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Author: Long-Biao Cui
Publisher: Frontiers Media SA
ISBN: 2832514502
Category : Science
Languages : en
Pages : 157
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Book Description
Author: Long-Biao Cui
Publisher: Frontiers Media SA
ISBN: 2832514502
Category : Science
Languages : en
Pages : 157
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Book Description
Author: Andreas Pohlmann
Publisher: Humana
ISBN: 9781071609774
Category : Science
Languages : en
Pages : 725
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Book Description
This Open Access volume provides readers with an open access protocol collection and wide-ranging recommendations for preclinical renal MRI used in translational research. The chapters in this book are interdisciplinary in nature and bridge the gaps between physics, physiology, and medicine. They are designed to enhance training in renal MRI sciences and improve the reproducibility of renal imaging research. Chapters provide guidance for exploring, using and developing small animal renal MRI in your laboratory as a unique tool for advanced in vivo phenotyping, diagnostic imaging, and research into potential new therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Preclinical MRI of the Kidney: Methods and Protocols is a valuable resource and will be of importance to anyone interested in the preclinical aspect of renal and cardiorenal diseases in the fields of physiology, nephrology, radiology, and cardiology. This publication is based upon work from COST Action PARENCHIMA, supported by European Cooperation in Science and Technology (COST). COST (www.cost.eu) is a funding agency for research and innovation networks. COST Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation. PARENCHIMA (renalmri.org) is a community-driven Action in the COST program of the European Union, which unites more than 200 experts in renal MRI from 30 countries with the aim to improve the reproducibility and standardization of renal MRI biomarkers.
Author: Max Wintermark
Publisher: Elsevier Health Sciences
ISBN: 0443183953
Category : Medical
Languages : en
Pages : 233
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Book Description
In this issue of MRI Clinics, guest editors Drs. Max Wintermark and Ananth Madhuranthakam bring their considerable expertise to the topic of MR Perfusion. Top experts in the field discuss all three MR perfusion techniques (DSC, DCE, and ASL), as well as provide separate articles on evaluation of gliomas, breast cancer, musculoskeletal, prostate, and heart. Contains 13 relevant, practice-oriented topics including perfusion imaging for brain tumors; dynamic susceptibility contrast (DSC) MR perfusion; arterial spin labelling (ASL) MR perfusion; MR perfusion imaging of prostate; dynamic contrast-enhanced (DCE) MR perfusion; MR perfusion imaging for breast cancer; and more. Provides in-depth clinical reviews on MR perfusion, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Author: Peter B. Barker
Publisher: Cambridge University Press
ISBN: 1107013399
Category : Medical
Languages : en
Pages : 373
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Book Description
This concise and comprehensive review uniquely contains all the information required to perform and interpret clinical MR perfusion imaging.
Author: Michael Chappell
Publisher: Oxford University Press
ISBN: 0198793812
Category : Medical
Languages : en
Pages : 157
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Book Description
Arterial spin labeling (ASL) magnetic resonance imaging (MRI) is unique in being a completely non-invasive method for imaging perfusion in the brain. Relying upon a blood-borne tracer that is created by the MRI scanner itself, ASL is becoming a popular tool to study cerebral perfusion, as well as how this perfusion changes in response to neuronal activity or in disease. This primer provides an introduction to perfusion quantification using ASL MRI, focusing both on the methods needed to extract perfusion-weighted images and on how to quantify perfusion and other hemodynamic parameters. Starting with the simplest implementation of ASL, the primer details all the common acquisition methods, as well as the subsequent analysis steps required to quantify perfusion in an individual, detect changes in perfusion in response to neural activity or pharmacological intervention, and examine perfusion variations across groups of individuals. This is supported with examples from real data illustrating all the major steps in the analysis process, linked to online material where the reader can undertake the same analysis for themselves.
