Isotope Effects

Isotope Effects PDF Author: Max Wolfsberg
Publisher: Springer Science & Business Media
ISBN: 9048122651
Category : Science
Languages : en
Pages : 477

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Book Description
As the title suggests, Isotope Effects in the Chemical, Geological and Bio Sciences deals with differences in the properties of isotopically substituted molecules, such as differences in the chemical and physical properties of water and the heavy waters. Since the various fields in which isotope effects are applied do not only share fundamental principles but also experimental techniques, this book includes a discussion of experimental apparatus and experimental techniques. Isotope Effects in the Chemical, Geological and Bio Sciences is an educational monograph addressed to graduate students and others undertaking isotope effect research. The fundamental principles needed to understand isotope effects are presented in appropriate detail. While it is true that these principles are more familiar to students of physical chemistry and some background in physical chemistry is recommended, the text provides enough detail to make the book an asset to students in organic and biochemistry, and geochemistry.

Enzyme Mechanism from Isotope Effects

Enzyme Mechanism from Isotope Effects PDF Author: Paul F. Cook
Publisher: CRC Press
ISBN: 9780849353123
Category : Medical
Languages : en
Pages : 656

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Book Description
Isotope effects have become one of the most powerful tools available to the enzymologist for probing enzymic mechanisms. Enzyme Mechanism from Isotope Effects presents the basic theory underlying isotope effects, including the latest findings on proton tunneling and coupled atomic notions. Specific theoretical applications are emphasized in regard to the types of information that can be obtained using isotope effects. The book also examines recent theoretical treatments of the product dependence of deuterium isotope effects, multiple isotope effects and isotope effects on intermediate partitioning. Other topics include a complete discussion of methods for measuring isotope effects, including a detailed description of the use of the isotope ratio mass spectrometer to obtain isotope effects, and a review of the literature regarding mechanistic information obtained from isotope effects for individual classes of enzyme-catalyzed reactions. Enzyme Mechanism from Isotope Effects is an excellent reference source for investigators using isotope effects in their research. The book is also valuable for reference libraries and instructors teaching courses in enzyme mechanism.

Isotope Effects In Chemistry and Biology

Isotope Effects In Chemistry and Biology PDF Author: Amnon Kohen
Publisher: CRC Press
ISBN: 1420028022
Category : Medical
Languages : en
Pages : 1092

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Book Description
The field of isotope effects has expanded exponentially in the last decade, and researchers are finding isotopes increasingly useful in their studies. Bringing literature on the subject up to date, Isotope Effects in Chemistry and Biology covers current principles, methods, and a broad range of applications of isotope effects in the physical, biolo

Heavy-atom Kinetic Isotope Effects

Heavy-atom Kinetic Isotope Effects PDF Author: Marvin J. Stern
Publisher:
ISBN:
Category : Chemical kinetics
Languages : en
Pages : 44

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Book Description


Proton-Transfer Reactions

Proton-Transfer Reactions PDF Author: E. F. Caldin
Publisher: Springer
ISBN: 1489930132
Category : Science
Languages : en
Pages : 446

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Book Description


Measurement and Analysis of Kinetic Isotope Effects

Measurement and Analysis of Kinetic Isotope Effects PDF Author:
Publisher: Academic Press
ISBN: 0128122749
Category : Medical
Languages : en
Pages : 634

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Book Description
Experimental Analysis of Enzyme Mechanism Using Isotope Effects, Volume 596, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this comprehensive update include Measurement of enzyme binding isotope effects, Chemical ligation and isotope labeling to locate dynamic effects, Measurement of heavy enzyme isotope effects, Extracting kinetic isotope effects from a global analysis of reaction progress curves, KIE of metabolic flux and enzymes, Solvent and Primary KIE on Flavin Enzymes, and The Rapid Determination of Primary Deuterium Isotope Effects on Enzyme-Catalyzed Proton Transfer at Carbon in 50/50 HOH/DOD. Readers who are interested in applying or understanding this research will find useful methods currently used for measuring isotope effects on solution and enzyme reactions. Written by pioneers of modern isotope effect research Is the only collection of modern kinetic isotope effect methods currently available

Magnetic Isotope Effect in Radical Reactions

Magnetic Isotope Effect in Radical Reactions PDF Author: Kev M. Salikhov
Publisher: Springer Science & Business Media
ISBN: 9783211827840
Category : Science
Languages : en
Pages : 162

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Book Description
In the last two decades it was demonstrated that, in addition to masses and charges, magnetic moments of nuclei are able to influence remarkably chemical reactions. This book presents the physical background (both theoretical and experimental) of the magnetic isotope effects in radical reactions in solutions. Special attention has been paid to the quantitative interpretation of the available experimental data. This book will be useful for physicists, chemists and biologists employing the isotope effect in their investigations as well as for those involved in isotope separation and isotope enrichment projects. Additionally, the magnetic isotope effect appears to be important in geochemistry and cosmochemistry. The book can be recommended for postgraduates and senior undergraduate students.

Isotope Effects in Chemical Reactions

Isotope Effects in Chemical Reactions PDF Author: Clair J. Collins
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 456

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Book Description


Separation of Isotopes of Biogenic Elements in Two-phase Systems

Separation of Isotopes of Biogenic Elements in Two-phase Systems PDF Author: Boris Mikhailovich Andreev
Publisher: Elsevier
ISBN: 0080468098
Category : Science
Languages : en
Pages : 317

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Book Description
Separation of Isotopes of Biogenic Elements provides a detailed overview of this area of research covering all aspects from the value of isotope effects to their practical use (equilibrium single-stage isotope effect - kinetics and mass transfer – multiplication of the single-stage isotope separation factor - technological peculiarity of processes) with the purpose of extraction from the natural mixture of the enriched and highly concentrated isotopes. In contrast to traditional books on the theory of isotope separation, the theoretical part of the book describes separation in two-phase processes in counter-flow columns. The experimental part of the book presents systematic analysis of specialists in the field of isotope separation in counter-flow columns. This book will be of interest to scientists, engineers and technical workers engaged in isotope separation processes and isotope application in nuclear physics, medicine, agro-chemistry, biology and other areas. This book may also be used in teaching theory and practical aspects in courses on physical chemistry and Isotope separation of light elements by physicochemical methods.* summarises current state of isotope research, especially biogenic elements* covering all aspects from the value of isotope effects to their practical use* of interest to scientists, engineers and technical workers engaged in isotope separation processes and isotope application

Handbook of Nuclear Chemistry

Handbook of Nuclear Chemistry PDF Author: Attila Vértes
Publisher: Springer Science & Business Media
ISBN: 144190719X
Category : Science
Languages : en
Pages : 3762

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Book Description
This revised and extended 6 volume handbook set is the most comprehensive and voluminous reference work of its kind in the field of nuclear chemistry. The Handbook set covers all of the chemical aspects of nuclear science starting from the physical basics and including such diverse areas as the chemistry of transactinides and exotic atoms as well as radioactive waste management and radiopharmaceutical chemistry relevant to nuclear medicine. The nuclear methods of the investigation of chemical structure also receive ample space and attention. The international team of authors consists of scores of world-renowned experts - nuclear chemists, radiopharmaceutical chemists and physicists - from Europe, USA, and Asia. The Handbook set is an invaluable reference for nuclear scientists, biologists, chemists, physicists, physicians practicing nuclear medicine, graduate students and teachers - virtually all who are involved in the chemical and radiopharmaceutical aspects of nuclear science. The Handbook set also provides further reading via the rich selection of references.