Introduction to Bio-Ontologies

Introduction to Bio-Ontologies PDF Author: Peter N. Robinson
Publisher: CRC Press
ISBN: 1439836663
Category : Computers
Languages : en
Pages : 514

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Book Description
Introduction to Bio-Ontologies explores the computational background of ontologies. Emphasizing computational and algorithmic issues surrounding bio-ontologies, this self-contained text helps readers understand ontological algorithms and their applications.The first part of the book defines ontology and bio-ontologies. It also explains the importan

Introduction to Bio-Ontologies

Introduction to Bio-Ontologies PDF Author: Peter N. Robinson
Publisher: CRC Press
ISBN: 1439836663
Category : Computers
Languages : en
Pages : 514

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Book Description
Introduction to Bio-Ontologies explores the computational background of ontologies. Emphasizing computational and algorithmic issues surrounding bio-ontologies, this self-contained text helps readers understand ontological algorithms and their applications.The first part of the book defines ontology and bio-ontologies. It also explains the importan

The Gene Ontology Handbook

The Gene Ontology Handbook PDF Author: Christophe Dessimoz
Publisher:
ISBN: 9781013267710
Category : Science
Languages : en
Pages : 298

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Book Description
This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Biomedical Natural Language Processing

Biomedical Natural Language Processing PDF Author: Kevin Bretonnel Cohen
Publisher: John Benjamins Publishing Company
ISBN: 9027271062
Category : Computers
Languages : en
Pages : 174

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Book Description
Biomedical Natural Language Processing is a comprehensive tour through the classic and current work in the field. It discusses all subjects from both a rule-based and a machine learning approach, and also describes each subject from the perspective of both biological science and clinical medicine. The intended audience is readers who already have a background in natural language processing, but a clear introduction makes it accessible to readers from the fields of bioinformatics and computational biology, as well. The book is suitable as a reference, as well as a text for advanced courses in biomedical natural language processing and text mining.

Knowledge-Based Bioinformatics

Knowledge-Based Bioinformatics PDF Author: Gil Alterovitz
Publisher: John Wiley & Sons
ISBN: 1119995833
Category : Medical
Languages : en
Pages : 306

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Book Description
There is an increasing need throughout the biomedical sciences for a greater understanding of knowledge-based systems and their application to genomic and proteomic research. This book discusses knowledge-based and statistical approaches, along with applications in bioinformatics and systems biology. The text emphasizes the integration of different methods for analysing and interpreting biomedical data. This, in turn, can lead to breakthrough biomolecular discoveries, with applications in personalized medicine. Key Features: Explores the fundamentals and applications of knowledge-based and statistical approaches in bioinformatics and systems biology. Helps readers to interpret genomic, proteomic, and metabolomic data in understanding complex biological molecules and their interactions. Provides useful guidance on dealing with large datasets in knowledge bases, a common issue in bioinformatics. Written by leading international experts in this field. Students, researchers, and industry professionals with a background in biomedical sciences, mathematics, statistics, or computer science will benefit from this book. It will also be useful for readers worldwide who want to master the application of bioinformatics to real-world situations and understand biological problems that motivate algorithms.

Building Ontologies with Basic Formal Ontology

Building Ontologies with Basic Formal Ontology PDF Author: Robert Arp
Publisher: MIT Press
ISBN: 026232959X
Category : Science
Languages : en
Pages : 245

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Book Description
An introduction to the field of applied ontology with examples derived particularly from biomedicine, covering theoretical components, design practices, and practical applications. In the era of “big data,” science is increasingly information driven, and the potential for computers to store, manage, and integrate massive amounts of data has given rise to such new disciplinary fields as biomedical informatics. Applied ontology offers a strategy for the organization of scientific information in computer-tractable form, drawing on concepts not only from computer and information science but also from linguistics, logic, and philosophy. This book provides an introduction to the field of applied ontology that is of particular relevance to biomedicine, covering theoretical components of ontologies, best practices for ontology design, and examples of biomedical ontologies in use. After defining an ontology as a representation of the types of entities in a given domain, the book distinguishes between different kinds of ontologies and taxonomies, and shows how applied ontology draws on more traditional ideas from metaphysics. It presents the core features of the Basic Formal Ontology (BFO), now used by over one hundred ontology projects around the world, and offers examples of domain ontologies that utilize BFO. The book also describes Web Ontology Language (OWL), a common framework for Semantic Web technologies. Throughout, the book provides concrete recommendations for the design and construction of domain ontologies.

Applied Ontology

Applied Ontology PDF Author: Katherine Munn
Publisher: Walter de Gruyter
ISBN: 3110324865
Category : Philosophy
Languages : en
Pages : 342

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Book Description
Ontology is the philosophical discipline which aims to understand how things in the world are divided into categories and how these categories are related together. This is exactly what information scientists aim for in creating structured, automated representations, called ‘ontologies,’ for managing information in fields such as science, government, industry, and healthcare. Currently, these systems are designed in a variety of different ways, so they cannot share data with one another. They are often idiosyncratically structured, accessible only to those who created them, and unable to serve as inputs for automated reasoning. This volume shows, in a non-technical way and using examples from medicine and biology, how the rigorous application of theories and insights from philosophical ontology can improve the ontologies upon which information management depends.

