From Molecules to Networks

From Molecules to Networks PDF Author: Ruth Heidelberger
Publisher: Academic Press
ISBN: 0080920837
Category : Psychology
Languages : en
Pages : 654

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Book Description
An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. From Molecules to Networks provides the solid foundation of the morphologic, biochemical, and biophysical properties of nerve cells. All chapters have been thoroughly revised for this second edition to reflect the significant advances of the past 5 years. The new edition expands on the network aspects of cellular neurobiology by adding a new chapter, Information Processing in Neural Networks, and on the relation of cell biological processes to various neurological diseases. The new concluding chapter illustrates how the great strides in understanding the biochemical and biophysical properties of nerve cells have led to fundamental insights into important aspects of neurodegenerative disease. - Written and edited by leading experts in the field, the second edition completely and comprehensively updates all chapters of this unique textbook - Discusses emerging new understanding of non-classical molecules that affect neuronal signaling - Full colour, professional graphics throughout - Includes two new chapters: Information Processing in Neural Networks - describes the principles of operation of neural networks and the key circuit motifs that are common to many networks in the nervous system. Molecular and Cellular Mechanisms of Neurodegenerative Disease - introduces the progress made in the last 20 years in elucidating the cellular and molecular mechanisms underlying brain disorders, including Amyotrophic Lateral Sclerosis (ALS), Parkinson disease, and Alzheimer's disease

From Molecules to Networks

From Molecules to Networks PDF Author: Ruth Heidelberger
Publisher: Academic Press
ISBN: 0080920837
Category : Psychology
Languages : en
Pages : 654

Get Book Here

Book Description
An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. From Molecules to Networks provides the solid foundation of the morphologic, biochemical, and biophysical properties of nerve cells. All chapters have been thoroughly revised for this second edition to reflect the significant advances of the past 5 years. The new edition expands on the network aspects of cellular neurobiology by adding a new chapter, Information Processing in Neural Networks, and on the relation of cell biological processes to various neurological diseases. The new concluding chapter illustrates how the great strides in understanding the biochemical and biophysical properties of nerve cells have led to fundamental insights into important aspects of neurodegenerative disease. - Written and edited by leading experts in the field, the second edition completely and comprehensively updates all chapters of this unique textbook - Discusses emerging new understanding of non-classical molecules that affect neuronal signaling - Full colour, professional graphics throughout - Includes two new chapters: Information Processing in Neural Networks - describes the principles of operation of neural networks and the key circuit motifs that are common to many networks in the nervous system. Molecular and Cellular Mechanisms of Neurodegenerative Disease - introduces the progress made in the last 20 years in elucidating the cellular and molecular mechanisms underlying brain disorders, including Amyotrophic Lateral Sclerosis (ALS), Parkinson disease, and Alzheimer's disease

Bacterial Molecular Networks

Bacterial Molecular Networks PDF Author: Denis Thieffry
Publisher: Humana Press
ISBN: 9781493961566
Category : Science
Languages : en
Pages : 560

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Book Description
Bacterial Molecular Networks provides authoritative descriptions of various experimental and computational methods that enable the characterization and analysis of molecular interaction networks.

Molecular Networks

Molecular Networks PDF Author: Mir Wais Hosseini
Publisher: Springer Science & Business Media
ISBN: 3642013678
Category : Science
Languages : en
Pages : 173

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Book Description


Functional Coherence of Molecular Networks in Bioinformatics

Functional Coherence of Molecular Networks in Bioinformatics PDF Author: Mehmet Koyutürk
Publisher: Springer Science & Business Media
ISBN: 1461403200
Category : Science
Languages : en
Pages : 235

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Book Description
Molecular networks provide descriptions of the organization of various biological processes, including cellular signaling, metabolism, and genetic regulation. Knowledge on molecular networks is commonly used for systems level analysis of biological function; research and method development in this area has grown tremendously in the past few years. This book will provide a detailed review of existing knowledge on the functional characterization of biological networks. In 15 chapters authored by an international group of prolific systems biology and bioinformatics researchers, it will organize, conceptualize, and summarize the existing core of research results and computational methods on understanding biological function from a network perspective.

