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Author: Richard T. Robertson
Publisher: Academic Press
ISBN: 1483266400
Category : Science
Languages : en
Pages : 462
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Book Description
Neuroanatomical Research Techniques discusses developments in major neuroanatomical research techniques. The book is organized into four parts. Part I deals generally with the preparation and study of brain tissue. It includes a chapter on the microscope, discussing optical magnification, limitations of microscopy, and optical contrasting methods. Other chapters summarize basic techniques for tissue preparation and sectioning; present guidelines for a number of standard, but essential, staining procedures; and present sophisticated and contemporary computer techniques that are proving to be invaluable as neuroanatomy evolves from a qualitative to a quantitative discipline. Part II deals with techniques often used for the study of normal tissue. These include the Golgi method, fluorescence histochemistry, techniques for staining single neurons, and the use of the electron microscope. Part III presents techniques for studying intrinsic connections of the nervous system. These include techniques for silver impregnation of degenerating fibers; autoradiographic technique for studying axonal projections; and somatopetal movement of horseradish peroxidase as a tool for studying connections and neuron morphology. Part IV discusses the interpretation of results from neuroanatomical research techniques and presents examples of the applications of neuroanatomical methods to major problems in physiological psychology.
Author: Richard T. Robertson
Publisher: Academic Press
ISBN: 1483266400
Category : Science
Languages : en
Pages : 462
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Book Description
Neuroanatomical Research Techniques discusses developments in major neuroanatomical research techniques. The book is organized into four parts. Part I deals generally with the preparation and study of brain tissue. It includes a chapter on the microscope, discussing optical magnification, limitations of microscopy, and optical contrasting methods. Other chapters summarize basic techniques for tissue preparation and sectioning; present guidelines for a number of standard, but essential, staining procedures; and present sophisticated and contemporary computer techniques that are proving to be invaluable as neuroanatomy evolves from a qualitative to a quantitative discipline. Part II deals with techniques often used for the study of normal tissue. These include the Golgi method, fluorescence histochemistry, techniques for staining single neurons, and the use of the electron microscope. Part III presents techniques for studying intrinsic connections of the nervous system. These include techniques for silver impregnation of degenerating fibers; autoradiographic technique for studying axonal projections; and somatopetal movement of horseradish peroxidase as a tool for studying connections and neuron morphology. Part IV discusses the interpretation of results from neuroanatomical research techniques and presents examples of the applications of neuroanatomical methods to major problems in physiological psychology.
Author: N.J. Strausfeld
Publisher: Springer Science & Business Media
ISBN: 1461260183
Category : Science
Languages : en
Pages : 517
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Book Description
Most neurobiological research is performed on vertebrates, and it is only natural that most texts describing neuroanatomical methods refer almost exclusively to this Phylum. Nevertheless, in recent years insects have been studied intensively and are becoming even more popular in some areas of research. They have advantages over vertebrates with respect to studying genetics of neuronal development and with respect to studying many aspects of integration by uniquely identifiable nerve cells. Insect central nervous system is characterized by its compactness and the rather large number of nerve cells in a structure so small. But despite their size, parts of the insect eNS bear structural comparisons with parts of vertebrate eNS. This applies particularly to the organization of the thoracic ganglia (and spinal cord), to the insect and vertebrate visual sys tems and, possibly, to parts of the olfactory neuropils. The neurons that make up these areas in insects are often large enough to be impaled by microelectrodes and can be injected with dyes. Added to advantages of using a small eNS, into which the sensory periphery is precisely mapped, are the many aspects of insect behaviour whose components can be quan titized and which may find both structural and functional correlates within clearly defined regions of neuropil. Together, these various features make the insect eNS a rewarding object for study. This volume is the first of two that describe both classic and recent methods for neuroanatomical research on insect eNS.
