Solo

Solo PDF Author: C. Robert Kelly
Publisher: iUniverse
ISBN: 0595399592
Category : Biography & Autobiography
Languages : en
Pages : 528

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Book Description
In 1996, 60-year-old Bob Kelly temporarily lost the use of his legs. That disability was hard to bear for someone who had always been physically active. The following year, while looking for a way to use his upper body strength, he had an idea- to travel solo by kayak from Ottawa to the Atlantic. In 1998, after completing that journey, Kelly faced another loss with the death of Shirley, his beloved wife of 34 years. He decided to continue the kayak trip across Canada as a memorial to her. It was an odyssey that took him some 9,000 kilometres through the most challenging waterways of Canada. In Solo, Kelly tells how he overcame daunting obstacles, brutal weather, serious injuries and setbacks. The story ends on the historic Grand Portage, where Kelly faced the most gruelling test. "Long trips over water and portages are metaphors of life - the wind can be with you or a hurricane in your face. Bob's included physical and emotional obstacles greater than the whims of weather and geography. It spanned more than distance and time and was indeed the journey of an indomitable spirit." -Max Finklestein, author of Canoeing a Continent and Paddling the Boreal Forest.

Free Association

Free Association PDF Author: Steven Sidley
Publisher: Pan Macmillan South africa
ISBN: 1770105220
Category : Fiction
Languages : en
Pages : 335

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Book Description
Max Lurie’s navel-gazing podcast about his life has become an unexpected success. But its embellishments and inventions are starting to leak into his everyday life. As Max tries to navigate the grey areas between fact and fiction, things begin to spin out of control. He juggles real and imagined girlfriends, an illegally procured firearm, an unpredictable friendship with a homeless schizophrenic, his acerbic immigrant producer, his dying father, his famous childhood sweetheart, an unlikely romantic entanglement and his critical and growing audience. Can he keep all of these balls in the air and finally bring them safely to rest? This story takes a deep and satiric dive into the worlds we imagine for ourselves and the lives we actually live, particularly in a time when our real and digital personas intersect and merge in chaotic ways. Free Association casts a steely and comic eye on the great and small concerns of being human: the chances we take and miss, the pain of not fitting in, the fragility of the psyche, the unpredictability of love, the dull certainty of death, the importance of listening to others and the careening craziness of it all.

Indian Antiquary

Indian Antiquary PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 332

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Book Description


Upgrade Your Italian

Upgrade Your Italian PDF Author: Clelia Boscolo
Publisher: Routledge
ISBN: 1444119214
Category : Foreign Language Study
Languages : en
Pages : 225

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Book Description
Highly original and pragmatic approach Aimed at C and B grade students (i.e. the majority) Short, accessible and user-friendly

How to Think Like Leonardo da Vinci

How to Think Like Leonardo da Vinci PDF Author: Michael J. Gelb
Publisher: Dell
ISBN: 0307573524
Category : Self-Help
Languages : en
Pages : 336

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Book Description
This inspiring and inventive guide teaches readers how to develop their full potential by following the example of the greatest genius of all time, Leonardo da Vinci. Acclaimed author Michael J. Gelb, who has helped thousands of people expand their minds to accomplish more than they ever thought possible, shows you how. Drawing on Da Vinci's notebooks, inventions, and legendary works of art, Gelb introduces Seven Da Vincian Principles—the essential elements of genius—from curiosità, the insatiably curious approach to life to connessione, the appreciation for the interconnectedness of all things. With Da Vinci as your inspiration, you will discover an exhilarating new way of thinking. And step-by-step, through exercises and provocative lessons, you will harness the power—and awesome wonder—of your own genius, mastering such life-changing abilities as: •Problem solving •Creative thinking •Self-expression •Enjoying the world around you •Goal setting and life balance •Harmonizing body and mind Drawing on Da Vinci's notebooks, inventions, and legendary works of art, acclaimed author Michael J. Gelb, introduces seven Da Vincian principles, the essential elements of genius, from curiosita, the insatiably curious approach to life, to connessione, the appreciation for the interconnectedness of all things. With Da Vinci as their inspiration, readers will discover an exhilarating new way of thinking. Step-by-step, through exercises and provocative lessons, anyone can harness the power and awesome wonder of their own genius, mastering such life-changing skills as problem solving, creative thinking, self-expression, goal setting and life balance, and harmonizing body and mind.

