Intermittent Hypoxia and Human Diseases

Intermittent Hypoxia and Human Diseases PDF Author: Lei Xi
Publisher: Springer Science & Business Media
ISBN: 1447129067
Category : Medical
Languages : en
Pages : 310

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Book Description
Intermittent hypoxia can cause significant structural and functional impact on the systemic, organic, cellular and molecular processes of human physiology and pathophysiology. This book focuses on the most updated scientific understanding of the adaptive (beneficial) and maladaptive (detrimental) responses to intermittent hypoxia and their potential pathogenetic or prophylactic roles in the development and progression of major human diseases. This is a comprehensive monograph for clinicians, research scientists, academic faculty, postgraduate and medical students, and allied health professionals who are interested in enhancing their up-to-date knowledge of intermittent hypoxia research and its translational applications in preventing and treating major human diseases.

Intermittent Hypoxia and Human Diseases

Intermittent Hypoxia and Human Diseases PDF Author: Lei Xi
Publisher: Springer Science & Business Media
ISBN: 1447129067
Category : Medical
Languages : en
Pages : 310

Get Book

Book Description
Intermittent hypoxia can cause significant structural and functional impact on the systemic, organic, cellular and molecular processes of human physiology and pathophysiology. This book focuses on the most updated scientific understanding of the adaptive (beneficial) and maladaptive (detrimental) responses to intermittent hypoxia and their potential pathogenetic or prophylactic roles in the development and progression of major human diseases. This is a comprehensive monograph for clinicians, research scientists, academic faculty, postgraduate and medical students, and allied health professionals who are interested in enhancing their up-to-date knowledge of intermittent hypoxia research and its translational applications in preventing and treating major human diseases.

Hypoxia

Hypoxia PDF Author: Robert C. Roach
Publisher: Springer Science & Business Media
ISBN: 9780306466960
Category : Medical
Languages : en
Pages : 466

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Book Description
Hypoxia remains a constant threat throughout life. It is for this reason that the International Hypoxia Society strives to maintain a near quarter century tradition of presenting a stimulating blend of clinical and basic science discussions. International experts from many fields have focused on the state-of-the-art discoveries in normal and pathophysiological responses to hypoxia. Topics in this volume include gene-environment interactions, a theme developed in both a clinical context regarding exercise and hypoxia, as well as in native populations living in high altitudes. Furthermore, experts in the field have combined topics such as skeletal muscle angiogenesis and hypoxia, high altitude pulmonary edema, new insights into the biology of the erythropoietin receptor, and the latest advances in cardiorespiratory control in hypoxia. This volume explores the fields of anatomy, cardiology, biological transport, and biomedical engineering among many others.

Intermittent Hypoxia

Intermittent Hypoxia PDF Author: Lei Xi
Publisher: Nova Science Pub Incorporated
ISBN: 9781622577101
Category : Medical
Languages : en
Pages : 615

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Book Description
In consolidation of the most updated experimental results and perspectives from diverse research fields on a main theme - Intermittent Hypoxia, this book encompasses the structural, physiological, pathophysiological, biochemical, genetic, metabolic, and therapeutic aspects of intermittent hypoxia and provides an open forum to promote the bench-to-bed translational implications of both adaptive (beneficial) and maladaptive (detrimental) responses to intermittent hypoxia in animals and humans. Authored by 74 leading scientists from 17 countries in Asia, Europe, North America, and Oceana, the 30 chapters are grouped under 7 different sections covering the profound effects of intermittent hypoxia particularly on cardiovascular, respiratory, nervous, and skeletal muscular systems. Special attentions are paid to the protective or injurious roles played by intermittent hypoxia and their underlying cellular and molecular mechanisms in several major human diseases such as acute myocardial infarction, stroke, sleep apnea, and Parkinsons disease. Several chapters have also reviewed the use of intermittent hypoxia training for enhancing exercise performance in elite athletes. Overall, as endorsed by Professor John B. West (Member, Institute of Medicine, National Academy of Sciences of U.S.A.; Editor-in-Chief, High Altitude Medicine and Biology) through his Foreword for the book, this is the most comprehensive monograph to date on the topic of intermittent hypoxia, which can cause significant structural and functional impact on the systemic, organic, cellular and molecular processes of human physiology and pathophysiology. Hence, this book could serve as a thorough reference for research scientists, physicians, academic faculty, graduate and medical students, athletic coaches and trainers, who are interested in enhancing their knowledge about the past, present, and future of intermittent hypoxia research and its translational applications for prevention and treatment of major diseases and improving exercise performance.

Physiological Responses to Intermittent Hypoxia in Humans

Physiological Responses to Intermittent Hypoxia in Humans PDF Author: Jon C. Kolb
Publisher: Universal-Publishers
ISBN: 1581122411
Category : Medical
Languages : en
Pages : 196

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Book Description
Recently, endurance athletes and high altitude climbers have gained access to commercially available, portable normobaric hypoxic chambers. Intermittent exposures to hypoxia in these chambers may elicit adaptations similar to those observed during acclimatization to altitude. Manufactures of these systems purport that intermittent exposures may elicit adaptations similar to those observed in response to the hypoxia of high altitude, however there have been no reports in the scientific literature that ventilatory acclimatization or alterations in cerebrovascular dynamics occur following repeated episodes in the portable chambers. The main conclusions are that an intermittent normobaric hypoxic intervention, consisting of five consecutive overnight exposures to a simulated altitude of 4300m, elicits perturbations in the acute cerebrovascular and ventilatory responses to both hypoxia and hypercapnia, which are similar to changes following chronic altitude exposure. Individual variability to intermittent hypoxia may have an impact on the rate at which the process of acclimatization proceeds. The extent of physiological and symptomatic responses to intermittent hypoxia are likely to be associated with the severity of hypoxia as well as the length and number of recurrent episodes of hypoxia.

