Living Morphogenesis of the Heart

Living Morphogenesis of the Heart PDF Author: Roger Markwald
Publisher: Springer Science & Business Media
ISBN: 1461217881
Category : Medical
Languages : en
Pages : 245

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Book Description
The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lineage that progres sively and irreversibly assemble into a segmented, primary heart tube that can be remodeled into a four-chambered organ, and (2) how blood vessels are derived and assembled both in the heart and in the body. Our central aim is to establish a four-dimensional, spatiotemporal foundation for the heart and blood vessels that can be genetically dissected for function and mechanism. Since Robert DeHaan's seminal chapter "Morphogenesis of the Vertebrate Heart" published in Organogenesis (Holt Rinehart & Winston, NY) in 1965, there have been surprisingly few books devoted to the subject of cardiovascular morpho genesis, despite the enormous growth of interest that occurred nationally and internationally. Most writings on the subject have been scholarly compilations of the proceedings of major national or international symposia or muItiauthored volumes, often without a specific theme. What is missing are the unifying concepts that can make sense out of a burgeoning database of facts. The Editorial Board of this new series believes the time has come for a book series dedicated to cardiovas cular morphogenesis that will serve not only as an important archival and didactic reference source for those who have recently come into the field but also as a guide to the evolution of a field that is clearly coming of age.

Living Morphogenesis of the Heart

Living Morphogenesis of the Heart PDF Author: Roger Markwald
Publisher: Springer Science & Business Media
ISBN: 1461217881
Category : Medical
Languages : en
Pages : 245

Get Book Here

Book Description
The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lineage that progres sively and irreversibly assemble into a segmented, primary heart tube that can be remodeled into a four-chambered organ, and (2) how blood vessels are derived and assembled both in the heart and in the body. Our central aim is to establish a four-dimensional, spatiotemporal foundation for the heart and blood vessels that can be genetically dissected for function and mechanism. Since Robert DeHaan's seminal chapter "Morphogenesis of the Vertebrate Heart" published in Organogenesis (Holt Rinehart & Winston, NY) in 1965, there have been surprisingly few books devoted to the subject of cardiovascular morpho genesis, despite the enormous growth of interest that occurred nationally and internationally. Most writings on the subject have been scholarly compilations of the proceedings of major national or international symposia or muItiauthored volumes, often without a specific theme. What is missing are the unifying concepts that can make sense out of a burgeoning database of facts. The Editorial Board of this new series believes the time has come for a book series dedicated to cardiovas cular morphogenesis that will serve not only as an important archival and didactic reference source for those who have recently come into the field but also as a guide to the evolution of a field that is clearly coming of age.

Cardiac CT and MR for Adult Congenital Heart Disease

Cardiac CT and MR for Adult Congenital Heart Disease PDF Author: Farhood Saremi
Publisher: Springer Science & Business Media
ISBN: 1461488753
Category : Medical
Languages : en
Pages : 735

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Book Description
​​This is the first major textbook to address both computed tomography (CT) and magnetic resonance (MR) cardiac imaging of adults for the diagnosis and treatment of congenital heart disease (CHD). Since the introduction of faster CT scanners, there has been tremendous advancement in the diagnosis of CHD in adults. This is mostly due to the higher spatial resolution of CT compared to MR, which enables radiologists to create more detailed visualizations of cardiac anatomic structures, leading to the discovery of anomalous pathologies often missed by conventional MR imaging. This book is unique in highlighting the advantages of both CT and MR for the diagnosis of CHD in adults, focusing on the complementary collaboration between the two modalities that is possible. Chapters include discussions of case examples, clinical data, MR and CT image findings, and correlative cadaveric pictures. The chapters focus not only on the diagnosis of the primary problem, but also give readers information on visual clues to look for that often reveal associated pathologies. This book appeals primarily to diagnostic and interventional radiologists, as well as cardiologists and interventional cardiologists.

Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension

Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension PDF Author: Toshio Nakanishi
Publisher: Springer Nature
ISBN: 9811511853
Category : Medical
Languages : en
Pages : 374

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Book Description
This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.

Pathology of Heart Disease in the Fetus, Infant and Child

Pathology of Heart Disease in the Fetus, Infant and Child PDF Author: Michael T. Ashworth
Publisher: Cambridge University Press
ISBN: 1107116287
Category : Family & Relationships
Languages : en
Pages : 361

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Book Description
Clearly presents the pathology of heart disease from fetus to adolescence, integrating histology and macroscopy with effects of treatment.

