LC-MS/MS Method for Mycotoxin Analysis

LC-MS/MS Method for Mycotoxin Analysis PDF Author: Aldo Laganà
Publisher: MDPI
ISBN: 3038426067
Category : Electronic books
Languages : en
Pages : 195

Get Book Here

Book Description
This book is a printed edition of the Special Issue "LC-MS/MS Method for Mycotoxin Analysis" that was published in Toxins

LC-MS/MS Method for Mycotoxin Analysis

LC-MS/MS Method for Mycotoxin Analysis PDF Author: Aldo Laganà
Publisher: MDPI
ISBN: 3038426067
Category : Electronic books
Languages : en
Pages : 195

Get Book Here

Book Description
This book is a printed edition of the Special Issue "LC-MS/MS Method for Mycotoxin Analysis" that was published in Toxins

LC-MS/MS Method for Mycotoxin Analysis

LC-MS/MS Method for Mycotoxin Analysis PDF Author: Aldo Laganà
Publisher:
ISBN: 9783038426073
Category :
Languages : en
Pages :

Get Book Here

Book Description
LC-MS/MS Method for Mycotoxin Analysis.

LC-MS/MS Method for Mycotoxin Analysis

LC-MS/MS Method for Mycotoxin Analysis PDF Author: Aldo Laganà (Ed.)
Publisher:
ISBN:
Category :
Languages : en
Pages :

Get Book Here

Book Description


Application of LC-MS/MS in the Mycotoxins Studies

Application of LC-MS/MS in the Mycotoxins Studies PDF Author: Laura Gámiz-Gracia
Publisher: MDPI
ISBN: 3039362062
Category : Science
Languages : en
Pages : 302

Get Book Here

Book Description
Mycotoxins are secondary metabolites produced by the fungi of different species (mainly Aspergillus, Fusarium, and Penicillium), with toxic effects for humans and animals. These mycotoxins can contaminate food and feed. The European Union (EU) has established the maximum permitted or recommended levels for well-known mycotoxins in different foodstuffs. However, there are other mycotoxins that are not included in the regulations: the “emerging mycotoxins” (whose toxicity is still not clear), and the “modified or masked mycotoxins” (produced as a consequence of a detoxification strategy of the host plant of the fungus or during food processing). These mycotoxins could pose a risk and should also be taken into account. In order to assure consumers’ health, analytical methods for the accurate determination of mycotoxins in different food matrices and feeds are required. In this sense, liquid chromatography tandem mass spectrometry (LC–MS/MS) is a powerful tool for their unique identification and quantification. Moreover, the use of high-resolution mass spectrometry (HRMS) allows one to identify novel mycotoxins and targeted/untargeted approaches for study. This Special Issue compiles recent applications of LC–MS/MS in mycotoxin studies, as well as the development and validation of new analytical methods for their identification and quantification in different food matrices and feed, occurrence studies, and the biomonitoring of mycotoxins and their metabolites in biological fluids.

Safety Evaluation of Certain Mycotoxins in Food

Safety Evaluation of Certain Mycotoxins in Food PDF Author: Joint FAO/WHO Expert Committee on Food Additives. Meeting
Publisher: Food & Agriculture Org.
ISBN: 9789251046647
Category : Aflatoxins
Languages : en
Pages : 712

Get Book Here

Book Description
This volume contains monographs prepared at the fifty-sixth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). Five mycotoxins or groups of mycotoxins that contaminate food commodities were evaluated at the meeting: aflatoxin M1, fumonisins B1, B2, and B3, ochratoxin A, deoxynivalenol, and T -2 and HT -2 toxins. The monographs in this volume summarize the data that were reviewed on these contaminants, including information on metabolism and toxicity, epidemiology, analytical methods for their measurement in food commodities, sampling protocols, effects of processing, levels and patterns of contamination of food commodities, food consumption, and prevention and control. Based upon this information the Committee assessed the risks associated with intake of these mycotoxins.

Applications of LC-MS in Toxicology

Applications of LC-MS in Toxicology PDF Author: Aldo Polettini
Publisher: Pharmaceutical Press
ISBN: 9780853696292
Category : Analytical toxicology
Languages : en
Pages : 310

Get Book Here

Book Description
Analytical toxicologists are involved in the analysis of drugs and poisons in biological samples in different environments. Many scientists in the field of analytical toxicology have adopted LC-MS in their daily work, and this is illustrated by the increasing numbers of research papers published and presented at relevant conferences.