Phase Transitions and Self-Organization in Electronic and Molecular Networks

Phase Transitions and Self-Organization in Electronic and Molecular Networks PDF Author: J.C. Phillips
Publisher: Springer Science & Business Media
ISBN: 030646568X
Category : Science
Languages : en
Pages : 455

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Book Description
Advances in nanoscale science show that the properties of many materials are dominated by internal structures. This volume discusses this topic, beginning with an examination of the phase diagrams and phase transitions of materials known to be composed of molecular networks.

Modeling and Analysis of Bio-molecular Networks

Modeling and Analysis of Bio-molecular Networks PDF Author: Jinhu Lü
Publisher: Springer Nature
ISBN: 981159144X
Category : Science
Languages : en
Pages : 464

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Book Description
This book addresses a number of questions from the perspective of complex systems: How can we quantitatively understand the life phenomena? How can we model life systems as complex bio-molecular networks? Are there any methods to clarify the relationships among the structures, dynamics and functions of bio-molecular networks? How can we statistically analyse large-scale bio-molecular networks? Focusing on the modeling and analysis of bio-molecular networks, the book presents various sophisticated mathematical and statistical approaches. The life system can be described using various levels of bio-molecular networks, including gene regulatory networks, and protein-protein interaction networks. It first provides an overview of approaches to reconstruct various bio-molecular networks, and then discusses the modeling and dynamical analysis of simple genetic circuits, coupled genetic circuits, middle-sized and large-scale biological networks, clarifying the relationships between the structures, dynamics and functions of the networks covered. In the context of large-scale bio-molecular networks, it introduces a number of statistical methods for exploring important bioinformatics applications, including the identification of significant bio-molecules for network medicine and genetic engineering. Lastly, the book describes various state-of-art statistical methods for analysing omics data generated by high-throughput sequencing. This book is a valuable resource for readers interested in applying systems biology, dynamical systems or complex networks to explore the truth of nature.

Models and Algorithms for Biomolecules and Molecular Networks

Models and Algorithms for Biomolecules and Molecular Networks PDF Author: Bhaskar DasGupta
Publisher: John Wiley & Sons
ISBN: 1119162270
Category : Science
Languages : en
Pages : 260

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Book Description
By providing expositions to modeling principles, theories, computational solutions, and open problems, this reference presents a full scope on relevant biological phenomena, modeling frameworks, technical challenges, and algorithms. Up-to-date developments of structures of biomolecules, systems biology, advanced models, and algorithms Sampling techniques for estimating evolutionary rates and generating molecular structures Accurate computation of probability landscape of stochastic networks, solving discrete chemical master equations End-of-chapter exercises

Molecular Network Study of Pituitary Adenomas

Molecular Network Study of Pituitary Adenomas PDF Author: Xianquan Zhan
Publisher: Frontiers Media SA
ISBN: 288963602X
Category :
Languages : en
Pages : 210

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Book Description


Gene Regulatory Networks

Gene Regulatory Networks PDF Author: Guido Sanguinetti
Publisher: Humana
ISBN: 9781493988815
Category : Science
Languages : en
Pages : 0

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Book Description
This volume explores recent techniques for the computational inference of gene regulatory networks (GRNs). The chapters in this book cover topics such as methods to infer GRNs from time-varying data; the extraction of causal information from biological data; GRN inference from multiple heterogeneous data sets; non-parametric and hybrid statistical methods; the joint inference of differential networks; and mechanistic models of gene regulation dynamics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, descriptions of recently developed methods for GRN inference, applications of these methods on real and/ or simulated biological data, and step-by-step tutorials on the usage of associated software tools. Cutting-edge and thorough, Gene Regulatory Networks: Methods and Protocols is an essential tool for evaluating the current research needed to further address the common challenges faced by specialists in this field.

Mass Spectrometry for the Novice

Mass Spectrometry for the Novice PDF Author: John Greaves
Publisher: CRC Press
ISBN: 1420094203
Category : Medical
Languages : en
Pages : 309

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Book Description
With usage of mass spectrometry continually expanding, an increasing number of scientists, technicians, students, and physicians are coming into contact with this valuable technique. Mass spectrometry has many uses, both qualitative and quantitative, from analyzing simple gases to environmental contaminants, pharmaceuticals, and complex biopolymers