Modern Therapeutics in Rheumatic Diseases PDF Download
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Author: George C. Tsokos
Publisher: Springer Science & Business Media
ISBN: 1592592392
Category : Medical
Languages : en
Pages : 648
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Book Description
Leading clinicians and clinical researchers discuss in practical detail the newest treatments used in rheumatic diseases, emphasizing-without neglecting current standard treatments-those experimental therapies now undergoing clinical trials and poised for early introduction into the rheumatology armamentarium. The diseases and therapeutic regimes examined here range from rheumatoid arthritis and its treatment by gene therapy, to osteoarthritis and systemic autoimune diseases. Each chapter is organized so that the busy clinician can quickly obtain all the information needed optimal patient treatment. This includes an analysis of the pathogenic mechanisms that explain the molecular basis of the newer therapeutics, reviews of animal data and the results of clinical trials, and recommendations concerning use, side effects, and precautions.
Author: George C. Tsokos
Publisher: Springer Science & Business Media
ISBN: 1592592392
Category : Medical
Languages : en
Pages : 648
Get Book Here
Book Description
Leading clinicians and clinical researchers discuss in practical detail the newest treatments used in rheumatic diseases, emphasizing-without neglecting current standard treatments-those experimental therapies now undergoing clinical trials and poised for early introduction into the rheumatology armamentarium. The diseases and therapeutic regimes examined here range from rheumatoid arthritis and its treatment by gene therapy, to osteoarthritis and systemic autoimune diseases. Each chapter is organized so that the busy clinician can quickly obtain all the information needed optimal patient treatment. This includes an analysis of the pathogenic mechanisms that explain the molecular basis of the newer therapeutics, reviews of animal data and the results of clinical trials, and recommendations concerning use, side effects, and precautions.
Author: George C. Tsokos
Publisher: Springer Science & Business Media
ISBN:
Category : Health & Fitness
Languages : en
Pages : 680
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Book Description
Leading clinicians and clinical researchers discuss in practical detail the newest treatments used in rheumatic diseases, emphasizing-without neglecting current standard treatments-those experimental therapies now undergoing clinical trials and poised for early introduction into the rheumatology armamentarium. The diseases and therapeutic regimes examined here range from rheumatoid arthritis and its treatment by gene therapy, to osteoarthritis and systemic autoimune diseases. Each chapter is organized so that the busy clinician can quickly obtain all the information needed optimal patient treatment. This includes an analysis of the pathogenic mechanisms that explain the molecular basis of the newer therapeutics, reviews of animal data and the results of clinical trials, and recommendations concerning use, side effects, and precautions.
Author: George Henry Napheys
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 624
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Book Description
Author: Richard K. Burt
Publisher: CRC Press
ISBN: 1000724670
Category : Medical
Languages : en
Pages : 1406
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Book Description
Stem cell transplantation may be complicated by treatment-related mortality and like the immune system that it regenerates has equal potential to either create and preserve or destroy. The dual nature that defines stem cells is differentiation that ultimately leads to death and self-renewal, which leads to immortality. What types of stem cells are there? How are they collected? What are their attributes and characteristics? This textbook devotes many chapters to familiarize the reader with the basic science, clinical aspects, and new questions being raised in the field of stem cell biology. Blood stem cells for tolerance and tissue regeneration are a rapidly developing research and clinical field that is being applied to autoimmune diseases. In clinical trials, autologous hematopoietic (blood) stem cells are being used to reduce the cytopenic interval following intense immune suppressive transplant regimens. While as yet not delineated, some possible mechanisms and pathways leading to tolerance after hematopoietic stem cell transplantation are suggested in these chapters. Tissue regeneration from blood stem cells is also suggested by animal experiments on stem cell plasticity or metamoirosis (i.e., change in fate) as described within this textbook. Ongoing early clinical trials on tissue regeneration from blood stem cells are described in the chapter on stem cell therapy for cardiac and peripheral vascular disease. Whether autologous hematopoietic stem cells, through the process of mobilization and reinfusion, may be manipulated to contribute to tissue repair in autoimmune diseases is a future area for translational research.
