Mathematical and Computational Studies on Progress, Prognosis, Prevention and Panacea of Breast Cancer PDF Download
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Author: Suhrit Dey
Publisher: Springer Nature
ISBN: 9811660778
Category : Computers
Languages : en
Pages : 377
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Book Description
This book’s aim is to study the mathematical and computational models to analyze the progress, prognosis, prevention, and panacea of breast cancer. The book discusses application of Markov chains and transient mappings, Charlie–Simpson numerical algorithm, models represented by nonlinear reaction–diffusion-type partial differential equations, and related techniques. The book also attempts to design mathematical model of targeted strategic treatments by using Skilled Killer Drugs (SKD1 and SKD2) to suggest the improvisation of future cancer treatments. Both graduate students and researchers of computational biology and oncologists will benefit by studying this book. Researchers of cancer studies and biological sciences will also find this work helpful.
Author: Suhrit Dey
Publisher: Springer Nature
ISBN: 9811660778
Category : Computers
Languages : en
Pages : 377
Get Book Here
Book Description
This book’s aim is to study the mathematical and computational models to analyze the progress, prognosis, prevention, and panacea of breast cancer. The book discusses application of Markov chains and transient mappings, Charlie–Simpson numerical algorithm, models represented by nonlinear reaction–diffusion-type partial differential equations, and related techniques. The book also attempts to design mathematical model of targeted strategic treatments by using Skilled Killer Drugs (SKD1 and SKD2) to suggest the improvisation of future cancer treatments. Both graduate students and researchers of computational biology and oncologists will benefit by studying this book. Researchers of cancer studies and biological sciences will also find this work helpful.
Author: Suhrit Dey
Publisher: CRC Press
ISBN: 1040014933
Category : Mathematics
Languages : en
Pages : 327
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Book Description
Perturbed functional iterations (PFI) is a large‐scale nonlinear system solver. Nature is abundant with events simulated mathematically by nonlinear systems of equations and inequalities. These we call nonlinear models. Often, they are ill‐conditioned, meaning small changes in data causing huge changes in the output. PFI, previously called the perturbed iterative scheme (PIS), is a numerical method to solve nonlinear systems of equations in multidimensional space. Computational results demonstrate that this numerical method has some unique features, which have made it more practical for applications in engineering and applied mathematics. This book will guide readers in the proper use of PFI, both in theoretical and practical settings. Features: Ideal resource for postgraduates and professional researchers in science and engineering working in nonlinear systems Algorithmically simple enough for engineers and applied scientists to write their own software based on the contents
Author: Eric J. Bieber
Publisher: Cambridge University Press
ISBN: 1107040396
Category : Medical
Languages : en
Pages : 1127
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Book Description
Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.
Author: World Health Organization Staff
Publisher:
ISBN: 9789241561990
Category : Medical
Languages : en
Pages : 270
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Book Description
This book provides a practical guide to the design and implementation of health information systems in developing countries. Noting that most existing systems fail to deliver timely, reliable, and relevant information, the book responds to the urgent need to restructure systems and make them work as both a resource for routine decisions and a powerful tool for improving health services. With this need in mind, the authors draw on their extensive personal experiences to map out strategies, pinpoint common pitfalls, and guide readers through a host of conceptual and technical options. Information needs at all levels - from patient care to management of the national health system - are considered in this comprehensive guide. Recommended lines of action are specific to conditions seen in government-managed health systems in the developing world. In view of common constraints on time and resources, the book concentrates on strategies that do not require large resources, highly trained staff, or complex equipment. Throughout the book, case studies and numerous practical examples are used to explore problems and illustrate solutions. Details range from a list of weaknesses that plague most existing systems, through advice on when to introduce computers and how to choose appropriate software and hardware, to the hotly debated question of whether patient records should be kept by the patient or filed at the health unit. The book has fourteen chapters presented in four parts. Chapters in the first part, on information for decision-making, explain the potential role of health information as a managerial tool, consider the reasons why this potential is rarely realized, and propose general approaches for reform which have proved successful in several developing countries. Presentation of a six-step procedure for restructuring information systems, closely linked to an organizational model of health services, is followed by a practical discussion of the decision-making process. Reasons for the failure of most health information to influence decisions are also critically assessed. Against this background, the second and most extensive part provides a step-by-step guide to the restructuring of information systems aimed at improving the quality and relevance of data and ensuring their better use in planning and management. Steps covered include the identification of information needs and indicators, assessment of the existing system, and the collection of both routine and non-routine data using recommended procedures and instruments. Chapters also offer advice on procedures for data transmission and processing, and discuss the requirements of systems designed to collect population-based community information. Resource needs and technical tools are addressed in part three. A comprehensive overview of the resource base - from staff and training to the purchase and maintenance of equipment - is followed by chapters offering advice on the introduction of computerized systems in developing countries, and explaining the many applications of geographic information systems. Practical advice on how to restructure a health information system is provided in the final part, which considers how different interest groups can influence the design and implementation of a new system, and proposes various design options for overcoming specific problems. Experiences from several developing countries are used to illustrate strategies and designs in terms of those almost certain to fail and those that have the greatest chances of success
Author: Mani Mehra
Publisher: Springer
ISBN: 9811325952
Category : Mathematics
Languages : en
Pages : 185
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Book Description
This book provides comprehensive information on the conceptual basis of wavelet theory and it applications. Maintaining an essential balance between mathematical rigour and the practical applications of wavelet theory, the book is closely linked to the wavelet MATLAB toolbox, which is accompanied, wherever applicable, by relevant MATLAB codes. The book is divided into four parts, the first of which is devoted to the mathematical foundations. The second part offers a basic introduction to wavelets. The third part discusses wavelet-based numerical methods for differential equations, while the last part highlights applications of wavelets in other fields. The book is ideally suited as a text for undergraduate and graduate students of mathematics and engineering.
