Molecular Methods for Evolutionary Genetics PDF Download
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Author: Virginie Orgogozo
Publisher: Humana Press
ISBN: 9781617792274
Category : Medical
Languages : en
Pages : 503
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Book Description
We are entering a particularly fruitful period in evolutionary genetics, as rapid technological progress transforms the investigation of genetic variation within and between species. Molecular Methods for Evolutionary Genetics is a collection of advanced molecular biology protocols and general overviews intended to represent the essential methods currently bringing evolutionary genetics to fruition. Divided into six thematic sections, this volume covers methods for characterizing genomes, diverse approaches to enrich DNA for subsets of the genome prior to sequencing, and state-of-the-art protocols for sampling genetic variation for genetic mapping studies and population genetic studies (RAD sequencing, Sequenom, microarrays, etc.). The volume concludes by focusing on methods to study candidate genes, from obtaining their sequences and analyzing their transcripts to experimentally manipulating their activities in vivo. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Molecular Methods for Evolutionary Genetics serves as a rich resource to biologists interested in evolution, whether they be specialists or beginners in molecular biology.
Author: Virginie Orgogozo
Publisher: Humana Press
ISBN: 9781617792274
Category : Medical
Languages : en
Pages : 503
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Book Description
We are entering a particularly fruitful period in evolutionary genetics, as rapid technological progress transforms the investigation of genetic variation within and between species. Molecular Methods for Evolutionary Genetics is a collection of advanced molecular biology protocols and general overviews intended to represent the essential methods currently bringing evolutionary genetics to fruition. Divided into six thematic sections, this volume covers methods for characterizing genomes, diverse approaches to enrich DNA for subsets of the genome prior to sequencing, and state-of-the-art protocols for sampling genetic variation for genetic mapping studies and population genetic studies (RAD sequencing, Sequenom, microarrays, etc.). The volume concludes by focusing on methods to study candidate genes, from obtaining their sequences and analyzing their transcripts to experimentally manipulating their activities in vivo. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Molecular Methods for Evolutionary Genetics serves as a rich resource to biologists interested in evolution, whether they be specialists or beginners in molecular biology.
Author: Michele Walters
Publisher: Springer
ISBN: 3319272888
Category : Science
Languages : en
Pages : 330
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Book Description
Biodiversity observation systems are almost everywhere inadequate to meet local, national and international (treaty) obligations. As a result of alarmingly rapid declines in biodiversity in the modern era, there is a strong, worldwide desire to upgrade our monitoring systems, but little clarity on what is actually needed and how it can be assembled from the elements which are already present. This book intends to provide practical guidance to broadly-defined biodiversity observation networks at all scales, but predominantly the national scale and higher. This is a practical how-to book with substantial policy relevance. It will mostly be used by technical specialists with a responsibility for biodiversity monitoring to establish and refine their systems. It is written at a technical level, but one that is not discipline-bound: it should be intelligible to anyone in the broad field with a tertiary education.
Author: Mahmut Caliskan
Publisher: BoD – Books on Demand
ISBN: 9535120425
Category : Science
Languages : en
Pages : 222
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Book Description
In the last 50 years, combinations of conventional and molecular methods have made the genetic diversity a widespread science. Moreover, the issue of conserving genetic diversity as a component of the conservation of the environment has been raised at an international level. We hope that the current book will provide a glimpse into the dynamic process of genetic diversity by presenting the research of some of the scientists who are engaged in development of new tools and ideas in genetic diversity. We would like to express our deepest gratitude to all authors who contributed to this book by sharing their valuable works with us.
Author: M. R. Ahuja
Publisher: Springer
ISBN: 3319256378
Category : Science
Languages : en
Pages : 327
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Book Description
Genetic erosion is the loss of genetic diversity within a species. It can happen very quickly, due to catastrophic events, or changes in land use leading to habitat loss. But it can also occur more gradually and remain unnoticed for a long time. One of the main causes of genetic erosion is the replacement of local varieties by modern varieties. Other causes include environmental degradation, urbanization, and land clearing through deforestation and brush fires. In order to conserve biodiversity in plants, it is important to targets three independent levels that include ecosystems, species and genes. Genetic diversity is important to a species’ fitness, long-term viability, and ability to adapt to changing environmental conditions. Chapters in this book are written by leading geneticists, molecular biologists and other specialists on relevant topics on genetic erosion and conservation genetic diversity in plants. This divisible set of two volumes deals with a broad spectrum of topics on genetic erosion, and approaches to biodiversity conservation in crop plants and trees. Volume 1 deals with indicators and prevention of genetic erosion, while volume 2 covers genetic diversity and erosion in a number of plants species. These two volumes will also be useful to botanists, biotechnologists, environmentalists, policy makers, conservationists, and NGOs working to manage genetic erosion and biodiversity.
