Iodine and the Brain

Iodine and the Brain PDF Author: G. Robert Delong
Publisher: Springer Science & Business Media
ISBN: 1461307651
Category : Medical
Languages : en
Pages : 376

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Book Description
This volume contains the proceedings of a conference held at the National Institutes of Health in Bethesda on March 21-23. 1988. jointly sponsored by the International Council for Control of Iodine Deficiency Disorders (ICCIDD) and the Fogarty International Center of the National Institutes of Health. Several themes converged to make this meeting timely. The first is an increasing awareness of iodine deficiency disorders as a world-wide problem of public health and a preventable cause of mental deficiency. and as a subject of scientific effort. Increased interest in these problems owes a great deal to accessibility to remote and under developed areas of the world where iodine deficiency persists. As with any subject. greater scrutiny yields unexpected complexity and interest. It is true that provision of iodine. typically as iodized salt, is the necessary and sufficient preventative for iodine deficiency disorders. without including endemic cretinism. This provision is a governmental, economic and social problem. Apart from this, however, the scientific and medical problem of iodine deficiency and its effect on brain development and function is one of great interest and importance for developmental neurology and psychology. Even though the specific preventative agent is known, we do not totally understand the neurobiological questions raised.

Iodine and the Brain

Iodine and the Brain PDF Author: G. Robert Delong
Publisher: Springer Science & Business Media
ISBN: 1461307651
Category : Medical
Languages : en
Pages : 376

Get Book Here

Book Description
This volume contains the proceedings of a conference held at the National Institutes of Health in Bethesda on March 21-23. 1988. jointly sponsored by the International Council for Control of Iodine Deficiency Disorders (ICCIDD) and the Fogarty International Center of the National Institutes of Health. Several themes converged to make this meeting timely. The first is an increasing awareness of iodine deficiency disorders as a world-wide problem of public health and a preventable cause of mental deficiency. and as a subject of scientific effort. Increased interest in these problems owes a great deal to accessibility to remote and under developed areas of the world where iodine deficiency persists. As with any subject. greater scrutiny yields unexpected complexity and interest. It is true that provision of iodine. typically as iodized salt, is the necessary and sufficient preventative for iodine deficiency disorders. without including endemic cretinism. This provision is a governmental, economic and social problem. Apart from this, however, the scientific and medical problem of iodine deficiency and its effect on brain development and function is one of great interest and importance for developmental neurology and psychology. Even though the specific preventative agent is known, we do not totally understand the neurobiological questions raised.

Endemic Cretinism

Endemic Cretinism PDF Author: John Dennison
Publisher: Springer Science & Business Media
ISBN: 1461402816
Category : Medical
Languages : en
Pages : 225

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Book Description
Responding to a renewed interest in the growing problem of iodine deficiency worldwide, Drs. Charles Oxnard and Peter Obendorf, along with experienced translator and anatomist John Dennison, take a fresh look at the classic text, Der endemische Kretinismus, published in 1936 by Springer. Translated here for the first time into English, this landmark text will be a welcome resource for researchers confronting the problem of iodine deficiency. Oxnard and Obendorf point out that there is very little detailed knowledge or numerical data on cretinism available in the English-speaking world. In addition, highly-renowned Professor Basil S. Hetzel, recently-retired World Health Organization Chairman of the International Council for Control of Iodine Deficiency Disorders, published in 2009 with Dr Chen Zu-pei on the resurgence of iodine deficiency in China. Indeed, throughout the entire developing world there may be as many as two billion people at risk to iodine deficiency; perhaps three quarters of a billion have goiter, and ten million may be cretins. Even in developed countries, iodine deficiency is re-emerging (as in New South Wales in 19% of children) with the result of significantly reduced numbers of gifted children (though this is not cretinism per se). Certain to be of significant interest to a wide range of researchers, health providers and professionals, including government health administrators, this English translation of Endemic Cretinism is a major contribution to the literature.

