Joining and Assembly of Medical Materials and Devices

Joining and Assembly of Medical Materials and Devices PDF Author: Y N Zhou
Publisher: Elsevier
ISBN: 0857096427
Category : Medical
Languages : en
Pages : 583

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Book Description
As medical devices become more intricate, with an increasing number of components made from a wide range of materials, it is important that they meet stringent requirements to ensure that they are safe to be implanted and will not be rejected by the human body. Joining and assembly of medical materials and devices provides a comprehensive overview of joining techniques for a range of medical materials and applications.Part one provides an introduction to medical devices and joining methods with further specific chapters on microwelding methods in medical components and the effects of sterilization on medical materials and welded devices. Part two focuses on medical metals and includes chapters on the joining of shape memory alloys, platinum (Pt) alloys and stainless steel wires for implantable medical devices and evaluating the corrosion performance of metal medical device welds. Part three moves on to highlight the joining and assembly of medical plastics and discusses techniques including ultrasonic welding, transmission laser welding and radio frequency (RF)/dielectric welding. Finally, part four discusses the joining and assembly of biomaterial and tissue implants including metal-ceramic joining techniques for orthopaedic applications and tissue adhesives and sealants for surgical applications.Joining and assembly of medical materials and devices is a technical guide for engineers and researchers within the medical industry, professionals requiring an understanding of joining and assembly techniques in a medical setting, and academics interested in this field. - Introduces joining methods in medical applications including microwelding and considers the effects of sterilization on the resulting joints and devices - Considers the joining, assembly and corrosion performance of medical metals including shape memory alloys, platinum alloys and stainless steel wires - Considers the joining and assembly of medical plastics including multiple welding methods, bonding strategies and adhesives

Joining and Assembly of Medical Materials and Devices

Joining and Assembly of Medical Materials and Devices PDF Author: Y N Zhou
Publisher: Elsevier
ISBN: 0857096427
Category : Medical
Languages : en
Pages : 583

Get Book Here

Book Description
As medical devices become more intricate, with an increasing number of components made from a wide range of materials, it is important that they meet stringent requirements to ensure that they are safe to be implanted and will not be rejected by the human body. Joining and assembly of medical materials and devices provides a comprehensive overview of joining techniques for a range of medical materials and applications.Part one provides an introduction to medical devices and joining methods with further specific chapters on microwelding methods in medical components and the effects of sterilization on medical materials and welded devices. Part two focuses on medical metals and includes chapters on the joining of shape memory alloys, platinum (Pt) alloys and stainless steel wires for implantable medical devices and evaluating the corrosion performance of metal medical device welds. Part three moves on to highlight the joining and assembly of medical plastics and discusses techniques including ultrasonic welding, transmission laser welding and radio frequency (RF)/dielectric welding. Finally, part four discusses the joining and assembly of biomaterial and tissue implants including metal-ceramic joining techniques for orthopaedic applications and tissue adhesives and sealants for surgical applications.Joining and assembly of medical materials and devices is a technical guide for engineers and researchers within the medical industry, professionals requiring an understanding of joining and assembly techniques in a medical setting, and academics interested in this field. - Introduces joining methods in medical applications including microwelding and considers the effects of sterilization on the resulting joints and devices - Considers the joining, assembly and corrosion performance of medical metals including shape memory alloys, platinum alloys and stainless steel wires - Considers the joining and assembly of medical plastics including multiple welding methods, bonding strategies and adhesives

Cardiac Regeneration and Repair

Cardiac Regeneration and Repair PDF Author: Ren-Ke Li
Publisher: Elsevier
ISBN: 0857096702
Category : Science
Languages : en
Pages : 459

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Book Description
Cardiac Regeneration and Repair, Volume One reviews the pathology of cardiac injury and the latest advances in cell therapy. Chapters in part one explore the pathogenesis of congestive heart failure, the mechanisms responsible for adverse cardiac matrix remodeling, and potential interventions to restore ventricular function. Part two highlights new approaches to cell therapy for cardiac regeneration, and includes chapters covering alternative routes of cell delivery, monitoring cell engraftment, and the feasibility of using allogeneic stem cells to restore cardiac function. Chapters in part three move on to highlight novel stem cells for cardiac repair, including human embryonic stem cells and human pluripotent stem cells, and detail their current status and future potential for cardiac therapy. Finally, part four explores gene therapy, and includes ultrasound-targeted or direct gene delivery as well as cell-based gene therapy for cardiac regeneration. Cardiac Regeneration and Repair, Volume One is complemented by a second volume covering biomaterials and tissue engineering. Together, the two volumes of Cardiac Regeneration and Repair provide a comprehensive resource for clinicians, scientists, or academicians fascinated with cardiac regeneration, including those interested in cell therapy, tissue engineering, or biomaterials. - Explores the pathogenesis of congestive heart failure, the mechanisms responsible for adverse cardiac matrix remodeling, and potential interventions to restore ventricular function - Highlights new approaches to cell therapy for cardiac regeneration and includes chapters covering alternative routes of cell delivery, monitoring cell engraftment, and the feasibility of using allogeneic stem cells to restore cardiac function - Explores gene therapy and includes ultrasound-targeted or direct gene delivery as well as cell-based gene therapy for cardiac regeneration

