Innovative Radiopharmaceuticals in Oncology and Neurology

Innovative Radiopharmaceuticals in Oncology and Neurology PDF Author: Françoise Kraeber-Bodéré
Publisher: Frontiers Media SA
ISBN: 2889451747
Category :
Languages : en
Pages : 116

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Book Description
The aim of this Research Topic was to assemble a series of articles describing basic, preclinical and clinical research studies on radiopharmaceuticals and nuclear medicine. The articles were written by attendees of the third Nuclear Technologies for Health Symposium (NTHS, 10th-11th March 2015, Nantes, Frances) under the auspices of the IRON LabEx (Innovative Radiopharmaceuticals for Oncology and Neurology Laboratory of Excellence). This French network, gathering approximately 160 scientists from 12 academic research teams (Funded by “investissements d’Avenir”), fosters transdisciplinary projects between teams with expertise in chemistry, radiochemistry, radiopharmacy, formulation, biology, nuclear medicine and medical physics. The 12 articles within this resulting eBook present a series of comprehensive reviews and original research papers on multimodality imaging and targeted radionuclide therapy; illustrating the different facets of studies currently conducted in these domains.

Innovative Radiopharmaceuticals in Oncology and Neurology

Innovative Radiopharmaceuticals in Oncology and Neurology PDF Author: Françoise Kraeber-Bodéré
Publisher: Frontiers Media SA
ISBN: 2889451747
Category :
Languages : en
Pages : 116

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Book Description
The aim of this Research Topic was to assemble a series of articles describing basic, preclinical and clinical research studies on radiopharmaceuticals and nuclear medicine. The articles were written by attendees of the third Nuclear Technologies for Health Symposium (NTHS, 10th-11th March 2015, Nantes, Frances) under the auspices of the IRON LabEx (Innovative Radiopharmaceuticals for Oncology and Neurology Laboratory of Excellence). This French network, gathering approximately 160 scientists from 12 academic research teams (Funded by “investissements d’Avenir”), fosters transdisciplinary projects between teams with expertise in chemistry, radiochemistry, radiopharmacy, formulation, biology, nuclear medicine and medical physics. The 12 articles within this resulting eBook present a series of comprehensive reviews and original research papers on multimodality imaging and targeted radionuclide therapy; illustrating the different facets of studies currently conducted in these domains.

Advanced Imaging and Therapy in Neuro-Oncology

Advanced Imaging and Therapy in Neuro-Oncology PDF Author: Egesta Lopci
Publisher: Springer
ISBN: 9783031593406
Category : Medical
Languages : en
Pages : 0

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Book Description
This book covers all diagnostic and therapeutic aspects of neuro-oncological diseases. In the last decade, the management of brain tumors has been revolutionized following the new WHO classification and thanks to the introduction of molecular markers into the clinical routine. From an imaging point of view, the continuous technological developments and the implementation of various radiopharmaceuticals have paved the way to new clinical indications and has helped optimize patient management. In this context, a major breakthrough could derive from the introduction of radiomics and artificial intelligence in the diagnostic and therapeutic pathway. Not forgetting the emerging role of heavy-ion therapy as a complement to the innovative drugs and treatments adopted in medical oncology and radiation therapy. In the present book, all above-mentioned aspects are covered, starting with the novel standards for the WHO classification of brain tumors, to the up-to-date surgical techniques and advanced therapeutic approaches, passing through the currently available imaging modalities and ongoing developments embracing both radiology and nuclear medicine discipline. Imaging represents indeed the “trait d'union” for all the arguments described in the book; therefore, in most chapters there are dedicated sessions focused on the role of imaging in each specific context. The publication aims to fill the gap between the clinicians and all professionals directly involved in the management of patients with brain tumors and the newest scientific outreach. Moreover, thanks to the comprehensive insight into the latest technological developments, scientists and researchers interested in the topic will find the book a useful tool for future studies and perspective discoveries.

Handbook of Radiopharmaceuticals

Handbook of Radiopharmaceuticals PDF Author: Michael R. Kilbourn
Publisher: John Wiley & Sons
ISBN: 1119500567
Category : Science
Languages : en
Pages : 768

