Humanizing Prostate Cancer PDF Download
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Author: Roger E. Schultz
Publisher: Brandylane Publishers Inc
ISBN: 1883911346
Category : Health & Fitness
Languages : en
Pages : 90
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Book Description
Author: Roger E. Schultz
Publisher: Brandylane Publishers Inc
ISBN: 1883911346
Category : Health & Fitness
Languages : en
Pages : 90
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Book Description
Author: National Cancer Institute (U.S.). Prostate Cancer Progress Review Group
Publisher:
ISBN:
Category : Prostate
Languages : en
Pages : 142
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Book Description
Author: Richard G. Pestell
Publisher: Springer Science & Business Media
ISBN: 1603270795
Category : Medical
Languages : en
Pages : 462
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Book Description
Award winning authors present a comprehensive review of new perspectives in prostate cancer research and open up new directions in the clinical management of prostate cancer. The authors focus on the biology, genetics, molecular signaling networks in the disease process, and recent advances in the treatment of prostate cancer. This state-of-the-art title provides key insights into cutting edge advances in prostate cancer and into future, novel treatment strategies.
Author: Chawnshang Chang
Publisher: World Scientific
ISBN: 9814481610
Category : Medical
Languages : en
Pages : 450
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Book Description
Prostate cancer is the second leading cause of death in men and its progression is highly dependent on androgens and androgen receptors. However, even with treatment, eventually most prostate cancers progress. Studies of the mechanisms behind this progression leads to advances in treatments for androgen-related diseases. Our book discusses recent prostate cancer research, which includes the following topics: immunotherapy and chemotherapy; radiation, gene, hormonal, and androgen ablation therapies; basic mechanisms behind prostate cancer growth; how mechanisms can be used to treat prostate cancer; and research in newly developed mouse model systems.This book should be of interest as both a study guide and research reference to students, basic scientists, and clinicians.
Author: Gerhardt Attard
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Kenneth J. Souza
Publisher: Xlibris Corporation
ISBN: 1453502262
Category : Health & Fitness
Languages : en
Pages : 114
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Book Description
Kenneth J. (Ken) Souza is a natural born story teller with a gift to make people laugh and feel good about being alive. His humor and sensitivity come alive in his writing, during his motivational speaking, or talking one-on-one over coffee. Ken was born in Alameda, California in 1948 and raised in San Leandro and Oakland, California. Ken’s occupation as a Teamster for 37 years flavored his ability to find the right words to express the dimension of his experiences in life. Ken served both as a truck driver and then as an officer for Teamsters Local 432 in Oakland. This is Ken’s first book.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 70
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Book Description
Androgen receptor (AR) is a critical component in prostrate oncogenesis. AR alleles varying in length of the Nterminal glutamine (Q) tract carry distinct disease risks. Mutation of AR in tumors may influence androgen independence and resistance to treatment. Difficulties studying cancer initiation and progression are partly overcome with transgenic mouse tumor models. However, the mouse AR N-terminus differs significantly from human.
Author: Kenichiro Ishii
Publisher: MDPI
ISBN: 3039360345
Category : Medical
Languages : en
Pages : 184
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Book Description
The number of males diagnosed with prostate cancer (PCa) is increasing all over the world. Most patients with early-stage PCa can be treated with appropriate therapy, such as radical prostatectomy or irradiation. On the other hand, androgen deprivation therapy (ADT) is the standard systemic therapy given to patients with advanced PCa. ADT induces temporary remission, but the majority of patients (approximately 60%) eventually progress to castration-resistant prostate cancer (CRPC), which is associated with a high mortality rate. Generally, well-differentiated PCa cells are androgen dependent, i.e., androgen receptor (AR) signalling regulates cell cycle and differentiation. The loss of AR signalling after ADT triggers androgen-independent outgrowth, generating poorly differentiated, uncontrollable PCa cells. Once PCa cells lose their sensitivity to ADT, effective therapies are limited. In the last few years, however, several new options for the treatment of CRPC have been approved, e.g., the CYP17 inhibitor, the AR antagonist, and the taxane. Despite this progress in the development of new drugs, there is a high medical need for optimizing the sequence and combination of approved drugs. Thus, the identification of predictive biomarkers may help in the context of personalized medicine to guide treatment decisions, improve clinical outcomes, and prevent unnecessary side effects. In this Special Issue Book, we focused on the cytobiology of human PCa cells and its clinical applications to develop a major step towards personalized medicine matched to the individual needs of patients with early-stage and advanced PCa and CRPC. We hope that this Special Issue Book attracts the attention of readers with expertise and interest in the cytobiology of PCa cells.
Author: Leland W. K. Chung
Publisher: Springer Science & Business Media
ISBN: 1597452246
Category : Medical
Languages : en
Pages : 512
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Book Description
Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, reviews new, valuable approaches to the treatment of prostate cancer in men. The latest edition contains new material on molecular imaging, new treatments for prostate cancer, molecular targets, cell signaling pathways, bioinformatics, and pathogenomics. The book details the latest innovations and advances in prostate cancer and may be used as a rapid reference text for readers. The volume profiles the latest advances in cancer research and treatment and includes profound studies in prostate stem cells, cancer-host interactions, hedgehog signaling in development and cancer, cholesterol and cell signaling, gene therapy for advanced prostate cancer, and noninvasive strategies such as molecular imaging to visualize gene expression. This new edition also investigates expression profiling and somatic alterations in prostate cancer progression and linkage studies of prostate cancer families to identify susceptibility genes. The issues of racial differences in prostate cancer mortality, radiotherapy for the treatment of locally advanced prostate cancer, recombinant antibody candidates for treatment, taxane-based chemotherapy, lethal phenotypes, and novel and efficient translation clinical trials are also presented in great depth. Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, provides readers with a general reference for prostate cancer from prevention to therapy and will be of value to clinicians, scientists, and administrators who strive to solve the cancer problem.
Author: Philippe E. Spiess
Publisher: IntechOpen
ISBN: 9789533073316
Category : Medical
Languages : en
Pages : 530
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Book Description
The present textbook highlights many of the exciting discoveries made in the diagnosis and treatment of prostate cancer over the past decade. International thought leaders have contributed to this effort providing a comprehensive and state-of-the art review of the signaling pathways and genetic alterations essential in prostate cancer. This work provides an essential resource for healthcare professionals and scientists dedicated to this field. This textbook is dedicated to the efforts and advances made by our scientific community, realizing we have much to learn in striving to some day in the not too distant future cure this disease particularly among those with an aggressive tumor biology.
