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Author: Lars Kaestner
Publisher: Springer
ISBN: 3319953044
Category : Science
Languages : en
Pages : 135
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Book Description
This book provides in depths information on different microscopy approaches and supplies the reader with methods how to untangle highly complex processes involved in physiological and pathophysiological cardiac signaling. Microscopy approaches have established themselves as the quasi gold standard that enables us to appreciate the underlying mechanisms of physiological and pathophysiological cardiac signaling. This book presents the most important microscopy techniques from the level of individual molecule e.g. Förster-Resonance Energy Transfer (FRET), up to cellular and tissue imaging, e.g. electron microscopy (TEM) or light sheet microscopy. The book is intended for graduate students and postdocs in cardiovascular research, imaging and cell biology, pre-clinical and clinical researchers in cardiovascular sciences as well as decision makers of the pharmaceutical industry.
Author: Lars Kaestner
Publisher: Springer
ISBN: 3319953044
Category : Science
Languages : en
Pages : 135
Get Book Here
Book Description
This book provides in depths information on different microscopy approaches and supplies the reader with methods how to untangle highly complex processes involved in physiological and pathophysiological cardiac signaling. Microscopy approaches have established themselves as the quasi gold standard that enables us to appreciate the underlying mechanisms of physiological and pathophysiological cardiac signaling. This book presents the most important microscopy techniques from the level of individual molecule e.g. Förster-Resonance Energy Transfer (FRET), up to cellular and tissue imaging, e.g. electron microscopy (TEM) or light sheet microscopy. The book is intended for graduate students and postdocs in cardiovascular research, imaging and cell biology, pre-clinical and clinical researchers in cardiovascular sciences as well as decision makers of the pharmaceutical industry.
Author: Michael T. Ashworth
Publisher: Cambridge University Press
ISBN: 1107116287
Category : Family & Relationships
Languages : en
Pages : 361
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Book Description
Clearly presents the pathology of heart disease from fetus to adolescence, integrating histology and macroscopy with effects of treatment.
Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 0470868031
Category : Medical
Languages : en
Pages : 300
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Book Description
The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause of cardiac conduction disturbance, arrhythmias and sudden cardiac death. A wealth of information has been collected over many years on the unique histological, morphological and phenotypic characteristics of specialized cardiac tissues. The cellular and molecular mechanisms that govern development of the PCS are now starting to be understood. This book draws together contributions from an international and interdisciplinary group of experts working on both basic and clinical aspects of cardiac development. It features reviews of the structure and function of the developing PCS, discussion of the molecular and cellular mechanisms regulating embryological development of this system and studies on the fundamental basis of PCS pathology. The book also considers how novel therapeutic interventions based on understanding of the developmental biology of cardiac pacemaking and conduction tissues might ultimately impact on clinical medicine.
Author: Institute of Laboratory Animal Resources (U.S.)
Publisher:
ISBN:
Category : Electronic journals
Languages : en
Pages : 510
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Book Description
Author: Sian E. Harding
Publisher: MIT Press
ISBN: 0262548410
Category : Medical
Languages : en
Pages : 234
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Book Description
How science is opening up the mysteries of the heart, revealing the poetry in motion within the machine. Your heart is a miracle in motion, a marvel of construction unsurpassed by any human-made creation. It beats 100,000 times every day—if you were to live to 100, that would be more than 3 billion beats across your lifespan. Despite decades of effort in labs all over the world, we have not yet been able to replicate the heart’s perfect engineering. But, as Sian Harding shows us in The Exquisite Machine, new scientific developments are opening up the mysteries of the heart. And this explosion of new science—ultrafast imaging, gene editing, stem cells, artificial intelligence, and advanced sub-light microscopy—has crucial, real-world consequences for health and well-being. Harding—a world leader in cardiac research—explores the relation between the emotions and heart function, reporting that the heart not only responds to our emotions, it creates them as well. The condition known as Broken Heart Syndrome, for example, is a real disorder than can follow bereavement or stress. The Exquisite Machine describes the evolutionary forces that have shaped the heart’s response to damage, the astonishing rejuvenating power of stem cells, how we can avoid heart disease, and why it can be so hard to repair a damaged heart. It tells the stories of patients who have had the devastating experiences of a heart attack, chaotic heart rhythms, or stress-induced acute heart failure. And it describes how cutting-edge technologies are enabling experiments and clinical trials that will lead us to new solutions to the worldwide scourge of heart disease.
