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Author: Allan Siegel
Publisher: Springer Science & Business Media
ISBN: 0387848517
Category : Medical
Languages : en
Pages : 437
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Book Description
For many years, the immune and central nervous systems were thought to function independently with little or no interaction between the two. This view has und- gone dramatic changes over the past three decades. Indeed, we now know that there exists various feedback loops between the brain and immune systems that impact signi cantly upon different behavioral processes, including normal behavior and mental disorders. Pioneering efforts in generating this change were initiated by a number of early investigators. Included were those whose efforts were directed at establishing neuroimmune connections as well as others whose research focused upon the relationship between immunity, cytokines, and behavior. This book brings together outstanding scientists and clinicians who have made major contributions to the rapidly developing eld investigating the relationship between immunity and behavior. The book is divided into three parts. The rst part describes pathways by which the brain and immune systems communicate and int- act with each other. In the chapter “Cytokines and the Blood–Brain Barrier” p- vides insight into interactions between the blood–brain barrier and cytokines. Such interactions underlie basic communication between the immune system and brain that are present in normal as well as in disease conditions. In the chapter “Neu- chemical and Endocrine Responses to Immune Activation: The Role of Cytokines,” the neurochemical and endocrine consequences of immune challenge and cytokine administration on central neurotransmitter activity are discussed.
Author: Allan Siegel
Publisher: Springer Science & Business Media
ISBN: 0387848517
Category : Medical
Languages : en
Pages : 437
Get Book Here
Book Description
For many years, the immune and central nervous systems were thought to function independently with little or no interaction between the two. This view has und- gone dramatic changes over the past three decades. Indeed, we now know that there exists various feedback loops between the brain and immune systems that impact signi cantly upon different behavioral processes, including normal behavior and mental disorders. Pioneering efforts in generating this change were initiated by a number of early investigators. Included were those whose efforts were directed at establishing neuroimmune connections as well as others whose research focused upon the relationship between immunity, cytokines, and behavior. This book brings together outstanding scientists and clinicians who have made major contributions to the rapidly developing eld investigating the relationship between immunity and behavior. The book is divided into three parts. The rst part describes pathways by which the brain and immune systems communicate and int- act with each other. In the chapter “Cytokines and the Blood–Brain Barrier” p- vides insight into interactions between the blood–brain barrier and cytokines. Such interactions underlie basic communication between the immune system and brain that are present in normal as well as in disease conditions. In the chapter “Neu- chemical and Endocrine Responses to Immune Activation: The Role of Cytokines,” the neurochemical and endocrine consequences of immune challenge and cytokine administration on central neurotransmitter activity are discussed.
Author: Christopher C. Berndt
Publisher: ASM International
ISBN: 1615032304
Category : Technology & Engineering
Languages : en
Pages : 1338
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Book Description
Author:
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 720
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Book Description
Author: Edward M. Stricker
Publisher: Springer Science & Business Media
ISBN: 0306484846
Category : Medical
Languages : en
Pages : 588
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Book Description
Like previous handbooks, the present volume is an authoritative and up-to-date compendium of information and perspective on the neurobiology of ingestive behaviors. It is intended to be stimulating and informative to the practitioner, whether neophyte or senior scholar. It is also intended to be accessible to others who do not investigate the biological bases of food and ?uid ingestion, who may teach aspects of this material or simply wonder about the current state of the ?eld. To all readers, we present this handbook as a progress report, recognizing that the present state of the ?eld is much farther along than it was the last time a handbook was published, but mindful of the likelihood that it is not as far along as it will be when the next handbook is prepared. This ?eld has witnessed a spectacular accretion of scienti?c information since the ?rst handbook was published in 1967. During the generation of science between then and the publication of the second handbook in 1990, numerous scienti?c reports have substantially changed the perspective and informational base of the ?eld.
Author: Jack P. Antel
Publisher:
ISBN: 0198510683
Category : Medical
Languages : en
Pages : 467
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Book Description
Clinical Neurimmunology is the major reference text in the field, providing broad and comprehensive coverage of the interaction between the nervous and immune systems in both normal and diseased states. Understanding this interaction is fundamental to developing therapeutic approaches to disease and injury of the nervous system that are currently only marginally amenable to therapy. Neuroimmunology is a well-recognised and growing specialty world wide, both at the basic science and clinical level. It is a fast moving field and this is the most up to date text available. Chapters are dedicated to the role of the immune system in disorders affecting both the central and peripheral nervous systems, including important neurodegenerative diseases (such as multiple sclerosis and HIV-related neural degeneration) which cause life-long disability. Extensive coverage is given to a whole array of immune-directed therapies. The book has a strong international team of well respected, high profile editors and authors. The first edition published to extensive and positive reviews and has established itself as the principal reference source in the field. This second edition summarizes recent advances in clinical neuroimmunology in a comprehensive and unbiased way.
