Maternal Control of Development in Vertebrates

Maternal Control of Development in Vertebrates PDF Author: Florence Louise Marlow
Publisher: Morgan & Claypool Publishers
ISBN: 161504051X
Category : Family & Relationships
Languages : en
Pages : 221

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Book Description
Eggs of all animals contain mRNAs and proteins that are supplied to or deposited in the egg as it develops during oogenesis. These maternal gene products regulate all aspects of oocyte development, and an embryo fully relies on these maternal gene products for all aspects of its early development, including fertilization, transitions between meiotic and mitotic cell cycles, and activation of its own genome. Given the diverse processes required to produce a developmentally competent egg and embryo, it is not surprising that maternal gene products are not only essential for normal embryonic development but also for fertility. This review provides an overview of fundamental aspects of oocyte and early embryonic development and the interference and genetic approaches that have provided access to maternally regulated aspects of vertebrate development. Some of the pathways and molecules highlighted in this review, in particular, Bmps, Wnts, small GTPases, cytoskeletal components, and cell cycle regulators, are well known and are essential regulators of multiple aspects of animal development, including oogenesis, early embryogenesis, organogenesis, and reproductive fitness of the adult animal. Specific examples of developmental processes under maternal control and the essential proteins will be explored in each chapter, and where known conserved aspects or divergent roles for these maternal regulators of early vertebrate development will be discussed throughout this review. Table of Contents: Introduction / Oogenesis: From Germline Stem Cells to Germline Cysts / Oocyte Polarity and the Embryonic Axes: The Balbiani Body, an Ancient Oocyte Asymmetry / Preparing Developmentally Competent Eggs / Egg Activation / Blocking Polyspermy / Cleavage/ Mitosis: Going Multicellular / Maternal-Zygotic Transition / Reprogramming: Epigenetic Modifications and Zygotic Genome Activation / Dorsal-Ventral Axis Formation before Zygotic Genome Activation in Zebrafish and Frogs / Maternal TGF-β and the Dorsal-Ventral Embryonic Axis / Maternal Control After Zygotic Genome Activation / Compensation by Stable Maternal Proteins / Maternal Contributions to Germline Establishment or Maintenance / Perspective / Acknowledgments / References

Maternal Control of Development in Vertebrates

Maternal Control of Development in Vertebrates PDF Author: Florence Louise Marlow
Publisher: Morgan & Claypool Publishers
ISBN: 161504051X
Category : Family & Relationships
Languages : en
Pages : 221

Get Book

Book Description
Eggs of all animals contain mRNAs and proteins that are supplied to or deposited in the egg as it develops during oogenesis. These maternal gene products regulate all aspects of oocyte development, and an embryo fully relies on these maternal gene products for all aspects of its early development, including fertilization, transitions between meiotic and mitotic cell cycles, and activation of its own genome. Given the diverse processes required to produce a developmentally competent egg and embryo, it is not surprising that maternal gene products are not only essential for normal embryonic development but also for fertility. This review provides an overview of fundamental aspects of oocyte and early embryonic development and the interference and genetic approaches that have provided access to maternally regulated aspects of vertebrate development. Some of the pathways and molecules highlighted in this review, in particular, Bmps, Wnts, small GTPases, cytoskeletal components, and cell cycle regulators, are well known and are essential regulators of multiple aspects of animal development, including oogenesis, early embryogenesis, organogenesis, and reproductive fitness of the adult animal. Specific examples of developmental processes under maternal control and the essential proteins will be explored in each chapter, and where known conserved aspects or divergent roles for these maternal regulators of early vertebrate development will be discussed throughout this review. Table of Contents: Introduction / Oogenesis: From Germline Stem Cells to Germline Cysts / Oocyte Polarity and the Embryonic Axes: The Balbiani Body, an Ancient Oocyte Asymmetry / Preparing Developmentally Competent Eggs / Egg Activation / Blocking Polyspermy / Cleavage/ Mitosis: Going Multicellular / Maternal-Zygotic Transition / Reprogramming: Epigenetic Modifications and Zygotic Genome Activation / Dorsal-Ventral Axis Formation before Zygotic Genome Activation in Zebrafish and Frogs / Maternal TGF-β and the Dorsal-Ventral Embryonic Axis / Maternal Control After Zygotic Genome Activation / Compensation by Stable Maternal Proteins / Maternal Contributions to Germline Establishment or Maintenance / Perspective / Acknowledgments / References

The Birth Of A Mother

The Birth Of A Mother PDF Author: Daniel N Stern
Publisher: Basic Books
ISBN: 0786724625
Category : Psychology
Languages : en
Pages : 256

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Book Description
As you prepare to become a mother, you face an experience unlike any other in your life. Having a baby will redirect your preferences and pleasures and, most likely, will realign some of your values.As you undergo this unique psychological transformation, you will be guided by new hopes, fears, and priorities. In a most startling way, having a child will influence all of your closest relationships and redefine your role in your family's history. The charting of this remarkable, new realm is the subject of this compelling book.Renowned psychiatrist Daniel N. Stern has joined forces with pediatrician and child psychiatrist Nadia Bruschweiler-Stern and journalist Alison Freeland to paint a wonderfully evocative picture of the psychology of motherhood. At the heart of The Birth of a Mother is an arresting premise: Just as a baby develops physically in utero and after birth, so a mother is born psychologically in the many months that precede and follow the birth of her baby.The recognition of this inner transformation emerges from hundreds of interviews with new mothers and decades of clinical experience. Filled with revealing case studies and personal comments from women who have shared this experience, this book will serve as an invaluable sourcebook for new mothers, validating the often confusing emotions that accompany the development of this new identity. In addition to providing insight into the unique state of motherhood, the authors touch on related topics such as going back to work, fatherhood, adoption, and premature birth.During pregnancy, mothers-to-be talk about morning sickness and their changing bodies, and new mothers talk about their exhaustion, the benefits of nursing or bottle-feeding, and the dilemma of whether or when they should return to work. And yet, they can be strangely mute about the dramatic and often overwhelming changes going on in their inner lives. Finally, with The Birth of a Mother, these powerful feelings are eloquently put into words.

Maternal Transition

Maternal Transition PDF Author: Candace Johnson
Publisher: Routledge
ISBN: 1317704606
Category : Political Science
Languages : en
Pages : 243

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Book Description
What are the political dimensions that are revealed in women’s preferences for health care during pregnancy and childbirth? The answers to this question vary from one community to the next, and often from woman to the next, although the trends in the Global North and South are strikingly different. Employing three conceptual frames; medicalization, the public-private distinction, and intersectionality, Candace Johnson examines these differences through the narratives of women in Canada, the United States, Cuba, and Honduras. In Canada and the United States, women from privileged and marginalized social groups demonstrate the differences across the North-South divide, and women in Cuba and Honduras speak to the realities of severely constrained decision-making in developing countries. Each case study includes narratives drawn from in-depth interviews with women who were pregnant or who had recently had children. Johnson argues that women’s expressed preferences in different contexts reveal important details about the inequality that they experience in that context, in addition to as various elements of identity. Both inequality and identity are affected by the ways in which women experience the division between public and private lives – the life of the community and the life of the home and family – as well as the consequences of intersectionality – the combinations of various sources of disadvantage and women’s reactions to these, either in the form of resistance or compliance. The rigorous and highly original cross cultural and comparative research on health, gender, poverty and social context makes Maternal Transition an excellent contribution to global maternal health policy debates.

Growing Up Global

Growing Up Global PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030909528X
Category : Social Science
Languages : en
Pages : 721

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Book Description
The challenges for young people making the transition to adulthood are greater today than ever before. Globalization, with its power to reach across national boundaries and into the smallest communities, carries with it the transformative power of new markets and new technology. At the same time, globalization brings with it new ideas and lifestyles that can conflict with traditional norms and values. And while the economic benefits are potentially enormous, the actual course of globalization has not been without its critics who charge that, to date, the gains have been very unevenly distributed, generating a new set of problems associated with rising inequality and social polarization. Regardless of how the globalization debate is resolved, it is clear that as broad global forces transform the world in which the next generation will live and work, the choices that today's young people make or others make on their behalf will facilitate or constrain their success as adults. Traditional expectations regarding future employment prospects and life experiences are no longer valid. Growing Up Global examines how the transition to adulthood is changing in developing countries, and what the implications of these changes might be for those responsible for designing youth policies and programs, in particular, those affecting adolescent reproductive health. The report sets forth a framework that identifies criteria for successful transitions in the context of contemporary global changes for five key adult roles: adult worker, citizen and community participant, spouse, parent, and household manager.

Transition to Parenthood

Transition to Parenthood PDF Author: Roudi Nazarinia Roy
Publisher: Springer Science & Business Media
ISBN: 1461477689
Category : Social Science
Languages : en
Pages : 223

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Book Description
Transition to Parenthood moves beyond a one-study focus and captures multidisciplinary work on all families making the transition to parenthood. The book covers societal trends, changes, and most importantly expectations. Focus is also placed on how families are impacted by their surroundings and their individual members. Strengths and limitations of current theories are discussed, as well as how the phenomenon of parenthood requires a combination of both macro- and micro-level theories.

Found in Transition

Found in Transition PDF Author: Paria Hassouri
Publisher: New World Library
ISBN: 1608687082
Category : Biography & Autobiography
Languages : en
Pages : 236

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Book Description
On Thanksgiving morning, Paria Hassouri finds herself furiously praying and negotiating with the universe as she irons a dress her fourteen-year-old, designated male at birth, has secretly purchased and wants to wear to dinner with the extended family. In this wonderfully frank, loving, and practical account of parenting a transgender teen, Paria chronicles what amounts to a dual transition: as her child transitions from male to female, she navigates through anger, denial, and grief to eventually arrive at acceptance. Despite her experience advising other parents in her work as a pediatrician, she was blindsided by her child's gender identity. Paria is also forced to examine how she still carries insecurities from her past of growing up as an Iranian-American immigrant in a predominantly white neighborhood, and how her life experience is causing her to parent with fear instead of love. Paria discovers her capacity to evolve, as well as what it really means to parent and the deepest nature of unconditional love. This page-turning memoir relates a tender story of loving and parenting a teenager coming out as transgender and transitioning. It explores identity, self-discovery in adolescence and midlife, and difference in a world that values conformity. At its heart, Found in Transition is a universally inspiring portrait of what it means to be a family.

The Natural Mother of the Child

The Natural Mother of the Child PDF Author: Krys Malcolm Belc
Publisher: Catapult
ISBN: 1640094385
Category : Family & Relationships
Languages : en
Pages : 305

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Book Description
Krys Malcolm Belc's visual memoir-in-essays explores how the experience of gestational parenthood—conceiving, birthing, and breastfeeding his son Samson—eventually clarified his gender identity. Krys Malcolm Belc has thought a lot about the interplay between parenthood and gender. As a nonbinary, transmasculine parent, giving birth to his son Samson clarified his gender identity. And yet, when his partner, Anna, adopted Samson, the legal documents listed Belc as “the natural mother of the child.” By considering how the experiences contained under the umbrella of “motherhood” don’t fully align with Belc’s own experience, The Natural Mother of the Child journeys both toward and through common perceptions of what it means to have a body and how that body can influence the perception of a family. With this visual memoir in essays, Belc has created a new kind of life record, one that engages directly with the documentation often thought to constitute a record of one’s life—childhood photos, birth certificates—and addresses his deep ambivalence about the “before” and “after” so prevalent in trans stories, which feels apart from his own experience. The Natural Mother of the Child is the story of a person moving past societal expectations to take control of his own narrative, with prose that delights in the intimate dailiness of family life and explores how much we can ever really know when we enter into parenting.

Birth Settings in America

Birth Settings in America PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309669820
Category : Social Science
Languages : en
Pages : 369

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Book Description
The delivery of high quality and equitable care for both mothers and newborns is complex and requires efforts across many sectors. The United States spends more on childbirth than any other country in the world, yet outcomes are worse than other high-resource countries, and even worse for Black and Native American women. There are a variety of factors that influence childbirth, including social determinants such as income, educational levels, access to care, financing, transportation, structural racism and geographic variability in birth settings. It is important to reevaluate the United States' approach to maternal and newborn care through the lens of these factors across multiple disciplines. Birth Settings in America: Outcomes, Quality, Access, and Choice reviews and evaluates maternal and newborn care in the United States, the epidemiology of social and clinical risks in pregnancy and childbirth, birth settings research, and access to and choice of birth settings.

Becoming a Mother

Becoming a Mother PDF Author: Ramona Thieme Mercer
Publisher:
ISBN:
Category : Family & Relationships
Languages : en
Pages : 418

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Book Description
"This volume offers a comprehensive review of all the current knowledge on maternal role attainment since Reva Rubin's seminal work. Drawing from research in nursing, maternal-child health, psychology, sociology, and social work, the book examines the psychological transition to motherhood from a contemporary, multidisciplinary perspective." "Special circumstances such as preterm birth and single parenthood are discussed, as well as the effects of maternal employment and maternal age (such as teens and older mothers). This volume should be of value for use in courses in maternity nursing, women's studies, community and social psychology, and social work, as well as for health professionals providing care for the woman during pregnancy and early motherhood."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved

Disease Control Priorities, Third Edition (Volume 2)

Disease Control Priorities, Third Edition (Volume 2) PDF Author: Robert Black
Publisher: World Bank Publications
ISBN: 1464803684
Category : Medical
Languages : en
Pages : 416

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Book Description
The evaluation of reproductive, maternal, newborn, and child health (RMNCH) by the Disease Control Priorities, Third Edition (DCP3) focuses on maternal conditions, childhood illness, and malnutrition. Specifically, the chapters address acute illness and undernutrition in children, principally under age 5. It also covers maternal mortality, morbidity, stillbirth, and influences to pregnancy and pre-pregnancy. Volume 3 focuses on developments since the publication of DCP2 and will also include the transition to older childhood, in particular, the overlap and commonality with the child development volume. The DCP3 evaluation of these conditions produced three key findings: 1. There is significant difficulty in measuring the burden of key conditions such as unintended pregnancy, unsafe abortion, nonsexually transmitted infections, infertility, and violence against women. 2. Investments in the continuum of care can have significant returns for improved and equitable access, health, poverty, and health systems. 3. There is a large difference in how RMNCH conditions affect different income groups; investments in RMNCH can lessen the disparity in terms of both health and financial risk.