Neglected Tropical Diseases and Phytochemicals in Drug Discovery

Neglected Tropical Diseases and Phytochemicals in Drug Discovery PDF Author: Chukwuebuka Egbuna
Publisher: John Wiley & Sons
ISBN: 1119616603
Category : Science
Languages : en
Pages : 628

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Book Description
NEGLECTED TROPICAL DISEASES AND PHYTOCHEMICALS IN DRUG DISCOVERY Explore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. This book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals. The distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of: Thorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseases An exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasis Discussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicals Examinations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasis Perfect for medicinal chemists, drug developers, and research and development scientists, Neglected Tropical Diseases and Phytochemicals in Drug Discovery will also earn a place in the libraries of toxicologists and researchers in biology, chemistry, medicinal chemistry, ethnobotany, and bioinformatics seeking a one-stop resource for drug discovery for neglected tropical diseases.

Neglected Tropical Diseases and Phytochemicals in Drug Discovery

Neglected Tropical Diseases and Phytochemicals in Drug Discovery PDF Author: Chukwuebuka Egbuna
Publisher: John Wiley & Sons
ISBN: 1119616603
Category : Science
Languages : en
Pages : 628

Get Book Here

Book Description
NEGLECTED TROPICAL DISEASES AND PHYTOCHEMICALS IN DRUG DISCOVERY Explore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. This book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals. The distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of: Thorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseases An exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasis Discussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicals Examinations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasis Perfect for medicinal chemists, drug developers, and research and development scientists, Neglected Tropical Diseases and Phytochemicals in Drug Discovery will also earn a place in the libraries of toxicologists and researchers in biology, chemistry, medicinal chemistry, ethnobotany, and bioinformatics seeking a one-stop resource for drug discovery for neglected tropical diseases.

The Legal Aspects of Protective Services for Abused and Neglected Children

The Legal Aspects of Protective Services for Abused and Neglected Children PDF Author: Barbara A. Caulfield
Publisher:
ISBN:
Category : Abused children
Languages : en
Pages : 140

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Book Description


Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases

Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases PDF Author: Goutam Brahmachari
Publisher: Elsevier
ISBN: 0128157240
Category : Science
Languages : en
Pages : 461

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Book Description
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more. In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases. - Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery - Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases - Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases

Neglected Discovery

Neglected Discovery PDF Author: Jenia Iontcheva Turner
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Book Description
In recent decades, many states have expanded discovery in criminal cases. These reforms were designed to make the criminal process fairer and more efficient. The success of these changes, however, depends on whether defense attorneys actually use the new discovery opportunities to represent their clients more effectively. Evidence from digital platforms, which courts use to enable the exchange of evidence between prosecution and defense, reveals that defense attorneys sometimes fail to carry out their professional duty to review discovery.Analyzing a novel data set we obtained from digital evidence plat-forms used in Texas, we found that defense attorneys never accessed any available electronic discovery in a substantial number felony cases between 2018-2020. We also found that the access rate varied by county, year, offense type, attorney category, attorney experience, and file type.To better understand when and why attorneys neglect the available discovery, we supplemented the analysis of digital platform data with interviews of more than three dozen Texas criminal defense attorneys. We learned that defense attorneys were aware that many of their peers fail to review discovery in felony criminal cases. Our interviewees identified several explanations for the failure to access evidence. These include a lack of technological skills and support, the overwhelming volume of digital discovery, the client's desire for fast resolution of the case, the lesser gravity of some cases, high caseloads, low compensation, and in some cases, simple lack of diligence. We consider the implications of these attorney practices for ineffective assistance of counsel litigation, effective supervision of defense attorneys, and criminal law reform.

Hemingway's Neglected Short Fiction

Hemingway's Neglected Short Fiction PDF Author: Susan F. Beegel
Publisher: University of Alabama Press
ISBN: 0817305866
Category : Literary Criticism
Languages : en
Pages : 392

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Book Description
Some 25 Hemingway scholars critique Hemingway's works from the early apprentice fiction of 1919, stories Hemingway wrote, dog."

Chironian

Chironian PDF Author:
Publisher:
ISBN:
Category : Homeopathy
Languages : en
Pages : 526

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Book Description


Model Rules of Professional Conduct

Model Rules of Professional Conduct PDF Author: American Bar Association. House of Delegates
Publisher: American Bar Association
ISBN: 9781590318737
Category : Law
Languages : en
Pages : 216

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Book Description
The Model Rules of Professional Conduct provides an up-to-date resource for information on legal ethics. Federal, state and local courts in all jurisdictions look to the Rules for guidance in solving lawyer malpractice cases, disciplinary actions, disqualification issues, sanctions questions and much more. In this volume, black-letter Rules of Professional Conduct are followed by numbered Comments that explain each Rule's purpose and provide suggestions for its practical application. The Rules will help you identify proper conduct in a variety of given situations, review those instances where discretionary action is possible, and define the nature of the relationship between you and your clients, colleagues and the courts.

Natural Science

Natural Science PDF Author:
Publisher:
ISBN:
Category : Natural history
Languages : en
Pages : 442

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Book Description


Notices of the Proceedings

Notices of the Proceedings PDF Author: Royal Institution of Great Britain
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 232

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Book Description


Running on Empty

Running on Empty PDF Author: Jonice Webb
Publisher: Morgan James Publishing
ISBN: 161448242X
Category : Self-Help
Languages : en
Pages : 250

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Book Description
A large segment of the population struggles with feelings of being detached from themselves and their loved ones. They feel flawed, and blame themselves. Running on Empty will help them realize that they're suffering not because of something that happened to them in childhood, but because of something that didn't happen. It's the white space in their family picture, the background rather than the foreground. This will be the first self-help book to bring this invisible force to light, educate people about it, and teach them how to overcome it.