Author: Kevin Lajiness
Publisher: Kevin Lajiness
ISBN:
Category :
Languages : en
Pages : 112
Book Description
Happy New Year, all Done. The Good, The Bad , and The Ugly. I cant help but think I'm hurting myself by putting this Book out because my later stuff is defiantly better and I'm not talking about my English. But my purpose is to put out an inclusive book with all my songs and videos, a depository if you will of everything, eventually it will be in order, and maybe a mega drop down menu. My latest stuff it's at ReverbNation, a player's on this page or in these pages. A Few other things, my voice is getting better from the radiation due to throat cancer, but its taking a long time and its not consistent. The fact that I have put out these songs after having had throat and neck cancer justifies to me that some may smell but they will never stink, besides for me it takes just as much to do a bad song/video than a good one . I put the same amount of heart in them. Also remember my stuff is Alternative, Alternative. I use music loops and combine things in a unconventional way, totally Naive, Just like my Art and me. I like to break free from convention and political correctness. For me art is a philosophical pattern of ones own expressions. Most of Mine are simple some Loud.
Kevin Lajiness 2009 Song Book
Author: Kevin Lajiness
Publisher: Kevin Lajiness
ISBN:
Category :
Languages : en
Pages : 112
Book Description
Happy New Year, all Done. The Good, The Bad , and The Ugly. I cant help but think I'm hurting myself by putting this Book out because my later stuff is defiantly better and I'm not talking about my English. But my purpose is to put out an inclusive book with all my songs and videos, a depository if you will of everything, eventually it will be in order, and maybe a mega drop down menu. My latest stuff it's at ReverbNation, a player's on this page or in these pages. A Few other things, my voice is getting better from the radiation due to throat cancer, but its taking a long time and its not consistent. The fact that I have put out these songs after having had throat and neck cancer justifies to me that some may smell but they will never stink, besides for me it takes just as much to do a bad song/video than a good one . I put the same amount of heart in them. Also remember my stuff is Alternative, Alternative. I use music loops and combine things in a unconventional way, totally Naive, Just like my Art and me. I like to break free from convention and political correctness. For me art is a philosophical pattern of ones own expressions. Most of Mine are simple some Loud.
Publisher: Kevin Lajiness
ISBN:
Category :
Languages : en
Pages : 112
Book Description
Happy New Year, all Done. The Good, The Bad , and The Ugly. I cant help but think I'm hurting myself by putting this Book out because my later stuff is defiantly better and I'm not talking about my English. But my purpose is to put out an inclusive book with all my songs and videos, a depository if you will of everything, eventually it will be in order, and maybe a mega drop down menu. My latest stuff it's at ReverbNation, a player's on this page or in these pages. A Few other things, my voice is getting better from the radiation due to throat cancer, but its taking a long time and its not consistent. The fact that I have put out these songs after having had throat and neck cancer justifies to me that some may smell but they will never stink, besides for me it takes just as much to do a bad song/video than a good one . I put the same amount of heart in them. Also remember my stuff is Alternative, Alternative. I use music loops and combine things in a unconventional way, totally Naive, Just like my Art and me. I like to break free from convention and political correctness. For me art is a philosophical pattern of ones own expressions. Most of Mine are simple some Loud.
Kevin Lajiness 2012 Song Book
Author: Kevin Lajiness
Publisher: Kevin Lajiness
ISBN:
Category : Music
Languages : en
Pages : 30
Book Description
I write from a position of emotion and honesty, usually tell a story about love, life, relationships, nature, adventure, history, spirituality,philosophy etc. My Art and Music style is Naive, I beat mix looped instruments as accompaniments but the melodies don't necessarily match, but I put a great deal of thought into them and try and bring something epic to bear in mind, yet some of my songs are ballads and relaxing songs of love .
Publisher: Kevin Lajiness
ISBN:
Category : Music
Languages : en
Pages : 30
Book Description
I write from a position of emotion and honesty, usually tell a story about love, life, relationships, nature, adventure, history, spirituality,philosophy etc. My Art and Music style is Naive, I beat mix looped instruments as accompaniments but the melodies don't necessarily match, but I put a great deal of thought into them and try and bring something epic to bear in mind, yet some of my songs are ballads and relaxing songs of love .
Kevin Lajiness 2011 Song Book
Author: Kevin Lajiness
Publisher: Kevin Lajiness
ISBN:
Category : Music
Languages : en
Pages : 43
Book Description
The Titles say it all, a little bit of a hodgepodge of Albums though, even though the songs in each album are mostly alike, "Angel Woman" is what you would expect as well as "Title Treaty and Laws Featuring harrier Hawk" and Epic Shine is still my most Epic song.
Publisher: Kevin Lajiness
ISBN:
Category : Music
Languages : en
Pages : 43
Book Description
The Titles say it all, a little bit of a hodgepodge of Albums though, even though the songs in each album are mostly alike, "Angel Woman" is what you would expect as well as "Title Treaty and Laws Featuring harrier Hawk" and Epic Shine is still my most Epic song.
