Intraoperative Radiotherapy (IORT) – A New Frontier for Personalized Medicine as Adjuvant Treatment and Treatment of Locally Recurrent Advanced Malignancy PDF Download
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Author: William Small, Jr.
Publisher: Frontiers Media SA
ISBN: 288945794X
Category :
Languages : en
Pages : 76
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Book Description
Intraoperative radiotherapy (IORT) is a treatment delivery technique with reports starting in the early 20th century. There are numerous advantages of IORT in oncology including delivery of a tumoricidal radiation dose in a single treatment, direct visualization of the treatment area of interest, decreasing dose to surrounding tissues, among others. In this series we focus on the clinical application, radiobiology and physics of IORT with an emphasis on the Intrabeam system. As medicine and health care continue to evolve the new frontier of personalized medicine must continue to rigorously evaluate and implement technologies that limit costs and provide meaningful therapeutic benefit.
Author: William Small, Jr.
Publisher: Frontiers Media SA
ISBN: 288945794X
Category :
Languages : en
Pages : 76
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Book Description
Intraoperative radiotherapy (IORT) is a treatment delivery technique with reports starting in the early 20th century. There are numerous advantages of IORT in oncology including delivery of a tumoricidal radiation dose in a single treatment, direct visualization of the treatment area of interest, decreasing dose to surrounding tissues, among others. In this series we focus on the clinical application, radiobiology and physics of IORT with an emphasis on the Intrabeam system. As medicine and health care continue to evolve the new frontier of personalized medicine must continue to rigorously evaluate and implement technologies that limit costs and provide meaningful therapeutic benefit.
Author: William Small
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author: Leonard L. Gunderson
Publisher: Springer Science & Business Media
ISBN: 161779015X
Category : Medical
Languages : en
Pages : 533
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Book Description
The rationale for using intraoperative irradiation (IORT) is based on the realization that tolerable doses of eternal beam radiation are often insufficient to achieve control of locally advanced malignancies. In these instances, the IORT component of treatment becomes the optimal conformal technique of irradiation, since dose-limiting organs or structures can either be surgically displaced or protected by placement of lead shielding. This fully revised and expanded second edition is of interest to those with intraoperative electron (IOERT) capabilities, high-dose-rate brachytherapy (HDR-IORT) capabilities, or both. Techniques, indications, and results are discussed by disease site. Each chapter is dual authored by a radiation oncologist and a surgeon, giving a balanced presentation of clinical scenarios. Issues of basic science and physics are also covered, and a notable chapter on normal tissue tolerance is included. Intraoperative Irradiation: Techniques and Results, Second Edition is a superb compilation, providing essential cutting-edge knowledge. It is a foundation for physicians as IORT develops and becomes more widely available.
Author: Jerome M. Vaeth
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805564562
Category : Medical
Languages : en
Pages : 294
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Book Description
Over the past two decades, intraoperative radiotherapy (IORT) has been used for a variety of malignant tumors and has contributed significantly to improve local tumor control. Based on the 31st San Francisco Cancer Symposium and the 6th International Intraoperative Radiation Therapy Symposium in 1996, this book presents the most recent information available on the use of IORT in cancer treatment. A brief historical overview of the development of IORT is followed by discussions of its biological, physical and technical aspects. The main part of the book is devoted to the clinical applications of IORT and the results of its use in the management of cancers of the brain, head and neck, gastrointestinal tract, breast, bone, lung, urinary tract and gynecological region, and of sarcomas. A further topic considered is the quality of life patients undergoing IORT. The findings presented indicate that IORT provides a major contribution to the control of locally advanced cancer and, in many instances, can improve long-term survival. This book is recommended reading for all clinical practitioners of oncology - surgeons, radiation oncologists and medical oncologists - as well as for radiobiologists, physicists and engineers interested in the technical development of this form of treatment.
Author: Felipe A. Calvo
Publisher: Springer Science & Business Media
ISBN: 364284183X
Category : Medical
Languages : en
Pages : 197
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Book Description
The development of the capacity to use electron beams at various energies stimulated the development of the new technology of intraoperative radiation therapy. The visual ization of the primary tumor, definition of the site to be irradiated, and knowledge of the size of tumor to be irradiated, including adequate margins for microscopic extent along with debulking of the tumor, have allowed intraoperative radiation therapy to be pur sued in a wide variety of disease processes. Not only is it possible to treat tumors that were highly resistant, but it is also possible to specifically localize the tumor with a mar gin adequate to encompass potential microscopic extensions and to choose the appro priate electron beam energy to treat the potential residual tumor and spare the adjacent normal structures. It is, furthermore, possible to treat patients with unresectable tumors. Central to this entire development is the fact that normal structures can be removed from the field of treatment. In the beginning, the emphasis was on single fractions of electron beam radiation without subsequent supplementation by external photon beam radiation therapy. How ever, more recently it has become necessary to use not only a single electron beam frac tion during the course of the operation, but to supplement it with external beam treat ment. The encouraging results obtained with intraoperative radiation therapy have led to clinical trials at a large number of institutions throughout the world.
