Cytochrome P450

Cytochrome P450 PDF Author: Paul R. Ortiz de Montellano
Publisher: Springer Science & Business Media
ISBN: 0387274472
Category : Medical
Languages : en
Pages : 702

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Book Description
Cytochrome P450: Structure, Mechanism, and Biochemistry, third edition is a revision of a review that summarizes the current state of research in the field of drug metabolism. The emphasis is on structure, mechanism, biochemistry, and regulation. Coverage is interdisciplinary, ranging from bioinorganic chemistry of cytochrome P450 to its relevance in human medicine. Each chapter provides an in-depth review of a given topic, but concentrates on advances of the last 10 years.

Cytochrome P450

Cytochrome P450 PDF Author: Paul R. Ortiz de Montellano
Publisher: Springer Science & Business Media
ISBN: 0387274472
Category : Medical
Languages : en
Pages : 702

Get Book Here

Book Description
Cytochrome P450: Structure, Mechanism, and Biochemistry, third edition is a revision of a review that summarizes the current state of research in the field of drug metabolism. The emphasis is on structure, mechanism, biochemistry, and regulation. Coverage is interdisciplinary, ranging from bioinorganic chemistry of cytochrome P450 to its relevance in human medicine. Each chapter provides an in-depth review of a given topic, but concentrates on advances of the last 10 years.

Iron-oxo Complexes

Iron-oxo Complexes PDF Author: Cheryl A. Christmas
Publisher:
ISBN:
Category :
Languages : en
Pages : 512

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Book Description


Alkane Functionalization

Alkane Functionalization PDF Author: Armando J. L. Pombeiro
Publisher: John Wiley & Sons
ISBN: 111937880X
Category : Science
Languages : en
Pages : 680

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Book Description
Presents state-of-the-art information concerning the syntheses of valuable functionalized organic compounds from alkanes, with a focus on simple, mild, and green catalytic processes Alkane Functionalization offers a comprehensive review of the state-of-the-art of catalytic functionalization of alkanes under mild and green conditions. Written by a team of leading experts on the topic, the book examines the latest research developments in the synthesis of valuable functionalized organic compounds from alkanes. The authors describe the various modes of interaction of alkanes with metal centres and examine theoxidative alkane functionalization upon C-O bond formation. They address the many types of mechanisms, discuss typical catalytic systems and highlight the strategies inspired by biological catalytic systems. The book also describes alkane functionalization upon C-heteroatom bond formation as well as oxidative and non-oxidative approaches. In addition, the book explores non-transition metal catalysts and metal-free catalytic systems and presents selected types of functionalization of sp3 C-H bonds pertaining to substrates other than alkanes. This important resource: Presents a guide to the most recent advances concerning the syntheses of valuable functionalized organic compounds from alkanes Contains information from leading experts on the topic Offers information on the catalytic functionalization of alkanes that allows for improved simplicity and sustainability compared to current multi-stage industrial processes Explores the challenges inherent with the application of alkanes as starting materials for syntheses of added value functionalized organic compounds Written for academic researchers and industrial scientists working in the fields of coordination chemistry, organometallic chemistry, catalysis, organic synthesis and green chemistry, Alkane Functionalization is an important resource for accessing the most up-to-date information available in the field of catalytic functionalization of alkanes.

Nanozymes: From Rational Design to Biomedical Applications

Nanozymes: From Rational Design to Biomedical Applications PDF Author: Kelong Fan
Publisher: Frontiers Media SA
ISBN: 2889668215
Category : Science
Languages : en
Pages : 151

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Book Description


Iron Catalysis

Iron Catalysis PDF Author: Bernd Plietker
Publisher: Springer Science & Business Media
ISBN: 3642146694
Category : Science
Languages : en
Pages : 227

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Book Description
Juan I. Padrón and Víctor S. Martín: Catalysis by means of Fe-based Lewis acids; Hiroshi Nakazawa*, Masumi Itazaki: Fe–H Complexes in Catalysis; Kristin Schröder, Kathrin Junge, Bianca Bitterlich, and Matthias Beller: Fe-catalyzed Oxidation Reactions of Olefins, Alkanes and Alcohols: Involvement of Oxo- and Peroxo Complexes; Chi-Ming Che, Cong-Ying Zhou, Ella Lai-Ming Wong: Catalysis by Fe=X Complexes (X=NR, CR2); René Peters, Daniel F. Fischer and Sascha Jautze: Ferrocene and Half Sandwich Complexes as Catalysts with Iron Participation; Markus Jegelka, Bernd Plietker: Catalysis by Means of Complex Ferrates.

