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Author: Alexander Christopher Thompson
Publisher: Swinburne University of Technology
ISBN:
Category : Technology & Engineering
Languages : en
Pages : 241
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Book Description
The cochlear implant is a successful bionic device, restoring hearing to hundreds of thousands of patients worldwide. Despite its success, present devices are limited by the electrical interface with neurons. This thesis studied the ability of infrared light to stimulate the nerves of the cochlea. Experimental work was unable to replicate previously published results and suggests that those reports may be an acoustic artefact. However, modelling of light transport in tissue confirmed the ability of light to improve spatial localisation of stimulation, showing the potential of other optical stimulation techniques
Author: Alexander Christopher Thompson
Publisher: Swinburne University of Technology
ISBN:
Category : Technology & Engineering
Languages : en
Pages : 241
Get Book Here
Book Description
The cochlear implant is a successful bionic device, restoring hearing to hundreds of thousands of patients worldwide. Despite its success, present devices are limited by the electrical interface with neurons. This thesis studied the ability of infrared light to stimulate the nerves of the cochlea. Experimental work was unable to replicate previously published results and suggests that those reports may be an acoustic artefact. However, modelling of light transport in tissue confirmed the ability of light to improve spatial localisation of stimulation, showing the potential of other optical stimulation techniques
Author:
Publisher: ScholarlyEditions
ISBN: 1490108718
Category : Technology & Engineering
Languages : en
Pages : 1153
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Book Description
Issues in Biomedical Engineering Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Reproductive Biomedicine. The editors have built Issues in Biomedical Engineering Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Reproductive Biomedicine in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biomedical Engineering Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Kadharbatcha S. Saleem
Publisher: Academic Press
ISBN: 0123850878
Category : Medical
Languages : en
Pages : 402
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Book Description
A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates, Second Edition maps the detailed architectonic subdivisions of the cortical and subcortical areas in the macaque monkey brain using high-resolution magnetic resonance (MR) images and the corresponding histology sections in the same animal. This edition of the atlas is unlike anything else available as it includes the detailed cyto- and chemoarchitectonic delineations of the brain areas in all three planes of sections (horizontal, coronal, and sagittal) that are derived from the same animal. This is a significant progress because in functional imaging studies, such as fMRI, both the horizontal and sagittal planes of sections are often the preferred planes given that multiple functionally active regions can be visualized simultaneously in a single horizontal or sagittal section. This combined MRI and histology atlas is designed to provide an easy-to-use reference for anatomical and physiological studies in macaque monkeys, and in functional-imaging studies in human and non-human primates using fMRI and PET. The first rhesus monkey brain atlas with horizontal, coronal, and sagittal planes of sections, derived from the same animal Shows the first detailed delineations of the cortical and subcortical areas in horizontal, coronal, and sagittal plane of sections in the same animal using different staining methods Horizonal series illustrates the dorsoventral extent of the left hemisphere in 47 horizontal MRI and photomicrographic sections matched with 47 detailed diagrams (Chapter 3) Coronal series presents the full rostrocaudal extent of the right hemisphere in 76 coronal MRI and photomicrographic sections, with 76 corresponding drawings (Chapter 4) Sagittal series shows the complete mediolateral extent of the left hemisphere in 30 sagittal MRI sections, with 30 corresponding drawings (Chapter 5). The sagittal series also illustrates the location of different fiber tracts in the white matter Individual variability - provides selected cortical and subcortical areas in three-dimensional MRI (horizontal, coronal, and sagittal MRI planes). For comparison, it also provides similar areas in coronal MRI section in six other monkeys. (Chapter 6) Vasculature - indicates the corresponding location of all major blood vessels in horizontal, coronal, and sagittal series of sections Provides updated information on the cortical and subcortical areas, such as architectonic areas and nomenclature, with references, in chapter 2 Provides the sterotaxic grid derived from the in-vivo MR image
Author: Colleen G. Le Prell
Publisher: Springer
ISBN: 3319408488
Category : Medical
Languages : en
Pages : 275
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Book Description
Translational Research is the interface between basic science and human clinical application, including the entire process from animal studies to human clinical trials (phases I, II, and III). Translational Research moves promising basic science results from the laboratory to bedside application. Yet, this transition is often the least-defined, least-understood part of the research process. Most scientific training programs provide little or no systematic introduction to the issues, challenges, and obstacles that prevent effective research translation, even though these are the key steps that enable high-impact basic science to ultimately result in significant clinical advances that improve patient outcome. This volume will provide an overview of key issues in translation of research from “bedside to bench to bedside”, not only from the perspective of the key funding agencies, but also from the scientists and clinicians who are currently involved in the translational research process. It will attempt to offer insight into real-world experience with intellectual property and technology transfer activities that can help move auditory technologies ahead, as scientists and clinicians typically have little or no formal training in these areas. Translational Research in Audiology and the Hearing Sciences will be aimed at graduate students and postdoctoral investigators, as well as professionals and academics. It is intended to function as a high-profile and up-to-date reference work on Translational Research in the auditory sciences, emphasizing research programs in the traditional areas including drugs and devices, as well as less traditional, still emerging, areas such as sensorineural hearing loss, auditory processing disorder, cochlear implants and hearing aids, and tinnitus therapies.
Author: Krishnarao Appasani
Publisher: Cambridge University Press
ISBN: 1108146090
Category : Medical
Languages : en
Pages : 537
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Book Description
Discovered little more than a decade ago, optogenetics - a revolutionary technique combining genetic and optical methods to observe and control the function of neurons - is now a widely used research tool. Optogenetics-driven research has led to insights into Parkinson's disease and other neurological and psychiatric disorders. With contributions from leaders and innovators from both academia and industry, this volume explores the discovery and application of optogenetics, from the basic science to its potential clinical use. Chapters cover a range of optogenetics applications, including for brain circuits, plasticity, memory, learning, sleep, vision and neurodegenerative and neuropsychiatric diseases. Providing authoritative coverage of the huge potential that optogenetics research carries, this is an ideal resource for researchers and graduate students, as well as for those working in the biotechnology and pharmaceutical industries and in a clinical setting.
Author: Alain Dabdoub
Publisher: Springer
ISBN: 1493930311
Category : Medical
Languages : en
Pages : 300
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Book Description
This volume details the essential role of the spiral ganglion neurons. The volume elucidates and characterizes their development, their environment, their electrophysiological characteristics, their connectivity to their targets in the inner ear and the brain, and discusses the potential for their regeneration. A comprehensive review about the spiral ganglion neurons is important for researchers not only in the inner ear field but also in development, neuroscience, biophysics as well as neural networks researchers. The chapters are authored by leading researchers in the field.
Author: Brian J.-F. Wong
Publisher: Springer
ISBN: 1493917587
Category : Medical
Languages : en
Pages : 654
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Book Description
Biomedical Optics in Otorhinolaryngology: Head and Neck Surgery gives an overview of current technology in biomedical optics relevant to the field of Otorhinolaryngology and head and neck surgery. It provides a comprehensive source of knowledge for researchers and active clinicians seeking information on the principles and practical use of novel diagnostic and therapeutic technology. While most books focus exclusively on laser surgery, which has been largely unchanged for the past 15 years, optical diagnostics and head and neck PDT (photodynamic therapy) are usually entirely overlooked. This book contains a basic introduction into the physics of light and its propagation, lasers and low-coherent light sources, and photon-tissue interaction in relation to therapeutic and diagnostic use. The principles of various imaging techniques are also discussed ( i.e. optical coherence tomography in its variations), as well as the principles and practice of lasers for surgical use on the therapeutic side.
Author: Fan-Gang Zeng
Publisher: Springer Science & Business Media
ISBN: 1441994343
Category : Medical
Languages : en
Pages : 397
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Book Description
Cochlear implants are currently the standard treatment for profound sensorineural hearing loss. In the last decade, advances in auditory science and technology have not only greatly expanded the utility of electric stimulation to other parts of the auditory nervous system in addition to the cochlea, but have also demonstrated drastic changes in the brain in responses to electric stimulation, including changes in language development and music perception. Volume 20 of SHAR focused on basic science and technology underlying the cochlear implant. However, due to the newness of the ideas and technology, the volume did not cover any emerging applications such as bilateral cochlear implants, combined acoustic-electric stimulation, and other types of auditory prostheses, nor did it review brain plasticity in responses to electric stimulation and its perceptual and language consequences. This proposed volume takes off from Volume 20, and expands the examination of implants into new and highly exciting areas. This edited book starts with an overview and introduction by Dr. Fan-Gang Zeng. Chapters 2-9 cover technological development and the advances in treating the full spectrum of ear disorders in the last ten years. Chapters 10-15 discuss brain responses to electric stimulation and their perceptual impact. This volume is particularly exciting because there have been quantum leap from the traditional technology discussed in Volume 20. Thus, this volume is timely and will be of real importance to the SHAR audience.
Author: Michael J. Ruckenstein
Publisher: Elsevier Health Sciences
ISBN: 0323710573
Category : Medical
Languages : en
Pages : 201
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Book Description
This issue of Otolaryngologic Clinics, guest edited by Drs. Michael Ruckenstein and James G. Naples, is devoted to Cranial Nerve Stimulation in Otolaryngology. Articles in this issue include: History of Cranial Nerurostimulation; Social and Ethical Considerations in Cranial Nerve Implants; Concepts in Neural Stimulation; Central Effects of Cranial Nerve Stimulation; Special Considerations in Patients with Cranial Nerve Implants; CN I- Olfactory Nerve Stimulator; Cochlear Nerve: Cochlear Implant; Cochlear Nerve: Auditory Brainstem Implant; Vestibular Nerve: Vestibular Implant; CN X- Vagal Nerve Stimulator; CN X- Recurrent Laryngeal Nerve Stimulator; CN XII- Hypoglossal Nerve Stimulator; and The Future of Cranial Nerve Stimulation.
Author: Ch.W. Sensen
Publisher: Springer Science & Business Media
ISBN: 3540689931
Category : Medical
Languages : en
Pages : 447
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Book Description
A picture says more than a thousand words. This is something that we all know to be true. Imaging has been important since the early days of medicine and bi- ogy, as seen in the anatomical studies of Leonardo Da Vinci or Andreas Vesalius. More than 100 years ago, the ?rst noninvasive imaging technologies, such as K- rad Roentgen’s X-ray technology,were applied to the medical ?eld—and while still crude—revolutionized medical diagnosis. Today, every patient will be exposed to some kind of advanced imaging technology such as medical resonance imaging, computed tomography or four-dimensional ultrasound during their lifetime. Many diseases, such as brain tumors, are initially diagnosed solely by imaging, and most of the surgical planning relies on the patient imagery. 4D ultrasound is available to expecting parents who wish to create unique early memories of the new baby, and it may soon be used for the morphometric diagnosis of malformations that may one day be treatable—inutero! Light and electron microscopy are unequal brethren, which have contributed to most of our knowledge about the existence and organization of cells, tissues and microorganisms. Every student of biology or medicine is introduced to the fascinating images of the microcosm. New advances have converted these im- ing technologies, which were considered by many to be antiquated, into powerful tools for research in systems biology and related ?elds.