Author: Mohammed Keshtgar
Publisher: Springer Science & Business Media
ISBN: 3642398219
Category : Medical
Languages : en
Pages : 175
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Book Description
Targeted intraoperative radiotherapy is a major advance in the management of cancer patients and has been attracting massive interest worldwide following publication of the results of an important randomized controlled trial in The Lancet. This textbook is designed to introduce this innovative technology in a comprehensive manner to clinicians dealing with cancer patients. Throughout, the emphasis is on practical aspects and the text is supported by many excellent illustrations. The editors of the book have extensive experience in targeted intraoperative radiotherapy and include co-directors of the TARGIT Academy, which runs international training courses on the technology in the United Kingdom and Germany. They have brought together multidisciplinary contributors from different centers across the world who have wide experience in the field and whose work has been recognized internationally. It is the editors’ hope that this book will succeed in ensuring that targeted intraoperative radiotherapy is used effectively worldwide.
Author: Bruce G. Haffty
Publisher: Rutgers University Press
ISBN: 0813592542
Category : Medical
Languages : en
Pages : 238
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Book Description
Precision medicine is a rapidly-evolving field in the management of cancer. The use of novel molecular or genetic signatures in local-regional management is still in its infancy. Precision Radiation Oncology demystifies this state-of-the-art research and technology. By describing current existing clinical and pathologic features, and focusing on the ability to improve outcomes in cancer using radiation therapy, this book discusses incorporating novel genomic- or biology-based biomarkers in the treatment of patients moving radiation oncology into precision/personalized medicine. Precision Radiation Oncology provides readers with an overview of the new developments of precision medicine in radiation oncology, further advancing the integration of new research findings into individualized radiation therapy and its clinical applications.
Author: Ralph R. Dobelbower, Jr.
Publisher: CRC Press
ISBN: 9780849368462
Category : Medical
Languages : en
Pages : 434
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Book Description
A comprehensive review of intraoperative radiation therapy, beginning with the rationale for innovative treatment and the radiobiology of single doses. Problems encountered in modifying a linear accelerator and a radiation therapy suite are reviewed in detail along with special problems relating to technology, nursing, anesthesiology, and various surgical subspecialties. Intraoperative radiation therapy applicators and dosimetric considerations are also reviewed. This text is a valuable reference tool for institutions planning to develop or construct intraoperative radiation therapy facilities.
Author: Carsten Nieder
Publisher: Springer
ISBN: 3319418254
Category : Medical
Languages : en
Pages : 368
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Book Description
This book, now in its second edition, provides a comprehensive overview of current re-irradiation strategies, with detailed discussion of re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance. In addition, disease specific chapters document recent clinical results and future research directions. All chapters from the first edition have been revised and updated to take account of the latest developments and research findings, including those from prospective studies. Due attention is paid to the exciting developments in the fields of proton irradiation and frameless image-guided ablative radiotherapy. The book documents fully how refined combined modality approaches and significant technical advances in radiation treatment planning and delivery have facilitated the re-irradiation of previously exposed volumes, allowing both palliative and curative approaches to be pursued at various disease sites. Professionals involved in radiation treatment planning and multimodal oncology treatment will find it to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.
Author: Dorland
Publisher: Elsevier Health Sciences
ISBN: 0323442544
Category : Medical
Languages : en
Pages : 481
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Book Description
Medical acronyms and abbreviations offer convenience, but those countless shortcuts can often be confusing. Now a part of the popular Dorland's suite of products, this reference features thousands of terms from across various medical specialties. Its alphabetical arrangement makes for quick reference, and expanded coverage of symbols ensures they are easier to find. Effective communication plays an important role in all medical settings, so turn to this trusted volume for nearly any medical abbreviation you might encounter. - Symbols section makes it easier to locate unusual or seldom-used symbols. - Convenient alphabetical format allows you to find the entry you need more intuitively. - More than 90,000 entries and definitions. - Many new and updated entries including terminology in expanding specialties, such as Nursing; Physical, Occupational, and Speech Therapies; Transcription and Coding; Computer and Technical Fields. - New section on abbreviations to avoid, including Joint Commission abbreviations that are not to be used. - Incorporates updates suggested by the Institute for Safe Medication Practices (ISMP).