Author:
Publisher:
ISBN: 9789461825421
Category :
Languages : en
Pages : 235
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Book Description
Author: Richard B. Buxton
Publisher: Cambridge University Press
ISBN: 0521899958
Category : Medical
Languages : en
Pages : 479
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Book Description
This is the second edition of a useful introductory book on a technique that has revolutionized neuroscience, specifically cognitive neuroscience. Functional magnetic resonance imaging (fMRI) has now become the standard tool for studying the brain systems involved in cognitive and emotional processing. It has also been a major factor in the consilience of the fields of neurobiology, cognitive psychology, social psychology, radiology, physics, mathematics, engineering, and even philosophy. Written and edited by a clinician-scientist in the field, this book remains an excellent user's guide to t
Author: James Duffin
Publisher: Frontiers Media SA
ISBN: 2832550215
Category : Science
Languages : en
Pages : 170
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Book Description
The acquisition of resting cerebral perfusion measures using magnetic resonance imaging (MRI) is one of the assessments of cerebrovascular health used to discern how well patients are coping with anatomical changes such as stenosis, and other factors impacting the supply of blood flow to the brain. Perfusion measures may be obtained using several MRI based techniques including arterial spin labeling (ASL) and dynamic contrast enhanced methods that rely on injected contrast agents such as gadolinium. Recently hypoxia-induced changes in deoxyhemoglobin have been used as a non-invasive contrast agent, measuring the resulting changes in blood oxygen dependent (BOLD) signals with MRI. With each approach, the means through which voxel-wise cerebral perfusion information is derived differs, leading to the development a variety of analysis methods in recent studies. This Research Topic is intended to attract manuscripts that advance the use of resting cerebral perfusion measures in clinical assessments of cerebrovascular health. In pursuit of this aim a better understanding of several aspects are needed.
Author: Julian Schroeder
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Several studies have suggested a correlation between impairment of cognitive function and asymptomatic carotid artery stenosis without ischemic cerebral brain lesions. Hypoperfusion has been discussed as a possible underlying pathophysiological cause. It remains unclear whether hypoperfusion alone without evidence of infarction is sufficient to cause cognitive decline. In this study, we evaluated cognitive performance and cerebral perfusion changes in patients with asymptomatic carotid artery stenosis by arterial spin labeling (ASL) perfusion MRI before and after revascularization therapy.Methods:17 asymptomatic patients with unilateral high-grade (u226570%) carotid artery stenosis without evidence of structural brain lesions underwent ASL perfusion MRI and cognitive testing (MMSE, DemTect, Clock-Drawing Test, Trail-Making Test, Stroop Test) before and 6-8 weeks after revascularization therapy by endarterectomy or stenting. Multiparametric perfusion maps (cerebral blood flow (ASL-CBF), bolus arrival time (ASL-BAT)) were calculated and analyzed by vascular territory. Relative perfusion values were calculated. Results:A significant impact of revascularization therapy was shown through multivariate analysis on all perfusion measures analyzed. MCA borderzones were identified as territories showing significant hypoperfuion at baseline post-hoc testing in both ASL-CBF and ASL-BAT. All perfusion alterations normalized after revascularization. No significant correlation of cognitive test results with perfusion parameters was observed. Cognitive Performance showed no significant change after revascularization. Conclusion:Our study was able to show perfusion alterations in asymptomatic patients with high grade carotid artery stenosis in the absence of structural brain lesions, which proved fully reversible after revascularization therapy. In this cohort of asymptomatic patients we did not observe an association of hypoperfusion with cognitive performance.
Author: Denis Le Bihan
Publisher: CRC Press
ISBN: 0429763492
Category : Medical
Languages : en
Pages : 563
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Book Description
First book ever on the topic Discusses current concepts and methodological issues for the successful implementation of IVIM MRI to investigate tissue perfusion non-invasively Covers a wide range of clinical applications Contributions by leading experts in the field from USA, Europe, and Asia and written with a good balance of methodological and clinical chapters Includes an extensive bibliography for further reading
