Author: Eric Vittinghoff
Publisher: Springer Science & Business Media
ISBN: 1461413524
Category : Education
Languages : en
Pages : 526
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Book Description
This fresh edition, substantially revised and augmented, provides a unified, in-depth, readable introduction to the multipredictor regression methods most widely used in biostatistics. The examples used, analyzed using Stata, can be applied to other areas.
Author: Mark Chang
Publisher: Springer Science & Business Media
ISBN: 144199842X
Category : Medical
Languages : en
Pages : 316
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Book Description
Classic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics, beyond just a simple application of statistics, is a confluence of statistics and knowledge of multiple intertwined fields. The application demands, the advancements in computer technology, and the rapid growth of life science data (e.g., genomics data) have promoted the formation of modern biostatistics. There are at least three characteristics of modern biostatistics: (1) in-depth engagement in the application fields that require penetration of knowledge across several fields, (2) high-level complexity of data because they are longitudinal, incomplete, or latent because they are heterogeneous due to a mixture of data or experiment types, because of high-dimensionality, which may make meaningful reduction impossible, or because of extremely small or large size; and (3) dynamics, the speed of development in methodology and analyses, has to match the fast growth of data with a constantly changing face. This book is written for researchers, biostatisticians/statisticians, and scientists who are interested in quantitative analyses. The goal is to introduce modern methods in biostatistics and help researchers and students quickly grasp key concepts and methods. Many methods can solve the same problem and many problems can be solved by the same method, which becomes apparent when those topics are discussed in this single volume.
Author: Walter T. Ambrosius
Publisher: Springer Science & Business Media
ISBN: 1588295311
Category : Medical
Languages : en
Pages : 530
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Book Description
This book presents a multidisciplinary survey of biostatics methods, each illustrated with hands-on examples. It introduces advanced methods in statistics, including how to choose and work with statistical packages. Specific topics of interest include microarray analysis, missing data techniques, power and sample size, statistical methods in genetics. The book is an essential resource for researchers at every level of their career.
Author: Wolfgang Härdle
Publisher: Springer Science & Business Media
ISBN: 354032691X
Category : Medical
Languages : en
Pages : 373
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Book Description
This book covers a wide range of recent statistical methods that are of interest to scientists in biostatistics as well as in other related fields such as chemometrics, environmetrics and geophysics. The contributed papers, from internationally recognized researchers, present various statistical methodologies together with a selected scope of their main mathematical properties and their application in a real case study.
Author: P. S. S. SUNDAR RAO
Publisher: PHI Learning Pvt. Ltd.
ISBN: 8120345207
Category : Medical
Languages : en
Pages : 279
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Book Description
The last decade has produced many textbooks on Biostatistics, with varying emphasis and degrees of mathematical complexity. This book has stood the test of time and continues to enjoy wide acceptance among students of all health and allied professions, other students and even qualified health investigators, who find it practical, simple and yet precise. This fully updated and thoroughly revised Fifth Edition, while retaining the fundamental concepts, acquaints the reader with the advances in the subject. The book explains the concepts involved in arriving at the sample size and also a quick solution to the estimation of sample size. Survival analysis and log-rank test are illustrated with examples. The essentials of Chi square tests are simplified and presented. Two-way analysis of variance (ANOVA) is explained with two examples, with and without interaction term. The chapters on Research Methods, Interventional Studies and Observational Studies provide step-by-step guide to plan and carry out quality research. Questions given in each chapter will help the learner to gauge the level of understanding of the principles and applications. Clues to the use of computer packages are provided whenever necessary. Intended for undergraduate and postgraduate medical students as well as for nursing and paramedical students, the book will also be immensely useful to medical/health faculty and researchers in the field of Biostatistics. KEY FEATURES : A new chapter on Sample Size Determination Several new sections Extensive revision of practically all chapters Provision of new examples Chapter-end exercises
Author: John M. Lachin
Publisher: John Wiley & Sons
ISBN: 1118625846
Category : Mathematics
Languages : en
Pages : 676
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Book Description
Praise for the First Edition ". . . an excellent textbook . . . an indispensable reference for biostatisticians and epidemiologists." —International Statistical Institute A new edition of the definitive guide to classical and modern methods of biostatistics Biostatistics consists of various quantitative techniques that are essential to the description and evaluation of relationships among biologic and medical phenomena. Biostatistical Methods: The Assessment of Relative Risks, Second Edition develops basic concepts and derives an expanded array of biostatistical methods through the application of both classical statistical tools and more modern likelihood-based theories. With its fluid and balanced presentation, the book guides readers through the important statistical methods for the assessment of absolute and relative risks in epidemiologic studies and clinical trials with categorical, count, and event-time data. Presenting a broad scope of coverage and the latest research on the topic, the author begins with categorical data analysis methods for cross-sectional, prospective, and retrospective studies of binary, polychotomous, and ordinal data. Subsequent chapters present modern model-based approaches that include unconditional and conditional logistic regression; Poisson and negative binomial models for count data; and the analysis of event-time data including the Cox proportional hazards model and its generalizations. The book now includes an introduction to mixed models with fixed and random effects as well as expanded methods for evaluation of sample size and power. Additional new topics featured in this Second Edition include: Establishing equivalence and non-inferiority Methods for the analysis of polychotomous and ordinal data, including matched data and the Kappa agreement index Multinomial logistic for polychotomous data and proportional odds models for ordinal data Negative binomial models for count data as an alternative to the Poisson model GEE models for the analysis of longitudinal repeated measures and multivariate observations Throughout the book, SAS is utilized to illustrate applications to numerous real-world examples and case studies. A related website features all the data used in examples and problem sets along with the author's SAS routines. Biostatistical Methods, Second Edition is an excellent book for biostatistics courses at the graduate level. It is also an invaluable reference for biostatisticians, applied statisticians, and epidemiologists.
