Public Health Risk Assessment for Human Exposure to Chemicals

Public Health Risk Assessment for Human Exposure to Chemicals PDF Author: K. Asante-Duah
Publisher: Springer Science & Business Media
ISBN: 9401004811
Category : Medical
Languages : en
Pages : 352

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Book Description
In fact, with the control and containment of most infectious conditions and diseases of the past millennium having been achieved in most developed countries, and with the resultant increase in life expectancies, much more attention seems to have shifted to degenerative health problems. Many of the degenerative health conditions have been linked to thousands of chemicals regularly encountered in human living and occupational/work environments. It is important, therefore, that human health risk assessments are undertaken on a consistent basis - in order to determine the potential impacts of the target chemicals on public health.

Public Health Risk Assessment for Human Exposure to Chemicals

Public Health Risk Assessment for Human Exposure to Chemicals PDF Author: K. Asante-Duah
Publisher: Springer Science & Business Media
ISBN: 9401004811
Category : Medical
Languages : en
Pages : 352

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Book Description
In fact, with the control and containment of most infectious conditions and diseases of the past millennium having been achieved in most developed countries, and with the resultant increase in life expectancies, much more attention seems to have shifted to degenerative health problems. Many of the degenerative health conditions have been linked to thousands of chemicals regularly encountered in human living and occupational/work environments. It is important, therefore, that human health risk assessments are undertaken on a consistent basis - in order to determine the potential impacts of the target chemicals on public health.

Phthalates and Cumulative Risk Assessment

Phthalates and Cumulative Risk Assessment PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309128412
Category : Nature
Languages : en
Pages : 208

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Book Description
People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.

Science and Judgment in Risk Assessment

Science and Judgment in Risk Assessment PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030904894X
Category : Science
Languages : en
Pages : 668

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Book Description
The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.

Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment

Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309112982
Category : Science
Languages : en
Pages : 300

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Book Description
The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new waysâ€"an effort requiring funding, interagency coordination, and data management strategies.

Human Exposure to Electromagnetic Fields

Human Exposure to Electromagnetic Fields PDF Author: Patrick Staebler
Publisher: John Wiley & Sons
ISBN: 1119384524
Category : Science
Languages : en
Pages : 371

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Book Description
Everyone, whether they like it or not, is exposed to electromagnetic fields, most of the time, at very low levels. In this case, they are inconsequential, but they can cause adverse health effects when they become intense enough. This topic is complex and sensitive. Covering frequencies from 0 Hz to 300 GHz, Human Exposure to Electromagnetic Fields provides an overview of this vast topic. After a reminder of the concepts of electromagnetic fields, the author presents some examples of sources of radiation in daily life and in the industrial or medical sectors. The biophysical and biological effects of these fields on the human body are detailed and the exposure limits are recalled. The exposure assessment and the implementation of the appropriate regulation within companies are also covered. Technically and practically, this book is aimed at people with a scientific background, risk prevention actors, health physicians, especially occupational doctors, and equipment designers.

Possible Health Effects of Exposure to Residential Electric and Magnetic Fields

Possible Health Effects of Exposure to Residential Electric and Magnetic Fields PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309054478
Category : Science
Languages : en
Pages : 379

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Book Description
Can the electric and magnetic fields (EMF) to which people are routinely exposed cause health effects? This volume assesses the data and draws conclusions about the consequences of human exposure to EMF. The committee examines what is known about three kinds of health effects associated with EMF: cancer, primarily childhood leukemia; reproduction and development; and neurobiological effects. This book provides a detailed discussion of hazard identification, dose-response assessment, exposure assessment, and risk characterization for each. Possible Health Effects of Exposure to Residential Electric and Magnetic Fields also discusses the tools available to measure exposure, common types of exposures, and what is known about the effects of exposure. The committee looks at correlations between EMF exposure and carcinogenesis, mutagenesis, neurobehavioral effects, reproductive and developmental effects, effects on melatonin and other neurochemicals, and effects on bone healing and stimulated cell growth.