Comprehensive Handbook of Iodine

Comprehensive Handbook of Iodine PDF Author: Victor R Preedy
Publisher: Academic Press
ISBN: 0080920861
Category : Technology & Engineering
Languages : en
Pages : 1335

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Book Description
Over two billion people worldwide are at risk for the spectrum of disorders known as "The Iodine Deficiency Disorders." 1-10% will suffer cretinism; 5-30% will have some sort of brain damage or neurological impairment and 30-70% will be hypothyroid. The causes of iodine deficiencies can be considered from both simplistic and more complex perspectives: From the leaching of iodine from soil resulting in crops with low iodine content to malnutrition resulting in impaired iodine absorption. Poor dietary diversification and impoverished socio-economic development can also lead to iodine deficiencies. Although it is possible to diagnose and treat deficiencies, there is still an ongoing dialogue regarding the detailed molecular pathology of iodine homeostatis, how hypothyroidism impacts the body tissues, and efficient diagnosis and treatment of the Iodine Deficiency Disorders. This Handbook provides a resource of information on the various pathways and processes based on different countries or diseases. Because there is a constant flow of new information on iodine and related disorders, the goal of this Handbook is to provide a base of scientific information upon which additional knowledge can be applied. - Provides important information on one of the most common micro-nutrient deficiencies in the world, the most important "single nutrient-multiple consequences" paradigm today - Includes information on iodine-related diseases, including those that are common, preventable and treatable - Provides insight from a broad perspective of viewpoints -- from subcellular transports to economic impact

Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc

Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 9780309072793
Category : Medical
Languages : en
Pages : 804

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Book Description
This volume is the newest release in the authoritative series issued by the National Academy of Sciences on dietary reference intakes (DRIs). This series provides recommended intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for individuals based on age and gender. In addition, a new reference intake, the Tolerable Upper Intake Level (UL), has also been established to assist an individual in knowing how much is "too much" of a nutrient. Based on the Institute of Medicine's review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health. The book also: Reviews selected components of food that may influence the bioavailability of these compounds. Develops estimates of dietary intake of these compounds that are compatible with good nutrition throughout the life span and that may decrease risk of chronic disease where data indicate they play a role. Determines Tolerable Upper Intake levels for each nutrient reviewed where adequate scientific data are available in specific population subgroups. Identifies research needed to improve knowledge of the role of these micronutrients in human health. This book will be important to professionals in nutrition research and education.

Iodine Deficiency in Europe

Iodine Deficiency in Europe PDF Author: F. Delange
Publisher: Springer Science & Business Media
ISBN: 1489912452
Category : Medical
Languages : en
Pages : 467

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Book Description
The disorders induced by iodine deficiency affect at least one billion people. Because ofits effects on brain development, iodinedeficiency is the single most preventable cause of mental retardation in the world. Therefore, the United Nations and the Heads of State of almost all the world's countries represented at the Summit for Children in 1990 adopted resolutions to eradicate the disorders induced by iodine deficiency (IDD) by the year 2000. For geological and socio-economic reasons, most of the populations affected by iodine deficiency disorders live in isolated and usually mountainous areas, in pre industrialized parts ofthe world. The problem of iodine deficiency in Europe has been greatly underestimated in the last decades. After the remarkable studies on the effects of iodine deficiency and their prevention and correction in Switzerland, IDD was generally considered no longer a significant public health problem in Europe. However, surveys carried out in the early 1980's under the auspices of the European Thyroid Association, clearly demonstrated the persistence of moderately or even severely affected areas. These surveys also highlighted the lack ofinformation about large parts ofEurope, especially its eastern part. It is only quite recently, following major changes in international relations and thanks to the support of UNICEF, WHO, the International Council for the Control of Iodine Deficiency Disorders and the European Thyroid Association, that more extensive surveys have been conducted in several parts of Europe hitherto almost unexplored. These surveys showed that most European countries were iodine deficient.

Fluoride in Drinking Water

Fluoride in Drinking Water PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030910128X
Category : Nature
Languages : en
Pages : 531

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Book Description
Most people associate fluoride with the practice of intentionally adding fluoride to public drinking water supplies for the prevention of tooth decay. However, fluoride can also enter public water systems from natural sources, including runoff from the weathering of fluoride-containing rocks and soils and leaching from soil into groundwater. Fluoride pollution from various industrial emissions can also contaminate water supplies. In a few areas of the United States fluoride concentrations in water are much higher than normal, mostly from natural sources. Fluoride is one of the drinking water contaminants regulated by the U.S. Environmental Protection Agency (EPA) because it can occur at these toxic levels. In 1986, the EPA established a maximum allowable concentration for fluoride in drinking water of 4 milligrams per liter, a guideline designed to prevent the public from being exposed to harmful levels of fluoride. Fluoride in Drinking Water reviews research on various health effects from exposure to fluoride, including studies conducted in the last 10 years.

Thyroid Hormone Metabolism

Thyroid Hormone Metabolism PDF Author: Georg Hennemann
Publisher: Marcel Dekker
ISBN:
Category : Medical
Languages : en
Pages : 656

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Book Description


The Iodine Crisis

The Iodine Crisis PDF Author: Lynne Farrow
Publisher: DEVON Press
ISBN: 9780986032004
Category : Alternative medicine
Languages : en
Pages : 0

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Book Description
The author presents information, case studies and patients' experiences researching and using iodine to counteract bromine exposure as well as diseases such as breast disease and cancer, prostate cancer, thyroid diseases, weight gain and brain fog.

Human Brain Evolution

Human Brain Evolution PDF Author: Stephen Cunnane
Publisher: John Wiley & Sons
ISBN: 9780470609873
Category : Social Science
Languages : en
Pages : 232

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Book Description
The evolution of the human brain and cognitive ability is one of the central themes of physical/biological anthropology. This book discusses the emergence of human cognition at a conceptual level, describing it as a process of long adaptive stasis interrupted by short periods of cognitive advance. These advances were not linear and directed, but were acquired indirectly as part of changing human behaviors, in other words through the process of exaptation (acquisition of a function for which it was not originally selected). Based on studies of the modem human brain, certain prerequisites were needed for the development of the early brain and associated cognitive advances. This book documents the energy and nutrient constraints of the modern brain, highlighting the significant role of long-chain polyunsaturated fatty acids (LC-PUFA) in brain development and maintenance. Crawford provides further emphasis for the role of essential fatty acids, in particular DHA, in brain development, by discussing the evolution of the eye and neural systems. This is an ideal book for Graduate students, post docs, research scientists in Physical/Biological Anthropology, Human Biology, Archaeology, Nutrition, Cognitive Science, Neurosciences. It is also an excellent selection for a grad student discussion seminar.

Breast Cancer and Iodine

Breast Cancer and Iodine PDF Author: David M. Derry
Publisher: Trafford on Demand Pub
ISBN: 1552128849
Category : Health & Fitness
Languages : en
Pages : 109

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Book Description
I have taken my personal experience in practice along with the details of treatment of patient together with published literature and proposed a testable theory of breast cancer. The lack of a theory of cancer and especially breast cancer has made treatment difficult and empirical. The book is divided into four parts. The first part discusses iodine. From published facts, we can arrive at a proposal that iodine could be the first phase of a two phase cancer defence system. It appears that iodine in the extra-cellular fluid outside of the cells is the main surveillance system for abnormal cells. Iodine also triggers the natural death of normal cells in the body. There are many cells types in the body undergoing a natural death. For example some of the cells in the stomach have lives of only 2-3 days. The name of this process is apoptosis. Carefully documented descriptions of the cancer process at different places in the body reveals most cancers have similar stages through which it passes. The cancers are not really cancer until the cells start to move by invasion through the nearby connective tissue. Cells develop abnormalities for a variety of reasons and can continue to become abnormal all the way up through atypical cells and to carcinoma in situ. Carcinoma in situ is the dividing line between the two phases of cancer development. Iodine in correct doses will reverse all of the changes up to and including the carcinoma in situ. The thyroid hormone controls connective tissue function. So connective tissue around organs forms a structural biological barrier to the spread of cancer. Cancer spread to distant organs only develops in the connective tissue of those organs. Therefore, if the connective tissue defence is not strong then the cancerous cell from a distant site can land there and grow. If however the thyroid hormone level in the connective tissue is high enough then the connective tissue will perform its normal defence duties and not allow the cancer cell to enter it and develop. Using these principles, fibrocystic disease and breast cancer become more understandable. Supplemental iodine in the correct doses will remove all lesions from carcinoma in situ back to just an abnormal cell by triggering death of these cells by apoptosis. Spread of cancer cells in the connective tissue can be arrested by adequate treatment with thyroid hormone to strengthen the connective tissue barrier. My experience with patients using this approach so far has been successful. The principles are that there are two phases to cancer one controlled by iodine and the other by thyroid hormone. Thus the book deals with the prevention and survival of breast cancer.