An Introduction to Molecular Anthropology

An Introduction to Molecular Anthropology PDF Author: Mark Stoneking
Publisher: John Wiley & Sons
ISBN: 1118061624
Category : Science
Languages : en
Pages : 396

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Book Description
Molecular anthropology uses molecular genetic methods to address questions and issues of anthropological interest. More specifically, molecular anthropology is concerned with genetic evidence concerning human origins, migrations, and population relationships, including related topics such as the role of recent natural selection in human population differentiation, or the impact of particular social systems on patterns of human genetic variation. Organized into three major sections, An Introduction to Molecular Anthropology first covers the basics of genetics – what genes are, what they do, and how they do it – as well as how genes behave in populations and how evolution influences them. The following section provides an overview of the different kinds of genetic variation in humans, and how this variation is analyzed and used to make evolutionary inferences. The third section concludes with a presentation of the current state of genetic evidence for human origins, the spread of humans around the world, the role of selection and adaptation in human evolution, and the impact of culture on human genetic variation. A final, concluding chapter discusses various aspects of molecular anthropology in the genomics era, including personal ancestry testing and personal genomics. An Introduction to Molecular Anthropology is an invaluable resource for students studying human evolution, biological anthropology, or molecular anthropology, as well as a reference for anthropologists and anyone else interested in the genetic history of humans.

An Introduction to Molecular Anthropology

An Introduction to Molecular Anthropology PDF Author: Mark Stoneking
Publisher: John Wiley & Sons
ISBN: 1118061624
Category : Science
Languages : en
Pages : 396

Get Book Here

Book Description
Molecular anthropology uses molecular genetic methods to address questions and issues of anthropological interest. More specifically, molecular anthropology is concerned with genetic evidence concerning human origins, migrations, and population relationships, including related topics such as the role of recent natural selection in human population differentiation, or the impact of particular social systems on patterns of human genetic variation. Organized into three major sections, An Introduction to Molecular Anthropology first covers the basics of genetics – what genes are, what they do, and how they do it – as well as how genes behave in populations and how evolution influences them. The following section provides an overview of the different kinds of genetic variation in humans, and how this variation is analyzed and used to make evolutionary inferences. The third section concludes with a presentation of the current state of genetic evidence for human origins, the spread of humans around the world, the role of selection and adaptation in human evolution, and the impact of culture on human genetic variation. A final, concluding chapter discusses various aspects of molecular anthropology in the genomics era, including personal ancestry testing and personal genomics. An Introduction to Molecular Anthropology is an invaluable resource for students studying human evolution, biological anthropology, or molecular anthropology, as well as a reference for anthropologists and anyone else interested in the genetic history of humans.

Molecular Applications in Biological Anthropology

Molecular Applications in Biological Anthropology PDF Author: Eric Jeffrey Devor
Publisher: Cambridge University Press
ISBN: 9780521391092
Category : Science
Languages : en
Pages : 276

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Book Description
This volume presents the findings of a selection of pioneering research studies in which new molecular techniques have been used to address key questions in biological anthropology, for example about the human genetic system, the geographical movements of human populations in the past, and primate evolution.

Anthropological Genetics

Anthropological Genetics PDF Author: Michael H. Crawford
Publisher: Cambridge University Press
ISBN: 9780521546973
Category : Medical
Languages : en
Pages : 492

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Book Description
Volume detailing the effects of the molecular revolution on anthropological genetics and how it redefined the field.

Explorations

Explorations PDF Author: Beth Shook
Publisher:
ISBN: 9781931303637
Category : Biology
Languages : en
Pages : 732

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Book Description
Welcome to Explorations and biological anthropology! An electronic version of this textbook is available free of charge at the Society for Anthropology in Community Colleges' webpage here: www.explorations.americananthro.org

Genetic Variation and Human Disease

Genetic Variation and Human Disease PDF Author: Kenneth M. Weiss
Publisher: Cambridge University Press
ISBN: 9780521336604
Category : Medical
Languages : en
Pages : 384

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Book Description
Recent developments in molecular and computational methods have made it possible to identify the genetic basis of any biological trait, and have led to spectacular advances in the study of human disease. This book provides an overview of the concepts and methods needed to understand the genetic basis of biological traits, including disease, in humans. Using examples of qualitative and quantitative phenotypes, Professor Weiss shows how genetic variation may be quantified, and how relationships between genotype and phenotype may be inferred. This book will appeal to many biologists and biological anthropologists interested in the genetic basis of biological traits, as well as to epidemiologists, biomedical scientists, human geneticists and molecular biologists.

