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Author: Lorraine N. Salomon
Publisher: Gazelle Book Services, Limited
ISBN: 9781631176784
Category : Alzheime's disease
Languages : en
Pages : 150
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Book Description
The healthy human brain contains tens of billions of neurons, specialized cells that process and transmit information via electrical and chemical signals. While the brain may shrink to some degree in healthy aging, it does not lose neurons in large numbers. In Alzheimer's disease, however, damage is widespread as many neurons stop functioning, lose connections with other neurons, and die. Alzheimer's disrupts processes vital to neurons and their networks, including communication, metabolism, and repair. At first, the disease typically destroys neurons and their connections in parts of the brain involved in memory, including the entorhinal cortex and the hippocampus. It later affects areas in the cerebral cortex responsible for language, reasoning, and social behavior. Eventually, many other areas of the brain are damaged, and a person with Alzheimer's becomes helpless and unresponsive to the outside world. This book provides a comparison of international approached to dealing with Alzheimer's disease and dementia, as well as discusses the effect this disease has on the brain and its function.
Author: Lorraine N. Salomon
Publisher: Nova Science Publishers
ISBN: 9781631176777
Category : Alzheimer's disease
Languages : en
Pages : 0
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Book Description
The healthy human brain contains tens of billions of neurons, specialized cells that process and transmit information via electrical and chemical signals. While the brain may shrink to some degree in healthy aging, it does not lose neurons in large numbers. In Alzheimer's disease, however, damage is widespread as many neurons stop functioning, lose connections with other neurons, and die. Alzheimer's disrupts processes vital to neurons and their networks, including communication, metabolism, and repair. At first, the disease typically destroys neurons and their connections in parts of the brain involved in memory, including the entorhinal cortex and the hippocampus. It later affects areas in the cerebral cortex responsible for language, reasoning, and social behavior. Eventually, many other areas of the brain are damaged, and a person with Alzheimer's becomes helpless and unresponsive to the outside world. This book provides a comparison of international approached to dealing with Alzheimer's disease and dementia, as well as discusses the effect this disease has on the brain and its function.
Author: Lorraine N. Salomon
Publisher: Gazelle Book Services, Limited
ISBN: 9781631176784
Category : Alzheime's disease
Languages : en
Pages : 150
Get Book Here
Book Description
The healthy human brain contains tens of billions of neurons, specialized cells that process and transmit information via electrical and chemical signals. While the brain may shrink to some degree in healthy aging, it does not lose neurons in large numbers. In Alzheimer's disease, however, damage is widespread as many neurons stop functioning, lose connections with other neurons, and die. Alzheimer's disrupts processes vital to neurons and their networks, including communication, metabolism, and repair. At first, the disease typically destroys neurons and their connections in parts of the brain involved in memory, including the entorhinal cortex and the hippocampus. It later affects areas in the cerebral cortex responsible for language, reasoning, and social behavior. Eventually, many other areas of the brain are damaged, and a person with Alzheimer's becomes helpless and unresponsive to the outside world. This book provides a comparison of international approached to dealing with Alzheimer's disease and dementia, as well as discusses the effect this disease has on the brain and its function.
Author: Jeffrey Cummings
Publisher: Cambridge University Press
ISBN: 1108838669
Category : Business & Economics
Languages : en
Pages : 575
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Book Description
Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Author: Menghis Bairu
Publisher: Academic Press
ISBN: 0124115306
Category : Medical
Languages : en
Pages : 428
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Book Description
Global Clinical Trials for Alzheimer’s Disease is a handy one-stop reference for researchers and physicians planning and conducting global clinical trials in this area. This book addresses important considerations that may arise during the successful design and execution of these trials, including site selection, local regulatory issues, pharmacogenomics, ethical matters and much more. Given the saturation of traditional clinical trial markets and the worldwide progression of Alzheimer’s disease, there is a need to focus on clinical trials in emerging markets and developing countries. This book provides you with a practical approach to recognizing the opportunities and tackling the challenges that are present during the planning and execution of global clinical trials for Alzheimer’s disease. Written by leading experts with hands-on experience in designing and running global Alzheimer’s disease and other neurodegenerative diseases clinical trials A step-by-step guide that provides critical information on the design, conduct and standardization necessary to effectively execute clinical trials and accelerate drug development in this area Includes practical examples, ethical considerations, lessons learned and other valuable tools to aid the planning and implementation of Alzheimer’s disease global clinical trials in emerging markets and developing countries
Author: Dick-Muehlke, Cordula
Publisher: IGI Global
ISBN: 1466684798
Category : Health & Fitness
Languages : en
Pages : 463
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Book Description
Cognitive impairment, through Alzheimer’s disease or other related forms of dementia, is a serious concern for afflicted individuals and their caregivers. Understanding patients’ mental state and combatting social stigmas are important considerations in caring for cognitively impaired individuals. Psychosocial Studies of the Individual's Changing Perspectives in Alzheimer's Disease describes programs and strategies that professional and family caregivers can implement to engage and improve the quality of life of persons suffering from cognitive impairment. Including real-world cases by international experts and a personal approach to the subject, this book is an important resource for caregivers, researchers, and families living with dementia.