Author: C. Heym
Publisher: Springer Science & Business Media
ISBN: 3642680291
Category : Medical
Languages : en
Pages : 405
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Book Description
"Anatomy is the mother of physiology" - this statement was used to characterize the evolution of physiology from anato my as an independent science in the late nineteenth century. It had particular truth for neurophysiology, which started as functional neuroanatomy based on the observation of changes in behaviour after lesions of the nervous system both in ex perimental animals and in human patients. Today, anatomy may again be considered the mother of physiology; however, the meaning of this statement is rather different from that 100 years ago: The modem mother provides a dwelling for an increasing number of children endowed with new functional capabilities. This book provides a good illustration of such se mantic metamorphosis in the case of neuroanatomy. After a long period of little progress in either macroscopic neuroanatomy or neurohistology, during which the heritage of Cajal, Golgi, and others was developed and refined to yield a functional concept of the nervous system, the past two de cades have seen tremendous progress in methods applicable to the analysis of the nervous system. The new era was heralded by the introduction of the electron microscope to investigate the nervous system. This book is an impressive witness to the more recent developments.
Author: Laszlo Zaborszky
Publisher: Springer Science & Business Media
ISBN: 0387289429
Category : Medical
Languages : en
Pages : 703
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Book Description
The first two editions of this title had a tremendous impact in neuroscience. Between the Second edition in 1989 and today, there has been an explosion of information in the field, including advances in molecular techniques, such as genomics and proteomics, which have become increasing important in neuroscience. A renaissance in fluorescence has occurred, driven by the development of new probes, new microscopes, live imagers, and computer processing. The introduction of new markers has enormously stimulated the field, moving it from tissue culture to neurophysiology to functional MRI techniques.
Author: Giorgio A. Ascoli
Publisher: Springer Science & Business Media
ISBN: 1592592759
Category : Medical
Languages : en
Pages : 466
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Book Description
In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models.
Author: Moo K. Chung
Publisher: World Scientific
ISBN: 9814335436
Category : Computers
Languages : en
Pages : 424
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Book Description
Computational neuroanatomy is an emerging field that utilizes various non-invasive brain imaging modalities, such as MRI and DTI, in quantifying the spatiotemporal dynamics of the human brain structures in both normal and clinical populations. This discipline emerged about twenty years ago and has made substantial progress in the past decade. The main goals of this book are to provide an overview of various mathematical, statistical and computational methodologies used in the field to a wide range of researchers and students, and to address important yet technically challenging topics in further detail.
Author: Michael Petrides
Publisher: Academic Press
ISBN: 0124059317
Category : Psychology
Languages : en
Pages : 197
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Book Description
Many studies of the neural bases of language processes are now conducted with functional and structural neuroimaging. Research is often compromised because of difficulties in identifying the core structures in the face of the complex morphology of these regions of the brain. Although there are many books on the cognitive aspects of language and also on neurolinguistics and aphasiology, Neuroanatomy of Language Regions of the Human Brain is the first anatomical atlas that focuses on the core regions of the cerebral cortex involved in language processing. This atlas is a richly illustrated guide for scientists interested in the gross morphology of the sulci and gyri of the core language regions, in the cytoarchitecture of the relevant cortical areas, and in the connectivity of these areas. Data from diffusion MRI and resting-state connectivity are integrated iwth critical experimental anatomical data about homologous areas in the macaque monkey to provide the latest information on the connectivity of the language-relevant cortical areas of the brain. Although the anatomical connectivity data from studies on the macaque monkey provide the most detailed information, they are often neglected because of difficulties in interpreting the terminology used and in making the monkey-to-human comparison. This atlas helps investigators interpret this important source of information. Neuroanatomy of Language Regions of the Human Brain will assist investigators of the neural bases of language in increasing the anatomical sophistication of their research adn in evaluating studies of language and the brain. - Abundantly illustrated with photographs, 3-D MRI reconstructions, and sections to represent the morphology of the sulci and gyri in the frontal, temporal, and parietal regions involved in language processing - Photomicrographs showing the cytoarchitecture of cortical areas involved in language processing - Series of coronal, sagittal, and horizontal sections identifying the sulci and gyri to assist language investigators using structural and functional neuroimaging techniques - All images accompanied by brief commentaries to help users navigate the complexities of the anatomy - Integration of data from diffusion MRI and resting-state connectivity with critical experimental anatomical data on the connectivity of homologous areas in the macaque monkey