Author: Arun Bhadra Khanal
Publisher: Jaypee Brothers Medical Publishers Pvt. Limited
ISBN: 9789351529095
Category : Medical
Languages : en
Pages : 0
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Book Description
Author: Stephane Heritier
Publisher: John Wiley & Sons
ISBN: 9780470740545
Category : Medical
Languages : en
Pages : 292
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Book Description
Robust statistics is an extension of classical statistics that specifically takes into account the concept that the underlying models used to describe data are only approximate. Its basic philosophy is to produce statistical procedures which are stable when the data do not exactly match the postulated models as it is the case for example with outliers. Robust Methods in Biostatistics proposes robust alternatives to common methods used in statistics in general and in biostatistics in particular and illustrates their use on many biomedical datasets. The methods introduced include robust estimation, testing, model selection, model check and diagnostics. They are developed for the following general classes of models: Linear regression Generalized linear models Linear mixed models Marginal longitudinal data models Cox survival analysis model The methods are introduced both at a theoretical and applied level within the framework of each general class of models, with a particular emphasis put on practical data analysis. This book is of particular use for research students,applied statisticians and practitioners in the health field interested in more stable statistical techniques. An accompanying website provides R code for computing all of the methods described, as well as for analyzing all the datasets used in the book.
Author: Raphael. L.C Araújo
Publisher: Springer
ISBN: 3319713248
Category : Medical
Languages : en
Pages : 348
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Book Description
This book introduces and discusses the most important aspects of clinical research methods and biostatistics for oncologists, pursuing a tailor-made and practical approach. Evidence-based medicine (EBM) has been in vogue in the last few decades, particularly in rapidly advancing fields such as oncology. This approach has been used to support decision-making processes worldwide, sparking new clinical research and guidelines on clinical and surgical oncology. Clinical oncology research has many peculiarities, including specific study endpoints, a special focus on survival analyses, and a unique perspective on EBM. However, during medical studies and in general practice, these topics are barely taught. Moreover, even when EBM and clinical cancer research are discussed, they are presented in a theoretical fashion, mostly focused on formulas and numbers, rather than on clinical application for a proper literature appraisal. Addressing that gap, this book discusses more practical aspects of clinical research and biostatistics in oncology, instead of relying only on mathematical formulas and theoretical considerations. Methods and Biostatistics in Oncology will help readers develop the skills they need to understand the use of research on everyday oncology clinical practice for study design and interpretation, as well to demystify the use of EBM in oncology.
Author: Bernard Rosner
Publisher: Cengage Learning
ISBN: 9781305268920
Category : Mathematics
Languages : en
Pages : 0
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Book Description
Bernard Rosner's FUNDAMENTALS OF BIOSTATISTICS is a practical introduction to the methods, techniques, and computation of statistics with human subjects. It prepares students for their future courses and careers by introducing the statistical methods most often used in medical literature. Rosner minimizes the amount of mathematical formulation (algebra-based) while still giving complete explanations of all the important concepts. As in previous editions, a major strength of this book is that every new concept is developed systematically through completely worked out examples from current medical research problems. Most methods are illustrated with specific instructions as to implementation using software either from SAS, Stata, R, Excel or Minitab. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
