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Author: Pyotr M Kruglyakov
Publisher: Elsevier
ISBN: 0080534333
Category : Science
Languages : en
Pages : 405
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Book Description
This book considers the different concepts of hydrophile-lipophile balance (HLB) of surfactants and solid particles and the main physicochemical properties of surfactant and solid interfaces which are used to definite the hydrophile-lipophile balance. The book comprehensively analyses all interfacial and bulk properties of surfactants used for the determination of HLB (such as interfacial tension, distribution coefficient, adsorption, surface pressure, surfactants solubility, structure characteristics, distribution between heteropolar phases, micellar formation, chromatographic characteristics, phase separation in emulsions, phase inversion temperature, formation of three phase systems).The central point of the book is the energetic interpretation of the balance, i.e. the hydrophile-lipophile ratio. At the same time the HLB-number systems of Griffin and Davies and other independant methods of the hydrophile-lipophile balance definitions are discussed: PIT, polarity indexes, surfactant affinity difference etc. The possibility of application of the different characteristics of the hydrophile-lipophile balance as a criterion of phase inversion in emulsions and microemulsion systems water-oil-surfactant are considered.For the first time the different methods of the hydrophile-lilophile balance definition for solid particles in compact and dispersed form are suggested by the author. The use of hydrophile-lipophile characteristics of solid particles as a criterion of phase inversion in emulsion stabilisation and for other applications is discussed.
Author: Pyotr M Kruglyakov
Publisher: Elsevier
ISBN: 0080534333
Category : Science
Languages : en
Pages : 405
Get Book Here
Book Description
This book considers the different concepts of hydrophile-lipophile balance (HLB) of surfactants and solid particles and the main physicochemical properties of surfactant and solid interfaces which are used to definite the hydrophile-lipophile balance. The book comprehensively analyses all interfacial and bulk properties of surfactants used for the determination of HLB (such as interfacial tension, distribution coefficient, adsorption, surface pressure, surfactants solubility, structure characteristics, distribution between heteropolar phases, micellar formation, chromatographic characteristics, phase separation in emulsions, phase inversion temperature, formation of three phase systems).The central point of the book is the energetic interpretation of the balance, i.e. the hydrophile-lipophile ratio. At the same time the HLB-number systems of Griffin and Davies and other independant methods of the hydrophile-lipophile balance definitions are discussed: PIT, polarity indexes, surfactant affinity difference etc. The possibility of application of the different characteristics of the hydrophile-lipophile balance as a criterion of phase inversion in emulsions and microemulsion systems water-oil-surfactant are considered.For the first time the different methods of the hydrophile-lilophile balance definition for solid particles in compact and dispersed form are suggested by the author. The use of hydrophile-lipophile characteristics of solid particles as a criterion of phase inversion in emulsion stabilisation and for other applications is discussed.
Author: Shelley Chambers Fox
Publisher: Pharmaceutical Press
ISBN: 0857110705
Category : Medical
Languages : en
Pages : 561
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Book Description
Remington Education: Pharmaceutics covers the basic principles of pharmaceutics, from dosage forms to drug delivery and targeting. It addresses all the principles covered in an introductory pharmacy course. As well as offering a summary of key information in pharmaceutics, it offers numerous case studies and MCQs for self assessment.
Author: Kevin M.G. Taylor
Publisher: Elsevier Health Sciences
ISBN: 0702053937
Category : Medical
Languages : en
Pages : 909
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Book Description
Pharmaceutics is one of the most diverse subject areas in all of pharmaceutical science. In brief, it is concerned with the scientific and technological aspects of the design and manufacture of dosage forms or medicines. An understanding of pharmaceutics is therefore vital for all pharmacists and those pharmaceutical scientists who are involved with converting a drug or a potential drug into a medicine that can be delivered safely, effectively and conveniently to the patient. Now in its fourth edition, this best-selling textbook in pharmaceutics has been brought completely up to date to reflect the rapid advances in delivery methodologies by eye and injection, advances in drug formulations and delivery methods for special groups (such as children and the elderly), nanomedicine, and pharmacognosy. At the same time the editors have striven to maintain the accessibility of the text for students of pharmacy, preserving the balance between being a suitably pitched introductory text and a clear reflection of the state of the art. New to this edition New editor: Kevin Taylor, Professor of Clinical Pharmaceutics, School of Pharmacy, University of London. Twenty-two new contributors. Six new chapters covering parenteral and ocular delivery; design and administration of medicines for the children and elderly; the latest in plant medicines; nanotechnology and nanomedicines, and the delivery of biopharmaceuticals. Thoroughly revised and updated throughout. provides a logical, comprehensive account of drug design and manufacture includes the science of formulation and drug delivery designed and written for newcomers to the design of dosage forms New to this edition New editor: Kevin Taylor, Professor of Clinical Pharmaceutics, School of Pharmacy, University of London. Twenty-two new contributors. Six new chapters covering parenteral and ocular delivery; design and administration of medicines for the children and elderly; the latest in plant medicines; nanotechnology and nanomedicines, and the delivery of biopharmaceuticals. Thoroughly revised and updated throughout.