Kevin Lajiness 2013-2014 Song Book
Author: Kevin Lajiness
Publisher: Kevin Lajiness
ISBN:
Category : Music
Languages : en
Pages : 28
Book Description
So far in 2013-14 I've written and produced four albums and am working on a fifth. Two; "The river" and "Charleena" in 2013 and "The King of The Fire", and "once Upon a Perfect Storm" in 2014, and am working on "I'm in Love With a Dream". Many of my songs are ballads with a natural order theme to them, I try to put meaning to them , tell a story or have the listener stop and take pause. There is a pattern or creative reality expressed in many of them with a philosophical alignment to Native cultures. Subjects include stuff like Eagles ,Rivers ,Storms ,Dreams, Battle, Love, Spirit, Fire, Wonder, Life, Epic Adventure, and Overcoming or Conquering adversity through Natural Living. I find myself in agreement with native philosophy and teachings
Publisher: Kevin Lajiness
ISBN:
Category : Music
Languages : en
Pages : 28
Book Description
So far in 2013-14 I've written and produced four albums and am working on a fifth. Two; "The river" and "Charleena" in 2013 and "The King of The Fire", and "once Upon a Perfect Storm" in 2014, and am working on "I'm in Love With a Dream". Many of my songs are ballads with a natural order theme to them, I try to put meaning to them , tell a story or have the listener stop and take pause. There is a pattern or creative reality expressed in many of them with a philosophical alignment to Native cultures. Subjects include stuff like Eagles ,Rivers ,Storms ,Dreams, Battle, Love, Spirit, Fire, Wonder, Life, Epic Adventure, and Overcoming or Conquering adversity through Natural Living. I find myself in agreement with native philosophy and teachings
Kevin Lajiness 2010 Song Book
Author: Kevin Lajiness
Publisher: Kevin Lajiness
ISBN:
Category : Music
Languages : en
Pages : 80
Book Description
In 2010 I spent allot of time spent writing songs and singing them in my car when people weren't around at the open spaces around Linwood NJ where i live, mostly on the edge of the wetlands, the songs have a natural flavor to them and are deep and i hope well thought out.
Publisher: Kevin Lajiness
ISBN:
Category : Music
Languages : en
Pages : 80
Book Description
In 2010 I spent allot of time spent writing songs and singing them in my car when people weren't around at the open spaces around Linwood NJ where i live, mostly on the edge of the wetlands, the songs have a natural flavor to them and are deep and i hope well thought out.
De novo Molecular Design
Author: Gisbert Schneider
Publisher: John Wiley & Sons
ISBN: 3527677038
Category : Medical
Languages : en
Pages : 540
Book Description
Systematically examining current methods and strategies, this ready reference covers a wide range of molecular structures, from organic-chemical drugs to peptides, Proteins and nucleic acids, in line with emerging new drug classes derived from biomacromolecules. A leader in the field and one of the pioneers of this young discipline has assembled here the most prominent experts from across the world to provide first-hand knowledge. While most of their methods and examples come from the area of pharmaceutical discovery and development, the approaches are equally applicable for chemical probes and diagnostics, pesticides, and any other molecule designed to interact with a biological system. Numerous images and screenshots illustrate the many examples and method descriptions. With its broad and balanced coverage, this will be the firststop resource not only for medicinal chemists, biochemists and biotechnologists, but equally for bioinformaticians and molecular designers for many years to come. From the content: * Reaction-driven de novo design * Adaptive methods in molecular design * Design of ligands against multitarget profiles * Free energy methods in ligand design * Fragment-based de novo design * Automated design of focused and target family-oriented compound libraries * Molecular de novo design by nature-inspired computing * 3D QSAR approaches to de novo drug design * Bioisosteres in de novo design * De novo design of peptides, proteins and nucleic acid structures, including RNA aptamers and many more.
Publisher: John Wiley & Sons
ISBN: 3527677038
Category : Medical
Languages : en
Pages : 540
Book Description
Systematically examining current methods and strategies, this ready reference covers a wide range of molecular structures, from organic-chemical drugs to peptides, Proteins and nucleic acids, in line with emerging new drug classes derived from biomacromolecules. A leader in the field and one of the pioneers of this young discipline has assembled here the most prominent experts from across the world to provide first-hand knowledge. While most of their methods and examples come from the area of pharmaceutical discovery and development, the approaches are equally applicable for chemical probes and diagnostics, pesticides, and any other molecule designed to interact with a biological system. Numerous images and screenshots illustrate the many examples and method descriptions. With its broad and balanced coverage, this will be the firststop resource not only for medicinal chemists, biochemists and biotechnologists, but equally for bioinformaticians and molecular designers for many years to come. From the content: * Reaction-driven de novo design * Adaptive methods in molecular design * Design of ligands against multitarget profiles * Free energy methods in ligand design * Fragment-based de novo design * Automated design of focused and target family-oriented compound libraries * Molecular de novo design by nature-inspired computing * 3D QSAR approaches to de novo drug design * Bioisosteres in de novo design * De novo design of peptides, proteins and nucleic acid structures, including RNA aptamers and many more.
