Literature-based Discovery

Literature-based Discovery PDF Author: Peter Bruza
Publisher: Springer Science & Business Media
ISBN: 3540686908
Category : Computers
Languages : en
Pages : 200

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Book Description
This is the first coherent book on literature-based discovery (LBD). LBD is an inherently multi-disciplinary enterprise. The aim of this volume is to plant a flag in the ground and inspire new researchers to the LBD challenge.

Literature-based Discovery

Literature-based Discovery PDF Author: Peter Bruza
Publisher: Springer Science & Business Media
ISBN: 3540686908
Category : Computers
Languages : en
Pages : 200

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Book Description
This is the first coherent book on literature-based discovery (LBD). LBD is an inherently multi-disciplinary enterprise. The aim of this volume is to plant a flag in the ground and inspire new researchers to the LBD challenge.

Trends and Applications in Knowledge Discovery and Data Mining

Trends and Applications in Knowledge Discovery and Data Mining PDF Author: Wei Lu
Publisher: Springer Nature
ISBN: 3030604705
Category : Computers
Languages : en
Pages : 195

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Book Description
This book constitutes the thoroughly refereed post-workshop proceedings of the workshops that were held in conjunction with the 24th Pacific-Asia Conference on Knowledge Discovery and Data Mining, PAKDD 2020, in Singapore, Singapore, in May 2020. The 17 revised full papers presented were carefully reviewed and selected from a total of 50 submissions. The five workshops were as follows: · First International Workshop on Literature-Based Discovery (LBD 2020) · Workshop on Data Science for Fake News (DSFN 2020) · Learning Data Representation for Clustering (LDRC 2020) · Ninth Workshop on Biologically Inspired Techniques for Data Mining (BDM · 2020) · First Pacific Asia Workshop on Game Intelligence & Informatics (GII 2020)

Public Knowledge, Private Ignorance

Public Knowledge, Private Ignorance PDF Author: Patrick Wilson
Publisher: Praeger
ISBN:
Category : Language Arts & Disciplines
Languages : en
Pages : 180

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Book Description
An examination of the role of libraries in the utilization of knowledge and in enhancing the informed conduct of life incorporates a review of the goals of library use and library services.

The Discovery of Slowness

The Discovery of Slowness PDF Author: Sten Nadolny
Publisher: Penguin
ISBN: 1101658096
Category : Fiction
Languages : en
Pages : 337

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Book Description
In The Discovery of Slowness, German novelist Sten Nadolny recounts the life of the nineteenth-century British explorer Sir John Franklin (1786-1847). The reader follows Franklin's development from awkward schoolboy and ridiculed teenager to expedition leader, governor of Tasmania, and icon of adventure. Everyone with whom he came into contact sensed that he was a rare man, one who was “out of his time” and who moved to a different, grander beat. That beat eventually led Franklin to sail once more—on his final, fateful voyage—into the Arctic in search of the Northwest Passage. The Discovery of Slowness is both a riveting account of a remarkable and varied life, and a profound and thought-provoking meditation on time.

Drug Discovery

Drug Discovery PDF Author: Jie Jack Li
Publisher: John Wiley & Sons
ISBN: 111835446X
Category : Medical
Languages : en
Pages : 572

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Book Description
Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design. Drug Discovery features chapters written by an international team of pharmaceutical and medicinal chemists. Contributions are based on a thorough review of the current literature as well as the authors' firsthand laboratory experience in drug discovery. The book begins with the history of drug discovery, describing groundbreaking moments in the field. Next, it covers such topics as: Target identification and validation Drug metabolism and pharmacokinetics Central nervous system drugs In vitro and in vivo assays Cardiovascular drugs Cancer drugs Each chapter features a case study, helping readers understand how science is put into practice throughout all phases of drug discovery. References at the end of each chapter serve as a gateway to groundbreaking original research studies and reviews in the field. Drug Discovery is ideal for newcomers to medicinal chemistry and drug discovery, providing a comprehensive overview of the field. Veterans in the field will also benefit from the perspectives of leading international experts in all aspects of drug discovery.

Reinventing Discovery

Reinventing Discovery PDF Author: Michael Nielsen
Publisher: Princeton University Press
ISBN: 0691202842
Category : Science
Languages : en
Pages : 272

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Book Description
"Reinventing Discovery argues that we are in the early days of the most dramatic change in how science is done in more than 300 years. This change is being driven by new online tools, which are transforming and radically accelerating scientific discovery"--

A Discovery of Witches

A Discovery of Witches PDF Author: Deborah Harkness
Publisher: Penguin
ISBN: 1101475692
Category : Fiction
Languages : en
Pages : 593

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Book Description
Book one of the New York Times bestselling All Souls series, from the author of The Black Bird Oracle. “A wonderfully imaginative grown-up fantasy with all the magic of Harry Potter and Twilight” (People). Look for the hit series “A Discovery of Witches,” now streaming on AMC+, Sundance Now, and Shudder! Deborah Harkness’s sparkling debut, A Discovery of Witches, has brought her into the spotlight and galvanized fans around the world. In this tale of passion and obsession, Diana Bishop, a young scholar and a descendant of witches, discovers a long-lost and enchanted alchemical manuscript, Ashmole 782, deep in Oxford's Bodleian Library. Its reappearance summons a fantastical underworld, which she navigates with her leading man, vampire geneticist Matthew Clairmont. Harkness has created a universe to rival those of Anne Rice, Diana Gabaldon, and Elizabeth Kostova, and she adds a scholar's depth to this riveting tale of magic and suspense. The story continues in book two, Shadow of Night, book three, The Book of Life, and the fourth in the series, Time’s Convert.

The Fourth Paradigm

The Fourth Paradigm PDF Author: Anthony J. G. Hey
Publisher:
ISBN:
Category : Computers
Languages : en
Pages : 292

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Book Description
Foreword. A transformed scientific method. Earth and environment. Health and wellbeing. Scientific infrastructure. Scholarly communication.

Textbook of Drug Design and Discovery, Third Edition

Textbook of Drug Design and Discovery, Third Edition PDF Author: Tommy Liljefors
Publisher: CRC Press
ISBN: 9780415282888
Category : Medical
Languages : en
Pages : 596

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Book Description
Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques, and combinatorial approaches are also included.

Process Mining

Process Mining PDF Author: Wil M. P. van der Aalst
Publisher: Springer
ISBN: 3662498510
Category : Computers
Languages : en
Pages : 477

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Book Description
This is the second edition of Wil van der Aalst’s seminal book on process mining, which now discusses the field also in the broader context of data science and big data approaches. It includes several additions and updates, e.g. on inductive mining techniques, the notion of alignments, a considerably expanded section on software tools and a completely new chapter of process mining in the large. It is self-contained, while at the same time covering the entire process-mining spectrum from process discovery to predictive analytics. After a general introduction to data science and process mining in Part I, Part II provides the basics of business process modeling and data mining necessary to understand the remainder of the book. Next, Part III focuses on process discovery as the most important process mining task, while Part IV moves beyond discovering the control flow of processes, highlighting conformance checking, and organizational and time perspectives. Part V offers a guide to successfully applying process mining in practice, including an introduction to the widely used open-source tool ProM and several commercial products. Lastly, Part VI takes a step back, reflecting on the material presented and the key open challenges. Overall, this book provides a comprehensive overview of the state of the art in process mining. It is intended for business process analysts, business consultants, process managers, graduate students, and BPM researchers.