Surface Coating and Modification of Metallic Biomaterials

Surface Coating and Modification of Metallic Biomaterials PDF Author: Cuie Wen
Publisher: Woodhead Publishing
ISBN: 1782423168
Category : Technology & Engineering
Languages : en
Pages : 449

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Book Description
Despite advances in alternative materials, metals are still the biomaterial of choice for a number of clinical applications such as dental, orthopedic and cardiac implants. However, there are a number of intrinsic problems associated with implanting metal in the biological environment, such as wear, corrosion, biocompatibility and toxicity, which must be addressed. Modern technology has enabled scientists to modify metal surfaces or apply special coatings to metals to improve their performance safety. Surface Coating and Modification of Metallic Biomaterials will discuss the most important modification techniques and coatings for metals, first covering the fundamentals of metals as a biomaterial and then exploring surface modification techniques and coatings. - An expansive overview of surface modification techniques for biomedical use - In-depth exploration of issues arising from metal biomaterial use - Includes examples of applications in a clinical setting

Shoulder and Elbow Trauma and its Complications

Shoulder and Elbow Trauma and its Complications PDF Author: Michael Greiwe
Publisher: Woodhead Publishing
ISBN: 1782424725
Category : Science
Languages : en
Pages : 506

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Book Description
Traumatic injuries to the shoulder remain a problem encountered by young and old alike. Trauma surgeons and shoulder and elbow specialists are called upon daily to improve the quality of life of injured individuals by restoring function, decreasing pain and returning individuals to their previous occupations and places in society. Such treatment provides both humanitarian and economic impact. Only recently have techniques and technology allowed surgeons to restore lives to such a degree following these injuries. Still, shoulder and elbow trauma remains a vexing problem for patients and surgeons alike. Many injuries result in lost work and serious debility including lack of function, post-traumatic arthritis and pain. This important textbook provides a systematic and comprehensive guide to the different types of shoulder trauma and the management of its associated complications. In Part One, the focus is on the most common types of shoulder trauma, with chapters covering anterior instability, traumatic rotator cuff tears, fractures, joint injuries and the floating shoulder and includes sections on the most common complications befalling each injury. Part II then reviews the management of the most common complications. Chapters include detailed analyses of persistent anterior shoulder instability, several forms of nonunion and malunion, failed acromioclavicular joint reconstruction, post-traumatic arthropathy and traumatic osteonecrosis, and failed arthroplasty for fracture. - Reviews common types of shoulder trauma - Addresses the common complications associated with each injury - Provides a detailed guide to the management of common complications

Functional Marine Biomaterials

Functional Marine Biomaterials PDF Author: Se-Kwon Kim
Publisher: Elsevier
ISBN: 1782420940
Category : Medical
Languages : en
Pages : 169

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Book Description
Functional Marine Biomaterials: Properties and Applications provides readers with the latest information on the diverse marine environment as a resource for many new substances, including biopolymers, bioceramics, and biominerals. As recent advances and funding has enabled scientists to begin harnessing many of these materials for biomedical applications from drug delivery to bone tissue engineering and biosensors, this important new text provides readers with a comprehensive review of these materials and their functional applications in the biomedical field. Chapters discuss the properties of the main classes of functional marine biomaterials, applications of marine products in tissue engineering, applications in drug delivery systems, and the role of marine derived materials in medical devices. - Provides readers with the latest information on the diverse marine environment as a resource for many new substances, including biopolymers, bioceramics, and biominerals - Presents a comprehensive review of these materials and their functional applications in the biomedical field - Discusses the properties of the main classes of functional marine biomaterials, applications of marine products in tissue engineering, applications in drug delivery systems, and the role of marine derived materials in medical devices

Surgical Techniques in Total Knee Arthroplasty and Alternative Procedures

Surgical Techniques in Total Knee Arthroplasty and Alternative Procedures PDF Author: Saverio Affatato
Publisher: Elsevier
ISBN: 178242038X
Category : Science
Languages : en
Pages : 299

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Book Description
Total knee arthroplasty (TKA) is commonly considered to be a reliable procedure, with high implant survival rates at 10 to 15 years of follow-up. The goal of total knee replacement surgery is to relieve pain and obtain better knee function. This is achieved by ensuring correct patient selection, pre-operative deformity, implant design and accurate surgical techniques. This book covers a range of techniques for the realisation of functional joint motion and stability. The first part of the book will describe fundamentals in total knee arthroplasty and alternative procedures. The second half will look at surgical techniques and considerations whilst the final chapters will address future trends and challenges in the field of knee surgery. This book will be an essential reference for academics, orthopaedic surgeons, and those training in medicine, physiatry and rheumatology.

