Microfluidic Point-of-care Diagnostics for Global Health

Microfluidic Point-of-care Diagnostics for Global Health PDF Author: Max Mingxin Gong
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Microfluidic Point-of-care Diagnostics for Global Health

Microfluidic Point-of-care Diagnostics for Global Health PDF Author: Max Mingxin Gong
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Paper Microfluidics

Paper Microfluidics PDF Author: Shantanu Bhattacharya
Publisher: Springer Nature
ISBN: 981150489X
Category : Medical
Languages : en
Pages : 225

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Book Description
This volume provides an overview of the recent advances in the field of paper microfluidics, whose innumerable research domains have stimulated considerable efforts to the development of rapid, cost-effective and simplified point-of-care diagnostic systems. The book is divided into three parts viz. theoretical background of paper microfluidics, fabrication techniques for paper-based devices, and broad applications. Each chapter of the book is self-explanatory and focuses on a specific topic and its relation to paper microfluidics and starts with a brief description of the topic’s physical background, essential definitions, and a short story of the recent progress in the relevant field. The book also covers the future outlook, remaining challenges, and emerging opportunities. This book shall be a tremendous up-to-date resource for researchers working in the area globally.

Advanced Microfluidics Based Point-of-Care Diagnostics

Advanced Microfluidics Based Point-of-Care Diagnostics PDF Author: Raju Khan
Publisher: CRC Press
ISBN: 1000548376
Category : Medical
Languages : en
Pages : 416

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Book Description
This book provides a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. This authors examine microfluidics based diagnosis in the biomedical field as an upcoming field with extensive applications. It provides a unique approach and comprehensive technology overview for diagnosis management towards early stages of various bioanalytes via cancer diagnostics diabetes, alzheimer disease, toxicity in food products, brain and retinal diseases, cardiovascular diseases, and bacterial infections etc. Thus, this book would encompass a combinatorial approach of medical science, engineering and biomedical technology. The authors provide a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. Moreover, this book contains detailed description on the diagnosis of novel techniques. This book would serve as a guide for students, scientists, researchers, and microfluidics based point of care technologies via smart diagnostics and to plan future research in this valuable field.

Diagnostic Devices with Microfluidics

Diagnostic Devices with Microfluidics PDF Author: Francesco Piraino
Publisher: CRC Press
ISBN: 1498772943
Category : Medical
Languages : en
Pages : 281

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Book Description
Focuses specifically on diagnostic applications. Explores the commercial aspects of developing microfluidic diagnostic device. Highlights the growing field and presents a selection of important topics making it an excellent introductory reading for graduate students in bioengineering and related disciplines. Teaches the reader how to fabricate, apply, and market microfludic diagnostic chips for lab and at home use. Discusses patient-focused development of diagnostics devices.

Advanced Microfluidics Based Point-Of-Care Diagnostics

Advanced Microfluidics Based Point-Of-Care Diagnostics PDF Author: Raju Khan
Publisher:
ISBN: 9781032218120
Category : Medical
Languages : en
Pages : 0

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Book Description
"This book provides a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. Moreover, i also contains detailed descriptions on the diagnosis of novel techniques"--

Microfluidic Technologies for Human Health

Microfluidic Technologies for Human Health PDF Author: Utkan Demirci
Publisher: World Scientific
ISBN: 9814405515
Category : Medical
Languages : en
Pages : 495

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Book Description
Ch. 1. A microscale bioinspired cochlear-like sensor / Robert D. White, Robert Littrell, and Karl Grosh -- ch. 2. Systematic evaluation of the efficiencies of proteins and chemicals in pharmaceutical applications / Morgan Hamon and Jong Wook Hong -- ch. 3. Microfluidic glucose sensors / Jithesh V. Veetil [und weitere] -- ch. 4. Applications of microfabrication and microfluidic techniques in mesenchymal stem cell research / Abhijit Majumder [und weitere] -- ch. 5. Patient-specific modeling of low-density lipoprotein transport in coronary arteries / Ufuk Olgac -- ch. 6. Point-of-care microdevices for global health diagnostics of infectious diseases / Sau Yin Chin [und weitere] -- ch. 7. Integrated microfluidic sample preparation for chip-based molecular diagnostics / Jane Y. Zhang [und weitere] -- ch. 8. Microfluidic devices for cellular proteomic studies / Yihong Zhan and Chang Lu -- ch. 9. Microfluidics for neuroscience: novel tools and future implications / Vivian M. Hernandez and P. Hande Ozdinler -- ch. 10. Microfluidics: on-chip platforms as in vitro disease models / Shan Gao, Erkin Seker, and Martin L. Yarmush -- ch. 11. Application of microfluidics in stem cell and tissue engineering / Sasha H. Bakhru, Christopher Highley, and Stefan Zappe -- ch. 12. Microfluidic "on-the-fly" fabrication of microstructures for biomedical applications / Edward Kang, Sau Fung Wong, and Sang-Hoon Lee -- ch. 13. Microfluidics as a promising tool toward distributed viral detection / Elodie Sollier and Dino Di Carlo -- ch. 14. Electrophoresis and dielectrophoresis for lab-on-a-chip (LOC) analyses / Yagmur Demircan, Gurkan Yilmaz, and Haluk Kulah -- ch. 15. Ultrasonic embossing of carbon nanotubes for the fabrication of polymer microfluidic chips for DNA sample purification / Puttachat Khuntontong, Min Gong, and Zhiping Wang -- ch. 16. Ferrofluidics / A. Rezzan Kose and Hur Koser -- ch. 17. Antibody-based blood bioparticle capture and separation using microfluidics for global health / ZhengYuan Luo [und weitere] -- ch. 18. Applications of quantum dots for fluorescence imaging in biomedical research / ShuQi Wang [und weitere]