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Book Description
Sorgfältig aktualisierte Neuauflage dieses wegweisenden Referenzwerk der radiopharmazeutischen Wissenschaften Die 2. Auflage des Handbook of Radiopharmaceuticals wirft einen umfassenden analytischen Blick auf das Fachgebiet und bietet aktuelle Informationen zu zentralen Themen, u. a. die Herstellung von Radionukliden, synthetische Methoden, Entwicklungen in der Radiopharmazie, Regelwerke, und zu einer Fülle praktischer Anwendungen. Als wertvolles Nachschlagewerk für Einsteiger und erfahrene Praktiker untersucht diese Publikation die neuesten Konzepte und Fragestellungen unter Berücksichtigung des gezielten Einsatzes diagnostischer und therapeutischer Radiopharmazeutika. Die Beiträge stammen von Experten verschiedenster Unterdisziplinen und lassen den Leser eintauchen in die Radiochemie, Nuklearmedizin, molekulare Bildgebung u.v.m. Die Nuklearmedizin und radiopharmazeutischen Wissenschaften haben sich seit Veröffentlichung der 1. Auflage stark verändert. Neue Radiopharmazeutika für Diagnostik und Therapie wurden von der FDA zugelassen, klinische PET- und SPECT-Scans haben drastisch zugenommen und Fortschritte im Bereich Künstliche Intelligenz haben zu signifikant verbesserten Forschungsverfahren geführt. Diese vollständig überarbeitete Auflage stellt den derzeitigen Erkenntnisstand des Fachgebiets vor, ergänzt um aktualisierte und neue Inhalte. Neue Kapitel beschäftigen sich mit heutigen Good Manufacturing Practice, regulatorischen Entwicklungen und neuen Ansätzen bei der Qualitätskontrolle. Damit wird sichergestellt, dass die Leserschaft über die aufregenden Entwicklungen der letzten Jahre rundum im Bilde ist. Dieses wichtige Referenzwerk - bietet durchgängig neue und überarbeitete Inhalte. - deckt zentrale Anwendungsbereiche in der Diagnostik und Therapie ab, für die Onkologie, Neurologie und Kardiologie. - unterstreicht die multidisziplinäre Ausrichtung der radiopharmazeutischen Wissenschaften. - zeigt, wie Pharmaunternehmen mit modernen Bildgebungsverfahren der Radiopharmazie neue Medikamente entwickeln. - untersucht heutige und neue Anwendungen der Positronen-Emissions-Tomographie (PET) und Single-Photonen-Emissions-Computertomographie (SPECT). Die Herausgeber sind anerkannte Experten der Fachrichtungen Radiochemie und PET-Bildgebung. Die 2. Auflage des Handbook of Radiopharmaceuticals: Radiochemistry and Applications ist ein Muss für Postdoktoranden, Forscher und Fachexperten in der Pharmazeutischen Industrie und richtet sich ebenso an die akademische Forschung und Lehre, an Graduierte und Einsteiger in das Fachgebiet der Radiopharmazeutika.

Advancing Nuclear Medicine Through Innovation

Advancing Nuclear Medicine Through Innovation PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309134153
Category : Medical
Languages : en
Pages : 173

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Book Description
Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

PET Radiopharmaceuticals

PET Radiopharmaceuticals PDF Author: James R. Ballinger
Publisher: Springer
ISBN: 9783031102707
Category : Medical
Languages : en
Pages : 0

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Book Description
This book presents in a consistent format data on ~50 PET radiopharmaceuticals in clinical use. Parameters include basic chemical data, normal biodistribution and excretion, activity administered, radiation dosimetry, patient preparation, and clinical utility, together with a few key references. In some cases a representative image is presented. The organisation is first by clinical specialty (oncology, cardiology, neurology) and within each section by radionuclide (F-18, C-11, etc). This book will be of interest mostly to nuclear medicine physicians and trainees, but also to a wider medical community including radiologists, oncologists and radiotherapists.

Targeted Radionuclide Therapy

Targeted Radionuclide Therapy PDF Author: Tod W. Speer
Publisher: Lippincott Williams & Wilkins
ISBN: 1451153260
Category : Medical
Languages : en
Pages : 564

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Book Description
Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.

Radiopharmaceutical Chemistry

Radiopharmaceutical Chemistry PDF Author: Jason S. Lewis
Publisher: Springer
ISBN: 3319989472
Category : Medical
Languages : en
Pages : 648

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Book Description
This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic. The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like “The Production of Radionuclides” and “Basics of Radiochemistry”. The second section is the main focus of the book. In this section, each chapter’s author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a “Best of the Rest” chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including “Bioconjugation Methods,” “Click Chemistry in Radiochemistry”, and “Radiochemical Instrumentation.” This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.

Design and Application of Innovative Local Treatments in Glioblastoma and Other Cancers

Design and Application of Innovative Local Treatments in Glioblastoma and Other Cancers PDF Author: Emmanuel Garcion
Publisher: Frontiers Media SA
ISBN: 2889666581
Category : Science
Languages : en
Pages : 125

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Book Description


Lipid Nanoparticles as a Novel Strategy to Deliver Bioactive Molecules

Lipid Nanoparticles as a Novel Strategy to Deliver Bioactive Molecules PDF Author: Alan Talevi
Publisher: Frontiers Media SA
ISBN: 2889666972
Category : Science
Languages : en
Pages : 135

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Book Description


Green Synthesis in Nanomedicine and Human Health

Green Synthesis in Nanomedicine and Human Health PDF Author: Richard L. K. Glover
Publisher: CRC Press
ISBN: 100035119X
Category : Science
Languages : en
Pages : 240

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Book Description
Green synthesis is an emerging method for deriving nanoparticles present in natural plants for use in nanomedicine. Written by experts in the field, Green Synthesis in Nanomedicine and Human Health showcases the exciting developments of this specialty and its potential for promoting human health and well-being. This book gives practical information on novel preparation methods for identifying nanoparticles present in natural plants. It discusses applications of nanoparticles in combating communicable, non-communicable and vector-borne diseases. It also explores the potential for nanoparticles to combat antimicrobial resistance through improvements in treatment methods, diagnostics and drug delivery systems. Features scientific evidence of opportunities for integrating indigenous flora into nanomedicine to develop cost-effective therapeutic and diagnostic solutions for diseases, including cancer, tuberculosis, malaria and diabetes. Places green synthesis and nanomedicine in the African orthodox and traditional healthcare context. Provides policymakers with scientific evidence to inform policies for controlling or mitigating dangerous diseases. This book is essential reading for students, scientists, policymakers and practitioners of nanotechnology, and will appeal to anyone with an interest in integrating traditional African healthcare and Western medicine.