Echocardiography in Pediatric and Congenital Heart Disease

Echocardiography in Pediatric and Congenital Heart Disease PDF Author: Wyman W. Lai
Publisher: John Wiley & Sons
ISBN: 1118337255
Category : Medical
Languages : en
Pages : 1618

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Book Description
Echocardiography is essential in the practice of pediatric cardiology. A clinical pediatric cardiologist is expected to be adept at the non-invasive diagnosis of congenital heart disease and those who plan to specialize in echocardiography will need to have knowledge of advanced techniques. Echocardiography in Pediatric and Congenital Heart Disease addresses the needs of trainees and practitioners in this field, filling a void caused by the lack of material in this fast-growing area. This new title comprehensively covers the echocardiographic assessment of congenital heart disease, from the fetus to the adult, plus acquired heart disease in children. Topics covered include: ultrasound physics laboratory set-up a protocol for a standard pediatric echocardiogram quantitative methods of echocardiographic evaluation, including assessment of diastolic function in depth coverage of congenital cardiovascular malformations acquired pediatric heart disease topics of special interest, such as 3D echocardiography, transesophageal echocardiography, and fetal echocardiography The approach of this book is a major advancement for educational materials in the field of pediatric cardiology, and greatly enhances the experience for the reader. An accompanying DVD with moving images of the subjects covered in the textbook will further enhance the learning experience.

Myofibrillogenesis

Myofibrillogenesis PDF Author: Dipak K. Dube
Publisher: Springer Science & Business Media
ISBN: 9780817642266
Category : Science
Languages : en
Pages : 304

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Book Description
Myofibrillogenesis has been studied extensively over the last 100 years. Until recently, we have not had a comprehensive understanding of this fundamental process. The emergence of new technologies in molecular and cellular biology, combined with classical embryology, have started to unravel some of the complexities of myofibril assembly in striated muscles. In striated muscles, the contractile proteins are arranged in a highly ordered three dimensional lattice known as the sarcomere. The assembly of a myofibril involves the precise ordering of several proteins into a linear array of sarcomeres. Multiple isoforms in many of these proteins further complicate the process, making it difficult to define the precise role of each component. This volume has been compiled as a comprehensive reference on myofibrillogenesis. In addition, the book includes reviews on myofibrillar disarray under various pathological conditions, such as familial hypertrophic cardiomyopathy (FHC), and incorporates a section on the conduction system in the heart. Much of the information in this volume has not been described elsewhere. Presented in a manner to be of value to students and teachers alike, "Myofibrillogenesis" will be an invaluable reference source for all in the fields of muscle biology and heart development.

Pediatric Cardiovascular Medicine

Pediatric Cardiovascular Medicine PDF Author: James H. Moller
Publisher: John Wiley & Sons
ISBN: 1444335898
Category : Medical
Languages : en
Pages : 1096

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Book Description
The first edition of this text, edited by two of the world’s most respected pediatric cardiologists, set the standard for a single-volume, clinically focused textbook on this subject. This new edition, revised and updated by contributors representing today’s global thought leaders, offers increased coverage of the most important current topics, such as pediatric electrophysiology, congenital heart disease, cardiovascular genetics/genomics, and the identification and management of risk factors in children, while maintaining the clinical focus. Published with a companion website that features additional images for download, self-assessment questions designed to aid readers who are preparing for examinations, and other features, Pediatric Cardiovascular Medicine, Second Edition, is the perfect reference for residents, fellows, pediatricians, as well as specialists in pediatric cardiology.

Formation of the Heart and its Regulation

Formation of the Heart and its Regulation PDF Author: Robert J. Tomanek
Publisher: Springer Science & Business Media
ISBN: 9780817642167
Category : Science
Languages : en
Pages : 306

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Book Description
The `Formation of the Heart and its Regulation` reviews in considerable detail the major events in heart development and their control via genes, cell-cell interactions, growth factors and other contributing elements. In addition, there is an extensive and useful overview of the field of heart development taken as a whole. The book will appeal to all students and researchers working on cardiovascular development and to pediatric cardiologists.

Heart Development

Heart Development PDF Author: Richard P. Harvey
Publisher: Gulf Professional Publishing
ISBN: 9780123298607
Category : Medical
Languages : en
Pages : 574

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Book Description
Contributors. -- Preface. -- C. Seidman, Introduction. -- I. Origins and Early Morphogenesis: -- P.P.L. Tam and G.C. Schoenwolf, Cardiac Fate Maps: Lineage Allocation, Morphogenetic Movement, and Cell Commitment. -- T. Mikawa, Cardiac Lineages. -- II. Cardiac Induction: -- T.J. Mohun and L.M. Leong, Heart Formation and the Heart Field in Amphibian Embryos. -- T.M. Schultheiss and A.B. Lassar, Vertebrate Heart Induction. -- III. Genetic Dissection of Heart Development: -- R. Bodmer and M. Frasch, Genetic Determination in Drosophilia Heart Development. -- J. Alexander and D.Y.R. Stainier, Mutations Affecting Cardiac Development in Zebrafish. -- R.P. Harvey, C. Biben, and D.A. Elliott, Transcriptional Control and Pattern Formation in the Developing Vertebrate Heart: Studies on NK-2 Class Homeodomain Factors. -- B.L. Black and E.N. Olson, Control of Cardiac Development by the Family of MEF2 Transcription Factors. -- D. Srivastava, Segmental Regulation of Cardiac Development by the Basic He ...

Fetal Therapy

Fetal Therapy PDF Author: Mark D. Kilby
Publisher: Cambridge University Press
ISBN: 1107012139
Category : Medical
Languages : en
Pages : 471

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Book Description
Covers the latest insights any fetal specialist needs and provides essential knowledge for professionals caring for women with high-risk pregnancies.