Systems Biology PDF Download
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Author: Herbert Sauro
Publisher:
ISBN: 9780982477366
Category : Science
Languages : en
Pages : 278
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Book Description
This book is an introduction to control in biochemical pathways. Itintroduces students to some of the most important concepts in modern metabolic control principles. It covers the basics of metabolic controlanalysis that helps us think about how biochemical networks operate. The book should be suitable for undergraduates in their early (Junior, USA, second year UK) to mid years at college.
Author: Stephan Herzig
Publisher: Springer
ISBN: 9783319806570
Category : Medical
Languages : en
Pages : 0
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Book Description
The HEP issue on Metabolic Control provides a state-of the art overview over both classical concepts and emerging areas in metabolism and associated disorders. In this context, metabolic control is highlighted at various levels of complexity ranging from transcriptional mechanisms in metabolic pathway control over metabolic communication routes in physiology and pathophysiology to current treatment modalities and options in metabolic disorders, including type 2 diabetes and obesity. Dedicated chapters by leading experts in their fields provide a concise overview over important areas in metabolic research at a molecular level, including the role of the central nervous system in metabolism, inflammation and metabolism, pancreatic hormone signaling, brown adipose tissue, and therapeutic concepts.
Author: Jens Nielsen
Publisher: Springer
ISBN: 3540453008
Category : Science
Languages : en
Pages : 193
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Book Description
Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of Advances in Biochemical Engineering/Biotechnology, developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity - illustrated by amino acid production and the production of novel compounds - in the production of polyketides and extension of the substrate range - and in the engineering of S. cerevisiae for xylose metabolism, and the improvement of a complex biotransformation process.
Author: Herbert Sauro
Publisher:
ISBN: 9780982477366
Category : Science
Languages : en
Pages : 278
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Book Description
This book is an introduction to control in biochemical pathways. Itintroduces students to some of the most important concepts in modern metabolic control principles. It covers the basics of metabolic controlanalysis that helps us think about how biochemical networks operate. The book should be suitable for undergraduates in their early (Junior, USA, second year UK) to mid years at college.
Author: Stephan Herzig
Publisher: Springer
ISBN: 3319298062
Category : Medical
Languages : en
Pages : 466
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Book Description
The HEP issue on Metabolic Control provides a state-of the art overview over both classical concepts and emerging areas in metabolism and associated disorders. In this context, metabolic control is highlighted at various levels of complexity ranging from transcriptional mechanisms in metabolic pathway control over metabolic communication routes in physiology and pathophysiology to current treatment modalities and options in metabolic disorders, including type 2 diabetes and obesity. Dedicated chapters by leading experts in their fields provide a concise overview over important areas in metabolic research at a molecular level, including the role of the central nervous system in metabolism, inflammation and metabolism, pancreatic hormone signaling, brown adipose tissue, and therapeutic concepts.
Author: Sang Yup Lee
Publisher: John Wiley & Sons
ISBN: 352782345X
Category : Science
Languages : en
Pages : 1075
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Book Description
Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation. Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya. The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about: Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It's comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.
Author: Naa Adamafio
Publisher: iUniverse
ISBN: 0595340679
Category : Science
Languages : en
Pages : 160
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Book Description
Fully understanding the complex process of the integration and control of metabolism in cellular organisms requires knowledge in several fundamental concepts. Drawing on nearly two decades of innovative studies, Doctors Naa Adamafio, Laud Okine, and Jonathan Adjimani specifically target the intricacies of metabolism and provide a comprehensive approach to the subject. The text is divided into three essential areas of study: Fundamentals of metabolic control--dealing with the basic concepts of metabolic control and the role played by regulatory enzymes Control of cellular metabolism--including the regulation of the metabolism of major biomolecules, such as carbohydrates, lipids, and compounds containing nitrogen The integration of metabolism--observing the methods in which various metabolic pathways within and between tissues and organs are integrated Whether you are an undergraduate student in biochemistry, a medical student in your preclinical years, or a teacher in the subject area, Integration and Control of Metabolism is a valuable medical resource.
Author: Peter W. Hochachka
Publisher: Harvard University Press
ISBN: 9780674569768
Category : Medical
Languages : en
Pages : 260
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Book Description
Freshwater turtles and goldfish can survive for several days without oxygen, some diving turtles for several months; hibernating animals can exist without food for long periods; others can survive extreme conditions such as desiccation, freezing, and thawing. These creatures are, in effect, self-sustaining life-support systems, with a mysterious ability to regulate their own metabolisms. These capabilities raise important questions, which Hochachka and Guppy explore in this seminal new book. What mechanisms turn down (or off) cell metabolism and other cell functions? How does an animal such as an opossum know when to activate mechanisms for slowing or stopping tissue and organ functions? How does it know when to turn them on again? How extensive is metabolic arrest as a defense against harsh environmental conditions? Can we decipher universal principles of metabolic arrest from available data? The lessons to be learned are of potentially great interest to clinicians, because the authors provide a theoretical framework in which to organize an attack on the all-too-practical problem of protecting tissues against hypoxia. Areas that may be influenced include research on cardiac arrest, strokes, acute renal failure, liver ischemia, lung injury, respiratory defense syndrome, claudication, shock, and organ transplant. Investigation of other metabolic arrest mechanisms may be similarly useful in both clinical and agricultural fields. This is a pioneering book of great use to biomedical/clinical researchers and to biologists, biochemists, and physiologists generally.
Author: David Fell
Publisher:
ISBN:
Category :
Languages : en
Pages : 301
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Book Description
Author: David Gibson
Publisher: CRC Press
ISBN: 1482264757
Category : Medical
Languages : en
Pages : 242
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Book Description
Metabolic Regulation in Mammals presents the basic principles of metabolic control, based on investigations conducted during the past 20 years. It explains the impact of recent advances in cell biology, molecular biology, and genetics on the field. This text covers all angles of metabolic regulation, including blood caloric homeostasis, cardiac and skeletal muscle, adipose tissue, and liver metabolism. Review questions, summary sections, and worked examples help break down the complexity of the subject, and details of metabolic pathways are provided for each body system, along with accompanying charts. This text is ideal for undergraduates in biological and health science disciplines.
Author: Henry J. Vogel
Publisher: Academic Press
ISBN: 1483265544
Category : Science
Languages : en
Pages : 597
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Book Description
Metabolic Pathways, Third Edition, Volume V: Metabolic Regulation presents the regulation of metabolism in terms of the control of protein synthesis. This book discusses the significance of the control of metabolism in regard to the remarkable mechanisms involved and to the provision of an effective conceptual framework for appreciating the workings of the cell. Organized into 15 chapters, this edition begins with an overview of the numerous and diversified activities of a living cell. This text then examines the ability of living organisms to regulate the storage and mobilization of metabolizable energy. Other chapters consider the cytochrome system that represents the final common path of oxidation and coupled phosphorylation in the eukaryotic cell. This book discusses as well the profound changes that cell metabolism undergoes during differentiation. The final chapter deals with the chemical and genetic bases of the induction response in Gram-positive bacteria. This book is a valuable resource for biologists and physicians.