Author: Jack C. de la Torre
Publisher: Springer
ISBN: 3319340573
Category : Medical
Languages : en
Pages : 256
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Book Description
This compelling text provides an overview of the available technology for early detection and therapeutic management of vascular risk factors to Alzheimer’s before severe cognitive impairment symptoms appear. Chapters bring the reader from the trackless clinical research that has characterized Alzheimer’s progress for the last 20 years, to a nexus of new ideas and concepts that can change our outlook of this dementia. In-depth examinations of various hypotheses, preventive measures, current and prospective treatments are openly and clearly explored. The author discusses in depth his proposal of the vascular hypothesis of Alzheimer's disease which has become a mother-lode for basic and clinical studies and a key approach to the prevention of this dementia.Alzheimer’s Turning Point offers professionals, students and those looking to learn more about this disorder a fresh clinical perspective of this devastating disease.
Author: E. Meyer
Publisher: Springer Science & Business Media
ISBN: 1468457276
Category : Science
Languages : en
Pages : 387
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Book Description
Alzheimer's disease afflicts up to 1 in 5 people over the age of 65 years and causes untold suffering of the patient and their family. The cause of this disease is unknown; indeed, evidence increasingly suggests that there may be multiple Alzheimer-type syndromes with different etiologies, analogous to different types of psychosis. Currently there are no means to prevent the disease, slow its progress or reverse its neurodegenerative consequences. With few exceptions, clinical trials of a variety of compounds have resulted in patient responses that are disappointing with respect to both the proportion of responders and the magnitude of the responses. Novel approaches to the treatment of Alzheimer's disease are clearly warranted. For this reason, we organized the First Suncoast Workshop on the Neurobiology of Aging in St. Petersburg, Florida, which took place from February 26-March 1, 1989. This workshop focused on novel treatments and models for Alzheimer's disease and represented a cooperative venture among academia, government and industry, both in its participants and sponsorship. The Center for the Neurobiology of Aging at the University of Florida, the National Institute on Aging and Taiho Pharmaceutical Corporation in Japan sponsored the workshop in which scientists from the North America, Europe, Japan and other parts of Asia participated.
Author: Amy Borenstein
Publisher: Academic Press
ISBN: 0124171540
Category : Psychology
Languages : en
Pages : 467
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Book Description
Alzheimer's Disease: Lifecourse Perspectives on Risk Reduction summarizes the growing body of knowledge on the distribution and causes of Alzheimer’s disease (AD) in human populations, providing the reader with knowledge on how we define the disease and what its risk and protective factors are in the context of a life-course approach. At the conclusion of the book, the reader will understand why Alzheimer’s disease likely begins at conception, then progresses through early-life and adult risk factors that ultimately impact the balance between pathologic insults in the brain and the ability of the brain to modify disease symptoms. In contrast to edited volumes that may have little cohesion, this book focuses on an integrated life-course approach to the epidemiology of dementia, in particular, Alzheimer’s disease. Reviews the current science surrounding Alzheimer’s disease Provides a primer of foundational knowledge on the disease's epidemiology and biostatistics Utilizes a life-course approach, providing a novel and integrated view of the evolution of this illness from genes to brain reserve Uses the ‘threshold model’—a theory first described by Dr. Mortimer and widely accepted today—which incorporates the idea of risk factors for the pathology and expression of the disease Proposes that improving brain health through modifiable behaviors can delay disease onset until a later age Examines the future of prevention of Alzheimer’s disease, a subject of great current interest
Author: Chau Trinh-Shevrin
Publisher: John Wiley & Sons
ISBN: 1394204140
Category : Medical
Languages : en
Pages : 182
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Book Description
Gain a thorough understanding of the determinants of health among aging populations, how disparities arise in diverse communities, and what can be done Reducing health disparities among older people is critical to slowing or reversing the individual and societal impacts of aging-related conditions like Alzheimer's and dementia. The field of population science can help us understand disparities and prevent them using community-wide strategies. Population Science Methods and Approaches to Aging and Alzheimer's Disease and Related Dementias Research offers an overview of the population health approach, applying this framework to aging-related conditions and their determinants. By working hand-in-hand with diverse communities to address these conditions we can develop primary and secondary prevention strategies that can increase health equity for all Americans. Included topics range from population health trends and approaches to understanding community and patient engagement to caregiver perspectives and emerging trends. Learn about the population science approach to understanding aging-related health concerns in diverse communities See how factors like race, income, sexual orientation, sleep, and community engagement affect Alzheimer's and related dementias Read about proactive approaches to primary and secondary prevention within aging populations Discover emerging research and public health initiatives currently underway to promote health equity Students, researchers, and practitioners alike will benefit from this primer on participatory approaches to reducing health disparities. This introduction to the landscape of aging research in the most vulnerable of our communities will facilitate creativity, compassion, and meaningful next steps in biomedical and socioecological research, community support, and clinical care.
Author: World Health Organization
Publisher:
ISBN: 9789241564458
Category : Medical
Languages : en
Pages : 102
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Book Description
The report “Dementia: a public health priority” has been jointly developed by WHO and Alzheimer's Disease International. The purpose of this report is to raise awareness of dementia as a public health priority, to articulate a public health approach and to advocate for action at international and national levels.
