Inhibition and Postinhibitory Excitation in Guinea-pig Taenia Caeci PDF Download
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Author: Adrianus Jacobus Johannes Maas
Publisher:
ISBN:
Category : Excitation (Physiology)
Languages : en
Pages : 148
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Author: Adrianus Jacobus Johannes Maas
Publisher:
ISBN:
Category : Excitation (Physiology)
Languages : en
Pages : 148
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Book Description
Author: David Paton
Publisher: Springer Science & Business Media
ISBN: 1468448862
Category : Medical
Languages : en
Pages : 385
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Book Description
In their classic paper in 1929, Drury and Szent-Gyorgyi described a number of the important cardiovascular actions of adenosine. Another thirty years were to pass before the possible physiological role of adenosine in coronary vasodilation was studied by Berne and others. Since then, there has been a tremendous increase in research into the actions of adenosine. Workers from many disciplines have employed a wide variety of techniques, since adenosine is a product of and a substrate for a number of metabolic pathways, is transported into cells, and acts at discrete receptor sites to modulate the activity of adenylate cyclase and to produce important actions on many cells and tissues including platelets, adipo cytes, heart, blood vessels, and other smooth muscles. International symposia on the actions of adenosine were held in 1978, 1981, and 1982, and the proceedings of these symposia have been published (Baer and Drummond, 1979; Daly et at., 1983; Berne et at., 1983). Since it is not the primary purpose of the present volume to review our current understanding of the nu merous actions of adenosine, these volumes should be consulted for such details. Rather, the present volume has been planned to provide both graduate students and investigators in pharmacology and related disciplines with a summary of some of the methods now available for the study of the actions of adenosine and, in particular, to highlight their possible uses and limitations.
Author: Arnold Schwartz
Publisher:
ISBN:
Category : Pharmacology
Languages : en
Pages : 408
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Author: A. K. Grover
Publisher: Springer Science & Business Media
ISBN: 1461251729
Category : Science
Languages : en
Pages : 498
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Book Description
In organizing the present volume, we had two intentions. The first was to present the best current understanding of the mechanisms of calcium mobilization during excitation contraction coupling of smooth muscle at a level suited to the needs of professionals interested in smooth muscle pharmacology and pathophysiology, while remaining appreciable by graduate and medical students. The second intention was to provide in sight into present-day controversies, as well as the latest ad vances achieved by researchers in this field. Thus, we have thor oughly discussed both the techniques and the concepts derived from their application. An attempt has also been made here to answer a number of profoundly important questions: What are the mechanisms and agents responsible for the control of contractility? What are the accompanying changes in the state of intracellular calcium ions and the mechanisms responsible for them? How does the regula tion of contractility occur directly at the level of the actomyosin activity? What role do gap junctions play in cell-to-cell coupling? What are the roles of cholinergic, adrenergic, peptidergic, and nonadrenergic noncholinergic interactions in calcium mobiliza tion in smooth muscle? What changes occur in hypertension? The impact of these recent techniques on future research is also reflected upon.
Author: Jan D. Huizinga
Publisher:
ISBN:
Category : Gastrointestinal system
Languages : en
Pages : 132
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Author: John R. Pappenheimer
Publisher:
ISBN: 9780195207910
Category :
Languages : en
Pages : 888
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Author:
Publisher:
ISBN:
Category : Gastrointestinal system
Languages : en
Pages : 890
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Author: John Newport Langley
Publisher:
ISBN:
Category : Autonomic nervous system
Languages : en
Pages : 96
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Book Description
Langley defined the autonomic nervous system as an efferent system. He divided it into the orthosympathetic and the parasympathetic.
Author: Nicholas T. Carnevale
Publisher: Cambridge University Press
ISBN: 1139447831
Category : Medical
Languages : en
Pages : 399
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Book Description
The authoritative reference on NEURON, the simulation environment for modeling biological neurons and neural networks that enjoys wide use in the experimental and computational neuroscience communities. This book shows how to use NEURON to construct and apply empirically based models. Written primarily for neuroscience investigators, teachers, and students, it assumes no previous knowledge of computer programming or numerical methods. Readers with a background in the physical sciences or mathematics, who have some knowledge about brain cells and circuits and are interested in computational modeling, will also find it helpful. The NEURON Book covers material that ranges from the inner workings of this program, to practical considerations involved in specifying the anatomical and biophysical properties that are to be represented in models. It uses a problem-solving approach, with many working examples that readers can try for themselves.
Author:
Publisher:
ISBN:
Category : Agriculture
Languages : en
Pages : 1104
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Book Description