Frugal Innovation in Bioengineering for the Detection of Infectious Diseases

Frugal Innovation in Bioengineering for the Detection of Infectious Diseases PDF Author: Arvind K. Chavali
Publisher: Springer
ISBN: 3319666479
Category : Medical
Languages : en
Pages : 129

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Book Description
This book introduces readers to the concept of 'frugal innovation' and describes novel low-cost technologies that aid in diagnosing infectious diseases. Rapidly deployable, portable, and affordable diagnostic tools have the potential to tremendously benefit populations in resource-limited settings and improve global health outcomes. Specifically, the book includes the following features: Cutting-Edge Research: Thorough coverage of scientific advances related to frugal bioengineering that have been developed within the last few years. A few examples of technologies covered in detail include low-cost paper-based and CD-based microfluidic diagnostic systems. Industry and Non-Profit Voices: Chapters written by scientists currently working in industry and philanthropic sectors.

A Practical Guide to Global Point-of-Care Testing

A Practical Guide to Global Point-of-Care Testing PDF Author: Mark Shephard OAM
Publisher: CSIRO PUBLISHING
ISBN: 1486305202
Category : Medical
Languages : en
Pages : 650

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Book Description
Point-of-care testing (POCT) refers to pathology testing performed in a clinical setting at the time of patient consultation, generating a rapid test result that enables informed and timely clinical action to be taken on patient care. It offers patients greater convenience and access to health services and helps to improve clinical outcomes. POCT also provides innovative solutions for the detection and management of chronic, acute and infectious diseases, in settings including family practices, Indigenous medical services, community health facilities, rural and remote areas and in developing countries, where health-care services are often geographically isolated from the nearest pathology laboratory. A Practical Guide to Global Point-of-Care Testing shows health professionals how to set up and manage POCT services under a quality-assured, sustainable, clinically and culturally effective framework, as well as understand the wide global scope and clinical applications of POCT. The book is divided into three major themes: the management of POCT services, a global perspective on the clinical use of POCT, and POCT for specific clinical settings. Chapters within each theme are written by experts and explore wide-ranging topics such as selecting and evaluating devices, POCT for diabetes, coagulation disorders, HIV, malaria and Ebola, and the use of POCT for disaster management and in extreme environments. Figures are included throughout to illustrate the concepts, principles and practice of POCT. Written for a broad range of practicing health professionals from the fields of medical science, health science, nursing, medicine, paramedic science, Indigenous health, public health, pharmacy, aged care and sports medicine, A Practical Guide to Global Point-of-Care Testing will also benefit university students studying these health-related disciplines.

Development of Point-of-care Diagnostic Technologies for Global and Mental Health

Development of Point-of-care Diagnostic Technologies for Global and Mental Health PDF Author: Elizabeth Grace Rey
Publisher:
ISBN:
Category :
Languages : en
Pages : 120

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Book Description
Access to diagnostic testing and screening technologies helps to improve patient care by enabling early treatment and monitoring of patient condition. Most of these technologies, however, rely on laboratory infrastructure and are expensive and time-consuming. In many limited-resource settings, these challenges are too great to overcome, preventing patient access to early diagnosis and screening. Point-of-care diagnostic technologies are designed to fill this need, providing low-cost, easy-to-use, and rapid testing. Lateral flow assays (LFAs) represent a simple platform for biomarker-based point-of-care diagnostics with very low cost and a rapid result. Antigen-antibody binding forms the basis of these tests, with labeled antibodies or proteins typically providing an optical signal that can either be seen by eye or analyzed using imaging devices. Microfluidic assays are another form of biomarker analysis that can be designed to incorporate more complex assays with more steps than a traditional LFA. In this work, we describe our efforts to develop novel and improved immunoassays for use at the point of care based on LFA and microfluidic technologies. The first three chapters of this dissertation describe our work on three different applications of lateral flow technology. We will first discuss our improvements to the detection range of an LFA through periodic measurement of the developing signal and kinetic analysis of the result. This work demonstrated our ability to overcome the high-dose hook effect without altering the LFA or the steps required by the user. Next, we present our point-of-care system for determination of folate status in serum. This technology provides a method for measuring folate concentration in serum without the use of complex technology. Our third lateral flow technology is an LFA to measure cortisol concentration in saliva. This LFA was validated in saliva samples from a human study that analyzed participant alertness and cortisol levels. Our final work describes the design of a microfluidic system for improved sensitivity in measurement of cortisol concentration in saliva. This system incorporates sample collection, filtration, treatment, and transfer to the microfluidic assay. An all-in-one device interacts with a disposable cassette to pump saliva into the microfluidic chip and provide a result.

Point-of-Care Diagnostics on a Chip

Point-of-Care Diagnostics on a Chip PDF Author: David Issadore
Publisher: Springer Science & Business Media
ISBN: 3642292682
Category : Science
Languages : en
Pages : 236

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Book Description
The topic of this book is the development of automated and inexpensive tools that transfer medical tests from a specialized clinical laboratory directly to the point of care, using biochip technology. Immediate access to medically relevant biochemical information for doctors and nurses promises to revolutionize patient care and dramatically lower costs. The miniaturization and automation of medical tests are made possible by biochip technology, that integrates advances in integrated circuits, microelectromechanical systems (MEMS), microfluidics, and electronics. The target audience for this book includes engineering and biomedical researchers who would like to develop or apply biochip technology. They can use this book as a review of the field and as a guide for the development of novel biochip technology for point of care medicine. This book can also be used as a teaching tool for engineering and biomedical students, as well as a reference for physicians and health professionals.