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Author: Paul G. Winyard
Publisher: Springer Science & Business Media
ISBN: 1592593747
Category : Medical
Languages : en
Pages : 373
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Book Description
Inflammation has been described as the basis of many pathologies of human disease. When one considers the updated signs of inflammation, they would be vasodilation, cell migration, and, in the case of chronic inflam- tion, cell proliferation, often with an underlying autoimmune basis. Gen- ally, inflammation may be divided into acute, chronic, and autoimmune, - though the editors believe that most, if not all, chronic states are often the result of an autoimmune response to an endogenous antigen. Thus, a proper understanding of the inflammatory basis may provide clues to new therap- tic targets not only in classical inflammatory diseases, but atherosclerosis, cancer, and ischemic heart disease as well. The lack of advances in classical inflammatory diseases, such as rh- matoid arthritis, may in part arise from a failure to classify the disease into different forms. That different forms exist is exemplified in patients with d- fering responses to existing antiinflammatory drugs, ranging from nonresponders to very positive responders for a particular nonsteroidal an- inflammatory drug (NSAID). Though researchers have progressively unr- eled the mechanisms, the story is far from complete. It should also be noted that the inflammatory response is part of the innate immune response, or to use John Hunter’s words in 1795, “inflammation is a salutary response.” That may be applied in particular to the defensive response to invading micro- ganisms.
Author: Paul G. Winyard
Publisher: Springer Science & Business Media
ISBN: 1592593747
Category : Medical
Languages : en
Pages : 373
Get Book Here
Book Description
Inflammation has been described as the basis of many pathologies of human disease. When one considers the updated signs of inflammation, they would be vasodilation, cell migration, and, in the case of chronic inflam- tion, cell proliferation, often with an underlying autoimmune basis. Gen- ally, inflammation may be divided into acute, chronic, and autoimmune, - though the editors believe that most, if not all, chronic states are often the result of an autoimmune response to an endogenous antigen. Thus, a proper understanding of the inflammatory basis may provide clues to new therap- tic targets not only in classical inflammatory diseases, but atherosclerosis, cancer, and ischemic heart disease as well. The lack of advances in classical inflammatory diseases, such as rh- matoid arthritis, may in part arise from a failure to classify the disease into different forms. That different forms exist is exemplified in patients with d- fering responses to existing antiinflammatory drugs, ranging from nonresponders to very positive responders for a particular nonsteroidal an- inflammatory drug (NSAID). Though researchers have progressively unr- eled the mechanisms, the story is far from complete. It should also be noted that the inflammatory response is part of the innate immune response, or to use John Hunter’s words in 1795, “inflammation is a salutary response.” That may be applied in particular to the defensive response to invading micro- ganisms.
Author: Björn E. Clausen
Publisher: Humana
ISBN: 9781493967841
Category : Medical
Languages : en
Pages : 0
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Book Description
This volume presents a broad selection of cutting-edge methods and tools that will enable the reader to investigate the multi-faceted manifestations of inflammation. Inflammation: Methods and Protocols is divided into four sections: the first three sections describe protocols investigating immune-mediated inflammatory disease models affecting barrier organs to the environment; the skin, the lung, and the intestinal and oral mucosa. The fourth section illustrates inflammatory disease models of the brain, joints, and vasculature. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and practical, Inflammation: Methods and Protocols aims to inspire the experienced investigator and the young experimenter alike to disentangle the fascinating process of inflammation.
Author: Brendan J. Jenkins
Publisher: Humana
ISBN: 9781071633335
Category : Medical
Languages : en
Pages : 0
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Book Description
This second edition volume expands on the previous edition with an update on the broad spectrum of research models, techniques, and protocols used in laboratories by basic and clinical researchers. The chapters in this book are divided into two parts. Part One discusses the latest findings on the development and characterization of representative research models for chronic immune-based diseases and inflammation-associated cancers. Part Two covers biochemical, molecular, and cellular biological techniques that are commonly used to dissect the molecular mechanisms and cellular processes that drive the pathogenesis of certain disease states. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Inflammation and Cancer: Methods and Protocols, Second Edition is a valuable resource for those with a diverse range of laboratory-based experience, ranging from novice undergraduate students to established basic or clinical researchers who wish to diversify their existing portfolio of practical knowledge in the field.