Author: Bob Aveyard
Publisher: Oxford University Press
ISBN: 0192563750
Category : Science
Languages : en
Pages : 400
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Book Description
Surfactants... today you have probably eaten some, or rubbed others on your body. Plants, animals (including you) and microorganisms make them, and many everyday products (e.g. detergents, cosmetics, foodstuffs) contain them. Surfactant molecules have one part which is soluble in water and another which is not. This gives surfactant molecules two valuable properties: 1) they adsorb at surfaces (e.g. of an oil droplet in water), and 2) they stick together (aggregate) in water. The aggregates (micelles) are able to dissolve materials not soluble in water alone, and adsorbed surfactant layers, at the surfaces of particles or (say) oil droplets in water, stop the particles or drops sticking together. This is why stable emulsions such as milk do not separate into layers. This book treats the basic physical chemistry and physics underlying the behaviour of surfactant systems. In this book, you will first learn about some background material including hydrophobic hydration, interfacial tension and capillarity (Section I). Discussion of surfactant adsorption at liquid/fluid and solid/liquid interfaces is given in Section II, and includes thermodynamics of adsorption, dynamic and rheological aspects of liquid interfaces and the direct characterisation of surfactant monolayers. In Section III, a description is given of surfactant aggregation to give micelles, lyotropic liquid crystals, microemulsions and Winsor systems. There follows a discussion of surface forces and the way they confer stability on lyophobic colloids and thin liquid films (Section IV). Various dispersions stabilised by adsorbed surfactant or polymer (including solid in liquid dispersions, emulsions and foams) are considered in Section V. The wetting of solids and liquids is explored in Section VI. Like surfactants, small solid particles can adsorb at liquid/fluid interfaces, form monolayers and stabilise emulsions and foams. Such behaviour is covered in Section VII. It is assumed the reader has a knowledge of undergraduate physical chemistry, particularly chemical thermodynamics, and of simple physics. Mathematics (elementary algebra and calculus) is kept at a level consistent with the straightforward derivation of many of the equations presented.
Author: Ram I. Mahato
Publisher: CRC Press
ISBN: 1482253690
Category : Medical
Languages : en
Pages : 667
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Book Description
Completely revised and updated, this third edition of Pharmaceutical Dosage Forms and Drug Delivery elucidates the basic principles of pharmaceutics, biopharmaceutics, dosage form design, and drug delivery – including emerging new biotechnology-based treatment modalities. The authors integrate aspects of physical pharmacy, chemistry, biology, and biopharmaceutics into drug delivery. This book highlights the increased attention that the recent spectacular advances in gene therapy and nanotechnology have brought to dosage form design and drug delivery. With the expiration of older patents and generic competition, the biopharmaceutical industry is evolving faster than ever. Apart from revising and updating existing chapters on the basic principles, this edition highlights the emerging emphasis on drug discovery, antibodies and antibody-drug conjugates as therapeutic moieties, individualized medicine including patient stratification strategies, targeted drug delivery, and the increasing role of modeling and simulation. Although there are numerous books on pharmaceutics and dosage forms, most cover different areas of the discipline and do not provide an integrated approach. The integrated approach of this book not only provides a singular perspective of the overall field, but also supplies a unified source of information for students, instructors and professionals, saving their time and money.
Author: Robert P. Shrewsbury
Publisher: Morton Publishing Company
ISBN: 1617314196
Category : Medical
Languages : en
Pages : 465
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Book Description
Applied Pharmaceutics in Contemporary Compounding, Third Edition is designed to convey a fundamental understanding of the principles and practices involved in both the development and the production of compounded dosage forms by applying pharmaceutical principles.
Author: Shan Jiang
Publisher: Royal Society of Chemistry
ISBN: 1849735107
Category : Science
Languages : en
Pages : 313
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Book Description
Named after the two-faced roman god, Janus particles have gained much attention due to their potential in a variety of applications, including drug delivery. This is the first book devoted to Janus particles and covers their methods of synthesis, how these particles self-assemble, and their possible uses. By following the line of synthesis, self-assembly and applications, the book not only covers the fundamental and applied aspects, but it goes beyond a simple summary and offers a logistic way of selecting the proper synthetic route for Janus particles for certain applications. Written by pioneering experts in the field, the book introduces the Janus concept to those new to the topic and highlights the most recent research progress on the topic for those active in the field and catalyze new ideas.
Author: To Ngai
Publisher: Royal Society of Chemistry
ISBN: 1782620141
Category : Science
Languages : en
Pages : 337
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Book Description
There has been much scientific interest in the behaviour of colloidal particles at liquid interfaces. From a research aspect they provide model systems for fundamental studies of condensed matter physics. From a commercial aspect they provide applications for making new materials in the cosmetics, food and paint industries. In many cases of colloidal particles at interfaces, the mechanism of particle interactions is still unknown. Particle-Stabilized Emulsions and Colloids looks at recent studies on the behaviour of particles at liquid interfaces. The book first introduces the basic concepts and principles of colloidal particles at liquid-liquid interfaces including the interactions and conformations. The book then discusses the latest advances in emulsions and bicontinuous emulsions stabilized by both solid and soft particles and finally the book covers applications in food science and oil extraction. With contributions from leading experts in these fields, this book will provide a background to academic researchers, engineers, and graduate students in chemistry, physics and materials science. The commercial aspects will also be of interest to those working in the cosmetics, food and oil industry.
Author: Dr. K.L. Senthilkumar
Publisher: Thakur Publication Private Limited
ISBN: 9388809882
Category : Education
Languages : en
Pages : 279
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Book Description
Buy E-Book of Industrial Pharmacy-I (English Edition) Book For B.Pharm 5th Semester of U.P. State Universities
Author: Laurier Lincoln Schramm
Publisher: Cambridge University Press
ISBN: 0521640679
Category : Science
Languages : en
Pages : 633
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Book Description
This 2000 book provides an introduction to the nature, occurrence, physical properties, propagation, and uses of surfactants in the petroleum industry.