Author: Daniel Aletaha
Publisher: Elsevier Health Sciences
ISBN: 0323678971
Category : Medical
Languages : en
Pages :
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Book Description
Guest edited by Dr. Daniel Aletaha, this issue of Rheumatic Disease Clinics will cover “Treat to Target in Rheumatic Diseases with a focus on rationale and results. This issue is one of four selected each year by our series Consulting Editor, Dr. Michael Weisman. Articles explore diseases, including, but not limited to: History, Rheumatoid Arthritis, Psoriatic Arthritis, Spondylarthropathies, Systemic lupus erythematosus, PMR and GCA, Inflammatory Myopathies (PM/DM), Gout, and Subclinical Targets.
Author: Lisa K. Minor
Publisher: CRC Press
ISBN: 1420015702
Category : Medical
Languages : en
Pages : 490
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Book Description
The Handbook of Assay Development in Drug Discovery describes all the tools currently available for performing various assay techniques. Featuring troubleshooting advice for common problems from experienced assay developers, the vendor community, and scientists in the pharmaceutical industry, the book presents descriptions of methods, laboratory guidelines and protocols used to perform such methods, specific examples of each assay system, and troubleshooting tools. Designed as a guide to running an assay from start to finish, this is an ideal bench top companion for scientists involved in drug discovery screening, lead profiling, therapeutic target evaluation, and assay development and implementation.
Author: Daniel Jeffrey Wallace
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781793940
Category : Medical
Languages : en
Pages : 1516
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Book Description
Established for forty years as the definitive reference on lupus, Dubois' Lupus Erythematosus is now in its thoroughly revised, updated Seventh Edition. More than ninety distinguished contributing authors—twenty of them new to this edition—provide comprehensive coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. This edition focuses on evidence-based findings, treatment consensuses, and practical clinical information. New chapters cover cytokines and interferons, pathogenesis of atherosclerosis, immune tolerance, clinical indices in assessment of lupus, mixed connective tissue disease, reproductive issues, fibromyalgia, gender-related issues, and biomarkers.
Author: Maurice L. Tainter
Publisher:
ISBN:
Category : Aspirin
Languages : en
Pages : 144
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Book Description
Author: Bharat B Aggarwal
Publisher: World Scientific
ISBN: 9814468959
Category : Technology & Engineering
Languages : en
Pages : 457
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Book Description
Most therapeutics available today are highly toxic, very expensive and exhibit minimum efficacy. The issue of toxicity is even more critical for prevention than for therapy because the former involves normal subjects. Thus, therapeutics that are safe and affordable are needed for both prevention and therapy. Spices of Southeast Asian origin, once employed for taste, appearance and preservation of food, now appear to have therapeutic value for humans. What the active principles in these spices are and how they mediate their effect against various diseases are beginning to emerge from extensive research carried out within the last half-century. The current monograph is an attempt to address the active constituents, their molecular targets and the therapeutic uses of these spices.
Author: William N. Taylor, M.D.
Publisher: McFarland
ISBN: 0786412410
Category : Social Science
Languages : en
Pages : 351
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Book Description
Anabolic therapies have been found to be useful in the treatment of numerous diseases and conditions and their medical uses continue to expand. This work is a technical and comprehensive study of anabolic therapy, covering a wide range of diseases and conditions. Beginning with a description of anabolic agents and their historical medicinal use, the author provides a rationale for the use of anabolics in treating sarcopenia, CST-induced and postmenopausal osteoporosis, hormone replacement therapy in women, osteoporosis and andropause in men; the autoimmune diseases ALS, Chronic Fatigue Syndrome, MS, rheumatoid arthritis, Sjogren's Syndrome, systemic lupus erythematosus, and systemic sclerosis; stroke treatment and rehabilitation, Type II diabetes in men, and AIDS. Also provided is rationale for the use of anabolic therapies in addition to cancer therapy in cardiopulmonary rehabilitation, spinal cord injuries and other conditions with secondary hypogonadism, dementia, Alzheimer's, depression, and other CNS conditions, musculoskeletal conditions, major burns, wound healing, and the use of anabolic therapies in addition to TPN and nutrition in microgravity, prolonged immobilization, and space travel conditions, chronic anemias, and related conditions.
