Molecular Mechanisms Underpinning the Development of Obesity PDF Download
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Author: Clévio Nóbrega
Publisher: Springer
ISBN: 3319127667
Category : Medical
Languages : en
Pages : 200
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Book Description
Obesity is a multi-factorial disease, in which an excess of accumulated body fat can reach levels capable of affecting health. It results from an interplay between environmental factors, eating behavior, genes, epigenetics, and neuronal stimuli. The main aim of this book is to provide a state-of-the-art revision about the molecular mechanisms underpinning the development of obesity, reviewing the current knowledge in areas like monogenic and polygenic obesity forms, but also providing an updated view of the emerging knowledge about epigenetics, nutrigenomics, and neuronal aspects that also contribute to obesity.
Author: Clévio Nóbrega
Publisher: Springer
ISBN: 3319127667
Category : Medical
Languages : en
Pages : 200
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Book Description
Obesity is a multi-factorial disease, in which an excess of accumulated body fat can reach levels capable of affecting health. It results from an interplay between environmental factors, eating behavior, genes, epigenetics, and neuronal stimuli. The main aim of this book is to provide a state-of-the-art revision about the molecular mechanisms underpinning the development of obesity, reviewing the current knowledge in areas like monogenic and polygenic obesity forms, but also providing an updated view of the emerging knowledge about epigenetics, nutrigenomics, and neuronal aspects that also contribute to obesity.
Author: Clevio Nobrega
Publisher:
ISBN: 9783319127675
Category :
Languages : en
Pages : 208
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Book Description
Author: Paramjit S. Tappia
Publisher: Springer Nature
ISBN: 3030847632
Category : Medical
Languages : en
Pages : 420
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Book Description
Global health has been challenged with the dawning of the era of the obesity epidemic, and thus as a consequence, strategies to reduce obesity have become public health priorities. According to the United Nations, obesity has been identified as a concern for achieving Sustainable Development Goals. Obesity is a serious health problem with an increased risk of several common diseases including diabetes, cardiovascular disease, and cancer. Although the fundamental cause of obesity and overweight is an imbalance between calorie intake and calorie expenditure, the underlying biochemical and metabolic processes that cause obesity are not fully understood. Two earlier volumes dedicated to the subject of obesity, published in the series “Advances in Biochemistry in Health and Disease” focused on the pathophysiology of obesity-induced health complications and the biochemistry of cardiovascular dysfunction in obesity. This book brings together contributions from international experts in the field to describe advancements on the mechanisms leading to development of obesity and related complications. There are 21 chapters in two different parts in this book, comprising of Part I: Pathophysiologic Mechanisms of Obesity (11 chapters) and Part II: Therapeutic Mechanisms of Obesity (10 chapters). This book will serve as a resource and be of interest to health professionals, medical students, fellows, residents and graduate students. It will also evoke innovative research and effective approaches for the prevention of obesity. This volume will accentuate that obesity is a major health hazard in its own right and that appropriate public health measures should be implemented to prevent or reduce or even reverse the impact of this global chronic disease.
Author: Juergen Eckel
Publisher: Springer Nature
ISBN: 3030999955
Category : Medical
Languages : en
Pages : 508
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Book Description
Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation. This edition of the "Handbook of Experimental Pharmacology" aims to analyze new insight into the pathophysiology of obesity, to decipher the complex links to diabetes and its complications, and to collect most recent information on new strategies for prevention and treatment of obesity and diabetes.
Author: Lotte Meinert
Publisher: Berghahn Books
ISBN: 1800733054
Category : Social Science
Languages : en
Pages : 274
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Book Description
Expanding our understanding of contagion beyond the typical notions of infection and pandemics, this book widens the field to include the concept of biosocial epidemics. The chapters propose varied and detailed answers to questions about epidemics and their contagious potential for specific infections and non-infectious conditions. Together they explore how inseparable social and biological processes configure co-existing influences, which create epidemics, and in doing so stress the role of social inequality in these processes. The authors compellingly show that epidemics do not spread evenly in populations or through simple coincidental biological contagion: they are biosocially structured and selective, and happen under specific economic, political and environmental conditions. This volume illustrates that an understanding of biosocial factors is vital for ensuring effective strategies for the containment of epidemics.
Author: Katy Tapper
Publisher: Bloomsbury Publishing
ISBN: 1137579498
Category : Psychology
Languages : en
Pages : 443
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Book Description
This textbook offers a fresh approach to health psychology through the theory and practice of behaviour change. Using an array of case studies from around the world, it discusses how we can develop and evaluate behaviour change interventions. The book encourages active engagement with contemporary discussions about health behaviours, covering areas of emerging importance such as weight stigma, vaping, nudges, vaccine hesitancy and paleo-inspired lifestyles. With a focus upon critical thinking, this book will equip students for success in their research projects and beyond. Ideal for students of Health Behaviour Change and Health Psychology, this textbook is also relevant to those taking courses in related fields such as Nursing and Public Health.
Author: Rida Fatima Saeed
Publisher: Springer Nature
ISBN: 3031556224
Category :
Languages : en
Pages : 309
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Book Description
Author: HK Chopra
Publisher: Jaypee Brothers Medical Publishers
ISBN: 9354653936
Category : Medical
Languages : en
Pages : 981
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Book Description
CVD, or cardiovascular disease, is a general term that describes a disease of the heart or blood vessels. It is one of the most common causes of death. Statins are a group of medicines that can help lower the level of low-density lipoprotein (LDL) cholesterol in the blood. LDL cholesterol of often referred to as ‘bad cholesterol’, and statins reduce its production in the liver. Having a high level of LDL is potentially dangerous as it can lead to hardening and narrowing of the arteries (NHS). Comprising nearly 1000 pages, this book is a comprehensive guide to the latest advances in statin therapy and its clinical application for cardiovascular disease. Divided into 29 sections, the text begins with clinical aspects of CVD, dyslipidemia (the imbalance of lipids such as cholesterol), and the use of statins for treatment. The next sections provide detailed discussion on the use of statins for different types of CVD, including coronary artery disease, hypertension, heart failure, arrhythmia, stroke, and more. The following chapters cover statin use for other systemic diseases such as obesity, kidney disease, diabetes, ocular disorders, skin conditions and many more. The book concludes with an insight into future therapies, with emphasis on PCSK9 inhibitors, a new treatment for lowering cholesterol in the blood.
Author: Andrew J. Dannenberg
Publisher: Springer Science & Business Media
ISBN: 1461468191
Category : Medical
Languages : en
Pages : 440
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Book Description
In addition to its metabolic and endocrinologic effects, obesity and adipose tissue have now been shown to be associated with low grade inflammation resulting in cellular and humoral inflammatory factors of which the latter may act by endocrine, paracrine and autocrine mechanisms. These inflammatory mediators have increasingly been suggested as contributing to the obesity link to carcinogenesis and cancer promotion. This volume of Energy Balance and Cancer will focus on recent developments and cutting edge research pointing to inflammation and inflammatory factors as key mediators of this linkage. The volume first provides information on inflammation as an important link between obesity and insulin resistance, which is in itself linked to promotion of cancer through hyperinsulinemia. The volume then covers some of the most important mechanisms by which obesity leads to inflammation, including the novel inflammasome concept, alterations in chromatin structure, circulating inflammatory factors, unique cellular interactions between adipocytes and macrophages and the direct link of dietary fat to inflammation and cancer. Overall, this volume will provide important insight to help understand how inflammation may help modulate the linkage between obesity and cancer and serve as a platform for developing future research in this area.
Author: Trygve Tollefsbol
Publisher: Academic Press
ISBN: 0128032405
Category : Science
Languages : en
Pages : 944
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Book Description
Medical Epigenetics provides a comprehensive analysis of the importance of epigenetics to health management. The purpose of this book is to fill a current need for a comprehensive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic diseases that affect these systems and modes of treating epigenetic-based disorders and diseases. The intent of this book is to provide a stand-alone comprehensive volume that will cover all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. The overall goal is to provide the leading book on medical epigenetics that will be useful not only to physicians, nurses, medical students and many others directly involved with health care, but also investigators in life sciences, biotech companies, graduate students and many others who are interested in more applied aspects of epigenetics. Research in the area of translational epigenetics is a cornerstone of this volume. Critical reviews dedicated to the burgeoning role of epigenetics in medical practice Coverage of emerging topics including twin epigenetics as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine Encompasses a disease-oriented perspective of medical epigenetics as well as diagnostic and prognostic epigenetic approaches to applied medicine
