Molecularizing Biology and Medicine

Molecularizing Biology and Medicine PDF Author: Soraya de Chadarevian
Publisher: Taylor & Francis
ISBN: 1135298009
Category : History
Languages : en
Pages : 586

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Book Description
The contributors present a coherent set of case studies of practices, technologies and strategies aimed at the isolation, investigation, manipulation, production, and uses of molecules including vitamins, hormones, blood products, antibiotics, and vaccines. These case studies examine how processes of molecularization were set in motion in the inter-war period, how they were used as a resource in the biomedical 'mobilization' of World War II, and how new alliances and strategies created as part of the war effort played a central role in the reorganisation of biomedicine in the post-war period.

Molecularizing Biology and Medicine

Molecularizing Biology and Medicine PDF Author: Soraya de Chadarevian
Publisher: Taylor & Francis
ISBN: 1135298009
Category : History
Languages : en
Pages : 586

Get Book Here

Book Description
The contributors present a coherent set of case studies of practices, technologies and strategies aimed at the isolation, investigation, manipulation, production, and uses of molecules including vitamins, hormones, blood products, antibiotics, and vaccines. These case studies examine how processes of molecularization were set in motion in the inter-war period, how they were used as a resource in the biomedical 'mobilization' of World War II, and how new alliances and strategies created as part of the war effort played a central role in the reorganisation of biomedicine in the post-war period.

 PDF Author:
Publisher: IOS Press
ISBN:
Category :
Languages : en
Pages : 4947

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Book Description


Biology, Computing, and the History of Molecular Sequencing

Biology, Computing, and the History of Molecular Sequencing PDF Author: M. García-Sancho
Publisher: Springer
ISBN: 0230370934
Category : Science
Languages : en
Pages : 253

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Book Description
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.

The Recombinant University

The Recombinant University PDF Author: Doogab Yi
Publisher: University of Chicago Press
ISBN: 022621611X
Category : Science
Languages : en
Pages : 331

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Book Description
The advent of recombinant DNA technology in the 1970s was a key moment in the history of both biotechnology and the commercialization of academic research. Doogab Yi’s The Recombinant University draws us deeply into the academic community in the San Francisco Bay Area, where the technology was developed and adopted as the first major commercial technology for genetic engineering. In doing so, it reveals how research patronage, market forces, and legal developments from the late 1960s through the early 1980s influenced the evolution of the technology and reshaped the moral and scientific life of biomedical researchers. Bay Area scientists, university administrators, and government officials were fascinated by and increasingly engaged in the economic and political opportunities associated with the privatization of academic research. Yi uncovers how the attempts made by Stanford scientists and administrators to demonstrate the relevance of academic research were increasingly mediated by capitalistic conceptions of knowledge, medical innovation, and the public interest. Their interventions resulted in legal shifts and moral realignments that encouraged the privatization of academic research for public benefit. The Recombinant University brings to life the hybrid origin story of biotechnology and the ways the academic culture of science has changed in tandem with the early commercialization of recombinant DNA technology.

Bio-Objects

Bio-Objects PDF Author: Niki Vermeulen
Publisher: Routledge
ISBN: 1317174224
Category : Medical
Languages : en
Pages : 241

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Book Description
Increasing knowledge of the biological is fundamentally transforming what life itself means and where its boundaries lie. New developments in the biosciences - especially through the molecularisation of life - are (re)shaping healthcare and other aspects of our society. This cutting edge volume studies contemporary bio-objects, or the categories, materialities and processes that are central to the configuring of 'life' today, as they emerge, stabilize and circulate through society. Examining a variety of bio-objects in contexts beyond the laboratory, Bio-Objects: Life in the 21st Century explores new ways of thinking about how novel bio-objects enter contemporary life, analysing the manner in which, among others, the boundaries between human and animal, organic and non-organic, and being 'alive' and the suspension of living, are questioned, destabilised and in some cases re-established. Thematically organised around questions of changing boundaries; the governance and regulation of bio-objects; and changing social, economic and political relations, this book presents rich new case studies from Europe that will be of interest to scholars of science and technology studies, social theory, sociology and law.

Pursuing the Unity of Science

Pursuing the Unity of Science PDF Author: Harmke Kamminga
Publisher: Routledge
ISBN: 1317073061
Category : History
Languages : en
Pages : 258

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Book Description
From 1918 to the late 1940s, a host of influential scientists and intellectuals in Europe and North America were engaged in a number of far-reaching unity of science projects. In this period of deep social and political divisions, scientists collaborated to unify sciences across disciplinary boundaries and to set up the international scientific community as a model for global political co-operation. They strove to align scientific and social objectives through rational planning and to promote unified science as the driving force of human civilization and progress. This volume explores the unity of science movement, providing a synthetic view of its pursuits and placing it in its historical context as a scientific and political force. Through a coherent set of original case studies looking at the significance of various projects and strategies of unification, the book highlights the great variety of manifestations of this endeavour. These range from unifying nuclear physics to the evolutionary synthesis, and from the democratization of scientific planning to the utopianism of H.G. Wells's world state. At the same time, the collection brings out the substantive links between these different pursuits, especially in the form of interconnected networks of unification and the alignment of objectives among them. Notably, it shows that opposition to fascism, using the instrument of unified science, became the most urgent common goal in the 1930s and 1940s. In addressing these issues, the book makes visible important historical developments, showing how scientists participated in, and actively helped to create, an interwar ideology of unification, and bringing to light the cultural and political significance of this enterprise.