The Ontological Turn

The Ontological Turn PDF Author: Martin Holbraad
Publisher: Cambridge University Press
ISBN: 1107103886
Category : Philosophy
Languages : en
Pages : 355

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Book Description
This book provides the first systematic presentation of anthropology's 'ontological turn', placing it in the landscape of contemporary social theory.

An Introduction to Ontology Engineering

An Introduction to Ontology Engineering PDF Author: C. Maria Keet
Publisher:
ISBN: 9781848902954
Category : Computer software
Languages : en
Pages : 344

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Book Description
An Introduction to Ontology Engineering introduces the student to a comprehensive overview of ontology engineering, and offers hands-on experience that illustrate the theory. The topics covered include: logic foundations for ontologies with languages and automated reasoning, developing good ontologies with methods and methodologies, the top-down approach with foundational ontologies, and the bottomup approach to extract content from legacy material, and a selection of advanced topics that includes Ontology-Based Data Access, the interaction between ontologies and natural languages, and advanced modelling with fuzzy and temporal ontologies. Each chapter contains review questions and exercises, and descriptions of two group assignments are provided as well. The textbook is aimed at advanced undergraduate/postgraduate level in computer science and could fi t a semester course in ontology engineering or a 2-week intensive course. Domain experts and philosophers may fi nd a subset of the chapters of interest, or work through the chapters in a different order. Maria Keet is an Associate Professor with the Department of Computer Science, University of Cape Town, South Africa. She received her PhD in Computer Science in 2008 at the KRDB Research Centre, Free University of Bozen-Bolzano, Italy. Her research focus is on knowledge engineering with ontologies and Ontology, and their interaction with natural language and conceptual data modelling, which has resulted in over 100 peer-reviewed publications. She has developed and taught multiple courses on ontology engineering and related courses at various universities since 2009.

Data and Text Processing for Health and Life Sciences

Data and Text Processing for Health and Life Sciences PDF Author: Francisco M. Couto
Publisher: Springer
ISBN: 3030138453
Category : Medical
Languages : en
Pages : 107

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Book Description
This open access book is a step-by-step introduction on how shell scripting can help solve many of the data processing tasks that Health and Life specialists face everyday with minimal software dependencies. The examples presented in the book show how simple command line tools can be used and combined to retrieve data and text from web resources, to filter and mine literature, and to explore the semantics encoded in biomedical ontologies. To store data this book relies on open standard text file formats, such as TSV, CSV, XML, and OWL, that can be open by any text editor or spreadsheet application. The first two chapters, Introduction and Resources, provide a brief introduction to the shell scripting and describe popular data resources in Health and Life Sciences. The third chapter, Data Retrieval, starts by introducing a common data processing task that involves multiple data resources. Then, this chapter explains how to automate each step of that task by introducing the required commands line tools one by one. The fourth chapter, Text Processing, shows how to filter and analyze text by using simple string matching techniques and regular expressions. The last chapter, Semantic Processing, shows how XPath queries and shell scripting is able to process complex data, such as the graphs used to specify ontologies. Besides being almost immutable for more than four decades and being available in most of our personal computers, shell scripting is relatively easy to learn by Health and Life specialists as a sequence of independent commands. Comprehending them is like conducting a new laboratory protocol by testing and understanding its procedural steps and variables, and combining their intermediate results. Thus, this book is particularly relevant to Health and Life specialists or students that want to easily learn how to process data and text, and which in return may facilitate and inspire them to acquire deeper bioinformatics skills in the future.

Handbook Of Metadata, Semantics And Ontologies

Handbook Of Metadata, Semantics And Ontologies PDF Author: Miguel-angel Sicilia
Publisher: World Scientific
ISBN: 9814590355
Category : Computers
Languages : en
Pages : 579

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Book Description
Metadata research has emerged as a discipline cross-cutting many domains, focused on the provision of distributed descriptions (often called annotations) to Web resources or applications. Such associated descriptions are supposed to serve as a foundation for advanced services in many application areas, including search and location, personalization, federation of repositories and automated delivery of information. Indeed, the Semantic Web is in itself a concrete technological framework for ontology-based metadata. For example, Web-based social networking requires metadata describing people and their interrelations, and large databases with biological information use complex and detailed metadata schemas for more precise and informed search strategies.There is a wide diversity in the languages and idioms used for providing meta-descriptions, from simple structured text in metadata schemas to formal annotations using ontologies, and the technologies for storing, sharing and exploiting meta-descriptions are also diverse and evolve rapidly. In addition, there is a proliferation of schemas and standards related to metadata, resulting in a complex and moving technological landscape — hence, the need for specialized knowledge and skills in this area.The Handbook of Metadata, Semantics and Ontologies is intended as an authoritative reference for students, practitioners and researchers, serving as a roadmap for the variety of metadata schemas and ontologies available in a number of key domain areas, including culture, biology, education, healthcare, engineering and library science.