Opportunities for Organ Donor Intervention Research

Opportunities for Organ Donor Intervention Research PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309464870
Category : Medical
Languages : en
Pages : 171

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Book Description
The organ donation and transplantation system strives to honor the gift of donated organs by fully using those organs to save and improve the quality of the lives of their recipients. However, there are not enough donated organs to meet the demand and some donated organs may not be recovered, some recovered organs may not be transplanted, and some transplanted organs may not function adequately. Organ donor intervention research can test and assess interventions (e.g., medications, devices, and donor management protocols) to maintain or improve organ quality prior to, during, and following transplantation. The intervention is administered either while the organ is still in the deceased donor or after it is recovered from the donor but before it is transplanted into a recipient. Organ donor intervention research presents new challenges to the organ donation and transplantation community because of ethical questions about who should be considered a human subject in a research study, whose permission and oversight are needed, and how to ensure that such research does not threaten the equitable distribution of a scarce and valuable resource. Opportunities for Organ Donor Intervention Research focuses on the ethical, legal, regulatory, policy, and organizational issues relevant to the conduct of research in the United States involving deceased organ donors. This report provides recommendations for how to conduct organ donor intervention research in a manner that maintains high ethical standards, that ensures dignity and respect for deceased organ donors and their families, that provides transparency and information for transplant candidates who might receive a research organ, and that supports and sustains the public's trust in the process of organ donation and transplantation.

Opportunities for Organ Donor Intervention Research

Opportunities for Organ Donor Intervention Research PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309464870
Category : Medical
Languages : en
Pages : 171

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Book Description
The organ donation and transplantation system strives to honor the gift of donated organs by fully using those organs to save and improve the quality of the lives of their recipients. However, there are not enough donated organs to meet the demand and some donated organs may not be recovered, some recovered organs may not be transplanted, and some transplanted organs may not function adequately. Organ donor intervention research can test and assess interventions (e.g., medications, devices, and donor management protocols) to maintain or improve organ quality prior to, during, and following transplantation. The intervention is administered either while the organ is still in the deceased donor or after it is recovered from the donor but before it is transplanted into a recipient. Organ donor intervention research presents new challenges to the organ donation and transplantation community because of ethical questions about who should be considered a human subject in a research study, whose permission and oversight are needed, and how to ensure that such research does not threaten the equitable distribution of a scarce and valuable resource. Opportunities for Organ Donor Intervention Research focuses on the ethical, legal, regulatory, policy, and organizational issues relevant to the conduct of research in the United States involving deceased organ donors. This report provides recommendations for how to conduct organ donor intervention research in a manner that maintains high ethical standards, that ensures dignity and respect for deceased organ donors and their families, that provides transparency and information for transplant candidates who might receive a research organ, and that supports and sustains the public's trust in the process of organ donation and transplantation.

Contemporary Bioethics

Contemporary Bioethics PDF Author: Mohammed Ali Al-Bar
Publisher: Springer
ISBN: 3319184288
Category : Medical
Languages : en
Pages : 267

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Book Description
This book discusses the common principles of morality and ethics derived from divinely endowed intuitive reason through the creation of al-fitr' a (nature) and human intellect (al-‘aql). Biomedical topics are presented and ethical issues related to topics such as genetic testing, assisted reproduction and organ transplantation are discussed. Whereas these natural sources are God’s special gifts to human beings, God’s revelation as given to the prophets is the supernatural source of divine guidance through which human communities have been guided at all times through history. The second part of the book concentrates on the objectives of Islamic religious practice – the maqa' sid – which include: Preservation of Faith, Preservation of Life, Preservation of Mind (intellect and reason), Preservation of Progeny (al-nasl) and Preservation of Property. Lastly, the third part of the book discusses selected topical issues, including abortion, assisted reproduction devices, genetics, organ transplantation, brain death and end-of-life aspects. For each topic, the current medical evidence is followed by a detailed discussion of the ethical issues involved.

Organ and Tissue Donation

Organ and Tissue Donation PDF Author: Bethany Spielman
Publisher:
ISBN: 9780809321087
Category : Donation of organs, tissues, etc
Languages : en
Pages : 0

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Book Description
This volume brings together a wide range of views on the ethical, legal, and policy questions that have shaped the often-heated debate about organ and tissue donation in the 1990s. In this edited volume, Bethany Spielman includes selected papers from a 1995 conference cosponsored by the Department of Medical Humanities of the Southern Illinois University School of Medicine and the "Life Goes On" Organ/Tissue Donor Awareness Program of the Illinois Secretary of State. Seventeen distinguished experts from the fields of bioethics, medicine, law, history, philosophy, and public policy consider questions integral to the foundations and operations of organ donation in the 1990s.