Author: Thomas S. Deisboeck
Publisher: CRC Press
ISBN: 1439814422
Category : Mathematics
Languages : en
Pages : 492
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Book Description
Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat
Author: Mandy Ryan
Publisher: Springer Science & Business Media
ISBN: 1402057539
Category : Business & Economics
Languages : en
Pages : 265
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Book Description
This work takes a fresh and contemporary look at the growing interest in the development and application of discrete choice experiments (DCEs) within the field of health economics. The book comprises chapters by highly regarded academics with experience of applying DCEs in the area of health. Thus the book is relevant to post-graduate students and applied researchers with an interest in the use of DCEs for valuing health and health care and has international appeal.
Author: Mark Petticrew
Publisher: John Wiley & Sons
ISBN: 1405150149
Category : Psychology
Languages : en
Pages : 352
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Book Description
Such diverse thinkers as Lao-Tze, Confucius, and U.S. Defense Secretary Donald Rumsfeld have all pointed out that we need to be able to tell the difference between real and assumed knowledge. The systematic review is a scientific tool that can help with this difficult task. It can help, for example, with appraising, summarising, and communicating the results and implications of otherwise unmanageable quantities of data. This book, written by two highly-respected social scientists, provides an overview of systematic literature review methods: Outlining the rationale and methods of systematic reviews; Giving worked examples from social science and other fields; Applying the practice to all social science disciplines; It requires no previous knowledge, but takes the reader through the process stage by stage; Drawing on examples from such diverse fields as psychology, criminology, education, transport, social welfare, public health, and housing and urban policy, among others. Including detailed sections on assessing the quality of both quantitative, and qualitative research; searching for evidence in the social sciences; meta-analytic and other methods of evidence synthesis; publication bias; heterogeneity; and approaches to dissemination.
Author: Sofia Dias
Publisher: John Wiley & Sons
ISBN: 1118647505
Category : Mathematics
Languages : en
Pages : 484
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Book Description
A practical guide to network meta-analysis with examples and code In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish which interventions are effective and cost-effective. Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision making when there are two or more treatment alternatives being evaluated, and assumes that the purpose of every synthesis is to answer the question "for this pre-identified population of patients, which treatment is 'best'?" A comprehensive, coherent framework for network meta-analysis (mixed treatment comparisons) is adopted and estimated using Bayesian Markov Chain Monte Carlo methods implemented in the freely available software WinBUGS. Each chapter contains worked examples, exercises, solutions and code that may be adapted by readers to apply to their own analyses. This book can be used as an introduction to evidence synthesis and network meta-analysis, its key properties and policy implications. Examples and advanced methods are also presented for the more experienced reader. Methods used throughout this book can be applied consistently: model critique and checking for evidence consistency are emphasised. Methods are based on technical support documents produced for NICE Decision Support Unit, which support the NICE Methods of Technology Appraisal. Code presented is also the basis for the code used by the ISPOR Task Force on Indirect Comparisons. Includes extensive carefully worked examples, with thorough explanations of how to set out data for use in WinBUGS and how to interpret the output. Network Meta-Analysis for Decision Making will be of interest to decision makers, medical statisticians, health economists, and anyone involved in Health Technology Assessment including the pharmaceutical industry.
Author: P.V. Subrahmanyam
Publisher: Springer
ISBN: 9811331588
Category : Mathematics
Languages : en
Pages : 306
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Book Description
This book provides a primary resource in basic fixed-point theorems due to Banach, Brouwer, Schauder and Tarski and their applications. Key topics covered include Sharkovsky’s theorem on periodic points, Thron’s results on the convergence of certain real iterates, Shield’s common fixed theorem for a commuting family of analytic functions and Bergweiler’s existence theorem on fixed points of the composition of certain meromorphic functions with transcendental entire functions. Generalizations of Tarski’s theorem by Merrifield and Stein and Abian’s proof of the equivalence of Bourbaki–Zermelo fixed-point theorem and the Axiom of Choice are described in the setting of posets. A detailed treatment of Ward’s theory of partially ordered topological spaces culminates in Sherrer fixed-point theorem. It elaborates Manka’s proof of the fixed-point property of arcwise connected hereditarily unicoherent continua, based on the connection he observed between set theory and fixed-point theory via a certain partial order. Contraction principle is provided with two proofs: one due to Palais and the other due to Barranga. Applications of the contraction principle include the proofs of algebraic Weierstrass preparation theorem, a Cauchy–Kowalevsky theorem for partial differential equations and the central limit theorem. It also provides a proof of the converse of the contraction principle due to Jachymski, a proof of fixed point theorem for continuous generalized contractions, a proof of Browder–Gohde–Kirk fixed point theorem, a proof of Stalling's generalization of Brouwer's theorem, examine Caristi's fixed point theorem, and highlights Kakutani's theorems on common fixed points and their applications.
