish by which changes in photoperiod reach the hypothalamus, the role of glial cells (tanycytes) and thyroid hormone in seasonal rhythmicity, neuroplasticity across seasons, effects of changing day length on mood, regulation of “clock“ gene expression, and the role of the suprachiasmatic nucleus. This book will appeal to all students and researchers who wish to learn about current and past research on daily and seasonal rhythmicity. This is the tenth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.
