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Author: Judith Raimbourg
Publisher:
ISBN:
Category :
Languages : fr
Pages : 98
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Book Description
La prise en charge du cancer du sein métastatique a évolué ces 20 dernières années avec le développement de nouveaux traitements de chimiothérapie dont l'impact sur la survie n'est pas clairement établi. Nous avons analysé l'impact de la 1ère ligne de chimiothérapie sur la survie au cours du temps en comparant deux populations de patientes suivies pour un cancer du sein métastatique à l'Institut de Cancérologie de l'Ouest entre 1992 et 1995 (période I n=185) et entre 2001 et 2004 (période II n=196). Il n'y a pas de différence significative en survie globale entre les deux périodes (26 vs 29 mois p=0.12). Il existe une augmentation significative de la survie sans progression au cours du temps pour la population globale (10.2 vs 12 mois p=0.08) et dans le sous-groupe des patientes traitées par une 1ère ligne de chimiothérapie (8.4 vs 11.8 mois p=0.022). Le délai sans rechute > 24 mois, la positivité des récepteurs aux œstrogènes et la période II sont des facteurs pronostiques favorables sur la survie globale. Les nouveaux agents de chimiothérapie améliorent la survie sans progression mais ne semblent pas améliorer la survie globale.
Author: Judith Raimbourg
Publisher:
ISBN:
Category :
Languages : fr
Pages : 98
Get Book Here
Book Description
La prise en charge du cancer du sein métastatique a évolué ces 20 dernières années avec le développement de nouveaux traitements de chimiothérapie dont l'impact sur la survie n'est pas clairement établi. Nous avons analysé l'impact de la 1ère ligne de chimiothérapie sur la survie au cours du temps en comparant deux populations de patientes suivies pour un cancer du sein métastatique à l'Institut de Cancérologie de l'Ouest entre 1992 et 1995 (période I n=185) et entre 2001 et 2004 (période II n=196). Il n'y a pas de différence significative en survie globale entre les deux périodes (26 vs 29 mois p=0.12). Il existe une augmentation significative de la survie sans progression au cours du temps pour la population globale (10.2 vs 12 mois p=0.08) et dans le sous-groupe des patientes traitées par une 1ère ligne de chimiothérapie (8.4 vs 11.8 mois p=0.022). Le délai sans rechute > 24 mois, la positivité des récepteurs aux œstrogènes et la période II sont des facteurs pronostiques favorables sur la survie globale. Les nouveaux agents de chimiothérapie améliorent la survie sans progression mais ne semblent pas améliorer la survie globale.
Author: Monica Morrow
Publisher: PMPH-USA
ISBN: 9781550092608
Category : Breast
Languages : en
Pages : 328
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Book Description
Managing Breast Cancer Risk is a single source for information needed by primary care physicians, nurses, gynecologists, as well as oncologic specialists who deal with women who are concerned about breast cancer. Its purpose is to bring together a multidisciplinary group of experts to address breast cancer risk in a clinically meaningful way. Chapters providing detailed information on individual risk factors are accompanied by a discussion of models, which integrate multiple factors for a more complete assessment of risk. Traditional strategies for risk management, including surveillance and prophylactic surgery, are reviewed, and the data on newer techniques such as ductal lavage and screening with magnetic resonance is presented. The rational for chemoprevention with selective estrogen receptor modulators (SERMS) is discussed, and the evidence for tamoxifen as a chemopreventative is updated. The potential for chemoprevention with newer SERMS and the aromatase inhibitors is reviewed. Finally, the critical (and often ignored) areas of quality of life and symptom management are addressed.
Author: Gw Sledge
Publisher: Clinical Pub
ISBN: 9781846920660
Category : Breast
Languages : en
Pages : 0
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Book Description
This new volume updates the reader on selected areas of targeted therapy in breast cancer, with special emphasis on chemoprevention strategies, drug resistance, biomarkers, combination chemotherapy, angiogenesis inhibition and pharmacogenomics in the context of clinical efficacy. This selected review of targeted therapies will guide the reader on effective treatment as part of an integrated programme of patient management.
Author: Leszek Szablewski
Publisher: BoD – Books on Demand
ISBN: 178985525X
Category : Medical
Languages : en
Pages : 140
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Book Description
The main source of energy for the body is glucose. Its low blood concentrations can cause seizures, loss of consciousness and death. Long lasting high glucose levels can cause blindness, renal failure, cardiac and peripheral vascular disease, and neuropathy. Blood glucose concentrations need to be maintained within narrow limits. The process of maintaining blood glucose at a steady state is called glucose homeostasis. This is achieved through a balance of the rate of consumption of dietary carbohydrates, utilization of glucose by peripheral tissues, and the loss of glucose through the kidney tubule. The liver and kidney also play a role in glucose homeostasis. This book aims to provide an overview of blood glucose levels in health and diseases.