Author: Andrei I. Ivanov
Publisher: Humana
ISBN: 9781493936014
Category : Science
Languages : en
Pages : 0
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Book Description
This volume provides a comprehensive collection of classical and cutting edge protocols and techniques to examine the normal development and physiological functions of the gastrointestinal system and to model the most common digestive diseases. The chapters focus on diverse research topics including ex vivo systems to study gastrointestinal development and functions, in vivo imaging of the gastrointestinal tract, isolation and characterization of intestinal immune cells, and animal models of gastrointestinal inflammation and cancer. The Gastrointestinal Physiology and Diseases: Methods and Protocols book targets wide audience of physiologists, cell and developmental biologists, immunologists, and physician-scientists working in the field of gastroenterology and beyond. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Highly practical and clearly written, Gastrointestinal Physiology and Diseases: Methods and Protocols will serve both seasoned researchers as well as newcomers to the field and will provide a unique resource and expert guidance to modern laboratory techniques developed for examining normal functions and diseases of the gastrointestinal tract.
Author: Alex Vasquez
Publisher: Createspace Independent Publishing Platform
ISBN: 9781530527113
Category :
Languages : en
Pages : 474
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Book Description
Refinements/edits made to text 20 Apr 2016: This work is the culmination of several thousand research publications combined with Dr Vasquez's many years of clinical experience and teaching graduate/doctorate-level students and clinicians worldwide. With radiographs, photos, acronyms, illustrations, flowcharts, and detailed-yet-simplifying explanations, Dr Vasquez makes it easier than ever for clinicians to grasp important concepts in integrative care and functional medicine and then translate the basic science and molecular biology into treatment plans that can be explained and used in "the real world" of clinical practice.This second volume is written for clinicians already conversant in Ch.1) Patient assessment, laboratory interpretation, risk management, hypothyroidism, hemochromatosis, Ch.2) Wellness, Personalized Lifestyle Medicine, Ch.3) Integrative pain management using nutrition, botanicals, and manipulative medicine, Ch.4) Functional Inflammology Protocol: Diet, Polydysbiosis/Infections, Viral infections, Nutritional immunomodulation, Mitochondrial dysfunction, mTOR, ERS-UPR, Orthoendocrinology, Xenobiotic detoxification.Contents: updated Chapter 5 from "Inflammation Mastery, 4th Ed"1) Hypertension...727, 2) Diabetes Mellitus...819, 3) Migraine & Headaches...863, 4) Fibromyalgia...901, 5) Allergic Inflammation...984, 6) Rheumatoid Arthritis...1019, 7) Psoriasis & Psoriatic Arthritis...1038, 8) Systemic Lupus Erythematosus...1053, 9) Scleroderma & Systemic Sclerosis...1074, 10) Vasculitic Diseases...1094, 11) Spondyloarthropathies & Reactive Arthritis...1108, 12) Sjögren Disease...1119, 13) Raynaud's Disorder...1127, 14) Clinical Notes on Behçet's Disease, Sarcoidosis, Dermatomyositis & Polymyositis...1131. The associated video tutorials and recorded live conference presentations further help students and clinicians "get it" via Dr Vasquez's effective teaching style which embraces complexity while always emphasizing clinical applicability and psychosocial context. The Inflammation Mastery & Functional Inflammology series of books and videos translates important concepts and nutritional/biomedical science into easy and practical clinical applications for the prevention and treatment of disorders of sustained inflammation, which Dr Vasquez describes as "patterns of metabolic disturbance and inflammatory dysfunction" existing in three sequential and overlapping categories: 1) metabolic inflammation, 2) allergic inflammation, 3) autoimmune inflammation. This book includes access to video presentations which introduce the origin and components of the Functional Inflammology Protocol and FINDSEX(r) acronym. Post-publication updates to this information and important social and clinical contextualization are made available in videos and online repositories (access provided in the book), and the e-newsletter available from ICHNFM.ORG. This textbook also provides access, via reprints or hyperlinks, to Dr Vasquez's published articles-paradigm-shifting perspectives published in Alternative Therapies in Health and Medicine (2004, 2014) and Nature Reviews Rheumatology (2016). Updated section on pain management allows students and clinicians to understand and apply manual, pharmacologic, nutritional/botanical medicine treatments for musculoskeletal pain, thereby providing better relief for patients and avoiding the hazards of NSAIDs, coxibs, steroids, opioids, immunosuppressants and biologics. Discounted grayscale printing; for full-color see ISBN 0990620441. The most recent publication from ICHNFM.ORG is "Functional Medicine Clinical Protocols for Inflammatory Disorders: Functional Inflammology, Vol 2" (2016; printed in color via ISBN 0990620441), which extends Vol 1 printed in 2014 in color as "Functional Inflammology" (ISBN 0990620409) and grayscale as "Inflammation Mastery" (ISBN 1500545945); also updated and published in color in 2016 as a single volume as "Inflammation Mastery, 4th Ed" (ISBN 0990620484).