Air Pollution, the Automobile, and Public Health

Air Pollution, the Automobile, and Public Health PDF Author: Sponsored by The Health Effects Institute
Publisher: National Academies Press
ISBN: 0309037263
Category : Science
Languages : en
Pages : 703

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Book Description
"The combination of scientific and institutional integrity represented by this book is unusual. It should be a model for future endeavors to help quantify environmental risk as a basis for good decisionmaking." â€"William D. Ruckelshaus, from the foreword. This volume, prepared under the auspices of the Health Effects Institute, an independent research organization created and funded jointly by the Environmental Protection Agency and the automobile industry, brings together experts on atmospheric exposure and on the biological effects of toxic substances to examine what is knownâ€"and not knownâ€"about the human health risks of automotive emissions.

Occupational Exposure Assessment for Air Contaminants

Occupational Exposure Assessment for Air Contaminants PDF Author: Gurumurthy Ramachandran
Publisher: CRC Press
ISBN: 1420032151
Category : Technology & Engineering
Languages : en
Pages : 357

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Book Description
Addressing occupational exposure assessment for air contaminants as a coherent body of knowledge, this is the first book to explore occupational air contaminant measurement and properties, human exposure assessment, design of exposure strategies, and the statistical interpretation of exposure measurements in one comprehensive source. The book covers both the technological aspects of measuring air contaminants and the occupational hygiene framework within which such measurements take place. The all-inclusive exploration of the major theories and practices of occupational exposure assessment for air contaminants make this an ideal textbook for graduate or upper-level undergraduate courses.

Controlled Human Inhalation-Exposure Studies at EPA

Controlled Human Inhalation-Exposure Studies at EPA PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 030945252X
Category : Science
Languages : en
Pages : 159

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Book Description
The U.S. Environmental Protection Agency (EPA) has a mission and regulatory responsibility to protect human health and the environment. EPA's pursuit of that goal includes a variety of research activities involving human subjects, such as epidemiologic studies and surveys. Those research activities also involve studies of individuals who volunteer to be exposed to air pollutants intentionally in controlled laboratory settings so that measurements can be made of transient and reversible biomarker or physiologic responses to those exposures that can indicate pathways of toxicity and mechanisms of air-pollution responses. The results of those controlled human inhalation exposure (CHIE) studies, also referred to as human clinical studies or human challenge studies, are used to inform policy decisions and help establish or revise standards to protect public health and improve air quality. Controlled Human Inhalation-Exposure Studies at EPA addresses scientific issues and provides guidance on the conduct of CHIE studies. This report assesses the utility of CHIE studies to inform and reduce uncertainties in setting air-pollution standards to protect public health and assess whether continuation of such studies is warranted. It also evaluates the potential health risks to test subjects who participated in recent studies of air pollutants at EPA's clinical research facility.

Human and Ecological Risk Assessment

Human and Ecological Risk Assessment PDF Author: Dennis J. Paustenbach
Publisher: John Wiley & Sons
ISBN: 1119441331
Category : Science
Languages : en
Pages : 1476

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Book Description
Human and Ecological Risk Assessment: Theory and Practice assembles the expertise of more than fifty authorities from fifteen different fields, forming a comprehensive reference and textbook on risk assessment. Containing two dozen case studies of environmental or human health risk assessments, the text not only presents the theoretical underpinnings of the discipline, but also serves as a complete handbook and "how-to" guide for individuals conducting or interpreting risk assessments. In addition, more than 4,000 published papers and books in the field are cited. Editor Dennis Paustenbach has assembled chapters that present the most current methods for conducting hazard identification, dose-response and exposure assessment, and risk characterization components for risk assessments of any chemical hazard to humans or wildlife (fish, birds, and terrestrials). Topics addressed include hazards posed by: Air emissions Radiological hazards Contaminated soil and foods Agricultural hazards Occupational hazards Consumer products and water Hazardous waste sites Contaminated air and water The bringing together of so many of the world's authorities on these topics, plus the comprehensive nature of the text, promises to make Human and Ecological Risk Assessment the text against which others will be measured in the coming years.