Intermittent Hypoxia and Human Diseases

Intermittent Hypoxia and Human Diseases PDF Author: Springer
Publisher:
ISBN: 9781447129073
Category :
Languages : en
Pages : 330

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Book Description


Atherosclerosis, Arteriosclerosis and Arteriolosclerosis

Atherosclerosis, Arteriosclerosis and Arteriolosclerosis PDF Author: Luigi Gianturco
Publisher: BoD – Books on Demand
ISBN: 1838803033
Category : Medical
Languages : en
Pages : 86

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Book Description
With high morbidity and mortality rates, atherosclerosis (ATS) is a major concern worldwide. This book provides comprehensive information on ATS, including chapters on cardiovascular disease and obstructive sleep apnea, rheumatology and cardiovascular risk, and the differences of ATS among men and women. Let’s hope for the best and thank you to all my team for collaborating in this book production. In particular, thanks • to Bruno (my expert colleague) and Aurel (my secretary) for analyzing and reading with me all the texts • to Vincenzo, Stefano and Andrea for English evaluation • and finally to Rebecca (my future wife) for sustaining me in all professional activities giving me power in daily life!

Evidence-based Pediatrics and Child Health

Evidence-based Pediatrics and Child Health PDF Author: Virginia Moyer
Publisher: John Wiley & Sons
ISBN: 1405140259
Category : Medical
Languages : en
Pages : 544

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Book Description
Evidence Based Pediatrics and Child Health is a ground-breaking new text on pediatrics and child care management, using evidence based approach. It covers all the major childhood conditions and contains the features of both a handbook and a reference text. Each chapter combines both advice on management and how best to practice evidence based medicine with reviews of all the available evidence in a specific area. The goal of the book is to help pediatricians and others who care for children to provide the best possible care by combining the best, most current evidence with special circumstances of each individual patient.

Brain Hypoxia and Ischemia

Brain Hypoxia and Ischemia PDF Author: Gabriel G. Haddad
Publisher: Springer Science & Business Media
ISBN: 1603275797
Category : Medical
Languages : en
Pages : 268

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Book Description
Brain Hypoxia and Ischemia explores the various aspects of cell death and survival that are crucial for understanding the basic mechanisms underlying brain hypoxia and ischemia. Chapters focus on a panorama of issues including the role of ion channels/transporters, mitochondria and apoptotic mechanisms, the roles of glutamate/NMDA, mechanisms in penumbral cells and the importance of intermittent hypoxia and gene regulation under these stressful conditions. The volume explores findings from both mammalian and invertebrate model systems and their applicability to human systems and diseases. Careful consideration is also given to differences in hypoxia and ischemia across development. This volume aims to increase the understanding of these mechanisms and to stimulate research on better diagnosis and treatment of diseases that afflict the brain and potentially other organs when O2 levels are dysregulated. Brain Hypoxia and Ischemia is designed for neuroscientists, clinicians and medical/graduate students for use in both basic research and clinical practice.

Hypoxia and Anoxia

Hypoxia and Anoxia PDF Author: Kusal Das
Publisher: BoD – Books on Demand
ISBN: 1789848288
Category : Medical
Languages : en
Pages : 146

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Book Description
The molecular deprivation of oxygen is manifested by hypoxia, a deficiency of oxygen and anoxia, or the absence of oxygen supply to the tissues. This book entitled Hypoxia and Anoxia will cover a broad range of understanding on hypoxia and anoxia from molecular mechanisms to pathophysiology. Hypoxia and anoxia stimulate multiple systems through specific cell signal transduction pathways and regulate several transcriptional factors like HIF-1, REST to encode genes for VEGF, Epo, etc. This book will also highlight different types of hypoxia and anoxia along with their impact on apoptosis, cardiovascular pathophysiology, and glucose regulatory mechanisms. This book will be a ready reckoner to give a deep understanding of the oxygen-sensing environment in vivo for researchers, academicians, and clinicians throughout the world.

Hypoxia and the Circulation

Hypoxia and the Circulation PDF Author: Robert Roach
Publisher: Springer Science & Business Media
ISBN: 0387754342
Category : Medical
Languages : en
Pages : 350

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Book Description
Just one of a series of volumes on differing aspects of hypoxia, this authoritative text focuses on cutting-edge research at the interface of hypoxia and biomedicine. Hypoxia – or lack of oxygen – is a constant threat to the human body and its vital organs, one that can take its toll in a number of situations. There are many situations in which the threat is heightened in health and disease, but mechanisms have evolved to lessen its detrimental effects. The International Hypoxia Symposia was founded to enable scientists, clinicians, physiologists, immunologists, mountaineers and other interested individuals to share their experiences of the situations associated with the lack of oxygen and the adaptations that allow us to survive.