Author: Juerg Hodler
Publisher: Springer Nature
ISBN: 303038490X
Category : Medical
Languages : en
Pages : 252
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Book Description
This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
Author: William Kemp
Publisher: McGraw Hill Professional
ISBN: 0071593799
Category : Medical
Languages : en
Pages : 458
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Book Description
Get the BIG PICTURE of Pathology - and focus on what you really need to know to score high on the course and board exam If you want a streamlined and definitive look at Pathology - one with just the right balance of information to give you the edge at exam time - turn to Pathology: The Big Picture. You'll find a succinct, user-friendly presentation especially designed to make even the most complex concept understandable in the shortest amount of study time possible. This perfect pictorial and textual overview of Pathology delivers: A “Big Picture” emphasis on what you must know verses “what's nice to know” Expert authorship by award-winning, active instructors Coverage of the full range of pathology topics - everything from cellular adaptations and injury to genetic disorders to inflammation to diseases of immunity Magnificent 4-color illustrations Numerous summary tables and figures for quick reference and rapid retention of even the most difficult topic Highlighted key concepts that underscore integral aspects of histology (key concepts are also listed in a table at the end of each chapter) USMLE-type questions, answers, and explanations to help you anticipate what you'll encounter on the exams And much more!
Author: Dr. Will Cole
Publisher: Penguin
ISBN: 0735220093
Category : Health & Fitness
Languages : en
Pages : 338
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Book Description
From the international bestselling author of Ketotarian comes a revolutionary new plan to discover the foods your unique body loves, hates, and needs to feel great. In Dr. Will Cole's game-changing new book, readers will discover how inflammation is at the core of most common health woes. What's more, it exists on a continuum: from mild symptoms such as weight gain and fatigue on one end, to hormone imbalance and autoimmune conditions on the other. How you feel is being influenced by every meal. Every food you eat is either feeding inflammation or fighting it. Because no one else is you, the foods that work well for someone else may not be right for your body. At heart, The Inflammation Spectrum is about learning to love your body enough to nourish it with delicious, healing foods. You'll find insightful quizzes and empowering advice to put you on a path toward food freedom and overall healing, once and for all.
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241549025
Category : Health & Fitness
Languages : en
Pages : 59
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Book Description
This guideline provides updated global, evidence-informed recommendations on the intake of free sugars to reduce the risk of NCDs in adults and children, with a particular focus on the prevention and control of unhealthy weight gain and dental caries. The recommendations in this guideline can be used by policy-makers and programme managers to assess current intake levels of free sugars in their countries relative to a benchmark. They can also be used to develop measures to decrease intake of free sugars, where necessary, through a range of public health interventions. Examples of such interventions and measures that are already being implemented by countries include food and nutrition labelling, consumer education, regulation of marketing of food and non-alcoholic beverages that are high in free sugars, and fiscal policies targeting foods and beverages that are high in free sugars. This guideline should be used in conjunction with other nutrient guidelines and dietary goals, in particular those related to fats and fatty acids (including saturated fatty acids and trans-fatty acids), to guide development of effective public health nutrition policies and programmes to promote a healthy diet.
Author: Vincent Pedre
Publisher: BenBella Books
ISBN: 163774255X
Category : Health & Fitness
Languages : en
Pages : 337
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Book Description
Take back control of your health—starting with the foundation for ultimate well-being: your gut and its microbiome. Use the GutSMART Quiz to evaluate your gut-related wellness and get a personalized 14-day meal plan and food lists based on your GutSMART Score. When you heal your gut, you heal your body. With The GutSMART Protocol’s two-week reset, it’s easier than ever to heal your gut to gain more energy, achieve easier weight loss, revitalize your health, and even boost your mood and mental performance. "America’s Gut Doctor" Vincent Pedre, MD, author of Happy Gut, updates us on the latest research about the gut, the microbiome, and the way our environment impacts our health, then translates the science into actionable and easy-to-apply advice for how to eat (and more!). Turbocharge your journey toward optimal gut (and total) wellness with proven tools, including: The GutSMART Quiz to determine your level of gut-related health dysfunction Categorized food lists for the three GutSMART Score types, making it easy to shop for your gut type 65 mouth-watering, gut-healing recipes from clinical nutritionist and chef Lee Holmes 14-day personalized meal plans customizable for any diet, from vegan to paleo Science-backed breathwork and meditation exercises to destress and further improve gut health Excellent health starts with the gut! The GutSMART Protocol is your first-of-its-kind personalized, food-based gut-healing plan for achieving a happy, healthy gut, in a happy body with a happy mind. The past several years have seen an explosion in gut microbiome research, and the powerful role the gut plays in whole-body health has never been more clear. What’s less clear is how to use that information day to day to actually improve the way you feel—that’s where this book comes in. Good health starts with the gut. The GutSMART Protocol is your food-based healing plan for achieving a happy gut.