Application of LC-MS/MS in the Mycotoxins Studies

Application of LC-MS/MS in the Mycotoxins Studies PDF Author: Laura Gámiz-Gracia
Publisher:
ISBN: 9783039362073
Category :
Languages : en
Pages : 302

Get Book Here

Book Description
Mycotoxins are secondary metabolites produced by the fungi of different species (mainly Aspergillus, Fusarium, and Penicillium), with toxic effects for humans and animals. These mycotoxins can contaminate food and feed. The European Union (EU) has established the maximum permitted or recommended levels for well-known mycotoxins in different foodstuffs. However, there are other mycotoxins that are not included in the regulations: the “emerging mycotoxins” (whose toxicity is still not clear), and the “modified or masked mycotoxins” (produced as a consequence of a detoxification strategy of the host plant of the fungus or during food processing). These mycotoxins could pose a risk and should also be taken into account. In order to assure consumers' health, analytical methods for the accurate determination of mycotoxins in different food matrices and feeds are required. In this sense, liquid chromatography tandem mass spectrometry (LC-MS/MS) is a powerful tool for their unique identification and quantification. Moreover, the use of high-resolution mass spectrometry (HRMS) allows one to identify novel mycotoxins and targeted/untargeted approaches for study. This Special Issue compiles recent applications of LC-MS/MS in mycotoxin studies, as well as the development and validation of new analytical methods for their identification and quantification in different food matrices and feed, occurrence studies, and the biomonitoring of mycotoxins and their metabolites in biological fluids.

Modern Methods in the Analysis and Structural Elucidation of Mycotoxins

Modern Methods in the Analysis and Structural Elucidation of Mycotoxins PDF Author: Richard J. Cole
Publisher: Elsevier
ISBN: 0323148530
Category : Science
Languages : en
Pages : 487

Get Book Here

Book Description
Modern Methods in the Analysis and Structural Elucidation of Mycotoxins presents available methods of analysis and structural elucidation of mycotoxins by recognized experts in the various disciplines. The approach in each chapter of the book is to present each method initially in theoretical terms and then to review the method as it specifically applies to the analysis and/or structural elucidation of mycotoxins. Comprised of 15 chapters, the book's opening chapters deal with screening, sampling, and survey methods for mycotoxins and toxigenic fungi. This is followed by chapters dealing mostly with methods for structural elucidation, such as NMR and X-ray crystallography and IR and UV spectroscopy, as well as biosynthetic techniques. Significant chapters consider the analytical methods for mycotoxin analyses, including enzyme-linked immunosorbent assay system and tandem mass spectrometry. The concluding chapter examines the mycotoxin analytical problem in taxonomic or ecological terms. This book is of value to food and feed researchers, scientists, and manufacturers who are interested in product contamination control.

Masked Mycotoxins in Food

Masked Mycotoxins in Food PDF Author: Chiara Dall'Asta
Publisher: Royal Society of Chemistry
ISBN: 1782622578
Category : Medical
Languages : en
Pages : 222

Get Book Here

Book Description
The first book to cover this fast developing field, Masked Mycotoxins in Food will provide a full overview of the issues relating to the toxicology of masked mycotoxins present in food products. Mycotoxins are naturally occurring chemicals produced by moulds that can grow on crops and foodstuffs. Masked mycotoxins are modified mycotoxins, due to this modification many cannot be detected using standard analytical techniques, for example HPLC and ELISA, and further research is needed to understand the health risks and threats from these modified compounds.Masked mycotoxin research is an area of toxicological research that has gained significant interest and momentum in recent years. The aim of this book is to provide a full picture of the topic, from the masked mycotoxin formation in plants to their catabolic fate in humans. The book also provides new insights and will highlight possible gaps in the knowledge base of this relatively new area. Edited and written by World renowned experts working within the field, this book is of interest to toxicologists and biochemists, but also food scientists and agricultural researchers working in industry and academia.

Determining Mycotoxins and Mycotoxigenic Fungi in Food and Feed

Determining Mycotoxins and Mycotoxigenic Fungi in Food and Feed PDF Author: Sarah De Saeger
Publisher: Elsevier
ISBN: 0857090976
Category : Technology & Engineering
Languages : en
Pages : 452

Get Book Here

Book Description
Mycotoxins - toxic secondary metabolites produced by mycotoxigenic fungi – pose a significant risk to the food chain. Indeed, they may be the most hazardous of all food contaminants in terms of chronic toxicity and legislative limits on their levels in food and feed continue to be developed worldwide. Rapid and reliable methods for the determination of both mycotoxigenic fungi and mycotoxins in food and feed are therefore essential. This book reviews current and emerging methods in this area.Part one focuses on the essentials of mycotoxin determination, covering sampling, sample preparation and clean-up and key determination techniques, such as chromatographic separation, liquid chromatography-mass spectrometry and immunochemical methods. Part two then goes on to describe quality assurance, official methods and performance criteria for determining mycotoxins in food and feed. Topics covered include laboratory accreditation, method validation and measurement uncertainty. The development and analysis of biomarkers for mycotoxins are discussed in part three. Individual chapters focus on detecting exposure in humans and animals. Part four is concerned with the processes involved in determining mycotoxigenic fungi in food and feed. It also describes the identification of genes and gene clusters involved in mycotoxin synthesis, as well as DNA barcoding of toxigenic fungi. Finally, part five explores some of the emerging methods for mycotoxin analysis, ranging from bio-sensing to spectroscopic techniques.With its distinguished editor and international team of contributors, Determining mycotoxins and mycotoxigenic fungi in food and feed is a standard reference for all those concerned with reducing mycotoxin contamination in the food chain. Focuses on the essentials of mycotoxin determination, covering sampling, sample preparation, clean-up and key determination techniques Documents quality assurance and official methods and performance criteria for determining mycotoxins in food and feed Explores the processes of determining mycotoxigenic fungi in food and feed including the identification of genes and gene clusters