Biomaterials and Medical Tribology

Biomaterials and Medical Tribology PDF Author: J. Paulo Davim
Publisher: Elsevier
ISBN: 0857092200
Category : Medical
Languages : en
Pages : 490

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Book Description
Medical tribology can be defined as the science of tribological phenomena in the human body, both those that naturally occur in the tissues or organs and those that arise after implantation of an artificial device, while biomaterials are inert substances designed to be incorporated into living systems. Biomaterials and medical tribology brings together a collection of high quality articles and case studies focussing on new research and developments in these two important fields.The book provides details of the different types of biomaterial available and their applications, including nanoparticles for biomedical applications, synergism effects during fiction and fretting corrosion experiments, application of biomedical-grade titanium alloys in trabecular bone and artificial joints, fatigue strengthening of an orthopaedic Ti6AI4V alloy, wear determination on retrieved metal-on-metal hip arthoplasty, natural articular joints, the importance of bearing porosity in engineering and natural lubrication, tribological characterization of human tooth enamel, and finally, liposome-based carrier systems and devices used for pulmonary drug delivery.Biomaterials and medical tribology is an essential reference for materials scientists, engineers, and researchers in the field of medical tribology. The title also provides an overview for academics and clinicians in this area.

Standardisation in Cell and Tissue Engineering

Standardisation in Cell and Tissue Engineering PDF Author: V Salih
Publisher: Elsevier
ISBN: 0857098721
Category : Science
Languages : en
Pages : 282

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Book Description
The increased use of biodegradable synthetic or natural scaffolds combined with cells and/or biological molecules, in order to create functional replacement tissue in a damaged tissue site, has led to the need for the development of 'best practice' methods in the area of tissue engineering to help ensure the creation of safe, high quality products. Standardisation in cell and tissue engineering introduces concepts and current practice in the field of cell and tissue engineering to a wide audience and aims to provide awareness of the importance of standardisation in this area while suggesting directions for further investigation.Part one provides an overview of methods for cell and tissue engineering and includes chapters on the fundamentals of cell and matrix biology for tissue engineering, 3D collagen biomatrix development, and control and vascularisation of tissue-engineered constructs. Part two begins with a chapter exploring the methods and protocols of standardisation in cell and tissue engineering before moving on to highlight issues of quality control in cell and tissue engineering, standardised chemical analysis and testing of biomaterials and principles of good laboratory practice (GLP) for in vitro cell culture applications.Standardisation in cell and tissue engineering is a standard reference for leading research groups, government agencies, regulatory bodies, and researchers and technicians at all levels across the whole range of disciplines using cell culture within the pharmaceutical, biotechnology and biomedical industries. - Introduces concepts and current practice in the field of cell and tissue engineering - Highlights the importance of standardisation in cell and tissue engineering and suggests directions for further investigation - Explores methods and protocols of standardisation in cell and tissue engineering and issues of quality control in cell and tissue engineering

Regenerative Engineering of Musculoskeletal Tissues and Interfaces

Regenerative Engineering of Musculoskeletal Tissues and Interfaces PDF Author: Syam Nukavarapu
Publisher: Woodhead Publishing
ISBN: 1782423141
Category : Science
Languages : en
Pages : 463

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Book Description
Repair and regeneration of musculoskeletal tissues is generating substantial interest within the biomedical community. Consequently, these are the most researched tissues from the regeneration point of view. Regenerative Engineering of Musculoskeletal Tissues and Interfaces presents information on the fundamentals, progress and recent developments related to the repair and regeneration of musculoskeletal tissues and interfaces. This comprehensive review looks at individual tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of cells, growth factors, and mechanical forces, moving on to discuss tissue-engineering strategies for bone, tendon, ligament, cartilage, meniscus, and muscle, as well as progress and advances in tissue vascularization and nerve innervation of the individual tissues. Final chapters present information on musculoskeletal tissue interfaces. - Comprehensive review of the repair and regeneration of musculoskeletal individual tissues and tissue interfaces - Presents recent developments, fundamentals and progress in the field of engineering tissues - Reviews progress and advances in tissue vascularization and innervation

Hydroxyapatite (HAp) for Biomedical Applications

Hydroxyapatite (HAp) for Biomedical Applications PDF Author: Michael Mucalo
Publisher: Elsevier
ISBN: 178242041X
Category : Medical
Languages : en
Pages : 402

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Book Description
Hydroxyapatite in the form of hydroxycarbonate apatite is the principal mineral component of bone tissue in mammals. In Bioceramics, it is classed as a bioactive material, which means bone tissue grows directly on it when placed in apposition without intervening fibrous tissue. Hydroxyapatite is hence commonly used as bone grafts, fillers and as coatings for metal implants. This important book provides an overview of the most recent research and developments involving hydroxyapatite as a key material in medicine and its application. - Reviews the important properties of hydroxyapatite as a biomaterial - Considers a range of specific forms of the material and their advantages - Reviews a range of specific medical applications for this important material