Mechanistic Studies on Aspartate Transcarbamylase Using Heavy Atom Isotope Effects PDF Download
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Author: Laura E. Parmentier
Publisher:
ISBN:
Category :
Languages : en
Pages : 554
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Author: Laura E. Parmentier
Publisher:
ISBN:
Category :
Languages : en
Pages : 554
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Author: Eric Ramon Johnson
Publisher:
ISBN:
Category :
Languages : en
Pages : 330
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Author:
Publisher:
ISBN:
Category : Dissertation abstracts
Languages : en
Pages : 768
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Author: Paul F. Cook
Publisher: CRC Press
ISBN: 9780849353123
Category : Medical
Languages : en
Pages : 656
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Book Description
Isotope effects have become one of the most powerful tools available to the enzymologist for probing enzymic mechanisms. Enzyme Mechanism from Isotope Effects presents the basic theory underlying isotope effects, including the latest findings on proton tunneling and coupled atomic notions. Specific theoretical applications are emphasized in regard to the types of information that can be obtained using isotope effects. The book also examines recent theoretical treatments of the product dependence of deuterium isotope effects, multiple isotope effects and isotope effects on intermediate partitioning. Other topics include a complete discussion of methods for measuring isotope effects, including a detailed description of the use of the isotope ratio mass spectrometer to obtain isotope effects, and a review of the literature regarding mechanistic information obtained from isotope effects for individual classes of enzyme-catalyzed reactions. Enzyme Mechanism from Isotope Effects is an excellent reference source for investigators using isotope effects in their research. The book is also valuable for reference libraries and instructors teaching courses in enzyme mechanism.
Author:
Publisher: Academic Press
ISBN: 0128122749
Category : Medical
Languages : en
Pages : 634
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Book Description
Experimental Analysis of Enzyme Mechanism Using Isotope Effects, Volume 596, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this comprehensive update include Measurement of enzyme binding isotope effects, Chemical ligation and isotope labeling to locate dynamic effects, Measurement of heavy enzyme isotope effects, Extracting kinetic isotope effects from a global analysis of reaction progress curves, KIE of metabolic flux and enzymes, Solvent and Primary KIE on Flavin Enzymes, and The Rapid Determination of Primary Deuterium Isotope Effects on Enzyme-Catalyzed Proton Transfer at Carbon in 50/50 HOH/DOD. Readers who are interested in applying or understanding this research will find useful methods currently used for measuring isotope effects on solution and enzyme reactions. Written by pioneers of modern isotope effect research Is the only collection of modern kinetic isotope effect methods currently available
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 734
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Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 920
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Author: Philip J. Snodgrass
Publisher: Springer Science & Business Media
ISBN: 1441990623
Category : Science
Languages : en
Pages : 255
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Book Description
Ornithine Transcarbamylase: Basic Science and Clinical Considerations, written by a leading expert on OTC, for the first time assembles and analyzes more than 40 years of basic science and clinical research. It will be the definitive resource on the topic for pediatricians, geneticists, and internists who care for patients with OTC deficiency, as well as for basic scientists and genetic researchers who study the urea cycle in mammals and the arginine biosynthetic pathway in bacteria and fungi.
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Category : Nuclear energy
Languages : en
Pages : 2174
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Author:
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Category : Biochemistry
Languages : en
Pages : 786
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