Molybdenum-100 Targets for Cyclotron Production of Technetium-99m

Molybdenum-100 Targets for Cyclotron Production of Technetium-99m PDF Author: Gabriel Joseph Surette
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ISBN:
Category :
Languages : en
Pages :

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Molybdenum-100 Targets for Cyclotron Production of Technetium-99m

Molybdenum-100 Targets for Cyclotron Production of Technetium-99m PDF Author: Gabriel Joseph Surette
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Molybdenum-99 for Medical Imaging

Molybdenum-99 for Medical Imaging PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309445310
Category : Medical
Languages : en
Pages : 264

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Book Description
The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.

Cyclotron Based Production of Technetium-99m

Cyclotron Based Production of Technetium-99m PDF Author: International Atomic Energy Agency
Publisher:
ISBN: 9789201029164
Category : Technology & Engineering
Languages : en
Pages : 0

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Book Description
This publication presents a comprehensive overview of the technologies involved in the production of cyclotron based 99mTc. These would include techniques relevant to preparation of targets, irradiation of targets under high beam currents, target processing, target recovery and quality control of the final product. The publication provides broad information, well supported with references, on improved production routes and improved separation and purification of cyclotron based 99mTc. These approaches achieve high specific activity and chemical purity of 99mTc suitable for labelling molecules of medical interest and also enable spare capacity to be available at medical cyclotron centres. The readership of this publication is scientists interested in translating this technology to practice, technologists already working with cyclotrons wanting to enhance the utility of the existing machines and managers who are in the process of setting up facilities in their countries. Students working towards higher level degrees in related fields may also benefit from this publication.

Medical Isotope Production Without Highly Enriched Uranium

Medical Isotope Production Without Highly Enriched Uranium PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309130395
Category : Medical
Languages : en
Pages : 220

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Book Description
This book is the product of a congressionally mandated study to examine the feasibility of eliminating the use of highly enriched uranium (HEU2) in reactor fuel, reactor targets, and medical isotope production facilities. The book focuses primarily on the use of HEU for the production of the medical isotope molybdenum-99 (Mo-99), whose decay product, technetium-99m3 (Tc-99m), is used in the majority of medical diagnostic imaging procedures in the United States, and secondarily on the use of HEU for research and test reactor fuel. The supply of Mo-99 in the U.S. is likely to be unreliable until newer production sources come online. The reliability of the current supply system is an important medical isotope concern; this book concludes that achieving a cost difference of less than 10 percent in facilities that will need to convert from HEU- to LEU-based Mo-99 production is much less important than is reliability of supply.

Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets

Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 030946627X
Category : Medical
Languages : en
Pages : 87

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Book Description
Participants of the July 17-18, 2017, symposium titled Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets examined current trends in molybdenum-99 production, prospects for new global supplies, and technical, economic, regulatory, and other considerations for supplying molybdenum-99 to global markets. This publication summarizes the presentations and discussions from the symposium.

Direct Production of Technetium-99m and Molybdenum-99 with Accelerated Protons

Direct Production of Technetium-99m and Molybdenum-99 with Accelerated Protons PDF Author: Iad Mirshad
Publisher:
ISBN:
Category :
Languages : en
Pages : 236

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Instruments and Methods for Cyclotron Produced Radioisotopes

Instruments and Methods for Cyclotron Produced Radioisotopes PDF Author: Saverio Braccini
Publisher: MDPI
ISBN: 3039282026
Category : Technology & Engineering
Languages : en
Pages : 230

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Book Description
The focus of this Special Issue is aimed at enhancing the discussion of Engineering Education, particularly related to technological and professional learning. In the 21st century, students face a challenging demand: they are expected to have the best scientific expertise, but also highly developed social skills and qualities like teamwork, creativity, communication, or leadership. Even though students and teachers are becoming more aware of this necessity, there is still a gap between academic life and the professional world. In this Special Edition Book, the reader can find works tackling interesting topics such as educational resources addressing students’ development of competencies, the importance of final year projects linked to professional environments, and multicultural or interdisciplinary challenges.

Cyclotron Produced Radionuclides

Cyclotron Produced Radionuclides PDF Author:
Publisher:
ISBN: 9789201002082
Category : Business & Economics
Languages : en
Pages : 0

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Book Description
This book provides a comprehensive treatment of cyclotrons, with a special emphasis on production of radionuclides. Individual sections are devoted to accelerator technology, theoretical aspects of nuclear reactions, the technology behind targetry, techniques for preparation of targets, irradiation of targets under high beam currents, target processing and target recovery. This book will appeal to scientists and technologists interested in translating cyclotron technology into practice, as well as postgraduate students in this field.

Fundamentals of Nuclear Pharmacy

Fundamentals of Nuclear Pharmacy PDF Author: Gopal B. Saha
Publisher: Springer
ISBN: 3319575805
Category : Medical
Languages : en
Pages : 430

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Book Description
Currently an estimated 17 million nuclear medicine procedures are performed each year in the US and constantly evolving, as new radiopharmaceuticals and imaging techniques are introduced for better diagnosis and treatment of human diseases. In keeping up with new developments, the Seventh Edition of Fundamentals of Nuclear Pharmacy chronicles the advancements in radiopharmaceuticals and their use in clinical applications. It discusses basic concepts such as the atom, radioactive decay, instrumentation and production of radionuclides, and explores the design, labeling, characteristics and quality control of radiopharmaceuticals. Radiation regulations and diagnostic and therapeutic applications of radiopharmaceuticals are detailed. Thoroughly updated, the Seventh Edition includes new topics such as alternative productions of 99Mo; production of 64Cu, 86Y, 89Zr, 177Lu, 223Ra; synthesis and clinical uses of new radiopharmaceuticals such as DaTscan, Xofigo, Amyvid, Neuraceq, Vizamyl, Axumin and 68Ga-DOTATATE; dosimetry of new radiopharmaceuticals; theranostic agents and translational medicine. It features numerous examples, diagrams, and images to further clarify the information and offers end- of-chapter questions to help readers assess their comprehension of the material. Recognized as a classic text on nuclear chemistry and pharmacy and acclaimed for its concise and easy-to-understand presentation, Fundamentals of Nuclear Pharmacy is an authoritative resource for nuclear medicine physicians, residents, students, and technologists.

Molybdenum Targets for Production of 99mTc by a Medical Cyclotron

Molybdenum Targets for Production of 99mTc by a Medical Cyclotron PDF Author: L. Matei
Publisher:
ISBN:
Category :
Languages : en
Pages :

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