Psychological and Social Aspects of Human Tissue Transplantation

Psychological and Social Aspects of Human Tissue Transplantation PDF Author: Jacquelyn H. Hall
Publisher:
ISBN:
Category : Transplantation of organs, tissues, etc
Languages : en
Pages : 52

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Book Description


Legislative Responses to Organ Transplantation

Legislative Responses to Organ Transplantation PDF Author: World Health Organization
Publisher: Martinus Nijhoff Publishers
ISBN: 9004635742
Category : Law
Languages : en
Pages : 509

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Book Description
Organ transplantation has, over a period of a few decades, evolved from a daring experimental medical procedure to a widely used health technology. Many lives have been saved, and the quality of life of many other persons has been immeasurably improved. There is now an abundant literature on the medical aspects of transplantation, and an increasing number of books on the legal and ethical aspects -- aspects with which WHO has been concerned since the World Health Assembly first took up the matter in 1986. This book is the first global collection of laws and regulations dealing with organ transplantation. Also included are the texts of some of the key international and European declarations and statements on the subject. Most of the materials that appear in the book were originally published in the WHO's International Digest of Health Legislation, but have never been collected in one volume before. This book will be useful to parliamentarians, health policy makers, surgeons and other health professionals involved in transplantation, transplant coordinators, ethicists, and others interested in in-depth information on how different governments and institutions have responded to the considerable ethical, legal and policy challenges posed by this important branch of curative medicine.

Organ and Tissue Transplantation

Organ and Tissue Transplantation PDF Author: David Price
Publisher: Routledge
ISBN: 135191345X
Category : Law
Languages : en
Pages : 605

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Book Description
Organ transplantation has been one of the miracles of modern-day medicine but, in addition to presenting enormous technical and clinical challenges, it throws up major ethical and legal issues principally from the perspective of the donor. Evolving capabilities in the spheres of both organ and tissue transplantation, coupled with rapidly-escalating demand, assert consistent and critical pressure on our ethical and legal principles and frameworks, including the expansion of the potential donor pool beyond the conventional categories of donor. This volume brings together seminal papers analyzing such matters in the context of an ever-increasingly important area of clinical practice.

Legal and Ethical Aspects of Fetal Tissue Transplantation

Legal and Ethical Aspects of Fetal Tissue Transplantation PDF Author: Arthur R. Bauer
Publisher: R G Landes Company
ISBN: 9781570590214
Category : Fetal tissues
Languages : en
Pages : 124

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Book Description
For obstetricians, gynaecologists, lawyers and government policy makers involved in issues surrounding this issue, this book discusses foetal tissue transplantation. It provides the history and methodology of the foetal transplant procedure, and explores various aspects of the procedure, including the need for foetal tissue and available alternatives. The book discusses present and proposed regulations covering such research and use; and examines such legal issues as informed consent, ownership of bodily tissue, practitioner liability.

Legal and Ethical Aspects of Organ Transplantation

Legal and Ethical Aspects of Organ Transplantation PDF Author: David Price
Publisher: Cambridge University Press
ISBN: 9780521651646
Category : Law
Languages : en
Pages : 508

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Book Description
A comprehensive analysis of existing laws and policies governing organ transplantation practices around the world.

Human Tissue in Transplantation and Research

Human Tissue in Transplantation and Research PDF Author: David Price
Publisher: Cambridge University Press
ISBN: 0521883024
Category : Law
Languages : en
Pages : 329

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Book Description
A proposal for resolving tensions between professionals and society regarding tissue for transplants and research, while properly protecting donors' interests.

Human Fetal Tissue Transplantation

Human Fetal Tissue Transplantation PDF Author: Niranjan Bhattacharya
Publisher: Springer Science & Business Media
ISBN: 1447141717
Category : Medical
Languages : en
Pages : 462

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Book Description
Many diseases earlier considered to be incurable are now being treated with modern innovations involving fetal tissue transplants and stem cells derived from fetal tissues. Fetal tissues are the richest source of fetal stem cells as well as other varying states of differentiated cells and support or stromal cells. The activity of such stem cells is at their peak provided they are given the correct niche. Stem cells, as we know, are immortal cells with the capacity to regenerate into any kind of differentiated cell as per niche-guidance. As such, fetal tissues have the potential capacity to mend, regenerate and repair damaged cells or tissues in adults, when directly transplanted to the site of injury, or even when transplanted in some other site, because it may have a homing capacity to migrate to the site of the specific injured organ. This is a new area of translational research and needs to be highlighted because of its immense potential. This book will bring together the new work of prominent medical scientists and clinicians who are conducting pioneering research in human fetal tissue transplantation. This will include direct transplant of healthy fetal tissue into mature patients as well as in hosts with genetic diseases. Transplant techniques, donor-host interaction, cell and tissue storage, ethical and legal issues, are some of the many matters which the book will deal with.