Multimodal Retinal Imaging Via OCT Multi-volume Averaging and Two Photon Excited Fluorescence PDF Download
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Author: William Newberry
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Advancements in optical imaging are needed to study vision robbing diseases. New technology can be developed using animal models, which can progress the understanding of both retinal function, and that of novel imaging methods. Fluorescence is a convenient source of contrast in the retina due to the relative ease of introducing extrinsic fluorophores, as well as its various opportunities for autofluorescence. two-photon excited fluorescence (TPEF) is a suitable modality of this, but its need for high incident powers arises concerns of damaging the retina. A pulsed laser coupled with high numerical aperture and adaptive optics aids to lower the required power, but sample motion remains an issue. In this thesis, I present on improvements made to a TPEF imaging system, as well as an algorithm that utilizes co-acquired optical coherence tomography (OCT) to aid in motion correction.
Author: William Newberry
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Advancements in optical imaging are needed to study vision robbing diseases. New technology can be developed using animal models, which can progress the understanding of both retinal function, and that of novel imaging methods. Fluorescence is a convenient source of contrast in the retina due to the relative ease of introducing extrinsic fluorophores, as well as its various opportunities for autofluorescence. two-photon excited fluorescence (TPEF) is a suitable modality of this, but its need for high incident powers arises concerns of damaging the retina. A pulsed laser coupled with high numerical aperture and adaptive optics aids to lower the required power, but sample motion remains an issue. In this thesis, I present on improvements made to a TPEF imaging system, as well as an algorithm that utilizes co-acquired optical coherence tomography (OCT) to aid in motion correction.
Author: Amresh Chopdar
Publisher: JP Medical Ltd
ISBN: 1907816607
Category : Medical
Languages : en
Pages : 188
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Book Description
span style="font-size: xx-small;"Retinal imaging techniques are used to diagnose and screen for various conditions such as macular degeneration and glaucoma. Equally importantly, they are used to monitor the progression of previously diagnosed conditions.
Author: H. Nida Sen
Publisher: Springer
ISBN: 3319236903
Category : Medical
Languages : en
Pages : 174
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Book Description
This book is a comprehensive guide to the imaging techniques that have revolutionized the diagnosis and management of uveitis during the past decade, including optical coherence tomography (OCT), enhanced depth imaging, fundus autofluorescence, and wide-field angiography. In addition, the current role of the traditional (invasive) gold standard techniques, fluorescein angiography and indocyanine green angiography, is described. Among the newer imaging modalities, detailed attention is paid to the various OCT technologies such as spectral domain OCT, enhanced-depth imaging OCT, and enface swept-source OCT. Further individual chapters focus on imaging using adaptive optics, multiview OCT, and OCT angiography. Uveitis can affect virtually any structure in the eye, and imaging of these structures is critical in the diagnosis, prognosis, and management of the disease. Increasing use and better understanding of the different modalities described in this book are sure to improve our knowledge of disease mechanisms and likely outcomes.
Author: J. Cunha-Vaz
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318063568
Category : Medical
Languages : en
Pages : 136
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Book Description
The introduction of new imaging methods has revolutionized the management of retinal diseases. Techniques like OCT angiography and fundus autofluorescence imaging have enabled the exploration of new perspectives for understanding the progress of diseases such as age-related macular degeneration (AMD) and diabetic retinopathy. Multimodal imaging of the retina will open new avenues for an integrated diagnostic approach in the future. This publication - like all volumes of the ‘ESASO Course Series’ - summarizes the essentials of the ESASO education courses. It provides an update for retina specialists and imaging technicians. Residents and trainees will also find it to be useful for learning about new imaging techniques.
Author: Josef F. Bille
Publisher: Springer
ISBN: 3030166384
Category : Medical
Languages : en
Pages : 407
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Book Description
This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.
Author: Martin Zinkernagel
Publisher: Springer
ISBN: 3030228789
Category : Medical
Languages : en
Pages : 121
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Book Description
This book focuses on the emerging non-invasive imaging technique of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). FLIO reveals unique information on retinal diseases, ranging from age-related macular degeneration and vascular diseases to hereditary retinal dystrophies. Fluorescence lifetimes enable the evaluation of disease progression before irreversible structural changes occur. The image acquisition is suitable for diagnostic purposes and follow-up examinations to investigate the natural course of disease, and to monitor the effects of possible therapies. This book fills the gap between available literature and gives state-of-the-art guidance on the principles of the FLIO technique, image acquisition, and data analysis. Written by a team of expert leaders within this field, this book will be relevant for scientists and clinicians with an interest in ophthalmoscopy.
Author: Margarida Barroso
Publisher: CRC Press
ISBN: 1351704494
Category : Science
Languages : en
Pages : 444
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Book Description
This book offers an overview of imaging techniques used to investigate cells and tissue in their native environment. It covers the range of imaging approaches used, as well as the application of those techniques to the study of biological processes in cells and whole tissues within living organisms.
Author: Francesco S. Pavone
Publisher: Taylor & Francis
ISBN: 1439849153
Category : Science
Languages : en
Pages : 465
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Book Description
Second-harmonic generation (SHG) microscopy has shown great promise for imaging live cells and tissues, with applications in basic science, medical research, and tissue engineering. Second Harmonic Generation Imaging offers a complete guide to this optical modality, from basic principles, instrumentation, methods, and image analysis to biomedical a
Author: National Research Council
Publisher: National Academies Press
ISBN: 030916463X
Category : Science
Languages : en
Pages : 222
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Book Description
Scientists and engineers have long relied on the power of imaging techniques to help see objects invisible to the naked eye, and thus, to advance scientific knowledge. These experts are constantly pushing the limits of technology in pursuit of chemical imagingâ€"the ability to visualize molecular structures and chemical composition in time and space as actual events unfoldâ€"from the smallest dimension of a biological system to the widest expanse of a distant galaxy. Chemical imaging has a variety of applications for almost every facet of our daily lives, ranging from medical diagnosis and treatment to the study and design of material properties in new products. In addition to highlighting advances in chemical imaging that could have the greatest impact on critical problems in science and technology, Visualizing Chemistry reviews the current state of chemical imaging technology, identifies promising future developments and their applications, and suggests a research and educational agenda to enable breakthrough improvements.
Author: Luc Téot
Publisher: Springer Nature
ISBN: 3030447669
Category : Medical
Languages : en
Pages : 553
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Book Description
This text book is open access under a CC BY 4.0 license. Written by a group of international experts in the field and the result of over ten years of collaboration, it allows students and readers to gain to gain a detailed understanding of scar and wound treatment – a topic still dispersed among various disciplines. The content is divided into three parts for easy reference. The first part focuses on the fundamentals of scar management, including assessment and evaluation procedures, classification, tools for accurate measurement of all scar-related elements (volume density, color, vascularization), descriptions of the different evaluation scales. It also features chapters on the best practices in electronic-file storage for clinical reevaluation and telemedicine procedures for safe remote evaluation. The second section offers a comprehensive review of treatment and evidence-based technologies, presenting a consensus of the various available guidelines (silicone, surgery, chemical injections, mechanical tools for scar stabilization, lasers). The third part evaluates the full range of emerging technologies offered to physicians as alternative or complementary solutions for wound healing (mechanical, chemical, anti-proliferation). Textbook on Scar Management will appeal to trainees, fellows, residents and physicians dealing with scar management in plastic surgery, dermatology, surgery and oncology, as well as to nurses and general practitioners