Author: Elisabeth Ehler
Publisher: Springer
ISBN: 3319152637
Category : Science
Languages : en
Pages : 320
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Book Description
This book presents a collection of expert reviews on different subcellular compartments of the cardiomyocyte, addressing fundamental questions such as how these compartments are assembled during development, how they are changed in and by disease and which signaling pathways have been implicated in these processes so far. As such, it offers the first overview of the cell biology of heart disease of its kind, addressing the needs of cell biology students specializing in vascular and cardiac biology, as well as those of cardiologists and researchers in the field of cell biology.
Author: Radivoj V. Krstić
Publisher: Springer Science & Business Media
ISBN: 9783540536666
Category : Medical
Languages : en
Pages : 636
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Book Description
The author, R.V. Krstic, is well-known internationally for his excellent histological drawings. This atlas is an excellent supplement to conventional histology textbooks, for students, teachers and professionals alike.
Author: Yasuo Harada
Publisher: Springer Science & Business Media
ISBN: 9400965982
Category : Medical
Languages : en
Pages : 238
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Book Description
The physiology of the semicircular canals was my main research interest before I began to study their morphology. In 1966, by utilizing the isolated semicircular canal of the frog, I was able to show that cell activity in the horizontal semicircular canal has the opposite polarity to that in the vertical canals, which was the first physiological proof of Ewald's law. Several transmitting electron microscope (TEM) studies had already reported on the morphology of the semicircular canal cristae; however, my morphological work was motivated by a strong desire to see whether the morphological polarity accorded to the physio logical polarity. In 1968 I happened to see the paper written by Dr David Lim, one of my close friends. His findings concerning the vestibular morphology, when examined by scanning electron microscopy (SEM), fascinated me a great deal because of the three-dimensional quality of the micro graphs. This stimulated me to become involved in vestibular morphol ogy. In the beginning, however, I faced many problems with specimen preparation for SEM, and the first few years were spent simply solving technical problems, especially those of artifacts. Many of the figures in this book have been photographed with a JEOL JSM U-3 scanning electron microscope over a decade. The sharpness of these pictures still, I think, bears comparison to the defi nition of those taken by the more sophisticated SEM scopes currently available.
Author: E.S. Hafez
Publisher: Springer Science & Business Media
ISBN: 9401181403
Category : Medical
Languages : en
Pages : 337
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Book Description
The suggestion of Max Knoll that an electron fascinated by the numerous SEM photographs, the wealth of information and the enthusiasm of the microscope could be developed using a fine scanning researchers covering a variety of disciplines. All aspects beam of electrons on a specimen surface and recording the emitted current as a function of the position of the of the female and male genital tract have been covered, beam was launched in 1935. Since then several culminating in the prizewinning award showing the in investigators and clinicians have used this concept to vitro fertilized human egg. develop techniques now known as scanning electron In clinical diagnostics SEM also proved to be a microscopy (SEM) and scanning transmission electron valuable complementary technique, shedding new light microscopy (STEM). The choice to study the female on oncology, the pathogenesis of tubal disease and the reproductive organs was a logical one because cells and maturation process of the placenta. Future research has tissue samples can be sampled relatively easily; still to be accomplished; e.g. quantification of SEM furthermore, these cells and organs are influenced photographs for meaningful and sound biological, continuously by the cyclic production of hormones. scientific and statistical evaluation in diagnostic This atlas demonstrates the state of the art in 1983. gynecology, obstetrics, andrology and oncology.
Author: Florin Mihail Filipoiu
Publisher: Springer Science & Business Media
ISBN: 1447153820
Category : Medical
Languages : en
Pages : 254
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Book Description
This heart anatomy book describes the cardiac development and cardiac anatomy in the development of the adult heart, and is illustrated by numerous images and examples. It contains 550 images of dissected embryo and adult hearts, obtained through the dissection and photography of 235 hearts. It has been designed to allow the rapid understanding of the key concepts and that everything should be clearly and graphically explained in one book. This is an atlas of cardiac development and anatomy of the human heart which distinguishes itself with the use of 550 images of embryonic, fetal and adult hearts and using text that is logical and concise. All the mentioned anatomical structures are shown with the use of suggestive dissection images to emphasize the details and the overall location. All the images have detailed comments, while clinical implications are suggested. The dissections of different hearts exemplify the variability of the cardiac structures. The electron and optical microscopy images are sharp and provide great fidelity. The arterial molds obtained using methyl methacrylate are illustrative and the pictures use suggestive angles. The dissections were made on human normal and pathological hearts of different ages, increasing the clinical utility of the material contained within.