Catalogue of Music in the Library of Christ Church, Oxford

Catalogue of Music in the Library of Christ Church, Oxford PDF Author: Christ Church (University of Oxford). Library
Publisher:
ISBN:
Category : Music
Languages : en
Pages : 224

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Book Description


Catalogue of Music in the Library of Christ Church, Oxford

Catalogue of Music in the Library of Christ Church, Oxford PDF Author: University of Oxford. Christ Church College. Library
Publisher:
ISBN:
Category : Music
Languages : en
Pages : 224

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Book Description


Matched for Eternity

Matched for Eternity PDF Author: Carmen Lin
Publisher: WestBow Press
ISBN: 1512782327
Category : Biography & Autobiography
Languages : en
Pages : 465

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Book Description
Have you struggled in your Christian faith, thinking the Bible is too hard to understand and Gods will too elusive to know? Or have you thought there are no more miracles today and God does not care about you? Or do you think that in our day and age, the Bible is no longer relevant? Do you think life is too hard, your marriage is hopeless, nobody understands, and you want to give up? Do you think divorce will solve your marriage problems? Do you think you have suffered too much? Have you blamed your parents or the society for all the troubles in your life? Have you dabbed in occult practice thinking it is fun? In this book, Carmen shares the inspirational story of her marriage to her husband and their ministry. Their story provides insight and answers to these questions and more.

Mental Illness in the Family

Mental Illness in the Family PDF Author: Fred Goodwin
Publisher: Lichtenstein Creative Media
ISBN: 1888064749
Category : Health & Fitness
Languages : en
Pages : 22

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Book Description


LuxR Solos Are Becoming Major Players in Cell-Cell Communication in Bacteria

LuxR Solos Are Becoming Major Players in Cell-Cell Communication in Bacteria PDF Author: Vittorio Venturi
Publisher: Frontiers Media SA
ISBN: 2889199177
Category : Biology (General)
Languages : en
Pages : 122

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Book Description
The most common quorum sensing (QS) system in Gram-negative bacteria occurs via N-acyl homoserine lactone (AHLs) signals. An archetypical system consists of a LuxI-family protein synthesizing the AHL signal which binds at quorum concentrations to the cognate LuxR-family transcription factors which then control gene expression by binding to specific sequences in target gene promoters. QS LuxR-family proteins are approximately 250 amino acids long and made up of two domains; at the N-terminus there is an autoinducer-binding domain whereas the C-terminus contains a DNA-binding helix-turn-helix (HTH) domain. QS LuxRs display surprisingly low similarities (18-25%) even if they respond to structurally similar AHLs. 95% of LuxRs share 9 highly conserved amino acid residues; six of these are hydrophobic or aromatic and form the cavity of the AHL-binding domain and the remaining three are in the HTH domain. With only very few exceptions, the luxI/R cognate genes of AHL QS systems are located adjacent to each other. The sequencing of many bacterial genomes has revealed that many proteobacteria also possess LuxRs that do not have a cognate LuxI protein associated with them. These LuxRs have been called orphans and more recently solos. LuxR solos are widespread in proteobacterial species that possess a canonical complete AHL QS system as well as in species that do not. In many cases more than one LuxR solo is present in a bacterial genome. Scientists are beginning to investigate these solos. Are solos responding to AHL signals? If present in a bacterium which possesses a canonical AHL QS system are solos an integral part of the regulatory circuit? Are LuxR solos eavesdropping on AHLs produced by neighboring bacteria? Have they evolved to respond to different signals instead of AHLs, and are these signals endogenously produced or exogenously provided? Are they involved in interkingdom signaling by responding to eukaryotic signals? Recent studies have revealed that LuxR solos are involved in several mechanisms of cell-cell communication in bacteria implicating them in bacterial intraspecies and interspecies communication as well as in interkingdom signaling by responding to molecules produced by eukaryotes. LuxR solos are likely to become major players in signaling since they are widespread among proteobacterial genomes and because initial studies highlight their different roles in bacterial communication. This Research Topic allows scientists studying or interested in LuxR solos to report their data and/or express their hypotheses and thoughts on this important and currently understudied family of signaling proteins.

Singuliers 19

Singuliers 19 PDF Author: Paul Melchior
Publisher: Pascal Maurice éditeur / Singuliers magazine
ISBN:
Category : Biography & Autobiography
Languages : en
Pages : 419

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Book Description
24 postscripts for the addendum to the 1st edition of the book "Russian scams during Ukraine war on a dating website" entitled "Death of pseudo Ukrainian (Russian scammers during war)" complement of sequences from "No-Shows No-Film for Ukraine" ; full version in this Supplement to n° 19 "Singuliers" magazine – ISSN 0992-2881.