Author: Barbara H. Iglewski
Publisher: Elsevier
ISBN: 0323148670
Category : Science
Languages : en
Pages : 486
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Book Description
Molecular Basis of Bacterial Pathogenesis focuses on the molecular mechanism of disease associated with bacterial pathogens. Topics covered include the population genetics of bacterial pathogenesis; environmental modulation of gene expression in gram-negative pathogens; and bacterial invasion and intracellular growth. Bacterial toxins are also discussed. This volume is comprised of 20 chapters and begins with an overview of pathogenesis, paying particular attention to common elements and genetic mechanisms of regulation. The discovery that many bacterial pathogens are clonal, with individual clones often having a greater virulence than others, is then considered. The next section deals with the regulation of synthesis of surface components and their role in colonization of the host and/or evasion of the host immune defense systems; antigenic variation and its role in evasion of the host immune response; and the role of iron acquisition systems in the colonization of the host. Subsequent chapters explore the invasion and intracellular growth of facultative and obligate intracellular parasites. The last section is devoted to studies on the role of bacterial toxic products in pathogenesis. Bacterial lipopolysaccharides (endotoxins) and exotoxins are described. This book should be of interest to molecular biologists, physiologists, clinical specialists, pathologists, and geneticists.
Author: Richard Frankham
Publisher: Oxford University Press
ISBN: 0198783396
Category : Biodiversity
Languages : en
Pages : 426
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Book Description
One of the greatest unmet challenges in conservation biology is the genetic management of fragmented populations of threatened animal and plant species. More than a million small, isolated, population fragments of threatened species are likely suffering inbreeding depression and loss of evolutionary potential, resulting in elevated extinction risks. Although these effects can often be reversed by re-establishing gene flow between population fragments, managers very rarely do this. On the contrary, genetic methods are used mainly to document genetic differentiation among populations, with most studies concluding that genetically differentiated populations should be managed separately, thereby isolating them yet further and dooming many to eventual extinction Many small population fragments are going extinct principally for genetic reasons. Although the rapidly advancing field of molecular genetics is continually providing new tools to measure the extent of population fragmentation and its genetic consequences, adequate guidance on how to use these data for effective conservation is still lacking. This accessible, authoritative text is aimed at senior undergraduate and graduate students interested in conservation biology, conservation genetics, and wildlife management. It will also be of particular relevance to conservation practitioners and natural resource managers, as well as a broader academic audience of conservation biologists and evolutionary ecologists.
Author: A. Karp
Publisher: Bioversity International
ISBN: 929043323X
Category : Germplasm resources, Plant
Languages : en
Pages : 47
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Book Description
Proceedings of a workshop on the use of molecular techniques in the conservation of plant genetic resources.
Author: Fred W. Allendorf
Publisher: John Wiley & Sons
ISBN: 1444309056
Category : Science
Languages : en
Pages : 664
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Book Description
Conservation and the Genetics of Populations gives acomprehensive overview of the essential background, concepts, andtools needed to understand how genetic information can be used todevelop conservation plans for species threatened withextinction. Provides a thorough understanding of the genetic basis ofbiological problems in conservation. Uses a balance of data and theory, and basic and appliedresearch, with examples taken from both the animal and plantkingdoms. An associated website contains example data sets and softwareprograms to illustrate population genetic processes and methods ofdata analysis. Discussion questions and problems are included at the end ofeach chapter to aid understanding. Features Guest Boxes written by leading people in the fieldincluding James F. Crow, Nancy FitzSimmons, Robert C. Lacy, MichaelW. Nachman, Michael E. Soule, Andrea Taylor, Loren H. Rieseberg,R.C. Vrijenhoek, Lisette Waits, Robin S. Waples and AndrewYoung. Supplementary information designed to support Conservationand the Genetics of Populations including: Downloadable sample chapter Answers to questions and problems Data sets illustrating problems from the book Data analysis software programs Website links An Instructor manual CD-ROM for this title is available. Pleasecontact our Higher Education team at ahref="mailto:
[email protected]"
[email protected]/afor more information.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309264944
Category : Technology & Engineering
Languages : en
Pages : 399
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Book Description
Using Science to Improve the BLM Wild Horse and Burro Program: A Way Forward reviews the science that underpins the Bureau of Land Management's oversight of free-ranging horses and burros on federal public lands in the western United States, concluding that constructive changes could be implemented. The Wild Horse and Burro Program has not used scientifically rigorous methods to estimate the population sizes of horses and burros, to model the effects of management actions on the animals, or to assess the availability and use of forage on rangelands. Evidence suggests that horse populations are growing by 15 to 20 percent each year, a level that is unsustainable for maintaining healthy horse populations as well as healthy ecosystems. Promising fertility-control methods are available to help limit this population growth, however. In addition, science-based methods exist for improving population estimates, predicting the effects of management practices in order to maintain genetically diverse, healthy populations, and estimating the productivity of rangelands. Greater transparency in how science-based methods are used to inform management decisions may help increase public confidence in the Wild Horse and Burro Program.
Author: Kenneth M. Weiss
Publisher: Cambridge University Press
ISBN: 9780521336604
Category : Medical
Languages : en
Pages : 384
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Book Description
Recent developments in molecular and computational methods have made it possible to identify the genetic basis of any biological trait, and have led to spectacular advances in the study of human disease. This book provides an overview of the concepts and methods needed to understand the genetic basis of biological traits, including disease, in humans. Using examples of qualitative and quantitative phenotypes, Professor Weiss shows how genetic variation may be quantified, and how relationships between genotype and phenotype may be inferred. This book will appeal to many biologists and biological anthropologists interested in the genetic basis of biological traits, as well as to epidemiologists, biomedical scientists, human geneticists and molecular biologists.