Author: Eilon Paz
Publisher: Ten Speed Press
ISBN: 1607748703
Category : Music
Languages : en
Pages : 577
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Book Description
A photographic look into the world of vinyl record collectors—including Questlove—in the most intimate of environments—their record rooms. Compelling photographic essays from photographer Eilon Paz are paired with in-depth and insightful interviews to illustrate what motivates these collectors to keep digging for more records. The reader gets an up close and personal look at a variety of well-known vinyl champions, including Gilles Peterson and King Britt, as well as a glimpse into the collections of known and unknown DJs, producers, record dealers, and everyday enthusiasts. Driven by his love for vinyl records, Paz takes us on a five-year journey unearthing the very soul of the vinyl community.
Author: Lutz Hein
Publisher: Springer Science & Business Media
ISBN: 9783540001096
Category : Medical
Languages : en
Pages : 692
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Book Description
Up-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilitated by tables, which list the most important genetically engineered animal models and their phenotypes. This book aims at illustrating the impact of transgenic animal models in the field of Experimental Pharmacology and Toxicology, which includes their role in the understanding of basic cellular mechanisms, the evaluation of potential drug targets or the testing for drug effects.
Author:
Publisher: Springer Science & Business Media
ISBN: 9783540428145
Category : Medical
Languages : en
Pages : 242
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Book Description
In this volume of Reviews there are three outstanding articles, one on phspholipase D, an enzyme that is widely distributed in bacteria, protozoa, fungi, plants and animals. Phospholipase D carries out a transphosphatidylation reaction, which is unique to this enzyme. This review is focussed on mammalian PLDs. The second review deals with endotoxin tolerance, the term which describes the phenomenon that immune responses and metabolic changes are mitigated after repeated LPS administration. The third article summarizes the current knowledge relevant to understanding the molecular basis of GPCR function and focusses on the underlying mechanisms of GPCR malfunctions responsible for diferent human diseases.
Author: C.E. Patterson
Publisher: Elsevier
ISBN: 0444518347
Category : Medical
Languages : en
Pages : 540
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Book Description
Covers endothelial biology from the fundamentals of structure and lung fluid balance physiology to descriptions of the molecular mechanisms involved in the development of lung failure. This illustrated text provides the knowledge of endothelial function, vascular integrity, pulmonary function, and pathophysiology in respiratory failure.
Author: James H. North
Publisher: Scarecrow Press
ISBN: 1461656443
Category : Music
Languages : en
Pages : 412
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Book Description
Andre Kostelanetz On Records and On the Air is a comprehensive discography of the commercial recordings of the Russian/American conductor and radio personality, Andre Kostelanetz. James H. North has collected all his recordings, spanning the range from popular to classical. Organized chronologically by album, North provides the complete details of each recording: composer, song title, timing, date and site of the recording session, producer of that session, and matrix numbers, as well as every American issue of each recording. Several appendixes organize the information alphabetically by composer, song title, and album title, giving references back to the discography by date of recording. Available downloads from the Internet are included in the song title appendix. Two further appendixes deal with Compact Disc issues and with V-Discs, the records created by the United States Army and Navy for worldwide distribution to members of the Armed Forces during World War II. Initially a request from the Andre Kostelanetz Estate, who has generously supported this work, the discography grew to include a complete coverage of Kostelanetz's appearances on the radio, from the 1920s through 1980 (plus a few on television), as North discovered that Kostelanetz's radio career was as important as his records to music in America. More than 1,000 broadcasts are covered, including both his radio shows and his concert broadcasts with symphony orchestras, and the contents of each program are listed where known. An important extra in the book is a survey of Kostelanetz's career and an evaluation of his achievements, contributed by noted radio historian Dick O'Connor. A foreword by the Archivist and Historian of the New York Philharmonic, Barbara Haws, completes this reference tool, which will be invaluable to the millions of fans who welcome the opportunity to peruse the details of one of the most beloved figures in music.