Author: Robin A. Hurley
Publisher: American Psychiatric Pub
ISBN: 1585628816
Category : Medical
Languages : en
Pages : 266
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Book Description
Windows to the Brain is the only book to synthesize neuroanatomical and imaging research as it pertains to selected neuropsychiatric diseases, containing all of the "Windows to the Brain" papers published from 1999-2006 in the Journal of Neuropsychiatry and Clinical Neurosciences. These reader-friendly summaries by more than sixty contributors present modern imaging techniques that assist in the diagnosis of neuropsychiatric illness, enhanced by easily understood color graphics of the neuroanatomical circuits of behavior, memory, and emotion. They provide a basic understanding of how to apply a variety of imaging techniques to the study of adult neuropsychiatric disease and how to use neuroimaging to assist in diagnostic work-ups for conditions ranging from sleep disorders to epilepsy to borderline personality. Integrated, color-coded graphics present functional anatomical information in a manner that promotes understanding and use in clinical practice, while the text encompasses a wide range of diseases and injuries across the adult lifespan. The book is organized into four sections that will help readers increase their appreciation of the wide range of research and clinical applications for imaging in neuropsychiatry: chapters on imaging techniques discuss underlying principles, strengths and weaknesses, and applications; chapters on specific diseases demonstrate a range of investigative techniques; anatomy/circuit chapters focus on particular brain structures or functional neuropsychiatric circuits; and final chapters present image-based approaches to understanding or selecting treatment options. Some of the applications described are: Use of fMRI in posttraumatic stress disorder to reveal the delicate balance between the structures of the emotion and memory tracks; Use of high-resolution MRI and nuclear imaging to distinguish between panic disorder and simple partial seizure disorder; Use of functional imaging studies to detect corticobasal degeneration, as a means of better understanding dementia; Use of newer imaging techniques in identifying progressive multifocal leukoencephalopathy, to enable more rapid and reliable tailoring of individual therapy for HIV; Use of functional neuroimaging in the study of fear, in order to better understand and treat anxiety-based psychiatric disorders; Use of neuroimaging studies in conversion disorder, showing implications for the disruption of selfhood in dissociative identity disorder and schizophrenia; Use of FDG-PET scans to look for predictors of treatment response in childhood-onset obsessive-compulsive disorder. Windows to the Brain can help bring less-experienced readers up to speed on advanced imaging and anatomical details that pertain to the modern practice of neuropsychiatry. It is must-reading for specialists in neuropsychiatry and cognitive/behavioral neurology, or for general psychiatrists with an interest in neuroimaging.
Author: Stanley Jacobson
Publisher: Springer Science & Business Media
ISBN: 0387709711
Category : Medical
Languages : en
Pages : 529
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Book Description
This book is designed to help prepare them by introducing many of the fundamentals of the nervous system. It represents the essentials of an upper level biology course on the central nervous system. It is not designed to be a clinical approach to the nervous system, but rather it approaches the nervous system from a basic science perspective that intertwines both structure and function as an organizing teaching and learning model.
Author: Adam Fisch MD
Publisher: Oxford University Press
ISBN: 0199708533
Category : Medical
Languages : en
Pages : 482
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Book Description
"If you can't draw it, you don't know it:" that was the rule of the late neuroanatomist William DeMyer, MD. Yet books do not encourage us to draw and redraw neuroanatomy. Neuroanatomy: Draw It to Know It teaches neuroanatomy through step-by-step instruction of how to draw neuroanatomical pathways and structures. Its instructive language is highly engaging. Users draw neuroanatomical structures and pathways in several steps so they are remembered and use mental and physical mnemonics to demonstrate difficult anatomical rotations and directional pathways. Anatomical pictures and radiographic images accompany the diagrams to clarify spatially challenging features; relevant synonyms are listed to avoid inter-text confusion; inconsistencies in the neuroanatomy literature are highlighted to mitigate frustration; and historical and current accounts of neuroanatomical systems are presented for perspective. Many neuroanatomy textbooks are great references, but fail to provide a working knowledge of neuroanatomy, and many neuroanatomy handbooks provide bedside pearls, but are too concise to be fully satisfactory. This instructional workbook teaches a comprehensive, but practical approach to neuroanatomy; it includes references where necessary but steers users toward key clinical features. Most importantly, Neuroanatomy: Draw It to Know It instructs the reader to draw and redraw the anatomy and teaches an active approach to learning.
