Cumulated Index Medicus PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Cumulated Index Medicus PDF full book. Access full book title Cumulated Index Medicus by . Download full books in PDF and EPUB format.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1860
Get Book Here
Book Description
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1860
Get Book Here
Book Description
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 854
Get Book Here
Book Description
Author: Robert O J Weinzierl
Publisher: World Scientific
ISBN: 1783262257
Category : Science
Languages : en
Pages : 437
Get Book Here
Book Description
A detailed knowledge of the mechanisms underlying the transcriptional control of gene expression is of fundamental importance to many areas of contemporary biomedical research, ranging from understanding basic issues (such as control of embryonic development) to practical applications in industry and medicine. Although elementary concepts of gene expression are described in all general molecular biology textbooks, the depth of coverage is often rather limited and recent discoveries are sometimes not adequately taken into consideration.This book presents much of the current thinking concerning molecular mechanisms of transcriptional control in a form easily accessible to undergraduates with an understanding of basic molecular biology concepts. It contains detailed information about the various pro- and eukaryotic transcriptional machineries that has recently become available through the combined efforts of geneticists, biochemists and structural biologists. The book will thus not only serve as an undergraduate text but also offer something new and interesting to more advanced readers and professional scientists who want to keep up to date with rapid advances in this field.
Author: Erica A. Golemis
Publisher: CSHL Press
ISBN: 0879697237
Category : Interactions protéine-protéine - Manuels de laboratoire
Languages : en
Pages : 954
Get Book Here
Book Description
Reflecting the various advances in the field, this book provides comprehensive coverage of protein-protein interactions. It presents a collection of the technical and theoretical issues involved in the study of protein associations, including biophysical approaches. It also offers a collection of computational methods for analyzing interactions.
Author:
Publisher:
ISBN:
Category : Nucleic acids
Languages : en
Pages : 1158
Get Book Here
Book Description
Author: Gregg L. Semenza
Publisher: Oxford Monographs on Medical G
ISBN: 9780195112399
Category : Health & Fitness
Languages : en
Pages : 396
Get Book Here
Book Description
Several general principles have emerged from the study of human transcription factors. First, germline mutations in genes encoding transcription factors result in malformation syndromes in which the development of multiple body structures is affected. Second, somatic mutations involving many of the same genes contribute to tumorigenesis. Third, transcriptional regulatory mechanisms demonstrate remarkable evolutionary conservation. Fourth, prenatal development and postnatal physiology are unified by the demonstration that a single transription factor can control the proliferation of progenitor cells during development and the expression within the differentiated cells of gene products that participate in specific physiologic responses. Transcription Factors and Human Disease presents the basic science of transcriptional regulation and then describes inherited human diseases attributable to mutations in DNA sequences encoding transcription factors or their cognate binding sites. The involvement of transcription factors in somatic cell genetic diseases (cancer) and epigenetic disease (teratogenesis) is briefly discussed. The effect of specific mutations on transcription factor activity and the relationship between transcriptional dysregulation, dominant or recessive inheritance patterns, and disease pathogenesis are also explored. This book thus provides a direct connection between molecular defects in transcriptional regulation and human pathophysiology.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 2324
Get Book Here
Book Description
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author: National Cancer Institute (U.S.). Division of Basic Sciences
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 476
Get Book Here
Book Description
Author: Henri Heslot
Publisher: CRC Press
ISBN: 135108318X
Category : Technology & Engineering
Languages : en
Pages : 405
Get Book Here
Book Description
Molecular Biology and Genetic Engineering of Yeasts presents a comprehensive examination of how yeasts are used in genetic engineering. The book discusses baker's yeast, in addition to a number of unconventional yeasts being used in an increasing number of studies. 175 figures help illustrate the information presented. Topics discussed include yeast transformation, yeast plasmids, protein localization and processing in yeast, protein secretion, various aspects of Saccharomyces cerevisiae, and heterologous expression and secretion.
Author: Shiro Iuchi
Publisher: Springer Science & Business Media
ISBN: 0387274219
Category : Science
Languages : en
Pages : 291
Get Book Here
Book Description
In the early 1980s, a few scientists started working on a Xenopus transcription factor, TFIIIA. They soon discovered a novel domain associated with zinc, and named this domain "zinc finger. " Th e number of proteins with similar zinc fingers grew quickly and these proteins are now called C2H2, Cys2His2 or classical zinc finger proteins. To date, about 24,000 C2H2 zinc finger proteins have been recognized. Approximately 700 human genes, or more than 2% of the genome, have been estimated to encode C2H2 finger proteins. From the beginning these proteins were thought to be numerous, but no one could have predicted such a huge number. Perhaps thousands of scientists are now working on C2H2 zinc finger proteins fi-om variou s viewpoints. This field is a good example of how a new science begins with the insight of a few scientists and how it develops by efforts of numerous independent scientists, in contrast to a policy-driven scientific project, such as the Human Genome Project, with goals clearly set at its inception and with work performed by a huge collaboration throughout the world. As more zinc finger proteins were discovered, several subfamilies, such as C2C2, CCHC, CCCH, LIM, RING, TAZ, and FYVE emerged, increasing our understanding of zinc fingers. The knowledge was overwhelming. Moreover, scientists began defining the term "zinc finger" differently and using various names for identical zinc fingers. These complications may explain why no single comprehensive resource of zinc finger proteins was available before this publication.