Life Histories of Genetic Disease

Life Histories of Genetic Disease PDF Author: Andrew J. Hogan
Publisher: Johns Hopkins University Press+ORM
ISBN: 1421420759
Category : Medical
Languages : en
Pages : 264

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Book Description
A richly detailed history that “uncovers the challenges and limitations of our increasing reliance on genetic data in medical decision making” (Shobita Parthasarathy, author of Building Genetic Medicine). Medical geneticists began mapping the chromosomal infrastructure piece by piece in the 1970s by focusing on what was known about individual genetic disorders. Five decades later, their infrastructure had become an edifice for prevention, allowing expectant parents to test prenatally for hundreds of disease-specific mutations using powerful genetic testing platforms. In this book, Andrew J. Hogan explores how various diseases were “made genetic” after 1960, with the long-term aim of treating and curing them using gene therapy. In the process, he explains, these disorders were located in the human genome and became targets for prenatal prevention, while the ongoing promise of gene therapy remained on the distant horizon. In narrating the history of research that contributed to diagnostic genetic medicine, Hogan describes the expanding scope of prenatal diagnosis and prevention. He draws on case studies of Prader-Willi, fragile X, DiGeorge, and velo-cardio-facial syndromes to illustrate that almost all testing in medical genetics is inseparable from the larger—and increasingly “big data”–oriented—aims of biomedical research. Hogan also reveals how contemporary genetic testing infrastructure reflects an intense collaboration among cytogeneticists, molecular biologists, and doctors specializing in human malformation. Hogan critiques the modern ideology of genetic prevention, which suggests all pregnancies are at risk for genetic disease and should be subject to extensive genomic screening. He examines the dilemmas and ethics of the use of prenatal diagnostic information in an era when medical geneticists and biotechnology companies offer whole genome prenatal screening—essentially searching for any disease-causing mutation. Hogan’s analysis is animated by ongoing scientific and scholarly debates about the extent to which the preventive focus in contemporary medical genetics resembles the aims of earlier eugenicists. Written for historians, sociologists, and anthropologists of science and medicine, as well as bioethics scholars, physicians, geneticists, and families affected by genetic conditions, Life Histories of Genetic Disease is a profound exploration of the scientific culture surrounding malformation and mutation.

Modern Flu

Modern Flu PDF Author: Michael Bresalier
Publisher: Springer Nature
ISBN: 1137339543
Category : History
Languages : en
Pages : 476

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Book Description
Ninety years after the discovery of human influenza virus, Modern Flu traces the history of this breakthrough and its implications for understanding and controlling influenza ever since. Examining how influenza came to be defined as a viral disease in the first half of the twentieth century, it argues that influenza’s viral identity did not suddenly appear with the discovery of the first human influenza virus in 1933. Instead, it was rooted in the development of medical virus research and virological ways of knowing that grew out of a half-century of changes and innovations in medical science that were shaped through two influenza pandemics, two world wars, and by state-sponsored programs to scientifically modernise British medicine. A series of transformations, in which virological ideas and practices were aligned with and incorporated into medicine and public health, underpinned the viralisation of influenza in the 1930s and 1940s. Collaboration, conflict and exchange between researchers, medical professionals and governmental bodies lay at the heart of this process. This book is a history of how virus researchers, clinicians, and epidemiologists, medical scientific and public health bodies, and institutions, and philanthropies in Britain, the USA and beyond, forged a new medical consensus on the identity and nature of influenza. Shedding new light on the modern history of influenza, this book is a timely account of how ways of knowing and controlling this intractable epidemic disease became viral.

Science and Ideology

Science and Ideology PDF Author: Mark Walker
Publisher: Routledge
ISBN: 1136466622
Category : History
Languages : en
Pages : 284

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Book Description
Does science work best in a democracy? Were 'Soviet' or 'Nazi' science fundamentally different from science in the USA? These questions have been passionately debated in the recent past. Particular developments in science took place under particular political regimes, but they may or may not have been directly determined by them. Science and Ideology brings together a number of comparative case studies to examine the relationship between science and the dominant ideology of a state. Cybernetics in the USA is compared to France and the Soviet Union. Postwar Allied science policy in occupied Germany is juxtaposed to that in Japan. The essays are narrowly focussed, yet cover a wide range of countries and ideologies. The collection provides a unique comparative history of scientific policies and practices in the 20th century.

Interferon

Interferon PDF Author: Toine Pieters
Publisher: Routledge
ISBN: 1134293062
Category : Interferon
Languages : en
Pages : 285

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Book Description
This book charts the history and development of one of the most important medical substances of the twentieth century, Interferon, as a drug.