Author: Monica Castiglione
Publisher: Springer Science & Business Media
ISBN: 0387751157
Category : Medical
Languages : en
Pages : 483
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Book Description
Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.
Author: Richard J. Wassersug, PhD
Publisher: Springer Publishing Company
ISBN: 0826183956
Category : Health & Fitness
Languages : en
Pages : 247
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Book Description
Praise for Androgen Deprivation Therapy: "To my knowledge [this] is the only book written in plain language (no medical jargon) explaining what’s happening during ADT, and detailing how to limit and often solve most associated side effects. It should be read by every man undergoing ADT, as well as family members and also healthcare providers. They will find all the details they need to get the most from this treatment..." Prof. N. Mottet, MD, PhD, Urologist, Medical Oncologist, Head of the Prostate Cancer Guidelines panel of the European Association of Urology Androgen Deprivation Therapy is the only guide written exclusively about the side effects of hormone therapy. The authors have collaborated with the European Association of Urology to produce this specially revised new edition to serve men affected by ADT across the globe. This comprehensive workbook for prostate cancer patients and their loved ones is filled with practical advice from experts in the field. The book covers a wealth of strategies to help men cope with ADT and maintain a good quality of life while on this treatment. It is not only an informational manual, but a guide for both patients and partners about ways to make changes in their lives that can keep them healthy and positive when the patient is on ADT. New to this Edition: Updates on the physical side effects of ADT and management strategies Expanded information on exercise and nutrition for men diagnosed with prostate cancer Updates on the primary drugs used to treat prostate cancer and extensive drug tables with common brand names worldwide Revisions throughout based on critical feedback from international medical experts in the field of prostate cancer and related disciplines Exercises, activities, worksheets, and other tools to promote discussion and inspire behavioural changes that can reduce the burden of ADT Officially endorsed by the European Association of Urology
Author: Alan D. Lopez
Publisher: World Bank Publications
ISBN: 0821362631
Category : Medical
Languages : en
Pages : 511
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Book Description
Strategic health planning, the cornerstone of initiatives designed to achieve health improvement goals around the world, requires an understanding of the comparative burden of diseases and injuries, their corresponding risk factors and the likely effects of invervention options. The Global Burden of Disease framework, originally published in 1990, has been widely adopted as the preferred method for health accounting and has become the standard to guide the setting of health research priorities. This publication sets out an updated assessment of the situation, with an analysis of trends observed since 1990 and a chapter on the sensitivity of GBD estimates to various sources of uncertainty in methods and data.
Author: Daniel Vanel
Publisher: Springer Science & Business Media
ISBN: 3642875564
Category : Medical
Languages : en
Pages : 390
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Book Description
As with the introduction of x -ray computed tomography, much of the initial development of magnetic resonance applications tended to focus on the central nervous system. The development of magnetic resonance imaging applications to other organ systems such as the chest, abdomen, pelvis and extremities has lagged somewhat behind, awaiting technical improvements, and a broader user base. The past two years have seen a marked increase in imaging applications throughout the body, most notably the musculoskeletal system. It is in this regard, that MRI of the Body is a welcome arrival as a text which describes both basic principles of magnetic resonance ima ging and surveys the current status of magnetic resonance imaging applications throughout the body. The volume is concise, focused, clinically oriented, and abun dantly illustrated. In each organ system, the appropriate technical approach is discussed, the normal anatomic features are reviewed, and the range of pathologic appearances which may be encountered are described. The authors of the chapters provide a balanced overview of MR applications and describe both present limitations and future potential of magnetic resonance imaging applications in the organ system described.
Author: Laszlo Muszbek
Publisher: CRC Press
ISBN: 1000013308
Category : Medical
Languages : en
Pages : 278
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Book Description
First Published in 1987: The book is to give insight into the multisided relationship of hemostatic systems and malignancies and to help biomedical scientists and practicing clinicians obtain a better understanding of cancer research.
Author: Bita Esmaeli
Publisher: Springer Science & Business Media
ISBN: 1441903747
Category : Medical
Languages : en
Pages : 483
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Book Description
This book highlights the unique aspects of oncologic ophthalmology as a medical and surgical discipline practiced at a comprehensive cancer center. Multi-disciplinary management of ocular, orbital and adnexal cancers are highlighted using simple and tried-and-true algorithms. In addition, ocular problems caused as a direct result of cancer treatment are reviewed using illustrative photographs and case presentations. The content is provided by full-time ophthalmology faculty and fellows at M. D. Anderson Cancer Center. Experts in complementary disciplines such as ophthalmic pathology, dermatopathology, radiation oncology, radiology, and other surgical subspecialties have brought their unique perspective to each chapter. The book is abundant with clinical photographs as well as interesting case presentations that will help the clinician correctly diagnose cancers of the orbit, eye, and adnexal structures, initiate appropriate management, as well as recognize and treat common ocular complications of cancer therapy.