Lead-Seeking Approaches
Author: Matthew M. Hayward
Publisher: Springer Science & Business Media
ISBN: 364201075X
Category : Science
Languages : en
Pages : 224
Book Description
High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery. The process for the identi?cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus compounds) or a more focused screen of a smaller set of compounds that have been preselected for the target of interest. Virtual screening methods such as structure-based or pharmacophore-based searches can complement or replace one of the above approaches. Once hits are identi?ed from one or more of these screening methods, they need to be thoroughly characterized in order to con?rm activity and identify areas in need of optimization. Finally, once fully characterized hits are identi?ed, preliminary optimization through synthetic modi?cation is carried out to generate leads. Parallel optimization of all properties, including biological, physicochemical, and ADME is the most ef?cient approach to the identi?cation of leads. Hit characterization is described in the previous chapter. The focus of this chapter is on hit optimization and the identi?- tion of leads. After a general overview of these processes, examples taken from the literature since 2001 will be used to illustrate speci?c points. There are also a number of excellent reviews covering the lead identi?cation process [1–6].
Publisher: Springer Science & Business Media
ISBN: 364201075X
Category : Science
Languages : en
Pages : 224
Book Description
High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery. The process for the identi?cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus compounds) or a more focused screen of a smaller set of compounds that have been preselected for the target of interest. Virtual screening methods such as structure-based or pharmacophore-based searches can complement or replace one of the above approaches. Once hits are identi?ed from one or more of these screening methods, they need to be thoroughly characterized in order to con?rm activity and identify areas in need of optimization. Finally, once fully characterized hits are identi?ed, preliminary optimization through synthetic modi?cation is carried out to generate leads. Parallel optimization of all properties, including biological, physicochemical, and ADME is the most ef?cient approach to the identi?cation of leads. Hit characterization is described in the previous chapter. The focus of this chapter is on hit optimization and the identi?- tion of leads. After a general overview of these processes, examples taken from the literature since 2001 will be used to illustrate speci?c points. There are also a number of excellent reviews covering the lead identi?cation process [1–6].
Novel Antischizophrenia Treatments
Author: Mark A. Geyer
Publisher: Springer Science & Business Media
ISBN: 3642257577
Category : Medical
Languages : en
Pages : 456
Book Description
This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume will concentrate on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
Publisher: Springer Science & Business Media
ISBN: 3642257577
Category : Medical
Languages : en
Pages : 456
Book Description
This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume will concentrate on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
Textbook of Clinical Neuropsychology
Author: Joel E. Morgan
Publisher: Taylor & Francis
ISBN: 1134982054
Category : Psychology
Languages : en
Pages : 2263
Book Description
Containing 50 chapters by some of the most prominent clinical neuropsychologists, the Textbook of Clinical Neuropsychology sets a new standard in the field in its scope, breadth, and scholarship. Unlike most other books in neuropsychology, the Textbook is organized primarily around syndromes, disorders, and related clinical phenomena. Written for the clinician at all levels of training, from the beginner to the journeyman, the Textbook presents contemporary clinical neuropsychology in a comprehensive volume. Chapters are rich with reviews of the literature and clinical case material spanning a range from pediatric to adult and geriatric disorders. Chapter authors are among the most respected in their field, leaders of American Neuropsychology, known for their scholarship and professional leadership. Rarely have so many distinguished members of one discipline been in one volume. This is essential reading for students of neuropsychology, and all others preparing for careers in the field.
Publisher: Taylor & Francis
ISBN: 1134982054
Category : Psychology
Languages : en
Pages : 2263
Book Description
Containing 50 chapters by some of the most prominent clinical neuropsychologists, the Textbook of Clinical Neuropsychology sets a new standard in the field in its scope, breadth, and scholarship. Unlike most other books in neuropsychology, the Textbook is organized primarily around syndromes, disorders, and related clinical phenomena. Written for the clinician at all levels of training, from the beginner to the journeyman, the Textbook presents contemporary clinical neuropsychology in a comprehensive volume. Chapters are rich with reviews of the literature and clinical case material spanning a range from pediatric to adult and geriatric disorders. Chapter authors are among the most respected in their field, leaders of American Neuropsychology, known for their scholarship and professional leadership. Rarely have so many distinguished members of one discipline been in one volume. This is essential reading for students of neuropsychology, and all others preparing for careers in the field.
Natural Products
Author: Lixin Zhang
Publisher: Springer Science & Business Media
ISBN: 1592599761
Category : Medical
Languages : en
Pages : 380
Book Description
A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
Publisher: Springer Science & Business Media
ISBN: 1592599761
Category : Medical
Languages : en
Pages : 380
Book Description
A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.