Biological Anthropology

Biological Anthropology PDF Author: Noel Thomas Boaz
Publisher:
ISBN: 9780130908193
Category : Human evolution
Languages : en
Pages : 0

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Book Description
This new edition ofBiological Anthropology is evolutionary in perspective in the belief that evolution is the only unifying theory that can clearly explain the existing array of biological and cultural data. The basics of anthropological theory and human genetics are introduced before the topics of vertebrate evolution, primate evolution and social behavior, human evolution and behavior, and human variation and adaptation. In each section, behavior, morphology, adaptation, and ecology are discussed to provide the comparative basis for human origins. Includes expanded sections on genetics, with a new chapter on classic genetics (Ch. 2), and a new chapter on Darwinian evolution (Ch. 3); a new chapter on the living primates, their distribution and anatomical adaptations (Ch. 7); an expanded section onHomo, including a new chapter onHomo sapiens sapiens ; and a new chapter on hominoid and human behavior (Ch. 13), which combines the evolution of hominoid behavior and the evolution of human social behavior.

Forensic DNA Applications

Forensic DNA Applications PDF Author: Dragan Primorac
Publisher: CRC Press
ISBN: 1466580224
Category : Law
Languages : en
Pages : 652

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Book Description
Forensic DNA Applications: An Interdisciplinary Perspective was developed as an outgrowth of a conference held by the International Society of Applied Biological Sciences. The topic was human genome–based applications in forensic science, anthropology, and individualized medicine. Assembling the contributions of contributors from numerous regions around the world, this volume is designed as both a textbook for forensic molecular biology students and a reference for practitioners and those in the legal system. The book begins with the history and development of DNA typing and profiling for criminal and civil purposes. It discusses the statistical interpretation of results with case examples, mitochondrial DNA testing, Y single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs), and X SNP and STR testing. It also explores low copy number DNA typing, mixtures, and quality assurance and control. The second section examines the collection and preservation of biological evidence under a variety of different circumstances and the identification of human remains—including in mass disaster settings. It discusses applications to bioterrorism investigations, animal DNA testing in criminal cases, pedigree questions and wildlife forensic problems, applications in forensic entomology, and forensic botany. The third section explores recent developments and new technologies, including the rigorous identification of tissue of origin, mtDNA profiling using immobilized probe strips, chips and next-generation sequencing, the use of SNPs to ascertain phenotypic characteristics, and the "molecular autopsy" that looks at aspects of toxicogenetics and pharmacogenetics. The book concludes with a discussion on law, ethics, and policy. It examines the use of DNA evidence in the criminal justice system in both the United States and Europe, ethical issues in forensic laboratory practices, familial searches, DNA databases, ancestry searches, physical phenotyping, and report writing. The contributors also examine DNA applications in immigration and human trafficking cases and international perspectives on DNA databases.

Applications of Biological Anthropology to Human Affairs

Applications of Biological Anthropology to Human Affairs PDF Author: C. G. Nicholas Mascie-Taylor
Publisher: Cambridge University Press
ISBN: 9780521019354
Category : Social Science
Languages : en
Pages : 264

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Book Description
The unique contribution made by biological anthropology to human welfare lies in the fundamental understanding it can provide of the dynamic interrelationships between physical and social factors. By understanding these patterns, we can interpret the significance of variation in such measures of human well-being in terms of the incidence of disease and mortality rates. Topics covered in this book include reproductive ecology and fertility, nutritional status in relation to health, and the effects of pollution on individual growth. In later chapters, the concepts of physiological adaptation and Darwinian fitness and their relation to individual physical fitness are explored.

Virtual Anthropology

Virtual Anthropology PDF Author: Gerhard W. Weber
Publisher: Springer Publishing Company
ISBN:
Category : Computers
Languages : en
Pages : 456

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Book Description
This is the first textbook of Virtual Anthropology, the new science that combines elements from fields as diverse as anthropology, medicine, statistics, computing, scientific visualization, and industrial design. The book is intended for students in any of these or nearby fields within biology, medicine, or engineering and for teachers, journalists, and all others who will enjoy the many examples from our real biological world. After a general introduction to the field and an overview, the book is organized around six themes conveyed in more than 300 pages of text accompanied by hundreds of carefully annotated images: medical imaging and 3D digitising techniques, electronic preparation of individual specimens, analysis of complex forms in space one or many at a time, reconstruction of forms that are partly missing or damaged, production of real objects from virtual models, and, finally, thoughts about data accessibility and sharing and the implications of all this for the future of anthropology. The authors' emphasis is not on technical details but rather on step-by-step explanations of the wealth of examples included here, from brain evolution to surgical planning, always in light of the relevance of these approaches to science and to society. All readers are encouraged to try out the techniques on their own using the tools and data included in the Online Extra Materials resource.

Cancer Evolution

Cancer Evolution PDF Author: Charles Swanton
Publisher: Perspectives Cshl
ISBN: 9781621821434
Category : Medical
Languages : en
Pages : 350

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Book Description
Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer.