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Author: Jennie C. Hunter-Cevera
Publisher: Elsevier
ISBN: 0080535755
Category : Science
Languages : en
Pages : 279
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Book Description
To retain their usefulness, cultures that manufacture economically valuable products must be uncontaminated, viable, and genetically stable. Maintaining Cultures for Biotechnology and Industry gives practical advice necessary to preserve and maintain cells and microorganisms important to the biotechnology and pharmaceutical industries in ways that ensure they will continue to be able to synthesize those valuable metabolites. This book covers not just those strains currently being used but also those yet to be discovered and engineered.This text is essential for anyone working with cultures who wants to avoid the frustration of losing strains and needs to be able to devise and evaluate new strategies for preservation. - Written by hands-on experts in their respective fields - Contains helpful tables and protocols for preserving or maintaining cells, cultures and viruses - Discusses means to preserve cells by freezing, lyophilization, drying, cyoprotection, spore storage, continuous propagation and subculturing when absolutely necessary, and others - Gives information needed to test cultures for stable retention of important characteristics - Gives principles needed to devise and evaluate preservation strategies for newly identified and newly engineered cells and organisms - Lists culture sources for each class of organism - Includes information for characterizing and monitoring recombinant organisms, especially important because of their propensity for genetic stability - Discusses the history of the continually evolving field of culture preservation - Examines the importance of genetically stable cultures as it relates to maintaining patent positions
Author: Jennie C. Hunter-Cevera
Publisher: Elsevier
ISBN: 0080535755
Category : Science
Languages : en
Pages : 279
Get Book Here
Book Description
To retain their usefulness, cultures that manufacture economically valuable products must be uncontaminated, viable, and genetically stable. Maintaining Cultures for Biotechnology and Industry gives practical advice necessary to preserve and maintain cells and microorganisms important to the biotechnology and pharmaceutical industries in ways that ensure they will continue to be able to synthesize those valuable metabolites. This book covers not just those strains currently being used but also those yet to be discovered and engineered.This text is essential for anyone working with cultures who wants to avoid the frustration of losing strains and needs to be able to devise and evaluate new strategies for preservation. - Written by hands-on experts in their respective fields - Contains helpful tables and protocols for preserving or maintaining cells, cultures and viruses - Discusses means to preserve cells by freezing, lyophilization, drying, cyoprotection, spore storage, continuous propagation and subculturing when absolutely necessary, and others - Gives information needed to test cultures for stable retention of important characteristics - Gives principles needed to devise and evaluate preservation strategies for newly identified and newly engineered cells and organisms - Lists culture sources for each class of organism - Includes information for characterizing and monitoring recombinant organisms, especially important because of their propensity for genetic stability - Discusses the history of the continually evolving field of culture preservation - Examines the importance of genetically stable cultures as it relates to maintaining patent positions
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309055822
Category : Science
Languages : en
Pages : 105
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Book Description
The United States is entering an era when, more than ever, the sharing of resources and information might be critical to scientific progress. Every dollar saved by avoiding duplication of efforts and by producing economies of scale will become increasingly important as federal funding enters an era of fiscal restraint. This book focuses on six diverse case studies that share materials or equipment with the scientific community at large: the American Type Culture Collection, the multinational coordinated Arabidopsis thaliana Genome Research Project, the Jackson Laboratory, the Washington Regional Primate Research Center, the Macromolecular Crystallography Resource at the Cornell High-Energy Synchrotron Source, and the Human Genome Center at Lawrence Livermore National Laboratory. The book also identifies common strengths and problems faced in the six cases, and presents a series of recommendations aimed at facilitating resource sharing in biomedical research.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309131863
Category : Technology & Engineering
Languages : en
Pages : 476
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Book Description
This anchor volume to the series Managing Global Genetic Resources examines the structure that underlies efforts to preserve genetic material, including the worldwide network of genetic collections; the role of biotechnology; and a host of issues that surround management and use. Among the topics explored are in situ versus ex situ conservation, management of very large collections of genetic material, problems of quarantine, the controversy over ownership or copyright of genetic material, and more.
Author: Alexandru Mihai Grumezescu
Publisher: Academic Press
ISBN: 0128114959
Category : Technology & Engineering
Languages : en
Pages : 510
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Book Description
Advances in Biotechnology for Food Industry, Volume Fourteen in the Handbook of Food Bioengineering series, provides recent insight into how biotechnology impacts the global food industry and describes how food needs are diverse, requiring the development of innovative biotechnological processes to ensure efficient food production worldwide. Many approaches were developed over the last 10 years to allow faster, easier production of widely used foods, food components and therapeutic food ingredients. This volume shows how biotechnological processes increase production and quality of food products, including the development of anti-biofilm materials to decrease microbial colonization in bioreactors and food processing facilities. - Presents basic to advanced technological applications in food biotechnology - Includes various scientific techniques used to produce specific desired traits in plants, animals and microorganisms - Provides scientific advances in food processing and their impact on the environment, human health and food safety - Discusses the development of controlled co-cultivations for reproducible results in fermentation processes in food biotechnology
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309046858
Category : Medical
Languages : en
Pages : 208
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Book Description
In developing countries, traditional fermentation serves many purposes. It can improve the taste of an otherwise bland food, enhance the digestibility of a food that is difficult to assimilate, preserve food from degradation by noxious organisms, and increase nutritional value through the synthesis of essential amino acids and vitamins. Although "fermented food" has a vaguely distasteful ring, bread, wine, cheese, and yogurt are all familiar fermented foods. Less familiar are gari, ogi, idli, ugba, and other relatively unstudied but important foods in some African and Asian countries. This book reports on current research to improve the safety and nutrition of these foods through an elucidation of the microorganisms and mechanisms involved in their production. Also included are recommendations for needed research.
Author: Manju Nehra
Publisher: CRC Press
ISBN: 1000911586
Category : Technology & Engineering
Languages : en
Pages : 262
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Book Description
This new reference volume, Handbook of Industrial Food Microbiology, introduces industrial microbiology in the food industry. The techniques and technologies discussed in the book focus on production, processing, and recovery of food industry metabolites (primary or secondary). The process of alcohol production, fermentation metabolites, and drug delivery components through food are the main highlights of the book. The authors use their research and academic experience in food science and technology research and other areas of applied microbiology to serve as a foundation for this volume. The volume first provides an introduction to and history of industrial food microbiology and goes on to discuss the biology of industrial food microbiology, food fermentation systems, microbial production of metabolites, and downstream processing. The book lays out the principles of overproduction of metabolites in the food industry and also addresses biomass production, immobilization of enzymes in food systems, and waste treatment in the food industries. The volume clearly covers the elements and basic concepts of biology and microbiology for the benefit of students who may not be familiar with the biological sciences that act as base of industrial microbiology, such as, for example, graduates of chemical and civil engineering. Intended for undergraduates and beginning graduate students in chemical engineering, microbiology, and biotechnology, the volume will also be of interest to those who are studying pharmacy, biochemistry, and general biology. Students and professionals in the fields of civil engineering and public health will be interested in the section on waste disposal.
Author: Yunbi Xu
Publisher: CABI
ISBN: 1845933923
Category : Science
Languages : en
Pages : 754
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Book Description
Recent advances in plant genomics and molecular biology have revolutionized our understanding of plant genetics, providing new opportunities for more efficient and controllable plant breeding. Successful techniques require a solid understanding of the underlying molecular biology as well as experience in applied plant breeding. Bridging the gap between developments in biotechnology and its applications in plant improvement, Molecular Plant Breeding provides an integrative overview of issues from basic theories to their applications to crop improvement including molecular marker technology, gene mapping, genetic transformation, quantitative genetics, and breeding methodology.
Author: Vladimir N. Kestelman
Publisher: Springer Science & Business Media
ISBN: 1461544556
Category : Technology & Engineering
Languages : en
Pages : 286
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Book Description
Recently a new sphere in materials science· has formed which subject is structure and properties of electret materials used in engineering, medicine, biotechnology and other branches. It is characterized by specific methods of experimental investigations based on recording charge transfer, polarization and depolarization of dielectrics and involves original techniques and physico-mathematical aids where notions that exist at the interface of several natural and technical sciences are concentrated. It embraces a vast area of applications mainly in engineering, instrument making, electronics, medical technique, biotechnology, and etc., has a specialized technological base for electric polarization of dielectrics composed of uncommon technological methods, equipment and instrumentation. Apparently, future fundamental investigations in the domain of electret materials science are to be developed at the interface of computer of dielectrics. Elaboration of a simulation, physics and physical chemistry model for electric polarization of solid media with uneven charge density distribution, complicated by surface phenomena, outer electromagnetic, heat, chemical and other effects, presents a grave methodological problem. The simulation of structures in which polarization follows diffusion mechanism of chemically active molecules or their fragments, and the development of calculation methods for polarized charge relaxation and regularities of dielectric nonlinear properties, are the most urgent objectives of current research. Success in bioelectret effect studies is anticipated to result in profound widening of natural science knowledge.
Author: Roland Ulber
Publisher: Springer
ISBN: 3540456961
Category : Science
Languages : en
Pages : 309
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Book Description
With contributions by numerous experts
Author: Brian McNeil
Publisher: John Wiley & Sons
ISBN: 0470725281
Category : Science
Languages : en
Pages : 402
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Book Description
A hands-on book which begins by setting the context;- defining 'fermentation' and the possible uses of fermenters, and setting the scope for the book. It then proceeds in a methodical manner to cover the equipment for research scale fermentation labs, the different types of fermenters available, their uses and modes of operation. Once the lab is equipped, the issues of fermentation media, preservation strains and strain improvement strategies are documented, along with the use of mathematical modelling as a method for prediction and control. Broader questions such as scale-up and scale down, process monitoring and data logging and acquisition are discussed before separate chapters on animal cell culture systems and plant cell culture systems. The final chapter documents the way forward for fermenters and how they can be used for non-manufacturing purposes. A glossary of terms at the back of the book (along with a subject index) will prove invaluable for quick reference.Edited by academic consultants who have years of experience in fermentation technology, each chapter is authored by experts from both industry and academia. Industry authors come from GSK (UK), DSM (Netherlands), Eli Lilly (USA) and Broadley James (UK-USA).