Polynuclear Iron(III) Oxo Complexes as Models for the Active Centers of Selected Iron Containing Proteins

Polynuclear Iron(III) Oxo Complexes as Models for the Active Centers of Selected Iron Containing Proteins PDF Author: Sergiu M. Gorun
Publisher:
ISBN:
Category :
Languages : en
Pages : 636

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Book Description


Spin States in Biochemistry and Inorganic Chemistry

Spin States in Biochemistry and Inorganic Chemistry PDF Author: Marcel Swart
Publisher: John Wiley & Sons
ISBN: 1118898303
Category : Science
Languages : en
Pages : 472

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Book Description
It has long been recognized that metal spin states play a central role in the reactivity of important biomolecules, in industrial catalysis and in spin crossover compounds. As the fields of inorganic chemistry and catalysis move towards the use of cheap, non-toxic first row transition metals, it is essential to understand the important role of spin states in influencing molecular structure, bonding and reactivity. Spin States in Biochemistry and Inorganic Chemistry provides a complete picture on the importance of spin states for reactivity in biochemistry and inorganic chemistry, presenting both theoretical and experimental perspectives. The successes and pitfalls of theoretical methods such as DFT, ligand-field theory and coupled cluster theory are discussed, and these methods are applied in studies throughout the book. Important spectroscopic techniques to determine spin states in transition metal complexes and proteins are explained, and the use of NMR for the analysis of spin densities is described. Topics covered include: DFT and ab initio wavefunction approaches to spin states Experimental techniques for determining spin states Molecular discovery in spin crossover Multiple spin state scenarios in organometallic reactivity and gas phase reactions Transition-metal complexes involving redox non-innocent ligands Polynuclear iron sulfur clusters Molecular magnetism NMR analysis of spin densities This book is a valuable reference for researchers working in bioinorganic and inorganic chemistry, computational chemistry, organometallic chemistry, catalysis, spin-crossover materials, materials science, biophysics and pharmaceutical chemistry.

Advances in Catalytic Activation of Dioxygen by Metal Complexes

Advances in Catalytic Activation of Dioxygen by Metal Complexes PDF Author: László I. Simándi
Publisher: Springer Science & Business Media
ISBN: 0306478161
Category : Science
Languages : en
Pages : 349

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Book Description
The subject of dioxygen activation and homogeneous catalytic oxidation by metal complexes has been in the focus of attention over the last 20 years. The widespread interest is illustrated by its recurring presence among the sessions and subject areas of important international conferences on various aspects of bioinorganic and coordination chemistry as well as catalysis. The most prominent examples are ICCC, ICBIC, EUROBIC, ISHC, and of course the ADHOC series of meetings focusing on the subject itself. Similarly, the number of original and review papers devoted to various aspects of dioxygen activation are on the rise. This trend is due obviously to the relevance of catalytic oxidation to biological processes such as dioxygen transport, and the action of oxygenase and oxidase enzymes related to metabolism. The structural and functional modeling of metalloenzymes, particularly of those containing iron and copper, by means of low-molecular complexes of iron, copper, ruthenium, cobalt, manganese, etc., have provided a wealth of indirect information helping to understand how the active centers of metalloenzymes may operate. The knowledge gained from the study of metalloenzyme models is also applicable in the design of transition metal complexes as catalytsts for specific reactions. This approach has come to be known as biomimetic or bioinspired catalysis and continues to be a fruitful and expanding area of research.

Iron-containing Enzymes

Iron-containing Enzymes PDF Author: Sam P. De Visser
Publisher: Royal Society of Chemistry
ISBN: 1849731810
Category : Science
Languages : en
Pages : 463

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Book Description
Mononuclear iron containing enzymes are important intermediates in bioprocesses and have potential in the industrial biosynthesis of specific products. This book features topical review chapters by leaders in this field and its various sub-disciplines.

Biomimetic Oxidations Catalyzed By Transition Metal Complexes

Biomimetic Oxidations Catalyzed By Transition Metal Complexes PDF Author: Bernard Meunier
Publisher: World Scientific
ISBN: 1783262389
Category : Science
Languages : en
Pages : 697

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Book Description
Since the classic work Metal-Catalyzed Oxidations of Organic Compounds (edited by R A Sheldon and J K Kochi, 1991), no book has been devoted to advances in the field of biomimetic oxidations, which was created nearly 18 years ago. This expanding research field is covered in this volume. All the different aspects of the modeling of oxidations catalyzed by metalloenzymes are dealt with.This invaluable book will be useful to postgraduates as well as researchers in academia and industry, and will also benefit second year university students.